Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 57.695
Sensors (Basel) ; 21(10)2021 May 20.
Artigo em Inglês | MEDLINE | ID: mdl-34065366


Sensorless and sensor-based upper limb exoskeletons that enhance or support daily motor function are limited for children. This review presents the different needs in pediatrics and the latest trends when developing an upper limb exoskeleton and discusses future prospects to improve accessibility. First, the principal diagnoses in pediatrics and their respective challenge are presented. A total of 14 upper limb exoskeletons aimed for pediatric use were identified in the literature. The exoskeletons were then classified as sensorless or sensor-based, and categorized with respect to the application domain, the motorization solution, the targeted population(s), and the supported movement(s). The relative absence of upper limb exoskeleton in pediatrics is mainly due to the additional complexity required in order to adapt to children's growth and answer their specific needs and usage. This review highlights that research should focus on sensor-based exoskeletons, which would benefit the majority of children by allowing easier adjustment to the children's needs. Sensor-based exoskeletons are often the best solution for children to improve their participation in activities of daily living and limit cognitive, social, and motor impairments during their development.

Exoesqueleto Energizado , Pediatria , Atividades Cotidianas , Criança , Humanos , Movimento , Extremidade Superior
Hosp Pediatr ; 11(6): 636-649, 2021 06.
Artigo em Inglês | MEDLINE | ID: mdl-34021029


CONTEXT: Pediatric family-centered rounds (FCRs) have been shown to have benefits in staff satisfaction, teaching, and rounding efficiency, but no systematic review has been conducted to explicitly examine the humanistic impact of FCRs. OBJECTIVE: The objective with this review is to determine if FCRs promote the core values of humanism in medicine by answering the question, "Do FCRs promote humanistic pediatric care?" DATA SOURCES: Using Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, we conducted a search of PubMed, Web of Science, Cumulative Index of Nursing and Allied Health Literature, and Dissertation Abstracts for peer-reviewed pediatric studies through January 1, 2020. We used search terms including FCRs, communication, humanism, and the specific descriptors in the Gold Foundation's definition of humanism. STUDY SELECTION: Abstracts (n = 1003) were assessed for 5 primary outcomes: empathy, enhanced communication, partnership, respect, and satisfaction and service. We evaluated 158 full-text articles for inclusion, reconciling discrepancies through an iterative process. DATA EXTRACTION: Data abstraction, thematic analysis, and conceptual synthesis were conducted on 29 studies. RESULTS: Pediatric family-centered rounds (FCRs) improved humanistic outcomes within all 5 identified themes. Not all studies revealed improvement within every category. The humanistic benefits of FCRs are enhanced through interventions targeted toward provider-family barriers, such as health literacy. Patients with limited English proficiency or disabilities or who were receiving intensive care gained additional benefits. CONCLUSIONS: Pediatric FCRs promote humanistic outcomes including increased empathy, partnership, respect, service, and communication. Limitations included difficulty in defining humanism, variable implementation, and inconsistent reporting of humanistic outcomes. Future efforts should include highlighting FCR's humanistic benefits, universal implementation, and adapting FCRs to pandemics such as coronavirus disease 2019.

Atitude do Pessoal de Saúde , Humanismo , Pediatria/métodos , Relações Profissional-Família , Visitas com Preceptor/métodos , Criança , Criança Hospitalizada , Comunicação , Empatia , Humanos
Med J Malaysia ; 76(3): 284-290, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-34031324


