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1.
Water Sci Technol ; 82(5): 887-904, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33031068

RESUMO

The effectiveness of two Azadirachta indica bark activated carbons (ABAC) for the removal of selected toxic metals from mining wastewater and the attendant challenge of multivariate factors in the process were enhanced through optimization studies. Experimental design was carried out using adsorbent dosage, agitation rate, contact time, grain size, pH and temperature as independent variables. Batch adsorption experiments were conducted using the experimental design result, then the experimental data obtained were optimized using Design-Expert software and the results validated. Optimum values for ABAC-NaOH adsorbent were 1.999 g of adsorbent dosage, 149.73 rpm agitation rate, 119.55 min contact time, 2 mm grain size, pH of 7 and 30 °C temperature; while for ABAC-HCl adsorbent the optimum values were 3.993 g of adsorbent dosage, 150 rpm agitation rate, 120 min contact time, 2 mm grain size, pH of 7.001 and 30 °C temperature. These resulted in 100% removal efficiencies for all the selected toxic metals with standard errors of between 0.02 and 2.72%. So the optimization process is a very useful tool in adsorption studies. It has the merits of being economical, energy and time saving, and is therefore strongly recommended for the biosorption of toxic metals from mining wastewater using Azadirachta indica adsorbent.


Assuntos
Azadirachta , Águas Residuárias , Concentração de Íons de Hidrogênio , Metais , Mineração , Casca de Planta
2.
Shanghai Kou Qiang Yi Xue ; 29(3): 325-328, 2020 Jun.
Artigo em Chinês | MEDLINE | ID: mdl-33043354

RESUMO

PURPOSE: To analyze the effect and long-term success rate of using glass fiber post or metal post in restoration of anterior tooth defect. METHODS: One hundred and fifty cases with anterior tooth defects were chosen after root canal therapy in our hospital. According to different material being chosen, the patients were divided into fiber post group and metal post group with 75 cases in each group. Local gingival sulcus fluid (GCF) levels and alkaline phosphatase (ALP) level in gingival sulcus liquid were measured and compared 4 weeks, 6 months, 1 year, 2 years and 3 years after restoration. Restoration integrity, edge fitness and color matching of two groups were compared after follow-up for 3 years. The data were analyzed with SPSS 19.0 software package. RESULTS: Four weeks, 6 months, and 1 year after restoration, local GCF, ALP levels significantly elevated in both groups. The fiber post group showed more significant elevated levels of GCF and ALP than the metal post group (P<0.05). After 2 and 3 years, the difference between the two groups was not significant. The gingival color matching degrees were significantly better in the glass fiber post group after 1 year compared with that in the metal post group(P<0.05). The success rate of metal post group was significantly higher than that of fiber post group 3 years after restoration(P<0.05). CONCLUSIONS: Fiber post and metal post both have satisfactory restoration result for tooth defect in anterior teeth area. However, the use of precious metal alloy post may reduce the possibility of microleakage between tooth-prosthesis surfaces.


Assuntos
Técnica para Retentor Intrarradicular , Vidro , Humanos , Metais , Tratamento do Canal Radicular
3.
Mar Environ Res ; 160: 104987, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32907725

RESUMO

Ocean acidification alters physiology, acid-base balance and metabolic activity in marine animals. Near future elevated pCO2 conditions could be expected to influence the bioaccumulation of metals, feeding rate and immune parameters in marine mussels. To better understand such impairments, a series of laboratory-controlled experiment was conducted by using a model marine mussel, Mytilus galloprovincialis. The mussels were exposed to three pH conditions according to the projected CO2 emissions in the near future (one ambient: 8.10 and two reduced: 7.80 and 7.50). At first, the bioconcentration of Ag and Cd was studied in both juvenile (2.5 cm) and adult (5.1 cm) mussels by using a highly sensitive radiotracer method (110mAg and 109Cd). The uptake and depuration kinetics were followed 21 and 30 days, respectively. The biokinetic experiments demonstrated that the effect of ocean acidification on bioconcentration was metal-specific and size-specific. The uptake, depuration and tissue distribution of 110mAg were not affected by elevated pCO2 in both juvenile and adult mussels, whereas 109Cd uptake significantly increased with decreasing pH in juveniles but not in adults. Regardless of pH, 110mAg accumulated more efficiently in juvenile mussels than adult mussels. After executing the biokinetic experiment, the perturbation was sustained by using the same mussels and the same experimental set-up, which enabled us to determine filtration rate, haemocyte viability, lysosomal membrane stability, circulating cell-free nucleic acids (ccf-NAs) and protein (ccf-protein) levels. The filtration rate and haemocyte viability gradually decreased by increasing pCO2 level, whereas the lysosomal membrane stability, ccf-NAs, and ccf-protein levels remained unchanged in the mussels exposed to elevated pCO2 for eighty-two days. This study suggests that acidified seawater partially shift metal bioaccumulation, physiological and cellular parameters in the mussel Mytilus galloprovincialis.


