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1.
BMJ Open ; 11(9): e047858, 2021 09 06.
Artigo em Inglês | MEDLINE | ID: mdl-34489275

RESUMO

INTRODUCTION: The circadian rhythm of melatonin secretion is disturbed after general anaesthesia, leading to postoperative sleep disturbance. Small studies investigating the preventive effect of melatonin administration on postoperative sleep disturbance have not reached any conclusions. Therefore, we will conduct a systematic review and meta-analysis to obtain conclusive results. METHODS AND ANALYSIS: We prepared this protocol following the 2015 Preferred Reporting Items for Systematic Reviews and Meta-Analyses for Protocols guidelines. We will conduct a search for randomised controlled trials that evaluated the effect of melatonin and melatonin agonists on postoperative sleep quality in adult patients undergoing general anaesthesia or regional anaesthesia with sedation. We will exclude patients undergoing regional anaesthesia without sedation. Relevant studies will be searched in the following eight databases: MEDLINE, the Cochrane Central Register of Controlled Trials, Embase, Web of Science and four preregistration sites from inception to 1 January 2021. No language restrictions will be applied. Two authors will independently scan and select eligible studies and perform data extraction and assessment of the risk of bias. The Visual Analogue Scale scores for sleep quality will be combined as the mean difference with a 95% CI using a random-effect model; we will use I2 to assess heterogeneity. We will evaluate the quality of trials using the Cochrane methodology and assess the quality of evidence using the Grading of Recommendation Assessment, Development and Evaluation approach. If appropriate, trial sequential analysis will be performed. ETHICS AND DISSEMINATION: No ethical approval is required for this meta-analysis, as it does not include individual patient data. We will disseminate the results of this meta-analysis in a peer-reviewed journal. PROSPERO REGISTRATION NUMBER: CRD42020180167.


Assuntos
Melatonina , Transtornos do Sono-Vigília , Adulto , Humanos , Melatonina/uso terapêutico , Metanálise como Assunto , Sono , Transtornos do Sono-Vigília/prevenção & controle , Revisões Sistemáticas como Assunto
2.
BMC Psychol ; 9(1): 141, 2021 Sep 15.
Artigo em Inglês | MEDLINE | ID: mdl-34526155

RESUMO

BACKGROUND: Sleep is critical for maintaining homeostasis in bodily and neurobehavioral functions. This homeostasis can be disturbed by sleep interruption and restored to normal by subsequent recovery sleep. Most research regarding recovery sleep (RS) effects has been conducted in specialized sleep laboratories, whereas small, less-well equipped research units may lack the possibilities to run studies in this area. Hence, the aims of the present study were to develop and validate an experimental protocol, which allows a thorough assessment of at-home recovery sleep after sleep deprivation. METHODS: The experimental protocol, comprising one night of baseline sleep (BL) at home, one night of monitored total sleep deprivation and a subsequent recovery night at home, was tested in a sample of 30 healthy participants. Subjects' fatigue and alertness were assessed prior to and after each night. Sleep at home (BL, RS) was objectively assessed using portable polysomnography. To check whether our at-home sleep assessments yielded results that are comparable to those conducted in sleep laboratories, we compared the sleep data assessed in our study with sleep data assessed in laboratory studies. RESULTS: Sleep parameters assessed during RS exhibited changes as expected (prolonged total sleep time, better sleep efficiency, slow wave sleep rebound). Sleep parameters of BL and RS were in line with parameters assessed in previous studies examining sleep in a laboratory setting. Fatigue normalized after one night of RS; alertness partly recovered. CONCLUSIONS: Our results suggest a successful implementation of our new experimental protocol, emphasizing it as a useful tool for future studies on RS outside of well-equipped sleep laboratories.


Assuntos
Laboratórios , Privação do Sono , Humanos , Polissonografia , Sono , Vigília
3.
Rev Esc Enferm USP ; 55: e20200507, 2021.
Artigo em Inglês, Português | MEDLINE | ID: mdl-34479309

RESUMO

OBJECTIVE: To review the literature on sleep changes and brain function in children with microcephaly due to Zika virus. METHOD: Systematic review conducted in the databases MEDLINE (PubMed), Scopus, Web of Science, CINAHL, EMBASE, LILACS, and SciELO and the grey databases Google Scholar and OpenGrey. RESULTS: Ten Brazilian primary studies with observational research design were included. These were published between 2017 and 2020 with 516 children with microcephaly due to Zika virus infection aged 4 months to 4 years. Out of these, 4 investigated qualitative aspects of sleep using the questionnaires Brief Infant Sleep Questionnaire or Infant Sleep Questionnaire and 6 investigated changes in brain activities during sleep using the Electroencephalogram or Video-Electroencephalogram exams. The children's quality of sleep was not compromised in most studies. Changes in brain activity during sleep were frequent, with epileptogenic activity being a common finding among the studies. CONCLUSION: The quality of sleep of children with microcephaly due to Zika virus has shown to be similar to that of children with typical development and the presented behavioral changes may be related to changes in electric brain activity.


