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1.
Artigo em Japonês | MEDLINE | ID: mdl-33612694

RESUMO

PURPOSE: To investigate the actual condition of the crystalline lens equivalent dose and effective dose according to the type of job and the type of duties in a medical institution. We also sought to clarify effective exposure reduction strategies. METHODS: Equivalent crystalline lens doses, effective doses, job type, and duties for 8656 persons · year were obtained from 17 medical facilities. We analyzed the relationship between the effective dose and the crystalline lens equivalent dose in uniform exposure control and non-uniform exposure control conditions. Exposure data were obtained for 13 unique job types and duties. RESULTS: The ratio of the lens equivalent dose to the effective dose of non-uniform exposure managers was 2 to 6 times and varied depending on the occupation. The percentage of persons whose annual lens equivalent dose exceeded 20 mSv was 4.75% for medical doctors, 1.17% for nurses, and 0.24% for radiological technologists. Highly exposed tasks included doctors in cardiology and gastroenterology performing angiography and endoscopy, nurses in endoscopy, and radiological technologists in radiography and CT examinations. CONCLUSION: Thorough unequal exposure control for operations with high crystalline lens exposure, radiation protection education, and effective use of proper personal protective equipment such as the use of radiation protection glasses may reduce lens exposure levels.


Assuntos
Cristalino , Exposição Ocupacional , Exposição à Radiação , Humanos , Corpo Clínico , Doses de Radiação
2.
BMJ Case Rep ; 14(2)2021 Feb 05.
Artigo em Inglês | MEDLINE | ID: mdl-33547123

RESUMO

A 6-year-old systemically healthy child presented with visual acuity of 1/60, N18 oculusdextrus (OD), and 6/18, N6 oculus sinister (OS). Slit-lamp biomicroscopy revealed suspicious bilateral inferotemporal pigmented ciliary body (CB) tumour, protruding posterior capsule and temporal posterior subcapsular cataract oculus uterque. Anterior segment optical coherence tomography, ultrasonography, ultrasonic biomicroscopy and Scheimpflug imaging revealed protruding posterior capsule and cortex abutting but not arising from CB suggestive of peripheral pigmented posterior lenticonus with hypermetropia (axial length 20.27 mm OD and 19.97 mm OS). Aberrometry revealed high internal aberrations and low Dysfunctional Lens Index (DLI). Lens aspiration with intraocular lens implantation in the bag OD and contact lens correction OS were undertaken. The child had a postoperative visual gain of 3/60, N18 with improved aberrometric profile OD, and was advised amblyopia therapy. Rarely posterior lenticonus can mimic a CB mass. Multi-modal ocular imaging can aid in its diagnosis and management. DLI may serve as a useful indicator of surgery in such cases.


Assuntos
Aberrações de Frente de Onda da Córnea/diagnóstico por imagem , Cristalino/anormalidades , Vítreo Primário Hiperplásico Persistente/diagnóstico por imagem , Vítreo Primário Hiperplásico Persistente/cirurgia , Criança , Aberrações de Frente de Onda da Córnea/cirurgia , Diagnóstico Diferencial , Humanos , Acuidade Visual
4.
Harefuah ; 159(12): 892-897, 2020 Dec.
Artigo em Hebraico | MEDLINE | ID: mdl-33369305

RESUMO

BACKGROUND: Several significant visual changes can occur during human aging. These include decreased visual acuity and binocular function, contraction of visual fields, presbyopia, dry eye, decreased contrast sensitivity, decreased dark adaptation, delayed glare recovery, change in color vision and decreased visual processing speed. The most common physical changes are decreased pupil size, decreased retinal luminance, changes in inter- and intracellular connections, both intra-retinal and connections to the cortex .There are changes both in quantity and physical location of various cells, such as photoreceptors ganglion and bipolar retinal cells, as well as changes in clarity of media such as the crystalline lens, all of which in turn cause the resulting visual changes. Among adversely affected tasks are near work such as reading and computer work, driving, maneuvering through crowded or unfamiliar surroundings, locating desired objects surrounded by clutter and even decreased balance ability that may cause falling. Some of the changes can be reversed or at least slowed, but some processes cannot be stopped. Some of the options at our disposal to help the patient can vary from early prevention, using single or a combination of external devices such as optical devices and various forms of medical treatments, surgical and other. Although the visual system is affected by other senses, vision also affects other systems in the body. The objective here is to isolate specifically visual-related changes that can occur as healthy people age and thereby expand the vocabulary and dialogue between health care providers with ophthalmologists and optometrists for ultimate better patient care. The following review attempts to present a brief current update of the accumulated data describing various physiological visual changes that can occur with aging in generally healthy individuals and in this article, disregards the effects of ocular diseases, even if they are usually associated with age.