Assuntos
Dióxido de Carbono , Metais , Mytilus , Poluentes Químicos da Água , Animais , Bioacumulação , Concentração de Íons de Hidrogênio , Metais/farmacocinética , Mytilus/química , Água do Mar , Poluentes Químicos da Água/farmacocinética
4.
Zhen Ci Yan Jiu ; 45(8): 667-70, 2020 Aug 25.
Artigo em Chinês | MEDLINE | ID: mdl-32869579

RESUMO

OBJECTIVE: To observe the clinical effect of "metal hook fishing" (MHF)-like needling technique combined with Tuina manipulation in the treatment of scapulohumeral periarthritis. METHODS: A total of 72 patients with scapulohumeral periarthritis were randomly divided into MHF-like needling (MHF) and conventional needling groups (n=36 in each group). For patients of the GHF group, the doctor pressed the acupoint with the left index finger, held the disposable acupuncture needles to insert into the Jianqian, Jianyu (LI15), Jianliao (SJ5), Jianzheng (SJ9) and Ashi-point respectively with the right hand, waited for qi-arriving, twirled the needles forward about 3 to 6 times. When a tightened feeling was achieved beneath the needle tip, the doctor held the needle body to slightly shake it 3 to 6 times which mimicked a fish to swallow a hook, kept the situation for a while till relaxation, followed by retaining the needle for 30 min and then withdrew it slowly. Afterwards, the doctor performed Tuina manipulation at the upper limbs for 20 to 30 min. For patients of the conventional needling group, the same acupoints were needled and stimulated with the uniform reducing and reinforcing method for 1 min, followed by retaining the needles for 30 min. Then, massage was performed for 20 to 30 min in the same way as those in the MHF group. The treatment was conducted once daily, 6 times a week for 2 weeks. After the treatment, the visual analogue scale (VAS) was used to assess the pain degree, the range of motion (ROM) scale of the shoulder joint adopted to assess the function, and the activity of daily living (ADL) scale used to assess the patients' daily living ability. The therapeutic effects of the two groups were evaluated after the treatment. RESULTS: After the treatment, the VAS scores of the two groups were notably decreased (P<0.05), being significantly lower in the GHF group than in the conventional needling group (P<0.05). The ROM score and ADL score of the two groups were obviously increased (P<0.05), being significantly higher in the MHF group than in the conventional needling group (P<0.05). Of the 36 cases in the conventional needling and MHF groups, 7 and 17 were cured, 11 and 12 experienced remarkable improvement, 13 and 4 were improved, and 5 and 3 were ineffective, with the total effective rate being 86.1% (31/36) and 91.7% (33/36), respectively. The total effective rate of MHF group was evidently higher than that of the conventional needling group (P<0.05). CONCLUSION: Both MHF and conventional needling is effective in relieving scapulohumeral periarthritis, and the effect of MHF is ob-viously superior to that of conventional needling in relieving pain state and improving function of the affected shoulder joint.


Assuntos
Periartrite , Pontos de Acupuntura , Humanos , Metais , Periartrite/terapia , Dor de Ombro , Resultado do Tratamento
5.
Int J Oral Maxillofac Implants ; 35(5): 982-989, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32991649

RESUMO

PURPOSE: This investigation aimed to evaluate clinical, prosthetic, and patient-based outcomes of a milled bar with polyether ether ketone (PEEK) and metal housings for inclined implants supporting mandibular overdentures. MATERIALS AND METHODS: Eighteen edentulous participants received four implants in the interforaminal area of the mandible (two vertically and two distally inclined), and implants were connected with milled bars. Overdentures were attached to the bars with PEEK female housing (test group). The control group consisted of participants who received milled bar overdentures with conventional metal housings but were case matched to the test group and served as a historical cohort. Clinical parameters (Plaque Index, Gingival Index, pocket depth, and bone loss) were measured at baseline, 6 months, and 12 months. Patient satisfaction (using visual analog scale) and prosthetic complications were recorded after 12 months. RESULTS: The control group showed a significantly higher plaque score and marginal bone resorption compared with the test group. The test group showed higher satisfaction with retention, stability, speech, and esthetics compared with the control group (P < .048). The test group showed a significantly lower incidence of female housing wear (P = .017), plastic clip wear (P < .001), and plastic clip fracture/renewal (P = .049) than the control group. No difference between groups was noted for other clinical, prosthetic, and patient-based outcomes. CONCLUSION: PEEK housing of a milled bar may be a successful alternative to conventional metal housing for inclined implants supporting mandibular overdentures, as it is associated with favorable clinical, prosthetic, and patient-based outcomes after 1 year.