Assuntos
Microcefalia , Complicações Infecciosas na Gravidez , Infecção por Zika virus , Zika virus , Brasil , Criança , Feminino , Humanos , Lactente , Gravidez , Sono , Infecção por Zika virus/complicações
4.
Artigo em Russo | MEDLINE | ID: mdl-34481429

RESUMO

Circadian rhythm of pineal melatonin production is paced by the thalamus suprachiasmatic nucleus (SCN) depending on the lighting conditions via signal transduction to pinealocytes beta-receptors. Melatonin is a natural regulator of many physiological processes, and the decrease of its synthesis leads to various diseases, in particular, insomnia and metabolic disorders. It is known that administration of beta-blockers reduces melatonin production, but the data showing clinical significance of melatonin reduction associated with beta-blockers administration are still contradictory. OBJECTIVE: The influence of long-term administration of beta-blockers to melatonin synthesis, sleep quality and vascular brain damage. MATERIALS AND METHODS: The main study group included 114 patients, aged 47-83, with cardiovascular diseases, who were under a complex therapy with long-term administration of beta-blockers. The comparison group included 110 patients with cardiovascular diseases, similar in age and sex, who did not receive beta-blockers in their complex therapy. The circadian dynamics of melatonin synthesis was observed by excretion of 6-sulfatoxymelatonin (6-SM), the major metabolite of melatonin, in three urinary samples (day, evening, night). All the patients underwent night polysomnography to assess the severity of sleep disorders. The severity of vascular brain damage was assessed using magnetic resonance imaging. RESULTS: The analyses showed large variability in individual values of 6-SM circadian excretion of patients with cardiovascular diseases (from 0.9 to 133 µg/24h with a mid-point 16.8 µg/24h). A considerable decrease of 6-SM circadian excretion is detected in the group of patients taking beta-blockers comparing to those not Me [q 25; q 75]: 12.8 [6.2; 21.1] and 24.0 [12.5; 41.5] µg/24h, respectively (p<0.001), with no differences in sleep values and severity of vascular brain damage. Comparing subgroups of patients with 6-SM circadian excretion lower and higher than 16.8 µg/24h showed a significant increase of sleep latency, decrease of rapid eye movement sleep (REM sleep), increasing number of gliosis foci in white matter of the brain with higher values of leptin, leptin/adiponectin ratio and glycohemoglobin in the group of patients with 6-SM circadian excretion ≤16.8 µg/24h. CONCLUSION: A low level of endogenous melatonin is a risk factor for development of sleep structure and quality disorders, vascular white matter brain damages with a higher risk for metabolic disorders. Long-term beta-blockers administration decrease endogenous melatonin synthesis to 50% increasing the risk for insomnia and vascular brain damage, mostly in patients with lower initial level of 6-SM circadian excretion.: melatonin, 6-sulfatoxymelatonin, beta-blockers, insomnia, vascular white matter brain damage, leptin, adiponectin.


Assuntos
Melatonina , Transtornos do Sono-Vigília , Ritmo Circadiano , Humanos , Sono , Núcleo Supraquiasmático
5.
Nurs Open ; 8(3): 1030-1037, 2021 05.
Artigo em Inglês | MEDLINE | ID: mdl-34482659

RESUMO

AIM: This study aimed to examine the sleep pattern of breast cancer survivors and anxiety and depression associated with sleep quality to provide evidence-based information for the development of interventions to improve sleep disorders in these survivors. DESIGN: A cross-sectional study. METHODS: The subjects were 266 breast cancer survivors in South Korea. Structured questionnaires regarding sleep quality, anxiety and depression were used. The data were analysed using t test, ANOVA and multiple regression analysis. RESULTS: Sleep duration and sleep disturbance were found to affect anxiety, whereas sleep latency and subjective sleep quality were found to affect depression. These results suggest that various factors affecting sleep quality should be considered when providing care for anxiety and depression in breast cancer survivors.