INTRODUCTION: The Coronavirus Disease 2019 (COVID-19) has dramatically affected global healthcare systems. We aimed to determine the response of our paediatric surgical fraternity to a disease that overwhelmingly affects adults. MATERIALS AND METHODS: We conducted a cross-sectional questionnaire-based study over 6 weeks during a federally mandated lockdown. Using snowball sampling, we recruited paediatric surgeons, trainees and medical officers from paediatric surgical units in Malaysia. The anonymous online questionnaire covered sociodemographic information, changes in patient care, redeployment, concerns regarding family members, and impact on training. Mental well-being was assessed using the Depression, Anxiety and Stress Scale (DASS-21). Kruskal-Wallis, ANOVA and multiple regression analysis was used, with significance level 0.05. RESULTS: Of the 129 eligible participants, 100(77%) responded. Junior doctors had clinically higher levels of depression, anxiety, and stress. Age <30 years was significantly associated with anxiety. Junior doctors believed that redeployment led to loss of surgical skills (p<0.001) and trainees felt that clinical application of knowledge had reduced (p<0.020). CONCLUSION: Specific to our paediatric surgical community, this study highlights areas of concern, particularly among junior doctors. It is likely that recurrent cycles of the pandemic will occur soon. These issues must be addressed to preserve the mental and emotional well-being of all health care workers.

Transtornos Mentais/etiologia , Doenças Profissionais/etiologia , Pediatras/psicologia , Pediatria/tendências , Especialidades Cirúrgicas/tendências , Cirurgiões/psicologia , Adulto , Ansiedade/diagnóstico , Ansiedade/epidemiologia , Ansiedade/etiologia , Atitude do Pessoal de Saúde , /prevenção & controle , Criança , Estudos Transversais , Depressão/diagnóstico , Depressão/epidemiologia , Depressão/etiologia , Feminino , Humanos , Malásia/epidemiologia , Masculino , Transtornos Mentais/diagnóstico , Transtornos Mentais/epidemiologia , Saúde Mental , Doenças Profissionais/diagnóstico , Doenças Profissionais/epidemiologia , Saúde do Trabalhador , Estresse Ocupacional/diagnóstico , Estresse Ocupacional/epidemiologia , Estresse Ocupacional/etiologia , Pandemias , Pediatras/educação , Pediatras/tendências , Pediatria/educação , Padrões de Prática Médica , Escalas de Graduação Psiquiátrica , Especialidades Cirúrgicas/educação , Cirurgiões/educação , Cirurgiões/tendências , Inquéritos e Questionários
Adv Exp Med Biol ; 1318: 197-208, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33973180


Viral respiratory tract infections are prevalent in children. They have substantial effects on childhood morbidity throughout the world, especially in developing countries. In this chapter, we describe the preliminary characteristics of pediatric COVID-19 and discover that severe and critical disease in children is rare. Many children remain asymptomatic. The reason why severity increases with progressing age and largely spares children is not yet known. In the search for possible explanations, we explore key differences between the pediatric and adult immune responses to new pathogens, and in host factors, such as ACE2 abundance.

Pediatria , Adulto , Criança , Humanos , Peptidil Dipeptidase A
Anticancer Res ; 41(5): 2591-2596, 2021 May.
Artigo em Inglês | MEDLINE | ID: mdl-33952488


BACKGROUND/AIM: Tacrolimus is an essential immunosuppressant for successful allogeneic haematopoietic stem cell transplantation (Allo-HSCT). This study aimed to examine the change in the blood concentration of tacrolimus during switching from intravenous to oral administration in allo-HSCT for paediatric cancer to predict the optimal dosage. PATIENTS AND METHODS: We retrospectively examined the medical records of 63 patients who received allo-HSCT and were administered tacrolimus. To compare bioavailability among different dose ranges, the blood concentration was divided by the dose (C/D). RESULTS: Thirty-nine patients (age range=children 1-15 years, adults 17-67 years) were switched to oral administration of tacrolimus. The C/D after switching was significantly lower in children than in adults (p=0.039). There was a strong positive correlation between age and C/D in children, whereas no correlation was observed in adults. CONCLUSION: In paediatric cancer patients, switching tacrolimus administration route may result in reduced blood concentrations. This tendency is more prominent in younger children.

