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1.
BMJ Case Rep ; 14(10)2021 Oct 14.
Artigo em Inglês | MEDLINE | ID: mdl-34649855

RESUMO

A woman in her 30s with underlying Graves' disease, who recently completed radioactive iodine treatment, presented with 2 weeks of acutely altered behaviour associated with auditory hallucinations and religious preoccupations. Laboratory investigation demonstrated elevated free thyroxine levels and suppressed thyroid-stimulating hormone levels. Additionally, there was a presence of antithyroid peroxidase antibodies consistent with autoimmune thyroid disease. She responded to antipsychotics and achieved biochemical euthyroidism. Subsequently, antipsychotic was tapered off during outpatient follow-up at the patient's own request, with supplement thyroxine continuing. After 1 week, acute hallucinations and religious preoccupations re-emerged, driving her to inflict self-injuries by swallowing coins and nails and banging her head against the wall, sustaining laceration wounds. Furthermore, she hammered a roofing nail into the external genitalia, embedded in the symphysis pubis. After supplemental thyroxine was stopped and olanzapine was started, she achieved biochemical euthyroid followed by remission of psychosis within 1 week. This case illustrates the importance of elucidating organic causes of psychosis as they are easily and swiftly reversible.


Assuntos
Hipertireoidismo , Transtornos Psicóticos , Comportamento Autodestrutivo , Neoplasias da Glândula Tireoide , Feminino , Humanos , Hipertireoidismo/complicações , Hipertireoidismo/tratamento farmacológico , Radioisótopos do Iodo , Transtornos Psicóticos/tratamento farmacológico , Transtornos Psicóticos/etiologia , Comportamento Autodestrutivo/complicações , Tiroxina/uso terapêutico
2.
Ann Palliat Med ; 10(9): 9607-9613, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34628886

RESUMO

BACKGROUND: Adolescents are a high-risk group for non-suicidal self-injury (NSSI), which seriously affects their physical and mental health. This study aimed to explore the risk factors for depressive adolescents with NSSI. METHODS: A total of 153 adolescents with depression were divided into the NSSI group (n=65) and non-NSSI group (n=88) according to the criteria stipulated by Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5). The Beck scale for suicidal ideation (BSS), adolescent self-rating life events checklist (ASLEC), family adaptability and cohesion evaluation scale II-Chinese version (FACES II-CV), childhood trauma questionnaire short form (CTQ SF), and multidimensional scale of perceived social support (MSPSS) were applied to evaluate suicidal ideation, frequency and intensity of stressful life events, family functions, childhood trauma, and perceived support, respectively. We applied two-dimensional logistic regression to identify risk factors for NSSI. RESULTS: Female gender ratio, suicidal ideation, and attempted suicide were significantly higher in the NSSI group than in the non-NSSI group (all P<0.05). Scores of interpersonal relationships in ASLEC, emotional abuse, and emotional neglect in the CTQ-SF were significantly higher in the NSSI group than those in the non-NSSI group (all P<0.001). The scores of family cohesion (P=0.001) and family adaptability (P=0.01) were significantly lower in the NSSI group than in the non-NSSI group. The MSPSS was used to assess support from the family, and the index was significantly lower in the NSSI group (P<0.001). After adjusting for age and gender, BSS score, interpersonal relationship score, emotional abuse score, and emotional neglect score were identified as independent risk factors for NSSI. CONCLUSIONS: The rate of NSSI in adolescents with depression is high. Higher scores of BSS, interpersonal relationship, emotional abuse, and neglect were independently associated with NSSI.


Assuntos
Depressão , Comportamento Autodestrutivo , Adolescente , Criança , Feminino , Humanos , Fatores de Risco , Ideação Suicida , Tentativa de Suicídio
3.
J Pak Med Assoc ; 71(9): 2143-2147, 2021 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-34580503