Assuntos
Neoplasias da Mama , Sobreviventes de Câncer , Ansiedade/epidemiologia , Neoplasias da Mama/complicações , Estudos Transversais , Depressão/epidemiologia , Feminino , Humanos , República da Coreia/epidemiologia , Sono , Sobreviventes
6.
Rev Assoc Med Bras (1992) ; 67(3): 373-377, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-34468600

RESUMO

OBJECTIVE: To analyze the use of a mobile physical activity application and its influence on body composition and sleep quality in overweight children. METHODS: Prospective study with 37 patients from the Child and Adolescent Obesity Clinic at Unicamp Hospital das Clínicas, between 2018 and 2019. Anamnesis and anthropometry were performed. We oriented the use of the application for six weeks, five days/week for ten minutes. RESULTS: Among 37 patients, 28 (mean age 10.7±2.0 years, 50% boys) used the application. The average use of the application ranged from 1.93±2.18 to 3.25±1.84 times/week, with a peak in the second week and a progressive decrease during follow-up. The paired t-test showed, on average, lean mass (t (27)=-2.91), weight (t (27)=-3.11) and height (t (27)=-3.79). After using the application, these were higher than before (all p<0.05). There was a significant difference in the proportion of children who presented difficulty sleeping (χ2 (1)=5.143) and insomnia (χ2 (1)=4.167). CONCLUSIONS: There was an improvement in sleep quality and an increase in lean mass, but no significant changes in BMI z-score, waist circumference, and body fat percentage.


Assuntos
Aplicativos Móveis , Obesidade Pediátrica , Adolescente , Composição Corporal , Índice de Massa Corporal , Criança , Exercício Físico , Feminino , Humanos , Masculino , Sobrepeso , Obesidade Pediátrica/complicações , Estudos Prospectivos , Sono
7.
J Assoc Physicians India ; 69(4): 11-12, 2021 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34470185

RESUMO

BACKGROUND: Sleep quality is poorly understood in the Indian population. Lack of a suitable tool to assess sleep quality in Hindi language is the main reason behind this. Pittsburg sleep quality index (PSQI) is widely used in different population groups to assess subjective sleep quality over last one month. OBJECTIVES: To assess the reliability and validity of the Hindi translated version of Pittsburgh Sleep Quality Index (PSQI-H). gt;Methods: The PSQI-H was developed from PSQI according to following steps: (a) translation, (b) back-translation, (c) comparison between translation and back-translation performed by a group of experts, and (d) pre-pilot test in intended population. The PSQI-H was applied to 105 bilingual individuals knowing Hindi and English. The internal consistency of PSQI-H was assessed by Cronbach's alpha. For test-retest reliability assessment intraclass correlation coefficient (ICC) was measured between PSQI-H at baseline and PSQI after 4 weeks. The Pearson's coefficient was used to assess the correlation between the score of the questions and the PSQI-H scores. RESULTS: The seven components of PSQI-H shows acceptable level of internal consistency with Cronbach's alpha of 0.776. There is good test-retest reliability between PSQI-H and PSQI as measured by ICC of 0.979. The score of individual items and global scores of PSQI-H were highly correlated with each other (p< 0.001). The mean of the seven individual components score and global scores of PSQI-H at baseline and original PSQI after 4 weeks did not differ significantly. CONCLUSION: This study results demonstrate that the PSQI-H is a valid and reliable instrument for the assessment of sleep quality. PSQI-H can be used for the assessment of sleep quality in the predominantly Hindi speaking population.


Assuntos
Idioma , Sono , Humanos , Psicometria , Reprodutibilidade dos Testes , Inquéritos e Questionários
8.
Croat Med J ; 62(4): 376-386, 2021 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-34472741

RESUMO

Malignant brain tumors are among the most aggressive human neoplasms. One of the most common and severe symptoms that patients with these malignancies experience is sleep disruption. Disrupted sleep is known to have significant systemic pro-tumor effects, both in patients with other types of cancer and those with malignant brain lesions. We therefore provide a review of the current knowledge on disrupted sleep in malignant diseases, with an emphasis on malignant brain tumors. More specifically, we review the known ways in which disrupted sleep enables further malignant progression. In the second part of the article, we also provide a theoretical framework of the reverse process. Namely, we argue that due to the several possible pathophysiological mechanisms, patients with malignant brain tumors are especially susceptible to their sleep being disrupted and compromised. Thus, we further argue that addressing the issue of disrupted sleep in patients with malignant brain tumors can, not just improve their quality of life, but also have at least some potential of actively suppressing the devastating disease, especially when other treatment modalities have been exhausted. Future research is therefore desperately needed.


Assuntos
Neoplasias Encefálicas , Qualidade de Vida , Neoplasias Encefálicas/complicações , Humanos , Sono
9.
BMC Public Health ; 21(1): 1617, 2021 09 05.
Artigo em Inglês | MEDLINE | ID: mdl-34482826