Administração Intravenosa/métodos , Administração Oral , Neoplasias/tratamento farmacológico , Tacrolimo/administração & dosagem , Adolescente , Adulto , Idoso , Fenômenos Fisiológicos Sanguíneos/efeitos dos fármacos , Criança , Pré-Escolar , Feminino , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Neoplasias/sangue , Neoplasias/patologia , Pediatria , Tacrolimo/efeitos adversos , Adulto Jovem
BMC Surg ; 21(1): 240, 2021 May 11.
Artigo em Inglês | MEDLINE | ID: mdl-33975594


BACKGROUND: We aimed to evaluate the impact of COVID-19 pandemic on pediatric transplant outcomes and determine whether to continue pediatric transplant activity or not, and how policies intended our center has been effective in preventing COVID-19 among organ transplant recipients. METHODS: We conducted a single-center, retrospective, cohort study of hospitalized pediatrics after organ transplantation at Shiraz transplant center since March to August 2020. All liver and kidney transplanted children were included the study and their laboratory and clinical related COVID-19 characteristics were followed up till 3 months after transplantation during hospitalization period and then weekly by the transplant committee. RESULTS: Fifty-one patients underwent transplantation including 11 kidney and 40 liver recipients. The mean age of the pediatric cases was 6.72 ± 5.47 years. A total of 11 patients died due to post-transplant complications, while none of the patients presented any sign or symptoms in favor of COVID-19 in the hospital course after transplantation. Six transplants including 2 kidney and 4 liver were canceled when positive PCR tests were detected in their donors before the surgery. In the 3 months of follow up, two patients presented with symptoms including high grade fever, malaise, rhinorrhea, and GI symptoms. Both patients had two negative PCR, and no radiologic or laboratory results regarding COVID-19 were also detected. One had positive influenza PCR, while the second one had a positive serologic test for EBV; CT, computed tomography CONCLUSION: Transplant programs could continue their activities during the COVID-19 pandemic with specific case selection, accurate screening methods and following protective protocols.

Transplante de Rim , Pediatria , Criança , Pré-Escolar , Estudos de Coortes , Seguimentos , Humanos , Lactente , Irã (Geográfico)/epidemiologia , Fígado , Pandemias , Estudos Retrospectivos , Centros de Atenção Terciária
Recent Results Cancer Res ; 218: 149-173, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34019168


The care of pediatric cancer patients is a vast departure from cancer care of adults. While the available treatment modalities-chemotherapy, radiation, and surgery-are the same, the diseases, care-delivery, and outcomes differ greatly. And just as 'children are not just little adults,' pediatric bioethics occupies a distinct place within the broader field of bioethics. In this chapter, we will begin with an introduction to fundamental principles and frameworks for understanding ethical issues in pediatrics, highlighting the triadic nature of medical decision-making between a physician, the child-patient, and the child's parent as the surrogate decision-maker. We will then delve into further details of how these principles and frameworks shape the care of children with cancer, examining specific ethical challenges commonly encountered by pediatric oncologists. We will traverse this landscape by examining issues involving (a) informed consent; (b) research involving children; (c) end of life; (d) genetic and genomic testing; and (e) professionalism. We also examine ethical challenges in clinical research, in children and more broadly. While not an exhaustive exploration of the myriad ethical issues one might encounter in pediatric cancer medicine and clinical trials, this chapter provides readers with a foundation for further reading.

Neoplasias , Pediatria , Adulto , Criança , Tomada de Decisões , Humanos , Consentimento Livre e Esclarecido , Oncologia , Neoplasias/terapia
Pediatr Radiol ; 51(6): 1076-1078, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-33999248


It seems paradoxical that facts, data and science are still considered controversial despite the harrowing death of a multitude of people from coronavirus disease 2019 (COVID-19), an unparalleled health care crisis of our lifetime. In addition, while scientists are desperately attempting to produce a vaccine for COVID-19, a large segment of the populace still believes in conspiracies related to vaccines. Therefore, it is not surprising that the diagnosis of abusive head trauma (AHT) faces similar challenges - the difference being that AHT challenges are mostly in the realms of law courts rather than actual clinical management of these infants. Against this backdrop, the Child Abuse Imaging Committee of the Society for Pediatric Radiology (SPR) collaborated with other leading experts to develop the consensus statement on AHT. This consensus statement has had a significant impact since its publication. It is now endorsed by 17 multinational, multidisciplinary organizations. The consensus statement has helped educate the diverse stakeholders of AHT and has helped further our understanding of AHT and the issues related to it. This could serve as the template for developing future consensus documents.