Assuntos
Implantes Dentários/efeitos adversos , Revestimento de Dentadura , Prótese Dentária Fixada por Implante , Estética Dentária , Éter , Éteres , Feminino , Humanos , Cetonas , Mandíbula/cirurgia , Metais
6.
J UOEH ; 42(3): 275-279, 2020.
Artigo em Japonês | MEDLINE | ID: mdl-32879192

RESUMO

The Japan Environment Health and Children's Study (JECS) is an ongoing cohort study designed to evaluate the impact of various environmental factors on children's health. In this study, more than 100,000 pregnant women were recruited in 15 regional centers throughout Japan. Within the University of Occupational and Environmental Health, the departments of Pediatrics, Obstetrics and Gynecology, Environmental Health, and the School of Health Sciences collaborate with the JECS University of Occupational and Environmental Health Subunit Center in advancing research in this study. Several original articles based on JECS and written by our unit members were published in recent years. The aim of this review is to summarize these studies by JECS and University of Occupational and Environmental Health Subunit Center based on the data from JECS. We introduce research articles covering the following categories; environmental health, occupational health, and maternal and child health. Studies found associations between concentrations of metals and maternal health, such as premature birth, placenta previa and placenta accrete, associations between metals and IgE, dietary differences among occupational groups, associations between work-related factors and dietary behaviors, associations between job changes and pregnancy/delivery, mental and physical stress among pregnant women and influence on work, associations between sleep and gestational diabetes, and associations between an ability to push up in the prone position and infant development. This review may promote the development of new research, such as collaborative research projects, including clinical and social medicine, epidemiological studies and laboratory investigations.


Assuntos
Saúde da Criança , Saúde Ambiental , Saúde do Trabalhador , Universidades , Estudos de Coortes , Diabetes Gestacional , Comportamento Alimentar , Feminino , Humanos , Imunoglobulina E , Japão , Metais/metabolismo , Placenta Acreta , Placenta Prévia , Gravidez , Nascimento Prematuro , Trabalho
7.
Mar Pollut Bull ; 159: 111478, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32892916

RESUMO

The spatial distribution, sources and characteristics of marine litter (ML) from 36 locations spread over 12 beaches along the west coast of Qatar have been assessed. A total of 2376 ML items with varying sizes were found with an average abundance of 1.98 items/m2. The order of abundance of ML along the coast was as follows: plastics (71.4%) > metal (9.3%) > glass (5.1%) > paper (4.4%) > fabric (4.0%) > rubber (3.9%) > processed wood (2.0%). Locations in the south and northwest coasts of Qatar had significantly higher concentrations of ML. Surprisingly, nearly 47% of the beached polyethylene terephthalate (PET) bottles were derived from the countries bordering the Arabian/Persian Gulf (Gulf), and most of them were produced in the last 2 years. The plastic materials were drifted by winds and currents to the Qatar coast. Gulf circulation provides evidence to the pathways of ML beached on the Qatar coast.


Assuntos
Monitoramento Ambiental , Resíduos/análise , Praias , Metais , Plásticos , Catar
8.
Nat Commun ; 11(1): 4557, 2020 09 11.
Artigo em Inglês | MEDLINE | ID: mdl-32917908

RESUMO

Why metalloenzymes often show dramatic changes in their catalytic activity when subjected to chemically similar but non-native metal substitutions is a long-standing puzzle. Here, we report on the catalytic roles of metal ions in a model metalloenzyme system, human carbonic anhydrase II (CA II). Through a comparative study on the intermediate states of the zinc-bound native CA II and non-native metal-substituted CA IIs, we demonstrate that the characteristic metal ion coordination geometries (tetrahedral for Zn2+, tetrahedral to octahedral conversion for Co2+, octahedral for Ni2+, and trigonal bipyramidal for Cu2+) directly modulate the catalytic efficacy. In addition, we reveal that the metal ions have a long-range (~10 Å) electrostatic effect on restructuring water network in the active site. Our study provides evidence that the metal ions in metalloenzymes have a crucial impact on the catalytic mechanism beyond their primary chemical properties.