RESUMO

OBJECTIVE: To identify the association among suicidal ideation, deliberate self-harm, and psychopathological distress in normal and deliberate self-harm adults. METHODS: The cross-sectional study was conducted at the Department of Psychiatry, Military Hospital, Rawalpindi, Pakistan, from January to July 2017, and comprised deliberate self harm and normal adults aged 18-25 years. Psychiatric evaluation involved a semi-structured interview based on mental status examination. The self-harm tendency was assessed on the basis of self-harm inventory of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders. Beck scale for suicide ideation and he depression anxiety and stress scale were also used for data collection. Data was analysed using SPSS 22. RESULTS: There were 200 subjects with a mean age of 20.89±9.06 years; 100(50%) each in deliberate self-harm and normal groups. Deliberate self-harm was significantly positively associated with suicidal ideation and mental health problems, including depression, anxiety and stress (p<0.05). Deliberate self-harm tendency was also positively associated with mental health problems in normal adults (p<0.05). Normal adults had higher level of mental health problems, such as depression and stress, compared to deliberate self harm adults (p<0.05). Adults having self-harm behaviour were more inclined to have suicidal ideation compared to normal adults behaviour (p<0.05). CONCLUSIONS: Deliberate self-harm was found to be strongly related to suicidal behaviour and mental health issues in both normal and deliberate self-harm adults.


Assuntos
Transtornos Mentais , Comportamento Autodestrutivo , Adolescente , Adulto , Criança , Estudos Transversais , Humanos , Masculino , Pacientes Ambulatoriais , Fatores de Risco , Comportamento Autodestrutivo/epidemiologia , Ideação Suicida , Adulto Jovem
4.
BMC Musculoskelet Disord ; 22(1): 757, 2021 Sep 04.
Artigo em Inglês | MEDLINE | ID: mdl-34481480

RESUMO

BACKGROUND: The prevention of self-harm is an international public health priority. It is vital to identify at-risk populations, particularly as self-harm is a risk factor for suicide. This study aims to examine the risk of self-harm in people with vertebral fractures. METHODS: Retrospective cohort study. Patients with vertebral fracture were identified within the Clinical Practice Research Datalink and matched to patients without fracture by sex and age. Incident self-harm was defined by primary care record codes following vertebral fracture. Overall incidence rates (per 10,000 person-years (PY)) were reported. Cox regression analysis determined risk (hazard ratios (HR), 95 % confidence interval (CI)) of self-harm compared to the matched unexposed cohort. Initial crude analysis was subsequently adjusted and stratified by median age and sex. RESULTS: The number of cases of vertebral fracture was 16,293, with a matched unexposed cohort of the same size. Patients were predominantly female (70.1 %), median age was 76.3 years. Overall incidence of self-harm in the cohort with vertebral fracture was 12.2 (10.1, 14.8) /10,000 PY. There was an initial crude association between vertebral fracture and self-harm, which remained after adjustment (HR 2.4 (95 %CI 1.5, 3.6). Greatest risk of self-harm was found in those with vertebral fractures who were aged below 76.3 years (3.2(1.8, 5.7)) and male (3.9(1.8, 8.5)). CONCLUSIONS: Primary care patients with vertebral fracture are at increased risk of self-harm compared to people without these fractures. Male patients aged below 76 years of age appear to be at greatest risk of self-harm. Clinicians need to be aware of the potential for self-harm in this patient group.


Assuntos
Comportamento Autodestrutivo , Fraturas da Coluna Vertebral , Idoso , Estudos de Coortes , Feminino , Humanos , Incidência , Masculino , Estudos Retrospectivos , Fatores de Risco , Comportamento Autodestrutivo/diagnóstico , Comportamento Autodestrutivo/epidemiologia , Fraturas da Coluna Vertebral/epidemiologia
5.
Artigo em Russo | MEDLINE | ID: mdl-34481436

RESUMO

A screening study on non-suicidal self-injurious behavior in men of military age was conducted. OBJECTIVE: Study was aimed to determine the prevalence, structure and causes of non-suicidal self-injuries in 193 men aged 19.68±2.07. METHOD: Assessment of non-suicidal self-injury (NSSI) was performed with clinical interview and the scale on self-harm behavior (Polskaya, 2014). RESULTS: The study revealed that 38.7% (75 persons) in the sample committed an act of self-harm at least once in their life. The most common acts of instrumental self-harm were striking with a fist, leg, head or body by hard surfaces and self-cutting. Among somatic self-harm, nail biting, lip, cheeks and tongue biting, as well as skin combing and creating obstacles for wound healing were founded. CONCLUSION: Non-suicidal self-injurious behavior of persons of military age presented by the tools and somatic self-harm and caused by the factors of «regaining control over emotions¼, «impact on others¼, «stress relief¼.


