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1.
Texto & contexto enferm ; 29: e20180407, Jan.-Dec. 2020.
Artigo em Inglês | LILACS, BDENF - Enfermagem | ID: biblio-1059137

RESUMO

ABSTRACT Objective: to analyze university teaching in nursing from an institutional dialectic approach. Method: a qualitative research based on Institutional Socioclinics. Eighteen nursing professors from four regions of Brazil and from six public institutions of higher education participated. For data production, interviews, observations, documentary analyses, individual and collective restitution and use of the research diary were performed. Data was organized for analysis by transcription/translation, recomposition/rearrangement, and final reconstruction/narration. Data analysis was produced from analyzers, based on Socioclinics, Institutional Analysis current of thought, and on the qualitative mode of analysis by questioning and writing. Results: two main analyzers made the institution 'teaching in higher education and the nursing professor' emerge: time-money relation and resistance. Teaching time, increasingly associated with money, in managerialist logic, has formatted the nursing professors as passive subjects in the production of knowledge, induced by the evaluation model of the Coordination for the Improvement of Higher Level Personnel and its link to the progression in the university career. In this model, the nursing professor is driven to devote more to research than to teaching. This interferes with teaching conceptions and practices, which are more influenced by managerialism and less grounded in pedagogical theories. Resistance against this model has not yet encountered coping mechanisms. Conclusion: from the analysis produced with the participants, the choices of the nursing professor are so much more grounded in managerialism and so much less based on pedagogical references, especially those arising from dialectical theories. In this sense, resistance is transformed into a movement of adaptation.


RESUMEN Objetivo: analizar la docencia universitaria en enfermería a partir de la dialéctica institucional. Método: investigación cualitativa fundamentada en la Socioclínica Institucional. Participaron 18 profesores-enfermeros de cuatro regiones de Brasil y seis establecimientos públicos de educación superior. Para producir los datos se realizaron entrevistas, observaciones, análisis documentales, restituciones individuales y colectivas, además de utilizarse un diario de investigación. La organización de los datos para su análisis se dio mediante la transcripción/traducción de los mismos, su recomposición/reordenamiento, y por su reconstitución/narración final. El análisis de los datos se produjo a partir de analizadores, y se fundamentó en la Socioclínica, una vertiente del Análisis Institucional, y en la modalidad cualitativa de análisis por cuestionamiento y en forma escrita. Resultados: dos analizadores principales hicieron surgir la institución de 'docencia en la educación superior y el profesor-enfermero', a saber: relación tiempo/dinero y resistencia. El tiempo docente, cada vez más asociado al dinero en la lógica gerencialista, ha conformado al profesor-enfermero como un sujeto pasivo en la producción de conocimientos, inducido por el modelo evaluativo de la Coordinación de Perfeccionamiento para Personal de Nivel Superior y su vínculo con el avance en la carrera universitaria. En ese modelo, el profesor-enfermero está motivado a dedicarse más a la investigación que a la enseñanza. Eso interfiere con las concepciones y prácticas docentes, que quedan más influenciadas por el gerencialismo y menos fundamentadas en teorías pedagógicas. La resistencia contra ese modelo todavía no encontró mecanismos de confrontación. Conclusión: de acuerdo con el análisis elaborado con los participantes, las elecciones de los profesores-enfermeros están tanto más fundamentadas en el gerencialismo como menos basadas en referenciales pedagógicos, especialmente en aquellos devenidos de teorías dialécticas. En este sentido, la resistencia se transforma en un movimiento de adaptación.