Assuntos
Anidrases Carbônicas/química , Íons/química , Metaloproteínas/química , Metais/química , Sítios de Ligação , Anidrase Carbônica II/química , Anidrase Carbônica II/metabolismo , Anidrases Carbônicas/metabolismo , Catálise , Domínio Catalítico , Cobalto/química , Cobre/química , Cristalografia por Raios X , Humanos , Íons/metabolismo , Cinética , Metaloproteínas/metabolismo , Metais/metabolismo , Modelos Moleculares , Níquel/química , Conformação Proteica , Relação Estrutura-Atividade , Especificidade por Substrato , Zinco/química
9.
Chemosphere ; 254: 126763, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32957263

RESUMO

Epidemiologic studies suggest that circulating metals from the natural environment are linked with cardiometabolic health. However, few studies examined the relationship between multiple metals exposure and metabolic phenotypes, especially in obese individuals. We conducted a cross-sectional study to explore the association between 23 urinary metals and metabolic phenotypes in 1392 overweight and obese individuals (592 males, 800 females, mean age 43.1 ± 9.8 years). Participants were classified as metabolically unhealthy if they had ≥2 of the following metabolic abnormalities: elevated blood pressure, elevated fasting blood glucose, elevated triglycerides, and reduced high-density lipoprotein cholesterol. Odds ratios (ORs) of unhealthy metabolic phenotypes for metal levels categorized into tertiles were assessed using logistic regression models. Five metals (barium, copper, iron, uranium, and zinc) were associated with unhealthy metabolic phenotypes in single-metal models, while in the multiple-metal model, only zinc and zinc-copper ratio remained significant. The ORs (95% CIs) comparing extreme tertiles were 2.57 (1.69, 3.89) for zinc and 1.68 (1.24, 2.27) for zinc-copper ratio after adjustment for confounders (both p-trends were <0.001). The numbers of metabolic abnormalities significantly increased with the levels of zinc and the zinc-copper ratio increased. Similar associations were observed with metabolic syndrome risk. High levels of urinary zinc were positively associated with elevated fasting blood glucose (p-trend < 0.001) and elevated triglycerides (p-trend = 0.003). The results suggest that urinary zinc and zinc-copper ratio are positively associated with increased risk of unhealthy metabolic phenotype. Further prospective studies with a larger sample size are required to verify these findings.


Assuntos
Exposição Ambiental , Metais/urina , Obesidade , Adulto , HDL-Colesterol , Cobre , Estudos Transversais , Feminino , Humanos , Ferro , Modelos Logísticos , Masculino , Síndrome Metabólica , Pessoa de Meia-Idade , Razão de Chances , Sobrepeso , Fenótipo , Estudos Prospectivos , Zinco
10.
Chemosphere ; 254: 126794, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32957267

RESUMO

Present study carried out pot experiments and evaluated effects of single and binary mixture of nanoparticles (exposed via sludge as soil conditioner) on spinach plant. Exposure of Ag2O nanoparticles (NPs) (1 and 10 mg/kg soil-sludge) did not show significant reduction in plant as compared to control. On the other hand, TiO2 NPs (exposed as single and in binary mixture) resulted in significant increase in root length (29% and 37%) and fresh weight (60% and 48%) at highest exposure concentration. Total chlorophyll content decreased for Ag2O and binary mixture (7% and 4%, respectively) and increased for TiO2 (5%) at 10 mg/kg soil-sludge. The toxic interaction between Ag2O and TiO2 NPs was additive at both exposure concentrations. Ag2O NPs had higher tendency of root surface adsorption than TiO2 NPs. Metal content in spinach leaves at highest exposure concentration was Ag: 2.6 ± 0.55 mg/g plant biomass(for Ag2O NPs) and 1.02 ± 0.32 mg/g plant biomass (for Ag2O + TiO2 NPs) and for Ti: 1.12 ± 0.78 (for TiO2 NPs) mg/g plant biomass and 0.58 ± 0.41 mg/g (for Ag2O + TiO2 NPs). The inadvertent ingestion of NPs- contaminated spinach resulted in projected daily intake (DI) of Ag and Ti for different age-mass classes (child to adult) exceeding the oral reference dose for toxicity during oral ingestion. In conclusion, we report no acute toxicity of single and binary mixture of NPs to spinach but significant accumulation of Ag and Ti metals in spinach leaves. There are high chances that ingestion of spinach grown in such environment might lead to human health risks.