Assuntos
Sensibilidades de Contraste , Cristalino , Envelhecimento , Humanos
5.
PLoS One ; 15(12): e0243416, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-33373370

RESUMO

AIMS: To compare the value of pre-treatment axial elongation (AE) and changes in refractive sphere (M change) for predicting the success in orthokeratology (ortho-k), in order to better identify suitable candidates for myopia control. METHODS: This study further analysed the data of 66 subjects receiving 7-month ortho-k treatment, following a 7-month observation period, during which single-vision spectacles were worn. Rate of myopia progression was determined by AE and M change and subjects categorised as slow, moderate, or rapid progressors based on these changes. Outcomes of myopia control, based on the AE reduction after ortho-k, were classified as 'ineffectual', 'clinically insignificant', or 'beneficial'. RESULTS: Of the 20 subjects, initially categorised as slow by AE and, of whom 95% were similarly categorised by M change, none benefitted from ortho-k. In contrast, of the 22 subjects with moderate AE, 77% and 23% displaying slow and moderate M change, respectively, the majority (73%) benefitted from ortho-k lens wear. The 24 subjects with rapid AE were poorly identified by M change, with only 21% correctly categorised. The vast majority of rapid progressors showed significant benefit after ortho-k. CONCLUSION: Progression of AE is a good indicator of subsequent success of ortho-k treatment. Delaying commencement of therapy is prudent for children with slow progression as results indicate that they would be unlikely to benefit from this intervention. As change in refractive error frequently underestimates rapid progression of AE, its value for identifying appropriate candidates for myopia control is poor.


Assuntos
Miopia Degenerativa/terapia , Miopia/terapia , Procedimentos Ortoceratológicos/métodos , Erros de Refração/fisiopatologia , Adolescente , Comprimento Axial do Olho/fisiopatologia , Criança , Lentes de Contato , Progressão da Doença , Óculos , Feminino , Humanos , Cristalino/patologia , Masculino , Miopia/patologia , Miopia Degenerativa/patologia , Prescrições , Refração Ocular/fisiologia
7.
Vestn Oftalmol ; 136(6): 26-31, 2020.
Artigo em Russo | MEDLINE | ID: mdl-33084276

RESUMO

All methods of laser radiation therapy currently used in clinical practice are positioned as safe in terms of possible negative effects on the eye and surrounding tissues. PURPOSE: To assess possible changes in the macular region of the retina and thickness of the peripapillary retinal nerve fiber layer (RNFL) according to the results of a dynamic study of OCT parameters after laser operations in the iris-lens diaphragm area. MATERIAL AND METHODS: Optical coherence tomography (OCT) was performed on 34 pseudophakic patients (43 eyes) with clinical signs of secondary cataract with best corrected visual acuity (BCVA) of at least 0.3, and on 28 patients (38 eyes) with relative papillary block before laser intervention and 1 hour, 1 day, 3 days, 7 days, 1 and 6 months after surgery. The changes in the thickness of the retina in 9 standard ETDRS areas, and the thickness of the ganglion cells layer and peripapillary RNFL were analyzed. RESULTS: In both groups of patients during the entire observation period, there was no fundamental change in the thickness of the peripapillary RNFL and the ganglion cell complex (all p>0.05). According to OCT, retinal thickness in both groups significantly increased an hour after laser irradiation in 5 out of 9 ETDRS areas. The retinal thickness returned to preoperative values in the group of patients with Nd:YAG laser posterior capsulotomy on the 3rd day after surgery, and after 1 week in the group with Nd:YAG laser iridectomy. Retinal thickness in the macular area did not change significantly during the follow-up. CONCLUSION: Laser operations in the iris-lens diaphragm area have a negligible effect on the thickness of the retina, as measured by the OCT method, do not affect the thickness of the ganglion cells layer or peripapillary RNFL, and is safe for the central zone of the retina.