Maus-Tratos Infantis/diagnóstico , Consenso , Traumatismos Craniocerebrais/diagnóstico por imagem , Diagnóstico por Imagem/métodos , Criança , Pré-Escolar , Humanos , Lactente , Pediatria , Radiologia , Sociedades Médicas
Med Sci Monit ; 27: e930214, 2021 May 14.
Artigo em Inglês | MEDLINE | ID: mdl-33986238


BACKGROUND Regulation disorders are already apparent in infancy. The For Healthy Offspring Project was the first Hungarian study aimed at building an effective model for screening and examining the prevalence and complex (medical and psychosocial) background of classic behavior regulation disorders (excessive crying, feeding, and sleep problems) in infancy. MATERIAL AND METHODS Data were collected from families of 0- to 3-year-old children in a pediatric hospital and its neighboring areas through questionnaires, medical examinations, and individual and small-group consultations. RESULTS In the questionnaire study about their children's behavior (n=1133), 15% of mothers reported excessive crying, 16% reported feeding problems, and 10% reported sleep problems. In a subsample (n=619) in which medical examinations were also conducted, the prevalence of medical diagnoses was 15.0% for excessive crying, 15.2% for sleep disorders, 10.3% for breastfeeding difficulties, and 14.8% for feeding disorders. Children who were referred to the screening program (n=183) had significantly more behavior regulation disorders than the other children in our study. Regulation disorders were found to be comorbid with other health conditions in some cases. CONCLUSIONS We developed a complex model to screen for regulatory problems in early childhood. This study adds more information about the relationship between regulation problems and other health conditions. The general incidence (5-15%) of early childhood regulation disorders in other countries is likely similar to that found in Hungary. In order to effectively recognize early regulation disorders, diagnostic instruments widely used in the international field should be adapted in general Hungarian pediatric care.

Transtornos da Alimentação e da Ingestão de Alimentos/fisiopatologia , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Transtornos do Sono-Vigília/fisiopatologia , Transtornos do Sono-Vigília/psicologia , Adulto , Aleitamento Materno/psicologia , Pré-Escolar , Choro/fisiologia , Choro/psicologia , Ingestão de Alimentos/fisiologia , Ingestão de Alimentos/psicologia , Feminino , Humanos , Hungria , Lactente , Recém-Nascido , Masculino , Mães/psicologia , Poder Familiar/psicologia , Pediatria , Prevalência , Inquéritos e Questionários
West Afr J Med ; 38(5): 415-419, 2021 May 29.
Artigo em Inglês | MEDLINE | ID: mdl-34051070


The Faculty of Paediatrics of the West African College of Physicians has been using the long case as a major clinical examination for Membership candidates since the early 1980s. Many training institutions also retain the long case examination. Over the years, the Faculty made far-reaching changes in this method of examination geared towards the improvement of its performance indices of reliability, validity and fairness. The current paper traces the modifications that have taken place so far including the use of a structured, weighted grading format. It also discusses the need for further modifications including observation of the candidate during the "clerking" period and the practicality of video recording. Use of formats like that of the West African College is recommended for institutions still using the long case. Each institution should weigh the practicability of specific suggested modifications in the light of its circumstances.