Assuntos
Militares , Comportamento Autodestrutivo , Emoções , Humanos , Masculino , Prevalência , Comportamento Autodestrutivo/diagnóstico , Comportamento Autodestrutivo/epidemiologia , Ideação Suicida
6.
Aquichan ; 21(3): e2133, sept. 30, 2021.
Artigo em Inglês, Português | LILACS, BDENF - Enfermagem, COLNAL | ID: biblio-1292395

RESUMO

Objetivo: identificar a prevalência de lesão autoprovocada notificada entre adolescentes no Espírito Santo e analisar os fatores associados. Materiais e métodos: estudo analítico do tipo transversal, com os dados notificados de violência autoprovocada entre adolescentes no Espírito Santo registrados no Sistema de Informação de Agravos e Notificação de 2011 a 2018. Análises bivariadas consideraram o teste Qui-Quadrado (χ²) e o exato de Fisher. A análise multivariada considerou o modelo log-binomial, e os resultados do ajuste foram apresentados em razão de prevalência. Resultados: a prevalência de lesão autoprovocada notificada foi 33 % e, desse total, 79,8 % ocorreram entre adolescentes do sexo feminino. Houve maior prevalência em adolescentes com idade de 13 a 17 anos (sexo feminino) e de 18 a 19 anos (sexo masculino), e entre aqueles com deficiência ou transtorno. Maiores prevalências foram encontradas na residência e na habitação coletiva, e entre aqueles que não consumiram álcool no evento. No sexo feminino, também houve associação com a zona urbana (p < 0,05). Conclusões: percebe-se a alta prevalência de lesão autoprovocada notificada entre os adolescentes no Espírito Santo e os fatores associados a esse fenômeno. Constata-se a importância da adoção de medidas de promoção, prevenção e recuperação contra o agravo.


Objetivo: identificar la prevalencia de lesiones autoprovocadas notificadas entre adolescentes en Espírito Santo, Brasil, y analizar los factores asociados. Materiales y métodos: estudio analítico de tipo transversal, a partir de datos notificados de violencia autoprovocada entre adolescentes en Espírito Santo registrados en el Sistema de Información de Problemas de Salud y Notificación entre 2011 y 2018. En los análisis bivariados se consideraron las pruebas de chi-cuadrado (χ²) y exacta de Fisher. El análisis multivariado adoptó el modelo log-binomial, y los resultados del ajuste se presentaron a partir de la razón de prevalencia. Resultados: la prevalencia de lesiones autoprovocadas notificadas fue del 33 % y, de este total, el 79,8 % ocurrió entre adolescentes del género femenino. La prevalencia fue mayor en adolescentes de 13 a 17 años (sexo femenino) y de 18 y 19 años (sexo masculino), y entre aquellos con alguna discapacidad o trastorno. Se encontraron valores de prevalencia más elevados en la vivienda y en alojamiento compartido, y entre aquellos que no consumieron alcohol en el evento en cuestión. En el sexo femenino, también se registró una asociación con el área urbana (p < 0,05). Conclusiones: se percibe la elevada prevalencia de lesiones autoprovocadas notificadas entre los adolescentes en Espírito Santo y los factores asociados a este fenómeno. Se evidencia la importancia de adoptar medidas de promoción, prevención y recuperación del problema.


Objective: To identify the prevalence of notified self-inflicted injuries among adolescents in Espírito Santo and to analyze the associated factors. Materials and methods: A cross-sectional and analytical study, with the notified data of self-inflicted violence among adolescents in Espírito Santo registered in the Notifiable Diseases Information System from 2011 to 2018. The bivariate analyses considered the Chi-square (χ²) and Fisher's Exact tests. The multivariate analysis considered the log-binomial model, and the adjustment results were presented as prevalence ratio. Results: The prevalence of notified self-inflicted injuries was 33 % and, of this total, 79.8 % occurred among female adolescents. Prevalence was higher among adolescents aged from 13 to 17 years old (female gender) and from 18 to 19 years old (male gender), as well as among those with some disability or disorder. Higher prevalence values were found in the residence and in collective housing, as well as among those who did not consume alcohol at the event in question. In the female gender, there was also an association with the urban area (p < 0.05). Conclusions: High prevalence of notified self-inflicted injuries is perceived among adolescents in Espírito Santo, as well as of the factors associated to this phenomenon. The importance of adopting promotion, prevention and recovery measures for the problem is verified.