Assuntos
Diafragma , Cristalino , Humanos , Iris/diagnóstico por imagem , Iris/cirurgia , Fibras Nervosas , Células Ganglionares da Retina
8.
Annu Int Conf IEEE Eng Med Biol Soc ; 2020: 1646-1649, 2020 07.
Artigo em Inglês | MEDLINE | ID: mdl-33018311

RESUMO

Lens structures segmentation on anterior segment optical coherence tomography (AS-OCT) images is a fundamental task for cataract grading analysis. In this paper, in order to reduce the computational cost while keeping the segmentation accuracy, we propose an efficient segmentation method for lens structures segmentation. At first, we adopt an efficient semantic segmentation network in the work, and used it to extract the lens area image instead of the conventional object detection method, and then used it once again to segment the lens structures. Finally, we introduce the curve fitting processing (CFP) on the segmentation results. Experiment results show that our method has good performance on accuracy and processing speed, and could be applied to CASIA II device for practical applications.


Assuntos
Cristalino , Lentes , Projetos de Pesquisa , Tomografia de Coerência Óptica
9.
Med Lav ; 111(4): 269-284, 2020 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-32869764

RESUMO

BACKGROUND: The eye is an important sensory organ occupationally exposed to ionizing radiation (IR) in healthcare workers (HCWs) engaged in medical imaging (MI). New evidence highlights the possible induction of cataract at IR exposure levels to be much lower than expected in the past. OBJECTIVE: Conduct an updated review on the current evidence on cataract risk in healthcare workers exposed to IR. METHODS: Published scientific studies on cataract risk in IR exposed healthcare workers were collected through a systematic search of two biomedical databases (MEDLINE and Scopus). Data from included studies was extracted and summarized. Study quality was also assessed. RESULTS: All 21 eligible studies reported an increased prevalence of cataract, especially posterior subcapsular cataract, in IR exposed  HCWs with a higher prevalence in interventional cardiology staff. DISCUSSION: Our review synthesizes the latest evidence to support the hypothesis of a significantly increased risk of occupational cataract in healthcare workers operating MI and exposed to IR, especially in interventional cardiologists. Data also support a dose-response relationship between IR exposure and the prevalence of opacities, especially posterior subcapsular opacities. CONCLUSIONS: Findings highlight the need for effective control measures including appropriate training, adherence to protective procedures, and a constant use of shields and eye personal protective equipment in healthcare workers with optical exposure to IR. Periodic health surveillance programs, possibly including lens evaluation, are also important to monitor cataract risk in these MI operators.


Assuntos
Catarata , Cristalino , Exposição Ocupacional , Lesões por Radiação , Radiação Ionizante , Pessoal de Saúde , Humanos
10.
Yakugaku Zasshi ; 140(9): 1095-1099, 2020.
Artigo em Japonês | MEDLINE | ID: mdl-32879241

RESUMO

The lens of the eye is an avascular and anuclear tissue that serves to focus objects on the retina. Cataract is opacity within the clear lens that changes the transparency and refractive index of the lens causing significant visual impairments. These impairments can severely restrict the ability to carry out daily activities. Cataracts is common among elderly person occurring in more than 80% of patients aged 80 or older. Notably, we have recently identified key compounds that are effective against cataract formation. Presbyopia is also an ocular disease that typically develops in people over the age of 45 while affecting almost 100% of people over the age of 65. Recent research suggests that age-related changes in hydrostatic pressure of the lens controlled by Na/K ATPase contribute to the development of presbyopia. In the lens, Na/K ATPase has been shown to be regulated by transient receptor potential cation channels, vanilloid 1 (TRPV1) and 4, thus suggesting the potential role of TRPV1 and TRPV4 in the development of presbyopia. This review article summarizes data obtained from our laboratory with my colleagues highlighting the critical role of aquaporin 0 (AQP0) in maintaining a healthy lens redox environment, key molecules that delay the onset of cataract in vivo, as well as potential mechanisms of lens hydrostatic pressure control that may be associated with presbyopia.