RESUMO

BACKGROUND: Although pain has been identified as an important public health problem among adolescents, few studies have investigated possible protective and risk factors for pain. The main aim of the present study was to investigate associations between prevalence of daily pain, self-efficacy, sleep duration, and symptoms of depression in a representative sample of Norwegian adolescents. METHODS: A comprehensive cross-sectional survey was completed by 12,867 junior high school students and high school students (response rate: 90%) aged 14-19 years. Logistic regression models were adjusted for age, gender, and parental educational level. RESULTS: We found a high prevalence of daily pain among adolescents, especially among girls (19%) compared with boys (7%). Short sleep duration was associated with increased odds ratios (ORs) of pain in the shoulders/neck (OR 1.3; 95% CI 1.3-2.0) and stomach (1.7; 1.2-2.4). Symptoms of depression were associated with increased ORs for all measured types of daily pain, including head (3.7; 3.0-4.6), shoulders/neck (3.9; 3.1-4.8), joints/muscles (4.3; 3.3-5.6), and stomach (5.5; 4.1-7.4). By contrast, self-efficacy was not associated with any form of daily pain. CONCLUSION: Given the burden of pain, high incidence of pain problems, and strong association between pain and depression and, to some degree, short sleep duration, co-occurring symptoms may be an important area for research in the public health field. The results highlight the importance of early identification and prevention. Longitudinal studies are needed to understand better pain problems and their underlying mechanisms with the aim of developing targeted interventions.


Assuntos
Depressão , Autoeficácia , Adolescente , Estudos Transversais , Depressão/epidemiologia , Feminino , Humanos , Masculino , Dor , Sono , Inquéritos e Questionários
10.
Artigo em Inglês | MEDLINE | ID: mdl-34501845

RESUMO

This study aimed to examine the impact of the COVID-19 pandemic on the 24 h movement behaviors of adolescents. This was conducted to capture their evolution from February to December 2020, as well as to explore the use of technology for physical activity purposes by adolescents as a strategy to increase their physical activity during the pandemic. Physical activity, recreational screen time, sleep duration, and sleep quality were self-reported by 2661 adolescents using an online questionnaire. Participants also indicated, in comparison with the previous winter (regular in-class learning), how their different movement behaviors changed during the following 2020 periods: (1) spring (school closures), (2) summer (school break), and (3) autumn (hybrid learning). Finally, information about the use of technology during physical activity was collected. Results show that the 24 h movement behaviors of the participants varied across the different periods, and these variations were consistent with the restrictive measures imposed by the government. It was also observed that the negative effects of the COVID-19 pandemic on sleep duration and quality peaked in autumn. Finally, participants' physical activity levels were associated with the use of physical activity-related tools and applications. In conclusion, the restrictive measures due to the COVID-19 pandemic worsened the situation of the 24 h movement behaviors in adolescents, which has become critical.


Assuntos
COVID-19 , Adolescente , Humanos , Pandemias , SARS-CoV-2 , Tempo de Tela , Comportamento Sedentário , Sono
11.
Artigo em Inglês | MEDLINE | ID: mdl-34501935

RESUMO

BACKGROUND: Mental health problems are prevalent among university students in Saudi Arabia. This study aimed to investigate the impact of the COVID-19 pandemic on university students' mental health and sleep in Saudi Arabia. METHOD: A total of 582 undergraduate students from Saudi Arabia aged between 18 and 45 years old (M = 20.91, SD = 3.17) completed a cross-sectional online questionnaire measuring depression, anxiety, stress, resilience, and insomnia during the COVID-19 pandemic (2020). Analysis included an independent samples t-test, one-way ANOVA, and Hierarchical regression analysis. RESULTS: Undergraduate students reported high levels of depression, anxiety, and perceived stress and low levels of resilience (p < 0.001) during the pandemic. In addition, students reported experiencing insomnia. A hierarchical regression analysis indicated that lower resilience, high levels of insomnia, having a pre-existing mental health condition, and learning difficulties (such as dyslexia, dyspraxia, or dyscalculia) were significantly associated with high levels of depression and stress. In addition, lower resilience, a high level of insomnia, and pre-existing mental health conditions were significantly associated with high levels of anxiety. Finally, a lower level of psychological resilience and a high level of insomnia were significantly associated with increased levels of depression, anxiety and stress within university students. CONCLUSION: This study has provided evidence that a lower level of psychological resilience and insomnia were associated with mental health problems among undergraduate students in Saudi Arabia, thus enhancing psychological resilience and interventions to support sleep and mental health are vital to support student well-being outcomes throughout the pandemic.