Assuntos
Nanopartículas/toxicidade , Poluentes do Solo/toxicidade , Spinacia oleracea/efeitos dos fármacos , Biomassa , Clorofila , Humanos , Nanopartículas Metálicas/toxicidade , Metais/toxicidade , Nanopartículas/análise , Folhas de Planta/química , Esgotos , Solo , Poluentes do Solo/análise , Spinacia oleracea/crescimento & desenvolvimento , Titânio/farmacologia
11.
Bone Joint J ; 102-B(10): 1331-1340, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32993344

RESUMO

AIMS: Stiffness is a common complication after total knee arthroplasty (TKA). Pathogenesis is not understood, treatment options are limited, and diagnosis is challenging. The aim of this study was to investigate if MRI can be used to visualize intra-articular scarring in patients with stiff, painful knee arthroplasties. METHODS: Well-functioning primary TKAs (n = 11), failed non-fibrotic TKAs (n = 5), and patients with a clinical diagnosis of fibrosis1 (n = 8) underwent an MRI scan with advanced metal suppression (Slice Encoding for Metal Artefact Correction, SEMAC) with gadolinium contrast. Fibrotic tissue (low intensity on T1 and T2, low-moderate post-contrast enhancement) was quantified (presence and tissue thickness) in six compartments: supra/infrapatella, medial/lateral gutters, and posterior medial/lateral. RESULTS: Fibrotic tissue was identified in all patients studied. However, tissue was significantly thicker in fibrotic patients (4.4 mm ± 0.2 mm) versus non-fibrotic (2.5 mm ± 0.4 mm) and normal TKAs (1.9 mm ± 0.2 mm, p = < 0.05). Significant (> 4 mm thick) tissue was seen in 26/48 (54%) of compartments examined in the fibrotic group, compared with 17/30 (57%) non-fibrotic, and 10/66 (15%) normal TKAs. Although revision surgery did improve range of movement (ROM) in all fibrotic patients, clinically significant restriction remained post-surgery. CONCLUSION: Stiff TKAs contain intra-articular fibrotic tissue that is identifiable by MRI. Studies should evaluate whether MRI is useful for surgical planning of debridement, and as a non-invasive measurement tool following interventions for stiffness caused by fibrosis. Revision for stiffness can improve ROM, but outcomes are sub-optimal and new treatments are required. Cite this article: Bone Joint J 2020;102-B(10):1331-1340.


Assuntos
Artroplastia do Joelho , Artropatias/diagnóstico por imagem , Artropatias/etiologia , Imagem por Ressonância Magnética/métodos , Complicações Pós-Operatórias/diagnóstico por imagem , Idoso , Idoso de 80 Anos ou mais , Meios de Contraste , Feminino , Fibrose , Humanos , Aumento da Imagem , Masculino , Metais , Pessoa de Meia-Idade
12.
Quintessence Int ; 51(10): 844-852, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32901239

RESUMO

OBJECTIVE: To evaluate the clinical performance of the fiberglass "Figaro" crowns compared to preformed metal crowns (PMCs) in pulpotomized primary molars in children. METHOD AND MATERIALS: This split-mouth controlled randomized clinical study was performed on ten childrens, aged from 4 to 6 years, who needed complete oral rehabilitation under general anesthesia and had one pair or two pairs of their primary molars requiring pulpotomy. After pulp therapy, the teeth were randomly assigned to Figaro or PMC crown groups. Modified United States Public Health Service (USPHS) criteria were used to evaluate crown retention, marginal integration, crown discoloration, secondary caries, and gingival status, at 3 and 6 months. The data were analyzed using the chi-square test with Monte Carlo (MC) correction and McNemar (McN) test at a significance level of .05. RESULTS: Ten patients (three boys, 30%; seven girls, 70%) with a mean age of 4.65 ± 0.709 years participated in this study. At 3 months follow-up, there was no significant difference between the groups, but at 6 months follow-up, Figaro crowns showed significant changes from intact crown to either chipped or large loss, whereas all PMCs were found intact (χ2 = 14.545, P[MC] = 0.000). There was also significant deterioration in Figaro crowns' color after 6 months (χ2[McN] = 8.1, P = .004). CONCLUSION: PMCs were more durable than Figaro crowns, which showed significant deterioration after the 6-month follow-up period.