Assuntos
Aquaporinas/fisiologia , Catarata/tratamento farmacológico , Catarata/etiologia , Desenvolvimento de Medicamentos , Proteínas do Olho/fisiologia , Pressão Hidrostática , Cristalino/metabolismo , Oxirredução , Presbiopia/etiologia , ATPase Trocadora de Sódio-Potássio/metabolismo , ATPase Trocadora de Sódio-Potássio/fisiologia , Canais de Cátion TRPV/fisiologia
11.
Vestn Oftalmol ; 136(4. Vyp. 2): 214-218, 2020.
Artigo em Russo | MEDLINE | ID: mdl-32880142

RESUMO

The article presents a clinical case of a functioning hyaloid artery in a 69-year-old patient. The results of OCT-angiography made it possible to detect the presence of blood flow in the projection of the persistent hyaloid artery (PHA) on the cross-section and en-face images. The vascular bed of PHA spreading along the posterior surface of the lens in the form of separate branches was visualized by slit-lamp biomicroscopy. The uniqueness of this clinical case lies in the low probability of such findings in the elderly. The presence of a developing cataract indicates the need for an individual approach in determining treatment strategies. In our opinion, the consistent use of laser coagulation technologies and laser photodestruction of PHA will minimize the risk of hemophthalmos and tractional retinal detachment during the upcoming cataract surgery.


Assuntos
Extração de Catarata , Catarata , Cristalino , Vítreo Primário Hiperplásico Persistente , Descolamento Retiniano , Adulto , Idoso , Humanos
12.
Leg Med (Tokyo) ; 47: 101787, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32992157

RESUMO

This study was aimed at investigating and comparing exposure dose of workers and the surrounding workers. In addition, worker's exposure was also measure about lens and finger. Four intraoral portable X-ray units were evaluated. The stray radiations were measured using Pitman 37D and ionization chamber (Pitman). MyDosemini (ALOKA) was used for measurement of the finger exposure dose. Without the shield became high in anterior 0.5 m. Comparing the air dose for the four models used in this study showed a high tendency for the two NOMAD models. And using the shields, the images could be taken 4.6 times of the baseline at a maximum and 3.6 times on average. The finger radiation exposure dose was low with both of the NOMAD models, with no significant difference found. By setting the baseline value without a shield, finger radiation exposure when using a shield was lower than the detection limit for the D3000, and was reduced by approximately 94-96% for other three models. All models can photograph around 100 bodies, so it is considered that it is not necessary to switch out the operator considering the operation limit. But even if it does not reach the operation limit, the stochastic effects of radiation exposure can be increased as well as the deterministic effects of the operation limit. The operator and the surrounding workers seek to protect themselves. It is important to perform exposure management that takes into account the stochastic effects to the operator and the surrounding workers.


Assuntos
Exposição Ocupacional/efeitos adversos , Exposição Ocupacional/análise , Doses de Radiação , Radiografia/efeitos adversos , Radiografia/instrumentação , Dedos , Humanos , Cristalino , Exposição Ocupacional/prevenção & controle , Imagens de Fantasmas , Equipamentos de Proteção , Radiografia Dentária
13.
Cell Prolif ; 53(11): e12911, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32985730

RESUMO

OBJECTIVES: Fibrotic cataract, including posterior capsule opacification (PCO) and anterior subcapsular cataract (ASC), renders millions of people visually impaired worldwide. However, the underlying mechanism remains poorly understood. Here, we report a miRNA-based regulatory pathway that controls pathological fibrosis of lens epithelium. MATERIALS AND METHODS: Expression of miR-22-3p and histone deacetylase 6 (HDAC6) in normal and PCO patient samples were measured by qPCR. Human lens epithelial explants were treated with TGF-ß2 in the presence or absence of miR-22-3p mimics or inhibitor. Cell proliferation was determined by MTS assay, and migration was tested by transwell assay. Expression of HDAC6 and EMT-related molecules were analysed by Western blot, qPCR and immunocytochemical experiments. RESULTS: We identify miR-22-3p as a downregulated miRNA targeting HDAC6 in LECs during lens fibrosis and TGF-ß2 treatment. Mechanistically, gain- and loss-of-function experiments in human LECs and lens epithelial explants reveal that miR-22-3p prevents proliferation, migration and TGF-ß2 induced EMT of LECs via targeting HDAC6 and thereby promoting α-tubulin acetylation. Moreover, pharmacological targeting of HDAC6 deacetylase with Tubacin prevents fibrotic opaque formation through increasing α-tubulin acetylation under TGF-ß2 stimulated conditions in both human lens epithelial explants and the whole rat lenses. CONCLUSIONS: These findings suggest that miR-22-3p prevents lens fibrotic progression by targeting HDAC6 thereby promoting α-tubulin acetylation. The 'miR-22-HDAC6-α-tubulin (de)acetylation' signalling axis may be therapeutic targets for the treatment of fibrotic cataract.