Assuntos
COVID-19 , Pandemias , Adolescente , Adulto , Ansiedade/epidemiologia , Estudos Transversais , Depressão/epidemiologia , Humanos , Saúde Mental , Pessoa de Meia-Idade , SARS-CoV-2 , Arábia Saudita/epidemiologia , Sono , Estudantes , Adulto Jovem
12.
BMC Pediatr ; 21(1): 374, 2021 08 31.
Artigo em Inglês | MEDLINE | ID: mdl-34465311

RESUMO

BACKGROUND: Overweight, obesity, and associated comorbidities are a pressing global issue among children of all ages, particularly among low-income populations. Rapid weight gain (RWG) in the first 6 months of infancy contributes to childhood obesity. Suboptimal sleep-wake patterns and gut microbiota (GM) have also been associated with childhood obesity, but little is known about their influences on early infant RWG. Sleep may alter the GM and infant metabolism, and ultimately impact obesity; however, data on the interaction between sleep-wake patterns and GM development on infant growth are scarce. In this study, we aim to investigate associations of infant sleep-wake patterns and GM development with RWG at 6 months and weight gain at 12 months. We also aim to evaluate whether temporal interactions exist between infant sleep-wake patterns and GM, and if these relations influence RWG. METHODS: The Snuggle Bug/ Acurrucadito study is an observational, longitudinal study investigating whether 24-h, actigraphy-assessed, sleep-wake patterns and GM development are associated with RWG among infants in their first year. Based on the Ecological Model of Growth, we propose a novel conceptual framework to incorporate sleep-wake patterns and the GM as metabolic contributors for RWG in the context of maternal-infant interactions, and familial and socio-physical environments. In total, 192 mother-infant pairs will be recruited, and sleep-wake patterns and GM development assessed at 3 and 8 weeks, and 3, 6, 9, and 12 months postpartum. Covariates including maternal and child characteristics, family and environmental factors, feeding practices and dietary intake of infants and mothers, and stool-derived metabolome and exfoliome data will be assessed. The study will apply machine learning techniques combined with logistic time-varying effect models to capture infant growth and aid in elucidating the dynamic associations between study variables and RWG. DISCUSSION: Repeated, valid, and objective assessment at clinically and developmentally meaningful intervals will provide robust measures of longitudinal sleep, GM, and growth. Project findings will provide evidence for future interventions to prevent RWG in infancy and subsequent obesity. The work also may spur the development of evidence-based guidelines to address modifiable factors that influence sleep-wake and GM development and prevent childhood obesity.


Assuntos
Microbioma Gastrointestinal , Obesidade Pediátrica , Criança , Feminino , Humanos , Lactente , Estudos Longitudinais , Obesidade Pediátrica/etiologia , Fatores de Risco , Sono , Ganho de Peso
13.
BMJ ; 374: n1034, 2021 09 08.
Artigo em Inglês | MEDLINE | ID: mdl-34497047

RESUMO

OBJECTIVE: To determine the benefits and harms of medical cannabis and cannabinoids for chronic pain. DESIGN: Systematic review and meta-analysis. DATA SOURCES: MEDLINE, EMBASE, AMED, PsycInfo, CENTRAL, CINAHL, PubMed, Web of Science, Cannabis-Med, Epistemonikos, and trial registries up to January 2021. STUDY SELECTION: Randomised clinical trials of medical cannabis or cannabinoids versus any non-cannabis control for chronic pain at ≥1 month follow-up. DATA EXTRACTION AND SYNTHESIS: Paired reviewers independently assessed risk of bias and extracted data. We performed random-effects models meta-analyses and used GRADE to assess the certainty of evidence. RESULTS: A total of 32 trials with 5174 adult patients were included, 29 of which compared medical cannabis or cannabinoids with placebo. Medical cannabis was administered orally (n=30) or topically (n=2). Clinical populations included chronic non-cancer pain (n=28) and cancer related pain (n=4). Length of follow-up ranged from 1 to 5.5 months. Compared with placebo, non-inhaled medical cannabis probably results in a small increase in the proportion of patients experiencing at least the minimally important difference (MID) of 1 cm (on a 10 cm visual analogue scale (VAS)) in pain relief (modelled risk difference (RD) of 10% (95% confidence interval 5% to 15%), based on a weighted mean difference (WMD) of -0.50 cm (95% CI -0.75 to -0.25 cm, moderate certainty)). Medical cannabis taken orally results in a very small improvement in physical functioning (4% modelled RD (0.1% to 8%) for achieving at least the MID of 10 points on the 100-point SF-36 physical functioning scale, WMD of 1.67 points (0.03 to 3.31, high certainty)), and a small improvement in sleep quality (6% modelled RD (2% to 9%) for achieving at least the MID of 1 cm on a 10 cm VAS, WMD of -0.35 cm (-0.55 to -0.14 cm, high certainty)). Medical cannabis taken orally does not improve emotional, role, or social functioning (high certainty). Moderate certainty evidence shows that medical cannabis taken orally probably results in a small increased risk of transient cognitive impairment (RD 2% (0.1% to 6%)), vomiting (RD 3% (0.4% to 6%)), drowsiness (RD 5% (2% to 8%)), impaired attention (RD 3% (1% to 8%)), and nausea (RD 5% (2% to 8%)), but not diarrhoea; while high certainty evidence shows greater increased risk of dizziness (RD 9% (5% to 14%)) for trials with <3 months follow-up versus RD 28% (18% to 43%) for trials with ≥3 months follow-up; interaction test P=0.003; moderate credibility of subgroup effect). CONCLUSIONS: Moderate to high certainty evidence shows that non-inhaled medical cannabis or cannabinoids results in a small to very small improvement in pain relief, physical functioning, and sleep quality among patients with chronic pain, along with several transient adverse side effects, compared with placebo. The accompanying BMJ Rapid Recommendation provides contextualised guidance based on this body of evidence. SYSTEMATIC REVIEW REGISTRATION: https://osf.io/3pwn2.