Assuntos
Tentativa de Suicídio , Epidemiologia , Adolescente , Comportamento Autodestrutivo , Sistemas de Informação em Saúde
7.
Nutrients ; 13(8)2021 Aug 13.
Artigo em Inglês | MEDLINE | ID: mdl-34444939

RESUMO

Globally, almost four and a half million people died from injury in 2019. Alcohol's contribution to injury-related premature loss of life, disability and ill-health is pervasive, touching individuals, families and societies throughout the world. We conducted a review of research evidence for alcohol's causal role in injury by focusing on previously published systematic reviews, meta-analyses and where indicated, key studies. The review summarises evidence for pharmacological and physiological effects that support postulated causal pathways, highlights findings and knowledge gaps relevant to specific forms of injury (i.e., violence, suicide and self-harm, road injury, falls, burns, workplace injuries) and lays out options for evidence-based prevention.


Assuntos
Consumo de Bebidas Alcoólicas/efeitos adversos , Etanol/efeitos adversos , Ferimentos e Lesões/epidemiologia , Acidentes por Quedas/estatística & dados numéricos , Acidentes de Trânsito/estatística & dados numéricos , Queimaduras/epidemiologia , Feminino , Carga Global da Doença , Saúde Global , Política de Saúde , Humanos , Masculino , Traumatismos Ocupacionais/epidemiologia , Fatores de Risco , Comportamento Autodestrutivo/epidemiologia , Suicídio/estatística & dados numéricos , Violência/estatística & dados numéricos , Local de Trabalho , Ferimentos e Lesões/etiologia , Ferimentos e Lesões/prevenção & controle
8.
Medicine (Baltimore) ; 100(31): e26747, 2021 Aug 06.
Artigo em Inglês | MEDLINE | ID: mdl-34397817

RESUMO

OBJECTIVE: The incidence of non-suicidal self-injury (NSSI) behavior in adolescents is increasing year by year. Patients with a history of both depression and NSSI behavior tend to be at greater risk for suicide. At present, the mechanism of adolescent depressive disorder with NSSI behavior is not clear and still in research and exploration. The expression of the Silent Information Regulator 2 Related Enzyme 1 (SIRT1) gene is closely related to the level of serotonin in molecular mechanisms, and may be closely related to the occurrence and development of depressive disorder. This study aimed to explore the relationship between the SIRT1 gene and NSSI behaviors in adolescents with depressive disorder. METHODS: A total of 15 adolescent depressed patients with NSSI behavior and 15 healthy controls were enrolled in the study. Bisulfite Sequencing PCR (BSP) was used to test the methylation level of SIRT1 gene promoter region of the participants. The real-time fluorescent quantitative PCR was conducted to measure the mRNA expression level of SIRT1 gene. RESULTS: Our study found that the methylation level of SIRT1 gene promoter region at cytosine-guanine dinucleotide 5 (CpG5) site in depression group was higher than that of control group. Compared with that of control group, the plasma concentration of Sirt1 protein significantly decreased in depression group. CONCLUSION: Our study investigated the methylation level and the mRNA expression of SIRT1 gene in adolescent depressive patients with NSSI behavior. The study points towards finding an in vivo molecular marker for those adolescent patients.


Assuntos
Transtorno Depressivo/genética , Adolescente , Comportamento do Adolescente/psicologia , Distribuição de Qui-Quadrado , China/epidemiologia , Transtorno Depressivo/epidemiologia , Transtorno Depressivo/psicologia , Feminino , Voluntários Saudáveis , Humanos , Masculino , Metilação , RNA Mensageiro/genética , Fatores de Risco , Comportamento Autodestrutivo/epidemiologia , Comportamento Autodestrutivo/genética , Comportamento Autodestrutivo/psicologia , Sirtuína 1
9.
BMC Public Health ; 21(1): 1561, 2021 08 17.
Artigo em Inglês | MEDLINE | ID: mdl-34404376

RESUMO

BACKGROUND: Published studies examining the association between childhood maltreatment (CM) and self-harm (SH) among adolescents have been accumulated. It is possible that resilience serves as a moderator or mediator in CM-SH association, nevertheless, this topic has never been thoroughly investigated. METHODS: In this population-based cross-sectional study, we surveyed 3146 students aged 10-17 in southwest China. The Childhood Trauma Questionnaire (CTQ), the Modified version of Adolescents Self-Harm Scale (MASHS), and the Resilience Scale for Chinese Adolescents (RSCA) were used to measure CM, SH, and resilience. Correlational analyses, hierarchical multivariate linear regression, and structural equation modeling (SEM) were performed to test the moderation and mediation of resilience in CM-SH association. RESULTS: Findings revealed that, resilience with its five dimensions, CM, and SH were significantly correlated with each other. Resilience partially moderated and mediated the association between CM and SH. Besides, among all dimensions of resilience, emotion regulation, interpersonal assistance, and family support presented the strongest mediation in CM-SH association. CONCLUSIONS: Our results highlight the importance of resilience in CM related SH among Chinese teenagers. Resilience-oriented intervention could be considered in SH intervention measures for adolescents who had experienced CM.