Assuntos
Catarata/genética , Desacetilase 6 de Histona/genética , MicroRNAs/genética , Tubulina (Proteína)/metabolismo , Acetilação , Adulto , Catarata/patologia , Proliferação de Células , Células Cultivadas , Regulação para Baixo , Fibrose , Expressão Gênica , Desacetilase 6 de Histona/metabolismo , Humanos , Cristalino/citologia , Cristalino/metabolismo , Cristalino/patologia , Pessoa de Meia-Idade , Fator de Crescimento Transformador beta2/metabolismo
14.
Klin Monbl Augenheilkd ; 237(9): 1079-1086, 2020 Sep.
Artigo em Inglês, Alemão | MEDLINE | ID: mdl-32967032

RESUMO

Iris and lens injuries entail a large spectrum and occur in closed and open globe injuries. Depending on accompanying ocular trauma (e.g. corneal involvement) as well as on the extend of the injuries several different surgical options are available ranging from suturing techniques to special individualized implants. The aim of this article is to present and discuss current treatment options for lens and iris trauma in regards to typical cases.


Assuntos
Traumatismos Oculares/cirurgia , Cristalino/cirurgia , Humanos , Iris/cirurgia , Implante de Lente Intraocular , Técnicas de Sutura
15.
DNA Cell Biol ; 39(11): 1970-1975, 2020 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-32877255

RESUMO

Research showed that lanosterol can decrease protein aggregation in lens and reduce cataract formation. Lanosterol synthase (LSS) and 3-Hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) are the limiting enzymes in the process of synthesis of lanosterol. We demonstrate to investigate the association between functional single-nucleotide polymorphisms (SNPs) of LSS and HMGCR genes and age-related cataract (ARC) risks in Han Chinese population from Jiangsu Eye Study. This is a case-control study. We collected participants' venous blood for DNA genotyping and lens capsule samples for RNA. The SNPs of the genes were assayed with TaqMan RT-PCR genotyping. The quantitative RT-PCR was used to detect the LSS mRNA levels of lens epithelial cells (LECs) in individuals. The chi-square test was used to compare differences between ARC groups and controls of each SNP and to calculate the odds ratio (OR). We found that LSS-rs2968 of ARCs was different from controls (p = 0.018), but the significance was lost after Bonferroni correction (p = 0.072). We then further performed stratification analysis and found that LSS-rs2968 A allele was associated with nuclear type of ARC risk in Chinese population (p = 0.012, OR = 0.68). Consequently, we found that the mRNA expression of LSS was lower in LECs of all subtypes of ARC group than that of control group (p < 0.05). LSS-rs2968 A allele might play a role in the formation and development of nuclear type of ARC risk in Chinese population.


Assuntos
Catarata/genética , Predisposição Genética para Doença , Hidroximetilglutaril-CoA Redutases/genética , Transferases Intramoleculares/genética , Idoso , Envelhecimento , Alelos , Catarata/patologia , Feminino , Regulação da Expressão Gênica/genética , Estudos de Associação Genética , Genótipo , Haplótipos/genética , Humanos , Cristalino/metabolismo , Cristalino/patologia , Masculino , Pessoa de Meia-Idade , Polimorfismo de Nucleotídeo Único/genética
16.
PLoS One ; 15(8): e0238081, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32833997

RESUMO

Cataracts are a major cause of blindness worldwide and commonly occur in individuals over 70 years old. Cataracts can also appear earlier in life due to genetic mutations. The lens proteins, αA- and αB-crystallins, are chaperone proteins that have important roles maintaining protein solubility to prevent cataract formation. Mutations in the CRYAA and CRYAB crystallin genes are associated with autosomal dominant early onset human cataracts. Although studies about the proteomic and genomic changes that occur in cataracts have been reported, metabolomics studies are very limited. Here, we directly investigated cataract metabolism using gas-chromatography-mass spectrometry (GC-MS) to analyze the metabolites in adult Cryaa-R49C and Cryab-R120G knock-in mouse lenses. The most abundant metabolites were myo-inositol, L-(+)-lactic acid, cholesterol, phosphate, glycerol phosphate, palmitic and 9-octadecenoic acids, α-D-mannopyranose, and ß-D-glucopyranose. Cryaa-R49C knock-in mouse lenses had a significant decrease in the number of sugars and minor sterols, which occurred in concert with an increase in lactic acid. Cholesterol composition was unchanged. In contrast, Cryab-R120G knock-in lenses exhibited increased total amino acid content including valine, alanine, serine, leucine, isoleucine, glycine, and aspartic acid. Minor sterols, including cholest-7-en-3-ol and glycerol phosphate were decreased. These studies indicate that lenses from Cryaa-R49C and Cryab-R120G knock-in mice, which are models for human cataracts, have unique amino acid and metabolite profiles.