RESUMO Objetivo: analisar a docência universitária em enfermagem a partir da dialética institucional. Método: pesquisa qualitativa fundamentada na Socioclínica Institucional. Participaram 18 professores-enfermeiros de quatro Regiões do Brasil e seis estabelecimentos públicos de educação superior. Para a produção de dados, foram realizadas entrevistas, observações, análises documentais, restituições individuais e coletivas e uso do diário de pesquisa. A organização dos dados para análise se deu pela transcrição/tradução dos mesmos, pela recomposição/rearranjo, e pela reconstituição/narração final. A análise dos dados foi produzida a partir de analisadores, fundamentada na Socioclínica, vertente da Análise Institucional e na modalidade qualitativa de análise por questionamento e pela escrita. Resultados: dois principais analisadores fizeram a instituição 'docência no ensino superior e o professor-enfermeiro' emergir: relação tempo-dinheiro e resistência. O tempo docente, cada vez mais associado ao dinheiro, na lógica gerencialista, tem formatado o professor-enfermeiro como sujeito passivo na produção de conhecimentos, induzido pelo modelo avaliativo da Coordenação de Aperfeiçoamento de Pessoal de Nível Superior e seu atrelamento à progressão na carreira universitária. Nesse modelo, o professor-enfermeiro é impulsionado a se dedicar mais à pesquisa do que ao ensino. Isso interfere nas concepções e práticas docentes, que ficam mais influenciadas pelo gerencialismo e menos fundamentadas em teorias pedagógicas. A resistência contra esse modelo não encontrou ainda mecanismos de enfrentamento. Conclusão: pela análise produzida com os participantes, as escolhas dos professores-enfermeiros estão tão mais fundamentadas no gerencialismo e tão menos baseadas em referenciais pedagógicos, notadamente naqueles advindos de teorias dialéticas. Nesse sentido, resistir se transfigura em movimento de adaptar-se.


Assuntos
Humanos , Adulto , Ensino , Universidades , Indicadores de Produção Científica , Docentes de Enfermagem , Tempo , Conhecimento , Educação Superior , Docentes
3.
Best Pract Res Clin Anaesthesiol ; 34(3): 643-650, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33004173

RESUMO

During this coronavirus disease 2019 (COVID-19) pandemic, there is an international call to postpone all elective surgeries. Cardiac surgery carries a combined risk for cardiac patients, who are at risk for higher complications of COVID-19, and healthcare workers. In response to the COVID-19 pandemic, the American College of Surgeons and the American Society of Anesthesiologists recommended a sustained reduction in the rate of new COVID-19 cases for 14 days before the resumption of the elective surgery, but postponing surgery may impact patients' daily activities and increase the risk the of deterioration of their cardiac condition. We will discuss the risks and benefits of the decision whether to postpone or proceed with elective cardiac surgical procedures during the escalating COVID-19 pandemic considering the specific risk of the cardiac patients, the unique characteristics of the surgery, and the international health system capacity.


Assuntos
Betacoronavirus , Procedimentos Cirúrgicos Cardíacos , Infecções por Coronavirus/prevenção & controle , Procedimentos Cirúrgicos Eletivos , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Humanos , Tempo
4.
BMJ Case Rep ; 13(10)2020 Oct 04.
Artigo em Inglês | MEDLINE | ID: mdl-33012717

RESUMO

We present a case of COVID-19 in an immunocompetent patient with risk factors for severe disease who recovered after prolonged swab positivity of 61 days postsymptom onset without significant respiratory and organ dysfunction. We discuss the reasons behind her prolonged swab positivity in the context of current SARS-CoV-2 knowledge, document the trend in her inflammatory response and swab results, and discuss the implications swab positivity had on her isolation and recovery.


Assuntos
Betacoronavirus/imunologia , Infecções por Coronavirus/imunologia , Hospedeiro Imunocomprometido/imunologia , Pneumonia Viral/imunologia , Eliminação de Partículas Virais/imunologia , Idoso , Infecções por Coronavirus/terapia , Feminino , Humanos , Pandemias , Pneumonia Viral/terapia , Tempo , Carga Viral/imunologia
6.
Sci Rep ; 10(1): 16487, 2020 10 05.
Artigo em Inglês | MEDLINE | ID: mdl-33020508

RESUMO

The Italian Government has decreed a series of progressive restrictions to delay the COVID-19 pandemic diffusion in Italy since March 10, 2020, including limitation in individual mobility and the closure of social, cultural, economic and industrial activities. Here we show the lockdown effect in Northern Italy, the COVID-19 most affected area, as revealed by noise variation at seismic stations. The reaction to lockdown was slow and not homogeneous with spots of negligible noise reduction, especially in the first week. A fresh interpretation of seismic noise variations in terms of socio-economic indicators sheds new light on the lockdown efficacy pointing to the causes of such delay: the noise reduction is significant where non strategic activities prevails, while it is small or negligible where dense population and strategic activities are present. These results are crucial for the a posteriori interpretation of the pandemic diffusion and the efficacy of differently targeted political actions.