Assuntos
Dor do Câncer/tratamento farmacológico , Canabinoides/efeitos adversos , Dor Crônica/tratamento farmacológico , Maconha Medicinal/administração & dosagem , Adulto , Canabinoides/administração & dosagem , Feminino , Humanos , Masculino , Maconha Medicinal/efeitos adversos , Diferença Mínima Clinicamente Importante , Medição da Dor , Ensaios Clínicos Controlados Aleatórios como Assunto , Sono/efeitos dos fármacos
14.
Sultan Qaboos Univ Med J ; 21(3): 394-402, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34522404

RESUMO

Objectives: Disturbed sleep patterns might alter the autonomic tone and lead to various cardiovascular morbidities. This study aimed to determine sleep patterns (quality, duration, efficiency and daytime sleepiness) and explore their association with blood pressure (BP) and heart rate variability (HRV) in apparently healthy, young Saudi females. Methods: This cross-sectional study was conducted in the Department of Physiology, Imam Abdulrahman Bin Faisal University, Saudi Arabia between March 2019 and December 2019. Self-reported Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale questionnaires were used to collect data. In addition, the participants' BP and HRV was measured. Based on the cut-off values of sleep quality, duration, efficiency and daytime sleepiness scores, participants were categorised into groups. HRV and BP were compared between the groups by a t-test/one-way ANOVA. Results: A total of 98 participants were included in this study (response rate: 72.6%). Poor sleep patterns (quality, duration and efficiency) were observed, but no association was found with BP and HRV parameters among groups with different sleep quality, duration and efficiency. Systolic BP was significantly increased in the moderate to severe daytime sleepiness group (P = 0.039). Dozing off as a passenger in a car, in the afternoon and after lunch were negatively correlated with HRV parameters (P <0.05). Conclusion: Sleep quality, duration and efficiency were not found to be statistically significant, but various dozing-off situations were associated with fluctuations in HRV parameters. Daytime sleepiness may augment sympathetic responses in apparently healthy female participants.


Assuntos
Sono , Pressão Sanguínea , Estudos Transversais , Feminino , Frequência Cardíaca , Humanos , Arábia Saudita/epidemiologia
15.
BMC Pediatr ; 21(Suppl 1): 320, 2021 09 08.
Artigo em Inglês | MEDLINE | ID: mdl-34496779

RESUMO

We looked at existing recommendations and supporting evidence for successful strategies to prevent the sudden infant death syndrome (SIDS).We conducted a literature search up to the 14th of December 2020 by using key terms and manual search in selected sources. We summarized the recommendations and the strength of the recommendation when and as reported by the authors. We summarized the main findings of systematic reviews with the certainty of the evidence as reported.Current evidence supports statistical associations between risk factors and SIDS, but there is globally limited evidence by controlled studies assessing the effect of the social promotion strategies to prevent SIDS through knowledge, attitude and practices, due to obvious ethical reasons. A dramatic decline in SIDS incidence has been observed in many countries after the introduction of "Back to Sleep" campaigns for prevention of SIDS. All infants should be placed to sleep in a safe environment including supine position, a firm surface, no soft objects and loose bedding, no head covering, no overheating, and room-sharing without bed-sharing. Breastfeeding on demand and the use of pacifier during sleep time protect against SIDS and should be recommended. Parents should be advised against the use of tobacco, alcohol and illicit drugs during gestation and after birth.


Assuntos
Morte Súbita do Lactente , Leitos , Humanos , Lactente , Chupetas , Decúbito Ventral , Fatores de Risco , Sono , Morte Súbita do Lactente/epidemiologia , Morte Súbita do Lactente/etiologia , Morte Súbita do Lactente/prevenção & controle , Decúbito Dorsal , Revisões Sistemáticas como Assunto
16.
Sensors (Basel) ; 21(17)2021 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-34502748