Assuntos
Catarata/genética , Catarata/metabolismo , Cristalino/metabolismo , Mutação , alfa-Cristalinas/genética , Animais , Modelos Animais de Doenças , Humanos , Metabolômica , Camundongos , Camundongos Endogâmicos C57BL
17.
PLoS One ; 15(8): e0235898, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32833999

RESUMO

Myo/Nog cells were discovered in the chick embryo epiblast. Their expression of MyoD reflects a commitment to the skeletal muscle lineage and capacity to differentiate into myofibroblasts. Release of Noggin by Myo/Nog cells is essential for normal morphogenesis. Myo/Nog cells rapidly respond to wounding in the skin and eyes. In this report, we present evidence suggesting that Myo/Nog cells phagocytose tattoo ink in tissue sections of human skin and engulf cell corpses in cultures of anterior human lens tissue and magnetic beads injected into the anterior chamber of mice in vivo. Myo/Nog cells are distinct from macrophages in the skin and eyes indicated by the absence of labeling with an antibody to ionized calcium binding adaptor molecule 1. In addition to their primary roles as regulators of BMP signaling and progenitors of myofibroblasts, Myo/Nog cells behave as nonprofessional phagocytes defined as cells whose primary functions are unrelated to phagocytosis but are capable of engulfment.


Assuntos
Miofibroblastos/citologia , Fagócitos/citologia , Células-Tronco/citologia , Animais , Proteínas de Transporte/metabolismo , Diferenciação Celular , Células Cultivadas , Embrião de Galinha , Feminino , Humanos , Cristalino/citologia , Cristalino/metabolismo , Masculino , Camundongos , Camundongos Endogâmicos C57BL , Proteína MyoD/metabolismo , Miofibroblastos/metabolismo , Fagócitos/metabolismo , Fagocitose , Coelhos , Pele/citologia , Pele/metabolismo , Células-Tronco/metabolismo
19.
Expert Rev Med Devices ; 17(9): 969-979, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32847426

RESUMO

PURPOSE: To assess the repeatability of several anterior segment parameters obtained with swept-source optical coherence tomography (SS-OCT). METHODS: We measured 5-times consequently several parameters in 69 eyes using the ANTERION SS-OCT. White-to-white (WTW), angle-to-angle (ATA), spur-to-spur (STS), and lens vault distances were measured in the horizontal- and vertical-meridian. Anterior-chamber-angle (ACA), scleral-spur-angle (SSA), angle-opening-distance (AOD), and trabecular-iris-space-area (TISA) were measured at 500 and 750 µm for the superior-, nasal-,inferior-, and temporal-quadrants. Intrasubject standard deviation (Sw),coefficient of variation (CoV), coefficient of repeatability (CoR), and intraclass-correlation-coefficient (ICC) were calculated for each parameter. Bland-Altman analysis was done. RESULTS: We have not found statistically significant differences between repeated measurements (p > 0.05). Repeatability was good for the different parameters evaluated. Sw values in distances and areas were low and ranged from 0.01 to 0.07. CoR values showed a similar pattern being larger for those metrics measuring angles. The same happened with CoV values, being very small for WTW,ATA, and STS distances (0.16-0.57%). ICC values for all parameters analyzed were > 0.97. Bland-Altman plots evidenced the narrow limits of agreement for all parameters. CONCLUSIONS: The ANTERION SS-OCT demonstrated high repeatability measuring different distances, angles, and areas of the anterior segment of the eye.


Assuntos
Câmara Anterior/diagnóstico por imagem , Tomografia de Coerência Óptica/instrumentação , Tomografia de Coerência Óptica/métodos , Algoritmos , Feminino , Humanos , Iris/diagnóstico por imagem , Cristalino , Masculino , Reprodutibilidade dos Testes
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