Pediatria , Médicos , Criança , Humanos , Reprodutibilidade dos Testes
Rev. ecuat. pediatr ; 22(1): 1-7, Abril 30, 2021.
Artigo em Inglês | LILACS | ID: biblio-1222349


Introducción: Las Infecciones asociadas a la atención de la salud (IAAS) son procesos infecciosos transmisibles que se presentan después de 48 horas de hospitalización sin estar presentes en el momento de ingreso. El objetivo del presente estudio fue establecer la prevalencia y sus factores asociados. Métodos: El presente estudio de tipo transversal y analítico se realizó en el área de Pediatría y Unidad de Cuidados Intensivos Pediátricos del Hospital Vicente Corral Moscoso de Cuenca, Ecuador en el período Mayo 2018-Octubre 2019. Se incluyeron con una muestra probabilística niños de 29 días de edad hasta menores de 16 años. Las variables observadas fueron la presencia de IAAS, edad, estado nutricional, diagnóstico de ingreso, días de hospitalización, uso de ventilación mecánica, uso de catéteres, sitio de internación, germen aislado y resistencia antibiótica. Se utiliza estadística descriptiva y razón de prevalencia (RP). Resultados: Fueron 385 casos, 212 hombres (55.1%). La edad más prevalente: lactantes 31.4%. La prevalencia de IAAS fue del 13.5% (IC95% 13.33-13.68%). La principal IAAS fue la sepsis (40.4%), seguida por la neumonía (36.5%). La edad <24 meses RP 2.55 (IC95% 1.5-4.2, P<0.001), Desnutrición RP 4.07 (IC95% 2.5-6.6, P=<0.001), hospitalización >14 días RP 32.0 (IC95% 16.6-61.6 P<0.001), uso de catéter venoso central RP 16.6 (IC95% 8.7-32.2, P<0.001). Conclusiones: Existe una prevalencia de IASS mayor al 10% y se asocia con factores que condiciona mayor permanencia hospitalaria, desnutrición y uso de dispositivos invasivos.

Introduction: Infections associated with health care (HAI) are communicable infectious processes that occur after 48 hours of hospitalization without being present at the time of admission. The objective of the present study was to establish the prevalence and its associated factors. Methods: The present cross-sectional and analytical study was carried out in the area of Pediatrics and the Pediatric Intensive Care Unit of the Vicente Corral Moscoso Hospital in Cuenca, Ecuador in the period May 2018-October 2019. Children of 29 days of age to under 16 years were included with a probabilistic sample. The variables observed were the presence of HAI, age, nutritional status, admission diagnosis, days of hospitalization, use of mechanical ventilation, use of catheters, hospitalization site, isolated germ, and antibiotic resistance. Descriptive statistics and prevalence ratio (PR) are used. Results: There were 385 cases, 212 men (55.1%). The most prevalent age: infants 31.4%. The prevalence of HAI was 13.5% (95% CI 13.33-13.68%). The main HAI was sepsis (40.4%), followed by pneumonia (36.5%). Age <24 months PR 2.55 (95% CI 1.5-4.2, P <0.001), Malnutrition PR 4.07 (95% CI 2.5-6.6, P = <0.001), hospitalization> 14 days PR 32.0 (95% CI 16.6-61.6 P <0.001), so from central venous catheter RP 16.6 (95% CI 8.7-32.2, P <0.001). Conclusions: There is a prevalence of IASS greater than 10% and it is associated with factors that condition longer hospital stays, malnutrition and the use of invasive devices.

Pediatria , Infecção Hospitalar , Unidades de Terapia Intensiva , Fatores de Risco , Desnutrição
Arch. argent. pediatr ; 119(2): 83-90, abril 2021. tab
Artigo em Inglês, Espanhol | LILACS, BINACIS | ID: biblio-1151230