Assuntos
Maus-Tratos Infantis , Comportamento Autodestrutivo , Adolescente , Criança , China/epidemiologia , Estudos Transversais , Humanos , Comportamento Autodestrutivo/epidemiologia , Estudantes , Inquéritos e Questionários
10.
Psychiatry Res ; 304: 114152, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34371298

RESUMO

The objective of this study was to conduct an ecologically valid test of etiological models of deliberate self-harm (DSH) during the COVID-19 pandemic. Using a sample of Canadian adolescents, we investigated: (1) the association between COVID-19-related stress and DSH; (2) whether emotion regulation (ER) difficulties mediated/moderated this association, including whether these effects differed by age; and (3) whether the mediating/moderating effects of ER difficulties were stronger among socially distanced youth. Canadian adolescents (N = 809) aged 12-18 were recruited on social media and completed an online survey. COVID-19-related stress was associated with recent DSH. Nonacceptance of emotional responses and limited access to ER strategies fully mediated this association. The indirect effect through nonacceptance of emotional responses was stronger among more socially distanced youth, whereas the indirect effect through limited access to ER strategies was stronger among older and more socially distanced youth. COVID-19-related stress and ER difficulties did not interact to predict DSH, nor did age or social distancing moderate these interactions. These results align with etiological models proposing central roles for stress and ER difficulties in DSH. Furthermore, this study underscores a need to support adolescents, particularly older teens with reduced in-person interactions, in adaptively coping with pandemic-related stress.


Assuntos
COVID-19 , Regulação Emocional , Comportamento Autodestrutivo , Adolescente , Canadá , Humanos , Pandemias , Distanciamento Físico , SARS-CoV-2 , Comportamento Autodestrutivo/epidemiologia
11.
Eur Heart J ; 42(33): 3172-3174, 2021 08 31.
Artigo em Inglês | MEDLINE | ID: mdl-34355759
12.
Lancet Psychiatry ; 8(10): 892-900, 2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34332697

RESUMO

BACKGROUND: There is widespread concern over the impact of public health measures, such as lockdowns, associated with COVID-19 on mental health, including suicide. High-quality evidence from low-income and middle-income countries, where the burden of suicide and self-harm is greatest, is scarce. We aimed to determine the effect of the pandemic on hospital presentations for self-poisoning. METHODS: In this interrupted time-series analysis, we established a new self-poisoning register at the tertiary care Teaching Hospital Peradeniya in Sri Lanka, a lower-middle-income country. Using a standard extraction sheet, data were gathered for all patients admitted to the Toxicology Unit with self-poisoning between Jan 1, 2019, and Aug 31, 2020. Only patients classified by the treating clinician as having intentionally self-poisoned were included. Data on date of admission, age or date of birth, sex, and poisoning method were collected. No data on ethnicity were available. We used interrupted time-series analysis to calculate weekly hospital admissions for self-poisoning before (Jan 1, 2019-March 19, 2020) and during (March 20-Aug 31, 2020) the pandemic, overall and by age (age <25 years vs ≥25 years) and sex. Individuals with missing date of admission were excluded from the main analysis. FINDINGS: Between Jan 1, 2019, and Aug 31, 2020, 1401 individuals (584 [41·7%] males, 761 [54·3%] females, and 56 [4·0%] of unknown sex) presented to the hospital with self-poisoning and had date of admission data. A 32% (95% CI 12-48) reduction in hospital presentations for self-poisoning in the pandemic period compared with pre-pandemic trends was observed (rate ratio 0·68, 95% CI 0·52-0·88; p=0·0032). We found no evidence that the impact of the pandemic differed by sex (rate ratio 0·64, 95% CI 0·44-0·94, for females vs 0·85, 0·57-1·26, for males; pinteraction=0·43) or age (0·64, 0·44-0·93, for patients aged <25 years vs 0·81, 0·57-1·16, for patients aged ≥25 years; pinteraction=0·077). INTERPRETATION: This is the first study from a lower-middle-income country to estimate the impact of the pandemic on self-harm (non-fatal) accounting for underlying trends. If the fall in hospital presentations during the pandemic reflects a reduction in the medical treatment of people who have self-poisoned, rather than a true fall in incidence, then public health messages should emphasise the importance of seeking help early. FUNDING: Elizabeth Blackwell Institute University of Bristol, Wellcome Trust, and Centre for Pesticide Suicide Prevention. TRANSLATIONS: For the Sinhalese and Tamil translations of the abstract see Supplementary Materials section.