RESUMO

One of the most common sleep disorders is sleep apnea. It manifests itself by episodes of shallow breathing or pauses in breathing during the night. Diagnosis of this disease involves polysomnography examination, which is expensive. Alternatively, diagnostic doctors can be supported with recordings from the in-home polygraphy sensors. Furthermore, numerous attempts for providing an automated apnea episodes annotation algorithm have been made. Most of them, however, do not distinguish between apnea and hypopnea episodes. In this work, a novel solution for epoch-based annotation problem is presented. Utilizing an architecture based on the long short-term memory (LSTM) networks, the proposed model provides locations of sleep disordered breathing episodes and identifies them as either apnea or hypopnea. To achieve this, special pre- and postprocessing steps have been designed. The obtained labels can be then used for calculation of the respiratory event index (REI), which serves as a disease severity indicator. The input for the model consists of the oronasal airflow along with the thoracic and abdominal respiratory effort signals. Performance of the proposed architecture was verified on the SHHS-1 and PhysioNet Sleep databases, obtaining mean REI classification error of 9.24/10.52 with standard deviation of 11.61/7.92 (SHHS-1/PhysioNet). Normal breathing, hypopnea and apnea differentiation accuracy is assessed on both databases, resulting in the correctly classified samples percentage of 86.42%/84.35%, 49.30%/58.28% and 68.20%/69.50% for normal breathing, hypopnea and apnea classes, respectively. Overall accuracies are 80.66%/82.04%. Additionally, the effect of wake periods is investigated. The results show that the proposed model can be successfully used for both episode classification and REI estimation tasks.


Assuntos
Síndromes da Apneia do Sono , Humanos , Polissonografia , Respiração , Taxa Respiratória , Sono , Síndromes da Apneia do Sono/diagnóstico
17.
Rev Lat Am Enfermagem ; 29: e3444, 2021.
Artigo em Inglês, Português, Espanhol | MEDLINE | ID: mdl-34468620

RESUMO

OBJECTIVE: to determine the prevalence of sleep quality and common mental disorder in Nursing professionals and factors associated with sleep change. METHOD: a cross-sectional, analytical and quantitative study developed with 196 Nursing professionals of a public hospital and a mixed one. Data was collected by means of an instrument of sociodemographic characterization, by the Self-Report Questionnaire 20 and Pittsburgh Sleep Quality Index and were analyzed by descriptive and inferential statistics to identify possible factors associated with sleep changes. RESULTS: sleep changes were identified among the Nursing professionals with a frequency of 76.5% (70.4-82.1). Sleep quality was classified as poor in 41.8% (41.8-55.6) and sleep disorder in 27.6%. (21.4-34.2). The prevalence of common mental disorder was identified in 36.7% (30.1-43.9). The main factor for poor sleep quality was the presence of common mental disorder (Odds Ratio: 5.15; p<0.001). CONCLUSION: sleep changes were prevalent and the characteristics of the work environment and the presence of mental disorder showed relevance in the changes.


Assuntos
Transtornos Mentais , Transtornos do Sono-Vigília , Estudos Transversais , Hospitais , Humanos , Transtornos Mentais/epidemiologia , Prevalência , Sono , Transtornos do Sono-Vigília/epidemiologia , Inquéritos e Questionários
18.
BMJ Open ; 11(9): e047834, 2021 09 02.
Artigo em Inglês | MEDLINE | ID: mdl-34475161

RESUMO

OBJECTIVE: To investigate whether sleep disparities vary by birthplace among non-Hispanic White (NHW) and Hispanic/Latino adults in the USA and to investigate language preference as an effect modifier. DESIGN: Cross-sectional. SETTING: USA. PARTICIPANTS: 254 699 men and women. METHODS: We used pooled 2004-2017 National Health Interview Survey data. Adjusting for sociodemographic and behavioural/clinical characteristics, survey-weighted Poisson regressions with robust variance estimated prevalence ratios (PRs) and 95% CIs of self-reported sleep characteristics (eg, sleep duration, trouble staying asleep) among (1) foreign-born NHW adults and Hispanic/Latino heritage groups versus US-born NHW adults and (2) Hispanic/Latino heritage groups versus foreign-born NHW adults. We further stratified by language preference in comparisons of Hispanic/Latino heritage groups with the US-born NHW group. RESULTS: Among 254 699 participants with a mean age±SE 47±0.9 years, 81% self-identified their race/ethnicity as NHW, 12% Mexican, 2% Puerto Rican, 1% Cuban, 1% Dominican and 3% Central/South American. Compared with US-born NHW adults, foreign-born NHW adults were more likely to report poor sleep quality (eg, PRtrouble staying asleep=1.27 (95% CI: 1.17 to 1.37)), and US-born Mexican adults were no more likely to report non-recommended sleep duration while foreign-born Mexican adults were less likely (eg, PR≤5-hours=0.52 (0.47 to 0.57)). Overall, Mexican adults had lower prevalence of poor sleep quality versus US-born NHW adults, and PRs were lowest for foreign-born Mexican adults. US-born Mexican adults were more likely than foreign-born NHW adults to report shorter sleep duration. Regardless of birthplace, Puerto Rican adults were more likely to report shorter sleep duration versus NHW adults. Generally, sleep duration and quality were better among Cuban and Dominican adults versus US-born NHW adults but were similar versus foreign-born NHW adults. Despite imprecision in certain estimates, Spanish language preference was generally associated with increasingly better sleep among Hispanic/Latino heritage groups compared with US-born NHW adults. CONCLUSION: Sleep disparities varied by birthplace, Hispanic/Latino heritage and language preference, and each characteristic should be considered in sleep disparities research.