Assuntos
Infecções por Coronavirus/epidemiologia , Terremotos/estatística & dados numéricos , Pneumonia Viral/epidemiologia , Quarentena/estatística & dados numéricos , Infecções por Coronavirus/prevenção & controle , Humanos , Itália , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Razão Sinal-Ruído , Tempo
7.
BMJ Open Respir Res ; 7(1)2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32895247

RESUMO

The global pandemic of COVID-19 has challenged the management of hypoxaemic respiratory failure and strained intensive care unit resources. While prone positioning (PP) is an established therapy in mechanically ventilated patients with acute respiratory distress syndrome (ARDS), its role in conscious patients is less well defined. We retrospectively reviewed our experience of implementing early PP in a cohort of 24 patients with acute hypoxaemic respiratory failure due to COVID-19 who required support with continuous positive airway pressure (CPAP). The use of PP alongside CPAP significantly increased both the ROX index and arterial oxygen pressure:fractional inspired oxygen (PaO2:FiO2) ratio from baseline values (ROX index: 7.0±2.5 baseline vs 11.4±3.7 CPAP+PP, p<0.0001; PaO2:FiO2 ratio: 143±73 mm Hg baseline vs 252±87 mm Hg CPAP+PP, p<0.01), and the changes to both the ROX index and PaO2:FiO2 ratio remained significant 1 hour after cessation of proning. The mean duration of PP in the first 24 hours was 8±5 hours. Few complications were observed and PP was continued for a mean of 10±5 days. From our experience in a dedicated COVID-19 respiratory high care unit, PP alongside CPAP therapy was feasible, tolerated, safe and improved oxygenation. The use of conscious PP in ARDS warrants further investigation in randomised controlled trials.


Assuntos
Betacoronavirus , Pressão Positiva Contínua nas Vias Aéreas/métodos , Infecções por Coronavirus/terapia , Posicionamento do Paciente/métodos , Pneumonia Viral/terapia , Estudos de Coortes , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pandemias , Decúbito Ventral , Estudos Retrospectivos , Tempo , Resultado do Tratamento , Vigília
8.
Science ; 369(6510): 1431-1432, 2020 09 18.
Artigo em Inglês | MEDLINE | ID: mdl-32943512
9.
Proc Natl Acad Sci U S A ; 117(38): 23235-23241, 2020 09 22.
Artigo em Inglês | MEDLINE | ID: mdl-32967067

RESUMO

A now substantial body of science implicates a dynamic interplay between genetic and environmental variation in the development of individual differences in behavior and health. Such outcomes are affected by molecular, often epigenetic, processes involving gene-environment (G-E) interplay that can influence gene expression. Early environments with exposures to poverty, chronic adversities, and acutely stressful events have been linked to maladaptive development and compromised health and behavior. Genetic differences can impart either enhanced or blunted susceptibility to the effects of such pathogenic environments. However, largely missing from present discourse regarding G-E interplay is the role of time, a "third factor" guiding the emergence of complex developmental endpoints across different scales of time. Trajectories of development increasingly appear best accounted for by a complex, dynamic interchange among the highly linked elements of genes, contexts, and time at multiple scales, including neurobiological (minutes to milliseconds), genomic (hours to minutes), developmental (years and months), and evolutionary (centuries and millennia) time. This special issue of PNAS thus explores time and timing among G-E transactions: The importance of timing and timescales in plasticity and critical periods of brain development; epigenetics and the molecular underpinnings of biologically embedded experience; the encoding of experience across time and biological levels of organization; and gene-regulatory networks in behavior and development and their linkages to neuronal networks. Taken together, the collection of papers offers perspectives on how G-E interplay operates contingently within and against a backdrop of time and timescales.