Assuntos
Coroas , Dente Decíduo , Criança , Pré-Escolar , Feminino , Vidro , Humanos , Masculino , Metais , Dente Molar
13.
J Environ Manage ; 271: 111011, 2020 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-32778295

RESUMO

The use of sandstone as a building material has increased around the world and sandstone quarrying and its wastes pose a potential threat to human health and the environment. More than 50% of the excavated stone is wasted in the form of scrap stone and waste slurry during sandstone quarrying and processing. Sandstone wastes can adversely change native soil properties and should be reused as construction material. The present study aimed to characterise wastes generated during sandstone quarrying and processing, assess their impact on the soil environment and explore their reuse potential. The results of this study show that fine slurry waste has physicochemical properties between sand and sandy loam while the properties of the slurry solids and scrap stone are similar to those of sandstone. Fine stone waste on intrusion into soil reduced the hydraulic conductivity and porosity of soil potentially reducing its productivity. The liquid stone slurry contained metals like Mn, Ni and As at concentrations higher than drinking water standards. These metals may contaminate water sources and affect human health. Therefore, the use of stone wastes as aggregate for road and building construction would be beneficial and would reduce their adverse impacts on the environment.


Assuntos
Materiais de Construção , Solo , Humanos , Metais
14.
Sci Total Environ ; 744: 140841, 2020 Nov 20.
Artigo em Inglês | MEDLINE | ID: mdl-32755776

RESUMO

North Atlantic European grassland systems have a low nutrient use efficiency and high rainfall. This grassland is typically amended with unprocessed slurry, which counteracts soil organic matter depletion and provides essential plant micronutrients but can be mobilised during rainfall events thereby contributing to pathogen, nutrient and metal incidental losses. Co-digesting slurry with waste from food processing mitigates agriculture-associated environmental impacts but may alter microbial, nutrient and metal profiles and their transmission to watercourses, and/or soil persistence, grass yield and uptake. The impact of EU and alternative pasteurisation regimes on transmission potential of these various pollutants is not clearly understood, particularly in pasture-based agricultural systems. This study utilized simulated rainfall (Amsterdam drip-type) at a high intensity indicative of a worst-case scenario of ~11 mm hr-1 applied to plots 1, 2, 15 and 30 days after grassland application of slurry, unpasteurised digestate, pasteurised digestate (two conditions) and untreated controls. Runoff and soil samples were collected and analysed for a suite of potential pollutants including bacteria, nutrients and metals following rainfall simulation. Grass samples were collected for three months following application to assess yield as well as nutrient and metal uptake. For each environmental parameter tested: microbial, nutrient and metal runoff losses; accumulation in soil and uptake in grass, digestate from anaerobic co-digestion of slurry with food processing waste resulted in lower pollution potential than traditional landspreading of slurry without treatment. Reduced microbial runoff from digestate was the most prominent advantage of digestate application. Pasteurisation of the digestate further augmented those environmental benefits, without impacting grass output. Anaerobic co-digestion of slurry is therefore a multi-beneficial circular approach to reducing impacts of livestock production on the environment.


Assuntos
Agricultura , Solo , Animais , Bovinos , Fertilizantes/análise , Esterco , Metais , Nutrientes , Poaceae
15.
Beijing Da Xue Xue Bao Yi Xue Ban ; 52(4): 637-641, 2020 Aug 18.
Artigo em Chinês | MEDLINE | ID: mdl-32773792

RESUMO

OBJECTIVE: To summarize the initial clinical experience and follow-up results of the treatment for ureteroileal anastomotic stricture after radical cystectomy with Allium coated metal ureteral stent. METHODS: From September 2018 to September 2019, 8 patients with ureteroileal anastomotic stricture after radical cystectomy underwent Allium ureteral stent insertion in Peking University People's Hospital and People's Hospital of Daxing District. The preoperative renal pelvis width under ultrasound was collected to evaluate the postoperative hydronephrosis, creatinine and urea nitrogen (BUN) before and after surgery, perioperative infection, and stent-related complications. The serum creatinine and BUN, renal pelvis width under ultrasound, urography and abdominal plain film (KUB) were reviewed at the end of 1, 3, and 6 months and annually postoperatively to observe the stent position and morphology. The long-term stent patency rate, complication rate, renal function and hydronephrosis were followed up and analyzed. The t-test or rank-sum test was used to compare the measurement data of the matched sample from the preoperative to the last follow-up. RESULTS: In the study, 6 cases (7 sides) were ureteral ileal conduit stricture, and 2 cases (3 sides) ureteral orthotopic neobladder stricture. Before surgery, 5 patients underwent long-term indwelling of a single J ureteral stent, with an average indwelling time of (20.6±8.8) months and an average replacement frequency of (3.6±1.3) months/time. The mean width of renal pelvis was (26.5±9.1) mm on preoperative renal ultrasonography. Among them, 6 patients were successfully indwelled with Allium coated metal ureteral stent by retrograde approach, and 2 patients by combination of double-endoscopy and ante-retrograde approach. No surgery-related complications during perioperative period were observed. The mean follow-up period was 9.8 months and Allium stent and ureter remained unobstructed in all the patients at the last follow-up without replacement or removal. Compared with preoperative data, the mean width of renal pelvis and mean blood urea nitrogen (BUN) in the last follow-up period were significantly reduced [(26.5±9.1) mm vs. (13.4±2.5) mm, P=0.008; (11.6±2.3) mmol/L vs. (10.2±2.2) mmol/L, P=0.017], however, there were no significant differences in the average serum creatinine or hemoglobin (P>0.05). Ureteroileal anastomotic re-stricture and other stent-related complications were not observed in all the patients by antegrade urography. CONCLUSION: Allium coated metal ureteral stent could be used for the treatment for ureteroileal anastomotic stricture, which could maintain relatively long-term patency rate and protect renal function. The indwelling time was longer and it could improve quality of life of patients.