Introducción. Los pediatras, cirujanos y subespecialistas, como urólogos y nefrólogos pediátricos, participan en el diagnóstico y tratamiento de la nefrolitiasis pediátrica. El objetivo fue determinar los enfoques de distintas disciplinas y evaluar las diferencias en sus protocolos de diagnóstico y tratamiento habituales.Población y métodos. Cuestionario administrado a participantes de sesiones sobre nefrolitiasis en congresos nacionales en 2017 para evaluar las rutinas de diagnóstico y tratamiento de la nefrolitiasis entre distintas especialidades (cirujanos y pediatras) y subespecialidades (nefrólogos pediátricos y urólogos pediátricos).Resultados. Se analizaron 324 cuestionarios de 88 pediatras, 121 urólogos, 23 cirujanos pediátricos, 54 nefrólogos pediátricos y 38 urólogos pediátricos. Ambos grupos coincidieron en la necesidad de una evaluación metabólica. Para los cálculos ureterales distales ≥6 mm, los cirujanos preferían una ureteroscopía; los pediatras, una litotricia por ondas de choque (LOC) (p < 0,001); y los subespecialistas, una ureteroscopía (p = 0,636). Para los cálculos en la parte inferior de los cálices renales < 1 cm, los cirujanos y los subespecialistas preferían la LOC y los pediatras, la hidratación (p < 0,001; p = 0,371). Para los cálculos de entre 1,1 cm y 2 cm, los cirujanos preferían la cirugía retrógrada intrarrenal (CRIR) y la LOC, y los pediatras, la LOC (p = 0,001). Para los cálculos más grandes, los cirujanos y subespecialistas preferían la nefrolitotomía percutánea (NLP) y los pediatras, la LOC (p = 0,458; p = 0,001).Conclusión. Existen diferencias entre las disciplinas que participan activamente en el diagnóstico y tratamiento de la nefrolitiasis

Introduction. Pediatricians, surgeons and subspecialties as pediatric urology and nephrology are involved in the diagnosis and treatment of pediatric renal stone disease (RSD). The aim of this study was to determine diagnostic and treatment approaches, of different disciplines, and to assess differences in their routine diagnostic and treatment protocols.Population and methods. A questionnaire was designed and administered to the participants of the RSD sessions in national congresses of all disciplines in 2017 to evaluate the diagnostic and treatment routines of specialties (surgeons and pediatricians) and subspecialties (pediatric nephrologists and pediatric urologists) for RSD. Results. A total, of 324 questionnaires were analyzed, from 88 pediatricians (27 %), 121 urologists (37 %), 23 pediatric surgeons (7 %), 54 pediatric nephrologists (17 %), and 38 pediatric urologists (12 %). Both groups agreed on the necessity of metabolic evaluation. For distal ureter stones that were ≥ 6 mm; surgeons preferred ureteroscopy (URS), pediatricians preferred shock wave lithotripsy (SWL) (p < 0.001) and subspecialties preferred URS for the treatment (p = 0.636). For lower calix stones less than 1 cm surgeons and subspecialists preferred SWL, while pediatricians preferred hydration (p < 0.001, p = 0.371). For the stone between 1.1 and 2 cm, surgeons preferred intrarenal surgery (RIRS) and SWL, pediatricians preferred SWL (p = 0.001). For larger stones, surgeons and subspecialists preferred percutaneous nephrolithotomy (PCNL), and pediatricians preferred SWL (p = 0.458 p = 0.001). Pediatric urologist chose low-dose computerized tomography as a diagnostic radiologic evaluation (p = 0.029).Conclusion. There are differences between the disciplines who take an active role in diagnosis and treatment of RSD.

Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Nefrolitíase/terapia , Pediatria , Turquia , Inquéritos e Questionários , Ureteroscopia , Nefrolitíase/diagnóstico
Arch. argent. pediatr ; 119(2): e117-e120, abril 2021. tab
Artigo em Inglês, Espanhol | LILACS, BINACIS | ID: biblio-1151875


La infección crónica con el virus B de la hepatitis es una de las enfermedades de mayor prevalencia mundial. Puede evolucionar a la cirrosis y carcinoma hepatocelular. La detección temprana, evitar la utilización de drogas intravenosas, la educación sexual y la vacunación son fundamentales para la prevención. La infección neonatal y durante el primer año de vida evoluciona hacia la cronicidad en más del 90 % de los niños. La transmisión vertical, de una madre con virus B de la hepatitis al recién nacido, es, actualmente, la forma más frecuente de infección. Su detección y la administración de inmunoglobulinas y vacuna disminuyen esta vía de infección. El tratamiento antiviral puede acelerar en dos o tres años el pasaje de la fase activa a la inactiva de la infección, sin influir en el proceso hacia la recuperación. El tratamiento oportuno de algunos casos elegidos puede evitar la progresión de la enfermedad