Assuntos
Interação Gene-Ambiente , Animais , Evolução Biológica , Epigênese Genética , Regulação da Expressão Gênica , Humanos , Tempo
10.
PLoS One ; 15(9): e0239217, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32941494

RESUMO

BACKGROUND: Worldwide population has been increasingly exposed to ultra-processed foods, which are associated with obesity. Adolescence is a transition period of life and WHO recommends the surveillance of risk factors to the adolescents' health, such as diet, because experiences in this phase can result in health risks. OBJECTIVE: To assess the trends in food consumption of adolescents from Brazilian capitals according to sociodemographic variables, based on data from the National Survey of School Health (PeNSE). METHODS: Data from in 2009, 2012 and 2015 of a total of 173,310 9th graders enrolled in public and private schools in Brazilian capitals and in the Federal District were assessed. Food consumption was assessed from regular consumption (five or more times a week) of healthy eating markers (beans; vegetables; fruit) and unhealthy eating markers (sweets; soft drinks; fried salty snacks). For sociodemographic variables, we considered macro regions; age; race/ skin color; gender; school administrative status. We assessed these markers trends for the population and, additionally, the analyses were stratified by gender, race/ skin color, and school administrative status. Statistical significance of the temporal trends was assessed by linear regression model. RESULTS: Over six years, three types of change in Brazilian adolescents' diet were observed: decreasing regular consumption of beans, sweets and soft drinks, increasing regular consumption of vegetables, and stable consumption of fruit and fried salty snacks. CONCLUSION: Brazilian adolescents' diet composition has changed in a short period, and therefore it is necessary to monitor it to propose actions aimed at this public.


Assuntos
Comportamento do Adolescente , Dieta/estatística & dados numéricos , Comportamento Alimentar , Adolescente , Brasil , Bebidas Gaseificadas/estatística & dados numéricos , Dieta/ética , Fast Foods/estatística & dados numéricos , Feminino , Humanos , Masculino , Fatores Sexuais , Fatores Socioeconômicos , Tempo
11.
J Prev Med Public Health ; 53(4): 228-232, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32752591

RESUMO

Coronavirus disease 2019 (COVID-19) is inflicting a brutal blow on humankind, and no corner of the world has been exempted from its wrath. This study analyzes the chief control measures and the distinctive features of the responses implemented by Korea and the United States to contain COVID-19 with the goal of extracting lessons that can be applied globally. Even though both nations reported their index cases on the same day, Korea succeeded in flattening the curve, with 10 752 cases as of April 28, 2020, whereas the outbreak skyrocketed in the United States, which had more than 1 million cases at the same time. The prudent and timely execution of control strategies enabled Korea to tame the spread of the virus, whereas the United States paid a major price for its delay, although it is too early to render a conclusive verdict. Information pertaining to the number of people infected with the virus and measures instituted by the government to control the spread of COVID-19 was retrieved from the United States Centers for Disease Control and Prevention and the Korea Centers for Disease Control and Prevention websites and press releases. Drawing lessons from both nations, it is evident that the resolution to the COVID-19 pandemic lies in the prudent usage of available resources, proactive strategic planning, public participation, transparency in information sharing, abiding by the regulations that are put into place, and how well the plan of action is implemented.


Assuntos
Betacoronavirus , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/prevenção & controle , Pandemias/prevenção & controle , Pneumonia Viral/epidemiologia , Pneumonia Viral/prevenção & controle , Saúde Pública/métodos , Quarentena/estatística & dados numéricos , Surtos de Doenças/estatística & dados numéricos , Humanos , Pandemias/estatística & dados numéricos , República da Coreia/epidemiologia , Tempo , Estados Unidos/epidemiologia
13.
Proc Natl Acad Sci U S A ; 117(35): 21230-21234, 2020 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-32817508

RESUMO

A foundation of human cognition is the flexibility with which we can represent any object as either a unique individual (my dog Fred) or a member of an object category (dog, animal). This conceptual flexibility is supported by language; the way we name an object is instrumental to our construal of that object as an individual or a category member. Evidence from a new recognition memory task reveals that infants are sensitive to this principled link between naming and object representation by age 12 mo. During training, all infants (n = 77) viewed four distinct objects from the same object category, each introduced in conjunction with either the same novel noun (Consistent Name condition), a distinct novel noun for each object (Distinct Names condition), or the same sine-wave tone sequence (Consistent Tone condition). At test, infants saw each training object again, presented in silence along with a new object from the same category. Infants in the Consistent Name condition showed poor recognition memory at test, suggesting that consistently applied names focused them primarily on commonalities among the named objects at the expense of distinctions among them. Infants in the Distinct Names condition recognized three of the four objects, suggesting that applying distinct names enhanced infants' encoding of the distinctions among the objects. Infants in the control Consistent Tone condition recognized only the object they had most recently seen. Thus, even for infants just beginning to speak their first words, the way in which an object is named guides infants' encoding, representation, and memory for that object.