Assuntos
COVID-19/psicologia , Hospitalização/estatística & dados numéricos , Envenenamento/psicologia , Comportamento Autodestrutivo/psicologia , Adulto , COVID-19/complicações , COVID-19/diagnóstico , COVID-19/epidemiologia , Efeitos Psicossociais da Doença , Países em Desenvolvimento/estatística & dados numéricos , Feminino , Hospitalização/tendências , Humanos , Incidência , Análise de Séries Temporais Interrompida/métodos , Masculino , Envenenamento/epidemiologia , SARS-CoV-2/genética , Comportamento Autodestrutivo/epidemiologia , Sri Lanka/epidemiologia , Suicídio/prevenção & controle , Suicídio/psicologia
14.
BMC Psychiatry ; 21(1): 401, 2021 08 13.
Artigo em Inglês | MEDLINE | ID: mdl-34388998

RESUMO

BACKGROUND: In the current study we investigated impulsivity and negative life events in relation to non-suicidal self-injury (NSSI) in correctional settings. METHODS: A total of 141 male justice-involved juveniles participated in our cross-sectional study, aged between 14 and 21 years old (M = 17.75; SD = 1.38). Data collection took place in correctional institutions in Hungary. A binary logistic regression was conducted to investigate possible associations between NSSI, impulsivity and negative life events. RESULTS: Lifetime prevalence of NSSI was 53.9% (N = 76). In a binary logistic regression model, only negative romantic relationship events were significantly associated with the risk of current NSSI (OR = 1.29; 95% CI = [1.06-1.56]). Other types of negative life events (family-related, friendship-related), impulsivity, age and conviction status did not have a significant role in the model. CONCLUSIONS: The results suggest that juvenile offenders should receive additional support to manage stress that is associated with negative life events, especially problems in romantic relationships. It is essential to help young inmates to find an adaptive way of reducing stress caused by negative relationship life events.


Assuntos
Comportamento Autodestrutivo , Justiça Social , Adolescente , Adulto , Estudos Transversais , Humanos , Comportamento Impulsivo , Masculino , Prevalência , Comportamento Autodestrutivo/epidemiologia , Adulto Jovem
15.
BMC Psychiatry ; 21(1): 407, 2021 08 17.
Artigo em Inglês | MEDLINE | ID: mdl-34404392

RESUMO

BACKGROUND: Rapid socio-economic development makes China a unique laboratory for examining how lifestyle changes affect adolescent mental health. This study aims to identify joint trajectories of modifiable lifestyle indicators during pubertal transition and its associations with psychopathological outcomes. METHODS: A cohort of 1974 children aged 7-9 years were recruited in Anhui Province, China during March 2013. The assessment of lifestyle behaviors (screen time, physical activity, sleep duration and beverage intake) and depressive symptoms were conducted from Wave 1 to Wave 4 (2018). Suicide ideation, non-suicidal self-harm (NSSI) and alcohol use were self-reported at Wave 4. Longitudinal trajectories of lifestyle patterns were defined using group-based multi-trajectory models in 2019. RESULTS: Four lifestyle trajectories were identified: persistent healthy (39.9%), suboptimal healthy (25.3%), unhealthy mitigation (17.2%), and persistent unhealthy (17.7%). Compared with persistent healthy group, the risk of subsequent suicide ideation [odds ratio (OR): 2.86, 95%CI: 2.15-3.81], depressive symptoms (OR: 2.16, 95%CI: 1.39-3.35), alcohol use (OR: 2.53, 95%CI: 1.78-3.61) and non-suicidal self-harm (OR: 1.35, 95%CI: 1.09-1.67) was significantly higher in persistent unhealthy group. CONCLUSIONS: This study provided convincing evidence that unhealthy lifestyle trajectory during adolescence is associated with more than two-fold elevated odds for multiple domains of psychopathological outcomes over 5 years.