Assuntos
Ureter , Obstrução Ureteral , Derivação Urinária , Allium , Anastomose Cirúrgica , Constrição Patológica , Cistectomia , Seguimentos , Humanos , Metais , Qualidade de Vida , Stents , Resultado do Tratamento , Obstrução Ureteral/cirurgia
16.
Ecotoxicol Environ Saf ; 202: 110920, 2020 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-32800255

RESUMO

Advanced glycation end products (AGE) and the receptor for AGE (RAGE) have been found to be pivotal biomarkers to predict the risk of inflammation and oxidative stress. Limited evidence focuses on the influence of occupational exposure to polycyclic aromatic hydrocarbon (PAH) and metal fumes on AGE and RAGE in shipyard welders. Our aim was to determine the relationships among PAH, metal exposure, and inflammatory biomarkers. From September 1 to December 31, 2017, 53 welding workers (exposed group) and 29 office workers (control group) were enrolled in the study. Comprehensive workups included demographic characteristics, laboratory data, AGE, RAGE, Interleukin-6 (IL-6), tumor necrosis factor-α, PAH, and urinary metal concentrations. RAGE levels were measured by flow cytometric analysis. Urinary 1-hydroxypyrene (1-OHP) was used as a biomarker of exposure to PAH. Several metals were elevated in the personal fine particulate matter (PM2.5) samples, including Mn, Fe, V, Co, Zn, and Cu. The exposed group had significantly higher exposure to PM2.5 (p = 0.015), RAGE (p = 0.020), IL-6 (p = 0.008) than the control group. After adjusting for pertinent variables, there was still a significant and positive association between Ni level and AGE (ß = 0.101; 95% CI, 0.031-0.172). Significant relationship between Cr and Cd levels and RAGE was observed (ß = 0.173; 95% CI, 0.017-0.329; ß = 0.084; 95% CI, 0.011-0.157, respectively). Participants with elevated 1-OHP level had higher odds of high RAGE level in the model 1 (OR = 3.466, 95% CI, 1.053-11.412) and model 2 (OR = 3.454, 95% CI, 1.034-11.536). The RAGE expression of participants was significantly associated with IL-6 levels in the fully adjusted model (ß = 0.294; 95% CI, 0.083-0.732). Our findings highlighted that urinary metal levels and PAH were associated with increased AGE and RAGE formation in shipyard workers. Elevated serum RAGE might induce the production of proinflammatory cytokines and trigger ensuing inflammatory cascades.


Assuntos
Poluentes Ocupacionais do Ar/análise , Metais/análise , Exposição Ocupacional/análise , Hidrocarbonetos Policíclicos Aromáticos/análise , Receptor para Produtos Finais de Glicação Avançada/metabolismo , Poluentes Ocupacionais do Ar/toxicidade , Biomarcadores/urina , Gases/análise , Produtos Finais de Glicação Avançada/sangue , Humanos , Inflamação , Masculino , Metais/toxicidade , Estresse Oxidativo , Material Particulado/análise , Hidrocarbonetos Policíclicos Aromáticos/toxicidade , Fator de Necrose Tumoral alfa , Soldagem
17.
Bone Joint J ; 102-B(8): 1025-1032, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-32731836