Assuntos
Grupos Étnicos , Idioma , Adulto , Estudos Transversais , Feminino , Hispano-Americanos , Humanos , Masculino , Pessoa de Meia-Idade , Sono , Estados Unidos/epidemiologia
19.
Acta Otorhinolaryngol Ital ; 41(4): 348-355, 2021 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-34533538

RESUMO

Objective: This study aimed to describe the sound frequency of snoring in relation to the site of upper airway vibration among snorers. Methods: 383 snores from 40 participants who complained of snoring were digitally recorded during natural and induced sleep using a level III polysomnography monitor with a built-in microphone. During drug-induced sleep endoscopy (DISE), the real-time site of upper airway obstruction was assessed, and the sound frequency of snoring was recorded synchronously. Results: The mean peak of snoring frequency for unilevel palatal, oropharynx and epiglottis obstruction were 522.5, 482.4 and 300.0 Hz, respectively. Most participants showed multilevel obstruction at the palate and oropharynx, in which the mean for bi-peak snoring frequency were 402.90 Hz and 1086.96 Hz, respectively. Severity of OSA was significantly associated with multilevel obstruction. Conclusions: There was a significant association between the snoring sound frequency and site of unilevel obstruction. Palatal or oropharyngeal obstruction produced sound at mid-frequency range, while the epiglottis produced a low frequency range. Multilevel obstruction documented a bi-peak snoring frequency.


Assuntos
Obstrução das Vias Respiratórias , Apneia Obstrutiva do Sono , Obstrução das Vias Respiratórias/etiologia , Epiglote , Humanos , Polissonografia , Sono , Ronco/epidemiologia
20.
An. psicol ; 37(2): 393-402, mayo-sept. 2021. tab, graf
Artigo em Espanhol | IBECS | ID: ibc-202562

RESUMO

Professional drivers often have problems sleeping or resting properly. This may be due to various factors, both personal and specific to their working conditions. In this study, we set out to develop a predictive model for the quality of sleep in professional drivers using the following indicators: Age, Gender, Seat Comfort, Seat Suspension, Adjustable Lum-bar Support of the Driver's Seat, Driving Hours, Musculoskeletal Problems, Driver Stress, Irritation, Resistant Personality, Burnout, Safety Behaviors and Impulsivity. METHOD: The participants were 369 professional drivers from different transport sectors, obtained through non-probabilistic sampling. The SPSS 25.0 program was used for statistical analysis. RESULTS: The predictive capacity of certain variables that affect drivers' sleep quality is determined. CONCLUSIONS: Sleep quality can be predicted by means of certain variables, the best predictor of which is Exhaustion (Burnout). This research contributes to the body of knowledge on sleep quality and on improving the health of professional drivers


Los conductores profesionales suelen padecer problemas para dormir o descansar correctamente. Esto puede deberse a diversos factores tanto personales como específicos de las condiciones laborales. En el presente trabajo nos hemos planteado desarrollar un modelo predictivo sobre la calidad del sueño en conductores profesionales utilizando los indicadores siguientes: Edad, Género, Confort del asiento, suspensión del asiento, Soporte lumbar ajustable del asiento del conductor, Horas de conducción, Problemas musculoesqueléticos, Drivers Stress, Irritación, Personalidad resistente, Burnout, conductas de seguridad e Impulsividad. MÉTODO: Los participantes han sido 369 conductores profesionales, de distintos sectores del transporte, obtenidos mediante un muestreo no probabilístico. Se han utilizado el programa SPSS 25.0. RESULTADOS: Se determina la capacidad predictiva de algunas variables que afectan a los conductores sobre la calidad del sueño. CONCLUSIONES: La calidad del sueño se puede predecir a través de determinadas variables, siendo la mejor predictora Exhaustion (Burnout). Esta investigación contribuye a un mayor conocimiento de la calidad del sueño y a la mejora de la salud de los conductores profesionales


Assuntos
Humanos , Masculino , Feminino , Adulto , Pessoa de Meia-Idade , Condução de Veículo/psicologia , Sono/fisiologia , Saúde do Trabalhador , Esgotamento Profissional/psicologia , Comportamento Impulsivo , Inquéritos e Questionários , Valores de Referência , Análise de Regressão , Fatores Sexuais , Fatores Etários , Condições de Trabalho , Fatores de Tempo
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