Assuntos
Transtornos Mentais , Comportamento Autodestrutivo , Adolescente , Criança , Humanos , Estilo de Vida , Psicopatologia , Fatores de Risco , Comportamento Autodestrutivo/epidemiologia , Ideação Suicida
16.
BMC Psychiatry ; 21(1): 389, 2021 08 04.
Artigo em Inglês | MEDLINE | ID: mdl-34348675

RESUMO

BACKGROUNDS: Non-suicidal self-injury is a serious health problem among patients with depression or bipolar disorder. However, few studies within the Chinese context have investigated the prevalence of NSSI and its risk factors in above populations. The purpose of this study was to investigate the prevalence of non-suicidal self-injury and its risk factors in patients with depression or bipolar disorder in China. METHODS: The final sample comprised of 394 inpatients(Mage = 29.71; SDage = 11.95) with depression or bipolar disorder from two psychiatric hospitals in Beijing, China. A General Demographic Data Form, the Non-suicidal Self-injury Questionnaire(NSSI-Q), Impulsivity Item and the Adverse Childhood Experiences-International Questionnaire(ACE-IQ) were completed by all patients. RESULTS: Of the 394 patients examined, 245(62.2%) of this sample reported NSSI in past year. Of the 245 patients with NSSI, 135(55.1%) were diagnosed with depression and 110(44.9%) were diagnosed with bipolar disorder. The most common methods of NSSI for female was "pinching"(23.1%) and "scratching"(22.8%), while for male it was "hiting hard objects"(12.7%). By multivariate regression analysis, young age, unemployment, a higher monthly family income, single, impulsivity, long duration of illness and ACEs were risk factors for NSSI in patients with depression and bipolar disorder(P<0.05). CONCLUSIONS: Our study points to the fact that there was an unfortunate message about the prevalence of NSSI among patients with depression or bipolar disorder in China. It is necessary not only to raise the awareness of NSSI in families and society, but also to formulate targeted assessment and intervention. Moreover, future research should not only focus on individuals being hospitalized, but should be representative of individuals treated at home or in the community because there are no national statistics on NSSI among such patients in China.


Assuntos
Transtorno Bipolar , Comportamento Autodestrutivo , Adulto , Transtorno Bipolar/complicações , Transtorno Bipolar/epidemiologia , Criança , China/epidemiologia , Depressão , Feminino , Humanos , Masculino , Prevalência , Fatores de Risco , Comportamento Autodestrutivo/epidemiologia , Ideação Suicida
17.
Zh Nevrol Psikhiatr Im S S Korsakova ; 121(5. Vyp. 2): 12-18, 2021.
Artigo em Russo | MEDLINE | ID: mdl-34405652

RESUMO

OBJECTIVE: To study the clinical features of depressive disorders in adolescents with schizotypal disorder (STD). MATERIAL AND METHODS: Were examined 87 adolescents with STD (F21), taken for outpatient or inpatient observation in 2018-2020. Of these, 26 patients were selected (12 males, 14 females, mean age 12.7±2.9 years) diagnosed with clinically significant depression (F32). To assess the severity of depression, the Hamilton Depression Rating Scales (HDRS) and the Beck Depression Self-Assessment Questionnaire (BDI) were used. The SPQ questionnaire was used to quantify the presence of STD symptoms. RESULTS: Depressive disorders were observed in 28% of all examined patients with STD. Signs of dysontogenesis were observed in 92% of the examined. The duration of depressive episodes before the start of treatment averaged 8.7 months, and until therapeutic remission was achieved, an average of 12.6 years. A mild depressive episode according to the HDRS scale corresponded in 23.1% of patients with a moderate degree in 61.5% and a severe one in 3.8%. At the same time, according to the BDI questionnaire, the results were different: there was no mild degree of depression during treatment, moderate-severe degree was detected in 8 (30.1%) patients, in the remaining 16 (61.5%) - extremely severe degree. Suicidal thoughts were noted in 76.9% of the surveyed, while the parents knew about their presence only in 27.0% of adolescents. A suicidal attempt was made by 3 patients (11.5%), one of them repeatedly. Non-suicidal self-injurious behavior was found in 38.5% of patients. CONCLUSION: Depressive episodes in adolescents with STD are noted chkasto, characterized by the duration and severity of symptoms. Subjective depressive experiences, primarily internal feelings of longing, ideas of failure and guilt, as well as the frequency of anti-vital thoughts and self-injurious behavior, are much more pronounced in adolescents than they demonstrate in everyday life.