RESUMO

AIMS: Total knee arthroplasty is an established treatment for knee osteoarthritis with excellent long-term results, but there remains controversy about the role of uncemented prostheses. We present the long-term results of a randomized trial comparing an uncemented tantalum metal tibial component with a conventional cemented component of the same implant design. METHODS: Patients under the age of 70 years with symptomatic osteoarthritis of the knee were randomized to receive either an uncemented tantalum metal tibial monoblock component or a standard cemented modular component. The mean age at time of recruitment to the study was 63 years (50 to 70), 46 (51.1%) knees were in male patients, and the mean body mass index was 30.4 kg/m2 (21 to 36). The same cruciate retaining total knee system was used in both groups. All patients received an uncemented femoral component and no patients had their patella resurfaced. Patient outcomes were assessed preoperatively and postoperatively using the modified Oxford Knee Score, Knee Society Score, and 12-Item Short-Form Health Survey questionnaire (SF-12) score. Radiographs were analyzed using the American Knee Society Radiograph Evaluation score. Operative complications, reoperations, or revision surgery were recorded. A total of 90 knees were randomized and at last review 77 knees were assessed. In all, 11 patients had died and two were lost to follow-up. RESULTS: At final review all patients were between 11 and 15 years following surgery. In total, 41 of the knees were cemented and 36 uncemented. There were no revisions in the cemented group and one revision in the uncemented group for fracture. The uncemented group reported better outcomes with both statistically and clinically significant (p = 0.001) improvements in knee-specific Oxford and Knee Society scores compared with the cemented group. The global SF-12 scores demonstrated no statistical difference (p = 0.812). Uncemented knees had better radiological analysis compared with the cemented group (p < 0.001). CONCLUSION: Use of an uncemented trabecular metal tibial implant can afford better long-term clinical outcomes when compared to cemented tibial components of a matched design. However, both have excellent survivorship up to 15 years after implantation. Cite this article: Bone Joint J 2020;102-B(8):1025-1032.


Assuntos
Artroplastia do Joelho/efeitos adversos , Artroplastia do Joelho/métodos , Cimentos para Ossos/farmacologia , Osteoartrite do Joelho/cirurgia , Desenho de Prótese/métodos , Falha de Prótese , Idoso , Feminino , Seguimentos , Humanos , Masculino , Metais/uso terapêutico , Pessoa de Meia-Idade , Osteoartrite do Joelho/diagnóstico por imagem , Reoperação/estatística & dados numéricos , Medição de Risco , Método Simples-Cego , Tantálio/uso terapêutico , Tíbia/cirurgia , Fatores de Tempo , Resultado do Tratamento
18.
Mar Pollut Bull ; 159: 111509, 2020 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-32763562

RESUMO

Tropical coastal areas are increasingly exposed to temperature extremes from marine heatwaves and contaminants from anthropogenic activities. The interactive effects of these environmental changes on marine life are understudied. We investigated the direct and cross-generational effects of copper (Cu) on F0 and F1 generations of the common tropical copepod Pseudodiaptomus annandalei under extreme temperatures (30 and 34 °C). In F0, Cu exposure reduced survival and nauplii production; these patterns were more pronounced at 34 °C and in females. F0 Copepods produced more faecal pellets at 34 °C than 30 °C, indicating a higher energetic demand. In F1, the number of F1 adults was lower in CuF0 and at 34 °C. Cu-exposed F0 produced larger adult F1, while exposure to 34 °C resulted in smaller adult F1. Our results show that tropical copepods are highly vulnerable to the interactive effects of contaminants and extreme temperatures.


Assuntos
Copépodes , Poluentes Químicos da Água , Animais , Cobre , Feminino , Metais , Temperatura
20.
J Environ Manage ; 274: 111193, 2020 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-32810680

RESUMO

Composting represents a suitable and cheap method for handling and processing seaweeds accumulated on the coast. Within this framework, two seaweed composts were prepared, one with Undaria pinnatifida accumulated in spring-summer and other with a mixture of seaweeds accumulated in autumn-winter, both from Central Patagonian beaches. The effect of these two composts was evaluated experimentally as an amendment for the growth of Sarcocornia perennis (chickenclaws), a plant species dominating Patagonian salt marshes. Both composts were applied at 75, 50, and 25% doses with perlite. The analysis of the compost properties (phytotoxicity test, C/N, electrical conductivity, pH, and metal content) allowed characterizing both composts as matures and stables. The growth results showed that both composts allow the growth of S. perennis in all doses tested; however, Undaria compost was better in the stimulation of vegetative growth when applied in dose 50%, followed by 75% of both composts. For these reasons, both composts from seaweed waste accumulated on Patagonian coasts could be used in the growth of S. perennis and potentially other plant species, giving value to the seaweeds that currently are considered a waste that disturb these coasts and are discarded without use.


Assuntos
Chenopodiaceae , Compostagem , Alga Marinha , Metais , Solo , Verduras
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