Assuntos
Memória/fisiologia , Rememoração Mental/fisiologia , Reconhecimento Psicológico/fisiologia , Cognição/fisiologia , Feminino , Humanos , Lactente , Idioma , Masculino , Nomes , Reconhecimento Visual de Modelos/fisiologia , Tempo
14.
Proc Natl Acad Sci U S A ; 117(33): 19873-19878, 2020 08 18.
Artigo em Inglês | MEDLINE | ID: mdl-32727898

RESUMO

Following the April 16, 2020 release of the Opening Up America Again guidelines for relaxing coronavirus disease 2019 (COVID-19) social distancing policies, local leaders are concerned about future pandemic waves and lack robust strategies for tracking and suppressing transmission. Here, we present a strategy for triggering short-term shelter-in-place orders when hospital admissions surpass a threshold. We use stochastic optimization to derive triggers that ensure hospital surges will not exceed local capacity and lockdowns are as short as possible. For example, Austin, Texas-the fastest-growing large city in the United States-has adopted a COVID-19 response strategy based on this method. Assuming that the relaxation of social distancing increases the risk of infection sixfold, the optimal strategy will trigger a total of 135 d (90% prediction interval: 126 d to 141 d) of sheltering, allow schools to open in the fall, and result in an expected 2,929 deaths (90% prediction interval: 2,837 to 3,026) by September 2021, which is 29% of the annual mortality rate. In the months ahead, policy makers are likely to face difficult choices, and the extent of public restraint and cocooning of vulnerable populations may save or cost thousands of lives.


Assuntos
Infecções por Coronavirus/epidemiologia , Modelos Logísticos , Pneumonia Viral/epidemiologia , Quarentena/métodos , Distância Social , Capacidade de Resposta ante Emergências/organização & administração , Infecções por Coronavirus/economia , Infecções por Coronavirus/prevenção & controle , Efeitos Psicossociais da Doença , Hospitalização/economia , Hospitalização/estatística & dados numéricos , Humanos , Pandemias/economia , Pandemias/prevenção & controle , Pneumonia Viral/economia , Pneumonia Viral/prevenção & controle , Quarentena/economia , Quarentena/organização & administração , Capacidade de Resposta ante Emergências/economia , Tempo , Populações Vulneráveis
15.
Nat Commun ; 11(1): 3534, 2020 07 15.
Artigo em Inglês | MEDLINE | ID: mdl-32669545

RESUMO

Dual-process models of altruistic choice assume that automatic responses give way to deliberation over time, and are a popular way to conceptualize how people make generous choices and why those choices might change under time pressure. However, these models have led to conflicting interpretations of behaviour and underlying psychological dynamics. Here, we propose that flexible, goal-directed deployment of attention towards information priorities provides a more parsimonious account of altruistic choice dynamics. We demonstrate that time pressure tends to produce early gaze-biases towards a person's own outcomes, and that individual differences in this bias explain how individuals' generosity changes under time pressure. Our gaze-informed drift-diffusion model incorporating moment-to-moment eye-gaze further reveals that underlying social preferences both drive attention, and interact with it to shape generosity under time pressure. These findings help explain existing inconsistencies in the field by emphasizing the role of dynamic attention-allocation during altruistic choice.


Assuntos
Altruísmo , Atenção , Comportamento de Escolha , Encéfalo/fisiologia , Simulação por Computador , Fixação Ocular , Teoria do Jogo , Humanos , Individualidade , Motivação , Distribuição Normal , Comportamento Social , Software , Tempo
18.
Am J Crit Care ; 29(5): e104-e107, 2020 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-32666088