Chronic hepatitis B virus infection is one of the most prevalent diseases worldwide. It may progress to cirrhosis and hepatocellular carcinoma. An early detection, not using intravenous drugs, sex education, and immunization are critical for prevention. An infection in the neonatal period and in the first year of life becomes chronic in more than 90 % of children. Vertical transmission from a mother with hepatitis B virus to the newborn infant is currently the most common mode of transmission. Detection, immunoglobulin administration, and immunization help to reduce it. Antiviral therapy may accelerate the transition from the active to the inactive phase of infection by two or three years, without affecting the recovery process. A timely treatment of some selected cases may prevent hepatitis B progression.

Humanos , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adolescente , Hepatite B Crônica/terapia , Pediatria , Transmissão de Doença Infecciosa , Progressão da Doença , Hepatite B Crônica
Arch. argent. pediatr ; 119(2): e121-e128, abril 2021. tab
Artigo em Inglês, Espanhol | LILACS, BINACIS | ID: biblio-1151878


Dados los avances sobre mucopolisacaridosis Icon posterioridad al consenso publicado en la Argentina por un grupo de expertos en 2008, se revisan recomendaciones respecto a estudios genéticos, seguimiento cardiológico, cuidado de la vía aérea, alertas sobre aspectos auditivos, de la patología espinal y neurológica. Se hace revisión de la terapéutica actual y se enfatiza en la necesidad de un diagnóstico y tratamiento precoces, así como de un seguimiento interdisciplinario

Considering the advances made on mucopolysaccharidosis type I after the consensus study published by a group of experts in Argentina in 2008, recommendations about genetic testing, cardiological follow-up, airway care, hearing impairment detection, spinal and neurological conditions, as well as current treatments, were reviewed. Emphasis was placed on the need for early diagnosis and treatment, as well as an interdisciplinary follow-up

Humanos , Mucopolissacaridose I/diagnóstico , Mucopolissacaridose I/terapia , Pediatria , Mucopolissacaridose I/etiologia , Mucopolissacaridose I/genética , Assistência ao Convalescente
Arch. argent. pediatr ; 119(2): 131-138, abril 2021. ilus
Artigo em Espanhol | LILACS, BINACIS | ID: biblio-1152134


A 11 años del primer brote de dengue en Buenos Aires, el 20 de marzo de 2020, mientras se iniciaba la cuarentena obligatoria por COVID-19, dengue pasó a ser la causa más común de consulta por fiebre. La nueva ola de casos de dengue ya se encontraba entre las predicciones de la Organización Panamericana de la Salud en función del aumento en la región de las Américas que se venía presentando desde el año anterior. La llegada del SARS-CoV-2 a principios de marzo, sumada al brote de dengue que ya estaba en curso, resultó en un nuevo desafío para el sistema de salud, mientras comenzaba un paradigma con planes de adaptación a la nueva infección pandémica en el país. La superposición de infecciones con potencial epidémico, como dengue, recuerda la importancia de no desatender otras enfermedades endémicas, emergentes y reemergentes a la sombra del nuevo fenómeno epidemiológico

Eleven years after the first dengue outbreak in Buenos Aires, on March 20, 2020, while the mandatory quarantine for COVID-19 began dengue became the most common cause of fever consultation. The new wave of dengue cases was already among the predictions of the Pan American Health Organization based on the increase in the region of the Americas that had been occurring since the previous year. The arrival of SARS-CoV-2 at the beginning of March, added to the dengue outbreak that was already underway, made a new challenge for the health system while a new paradigm was initiated with adaptation plans to the new pandemic infection in the country. The overlapping of infections with epidemic potential such as dengue recalls the importance of not neglecting other endemic, emerging and re-emerging diseases in the shadow of the new epidemiological phenomenon.

Humanos , Dengue/epidemiologia , Pediatria , Arbovírus , Argentina/epidemiologia , Infecções por Coronavirus , Aedes , Coinfecção