Assuntos
Transtorno Depressivo , Comportamento Autodestrutivo , Adolescente , Criança , Depressão/diagnóstico , Depressão/epidemiologia , Feminino , Humanos , Masculino , Escalas de Graduação Psiquiátrica , Ideação Suicida , Tentativa de Suicídio
18.
Artigo em Inglês | MEDLINE | ID: mdl-34444105

RESUMO

Non-suicidal self-injury (NSSI) is an emerging health problem among adolescents. Although previous studies have shown that deviant peer affiliation is an important risk factor for this behavior, the reasons for this relationship are unclear. Based on the integrated theoretical model of the development and maintenance of NSSI and the social development model of delinquency prevention, this study tested whether depression mediated the relationship between deviant peer affiliation and NSSI and whether this mediating effect was moderated by sensation seeking. A sample of 854 Chinese adolescents (31.50% male; Mage = 16.35; SD = 1.15) anonymously completed questionnaires on the study variables. Results of regression-based analyses showed that depression mediated the association between deviant peer affiliation and NSSI, and this effect was stronger among adolescents who reported high sensation seeking. The results demonstrate the role of individual differences in the link between affiliation with deviant peers and NSSI, and have implications for preventing and treating this risky behavior.


Assuntos
Comportamento do Adolescente , Comportamento Autodestrutivo , Adolescente , China/epidemiologia , Depressão/epidemiologia , Feminino , Humanos , Masculino , Grupo Associado , Comportamento Autodestrutivo/epidemiologia , Sensação
19.
Behav Ther ; 52(5): 1055-1066, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34452661

RESUMO

Impairments in interoception have been linked to self-injurious behaviors, and capability for suicide may account for this relationship. However, past studies have relied primarily on self-report and unidimensional measures. The present study aimed to replicate and extend previous findings by examining the relationship between interoceptive dysfunction, pain tolerance, and self-injurious behaviors using a multidimensional and multi-method approach. A sample of 245 undergraduate students (Mage = 19.27 years, SD = 2.81; 73.7% female, 72.% White/European American), who reported lifetime suicidal ideation on a screening survey completed a battery of self-report measures, four counterbalanced pain tolerance tasks, and a clinical interview assessing their self-injurious behaviors. A tendency to stay attuned to bodily sensations was significantly related to decreased pain tolerance. Only trust in one's body was significantly related to decreased presence of lifetime suicide attempts. No other facets of interoception or pain tolerance were significantly associated with self-injurious behaviors. Overall, these findings contrast with previous findings that capability for suicide may account for relations between interoceptive dysfunction and self-injurious behaviors. Nonetheless, the results of this study provide important information on the factor structure of interoceptive dysfunction and pain tolerance, and highlight the importance of careful selection of measures and operationalization of key constructs, particularly interoceptive dysfunction and pain tolerance.


Assuntos
Interocepção , Comportamento Autodestrutivo , Adulto , Feminino , Humanos , Masculino , Limiar da Dor , Ideação Suicida , Tentativa de Suicídio , Adulto Jovem
20.
Behav Ther ; 52(5): 1123-1136, 2021 09.
Artigo em Inglês | MEDLINE | ID: mdl-34452667

RESUMO

Nonsuicidal self-injury (NSSI) is a prevalent and dangerous behavior. Those with a history of NSSI often report high levels of self-critical rumination (SCR), a form of negatively valenced introspective self-referential processing. It is plausible that this overly analytical style of relating to the self might hinder the ability to process interoceptive signals, thereby increasing the capacity to engage in behaviors that cause bodily harm. Two studies investigated whether trait or state SCR influenced aspects of interoception in those with and without a history of NSSI. In Study 1 (N = 180), irrespective of NSSI history, trait SCR was associated with finding attending to the heartbeat unpleasant. However, no associations were observed for interoceptive confidence, or metacognitive insight into their interoceptive abilities (confidence-accuracy correspondence). Trait SCR was associated with having higher interoceptive accuracy, but only in those without a history of NSSI. In Study 2 (N = 98), irrespective of NSSI history, state self-criticism led to a more negative interoceptive valence, and reduced participants' metacognitive insight. In those without a history of NSSI, state self-criticism also increased interoceptive accuracy-an effect attenuated in those with NSSI. These findings suggest that those with NSSI are characterized by a blunted interoceptive response to negatively valenced self-focused attention.


Assuntos
Interocepção , Comportamento Autodestrutivo , Atenção , Frequência Cardíaca , Humanos , Autoavaliação (Psicologia)
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