RESUMO

BACKGROUND: In response to the coronavirus pandemic, New York State mandated that all hospitals double the capacity of their adult intensive care units In this facility, resources were mobilized to increase from 104 to 283 beds. OBJECTIVE: To create and implement a 3-hour curriculum to prepare several hundred non-critical care staff nurses to manage critically ill patients with coronavirus disease 2019. METHODS: Critical care nursing leaders and staff developed and implemented a flexible critical care nursing curriculum tailored to the diverse experience, expertise, and learning needs of non-critical care nursing staff who were being redeployed to critical care units during the surge response to the pandemic. Curricular elements included respiratory failure and ventilator management, shock and hemodynamics, pharmacotherapy for critical illnesses, and renal replacement therapy. A skills station allowed hands-on practice with common critical care equipment. RESULTS: A total of 413 nurses completed training within 10 days. As of June 2020, 151 patients with coronavirus disease 2019 still required mechanical ventilation at our institution, and 7 of 10 temporary intensive care units remained operational. Thus most of the nurses who received this training continued to practice critical care. A unique feature of this curriculum was the tailored instruction, adapted to learners' needs, which improved the efficiency of content delivery. CONCLUSIONS: Program evaluation is ongoing. As recovery and restoration proceed and normal operations resume, detailed feedback from program participants and patient care managers will help the institution maintain high operational readiness should a second wave of critically ill patients with coronavirus disease 2019 be admitted.


Assuntos
Betacoronavirus , Infecções por Coronavirus/enfermagem , Enfermagem de Cuidados Críticos/educação , Currículo , Educação em Enfermagem/métodos , Pneumonia Viral/enfermagem , Humanos , New York , Pandemias , Tempo
19.
Neurology ; 95(14): e1971-e1978, 2020 10 06.
Artigo em Inglês | MEDLINE | ID: mdl-32690797

RESUMO

OBJECTIVE: To assess the long-term safety and tolerability and to monitor benefits of extended use of bimagrumab in individuals with sporadic inclusion body myositis (sIBM) who completed a single-dose core study. METHODS: In this multicenter, open-label extension study, 10 adults received bimagrumab 10 mg/kg IV every 4 weeks up to 2 years (104 weeks). Safety (primary endpoint) was assessed by recording adverse events (AEs). Clinical benefits were assessed by changes from baseline in thigh muscle volume (TMV), lean body mass (LBM), 6-minute walk distance (6MWD), handgrip, and quadriceps strength. RESULTS: Participants had a mean age of 70.1 (SD 10.4) years. All participants (n = 10) discontinued the treatment due to early termination of the study (n = 7) or AEs (n = 3; myocardial infarction, esophageal carcinoma, and dementia, none of which were treatment related). The most common AEs were muscle spasms and falls (both 9 of 10, 90%), followed by diarrhea (6 of 10, 60%) and acne and skin eruption (both 5 of 10, 50%). At weeks 8 and 16, mean TMV increased from baseline by 4.1% (SD 4.3%) and 4.5% (SD 6.3%). Mean LBM increased from baseline and was sustained at 6.9% (SD 3.9%) at week 76. Means of 6MWD showed a progressive decline from baseline to week 76, during which there was a modest numerical increase in handgrip strength and no significant changes in quadriceps strength. CONCLUSIONS: Long-term treatment up to 2 years with bimagrumab had a good safety profile and was well tolerated in individuals with sIBM. An increase in muscle mass was noted on a group level; however, there was no evidence of clinical improvement. CLINICALTRIALSGOV IDENTIFIER: NCT02250443. CLASSIFICATION OF EVIDENCE: This study provides Class IV evidence that for patients with sIBM, long-term bimagrumab treatment was safe and well tolerated and did not lead to functional improvement.


Assuntos
Anticorpos Monoclonais Humanizados/uso terapêutico , Miosite de Corpos de Inclusão/tratamento farmacológico , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Força Muscular/efeitos dos fármacos , Tempo , Resultado do Tratamento
20.
Environ Res ; 189: 109941, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32678728

RESUMO

The coronavirus (COVID-19) epidemic reported for the first time in Wuhan, China at the end of 2019, which has caused 4648 deaths in China as of July 10, 2020. This study explored the temporal correlation between the case fatality rate (CFR) of COVID-19 and particulate matter (PM) in Wuhan. We conducted a time series analysis to examine the temporal day-by-day associations. We observed a higher CFR of COVID-19 with increasing concentrations of inhalable particulate matter (PM) with an aerodynamic diameter of 10 µm or less (PM10) and fine PM with an aerodynamic diameter of 2.5 µm or less (PM2.5) in the temporal scale. This association may affect patients with mild to severe disease progression and affect their prognosis.


Assuntos
Poluição do Ar , Infecções por Coronavirus/mortalidade , Material Particulado/análise , Pneumonia Viral/mortalidade , Poluentes Atmosféricos/análise , Betacoronavirus , China/epidemiologia , Humanos , Pandemias , Tempo
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