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1.
Stud Health Technol Inform ; 264: 611-615, 2019 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-31437996

RESUMO

Neonatal screening and ongoing follow-up of children with sickle cell disease are essential to reduce the mortality caused by this disease. To ensure care continuity, it is essential to include in the patient's record the history and details of biological tests. Thus, it is necessary to provide a Laboratory Information System for electronic management of biological test prescription and results, and the laboratory system must integrate well with Health Information Systems. In this paper, we propose a Laboratory Information System for the management of biological tests for the neonatal screening and healthcare of sickle cell disease in Senegal.


Assuntos
Anemia Falciforme , Sistemas de Informação em Laboratório Clínico , Testes Hematológicos , Humanos , Recém-Nascido , Triagem Neonatal , Senegal
3.
Recurso na Internet em Português | LIS - Localizador de Informação em Saúde | ID: lis-LISBR1.1-46621

RESUMO

O diagnóstico precoce, o tratamento adequado e o acompanhamento médico de algumas doenças podem evitar a morte, deficiências e proporcionar melhor qualidade de vida aos recém-nascidos. Saiba mais sobre o fortalecimento do cuidado aos recém-nascidos e as ações desenvolvidas aqui.


Assuntos
Programas Nacionais de Saúde , Triagem Neonatal , Recém-Nascido , Indicadores de Morbimortalidade , Sistema Único de Saúde , Doenças do Recém-Nascido
4.
Zhonghua Er Ke Za Zhi ; 57(6): 494-496, 2019 06 02.
Artigo em Chinês | MEDLINE | ID: mdl-31216812
5.
Rev Inst Med Trop Sao Paulo ; 61: e30, 2019 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-31241659

RESUMO

Toxoplasma gondii can cross the placental barrier, causing fetal infection with potentially severe sequelae. The aim of this study was to evaluate whether the serological screening for toxoplasmosis should be included in the basic neonatal heel prick test in order to establish criteria for the confirmation and/or exclusion of the diagnosis of congenital infection in newborns treated at three public health units in the metropolitan region of Goiania, Goias State, Brazil. Blood samples were collected on filter paper from newborns and later, peripheral blood samples from the mothers and their respective children were obtained to confirm or exclude the diagnosis of suspected congenital infection, by means of an enzyme-linked immunosorbent assay (IgM and IgG) and a polymerase chain reaction assay. From a total of 1,159 blood samples collected on filter paper, 43.92% were reactive to IgG and 0.17% to anti-T. gondii IgM and IgG. One hundred and twenty-seven paired samples (mother and child) were collected following consensual protocols for peripheral blood collection. Results obtained from the filter paper and peripheral blood of the newborns were 90.55% concordant. A comparison of the mother and child blood test results showed agreement regarding the detection of IgG in 90.48% of the samples. The parasite DNA was detected in the peripheral blood of one child. In view of the results obtained in this study, the inclusion of the serological screening for toxoplasmosis in the newborn heel prick test proved to be effective for the early detection of congenital T. gondii infection.


Assuntos
Triagem Neonatal/métodos , Complicações Infecciosas na Gravidez/sangue , Complicações Infecciosas na Gravidez/diagnóstico , Toxoplasma/microbiologia , Toxoplasmose Congênita/sangue , Toxoplasmose Congênita/diagnóstico , Anticorpos Antiprotozoários/sangue , Brasil , Feminino , Doenças Fetais , Humanos , Imunoglobulina A/sangue , Imunoglobulina G/sangue , Imunoglobulina M/sangue , Recém-Nascido , Transmissão Vertical de Doença Infecciosa , Reação em Cadeia da Polimerase , Gravidez , Complicações Infecciosas na Gravidez/genética , Estudos Prospectivos , Toxoplasma/genética , Toxoplasmose Congênita/genética
6.
Cent Eur J Public Health ; 27(2): 153-159, 2019 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-31241292

RESUMO

OBJECTIVES: Presymptomatic detection of patients with rare diseases (RD), defined by a population frequency less than 1 : 2,000, is the task of newborn screening (NBS). In the Czech Republic (CZ), currently eighteen RD are screened: phenylketonuria/hyperphenylalaninemia (PKU/HPA), congenital hypothyroidism (CH), congenital adrenal hyperplasia (CAH), cystic fibrosis (CF), medium chain acyl-CoA dehydrogenase deficiency (MCADD), long chain 3-hydroxyacyl-CoA dehydrogenase deficiency (LCHADD), very long chain acyl-CoA dehydrogenase deficiency (VLCADD), carnitine palmitoyl transferase I and II deficiency (CPTID, CPTIID), carnitine-acylcarnitine translocase deficiency (CACTD), maple syrup urine disease (MSUD), glutaric aciduria type I (GA I), isovaleryl-CoA dehydrogenase deficiency (IVA), argininemia (ARG), citrullinemia (CIT), biotinidase deficiency (BTD), cystathionine beta-synthase-deficient homocystinuria (CBSD HCU), and methylenetetrahydrofolate reductase deficiency homocystinuria (MTHFRD HCU). The aim was to analyze the prevalence of RD screened by NBS in CZ. METHODS: We examined the NBS programme in CZ from 1 January 2010 to 31 December 2017, which covered 888,891 neonates. Dried blood spots were primarily analyzed using fluorescence immuno-assay, tandem mass spectrometry and fluorimetry. RESULTS: The overall prevalence of RD among the neonate cohort was 1 : 1,043. Individually, 1 : 2,877 for CH, 1 : 5,521 for PKU/HPA, 1 : 6,536 for CF (1 : 5,887 including false negative patients), 1 : 12,520 for CAH, 1 : 22,222 for MCADD, 1 : 80,808 for LCHADD, 1 : 177,778 for GA I, 1 : 177,778 for IVA, 1 : 222,223 for VLCADD, 1 : 296,297 for MSUD, 1 : 8,638 for BTD, and 1 : 181,396 for CBSD HCU. CONCLUSIONS: The observed prevalence of RD, based on NBS, corresponds to that expected, more precisely it was higher for BTD and lower for MSUD, IVA, CBSD HCU, MCADD and VLCADD. Early detection of rare diseases by means of NBS is an effective secondary prevention tool.


Assuntos
Triagem Neonatal/métodos , Doenças Raras/epidemiologia , Biomarcadores/sangue , República Tcheca/epidemiologia , Fluorometria , Humanos , Recém-Nascido , Doenças Raras/sangue , Espectrometria de Massas em Tandem
7.
Lima; Perú. Ministerio de Salud; 20190600. 37 p. tab, ilus.
Monografia em Espanhol | LILACS, LIPECS | ID: biblio-1005180

RESUMO

Contribuir a la conservación de la salud de la población infantil y prevenir precoz y oportunamente la morbilidad, discapacidad y mortalidad mediante la detección de alteraciones metabólicas, auditivas y visuales en la etapa neonatal, favoreciendo el adecuado desarrollo infantil temprano en el país.


Assuntos
Desenvolvimento Infantil , Triagem Neonatal , Normas Técnicas , Serviços de Saúde da Criança
8.
BMC Public Health ; 19(1): 731, 2019 Jun 11.
Artigo em Inglês | MEDLINE | ID: mdl-31185962

RESUMO

BACKGROUND: With Universal Health Coverage and Integrated People-centred Health Care, streamlined health-systems and respectful care are necessary. South Africa has made great strides in prevention of mother-to-child transmission (PMTCT) but with the great burden of HIV, a minimum of birth and 10-week HIV-PCR testing are required for the estimated 360,000 HIV-exposed infants born annually which presents many challenges including delayed results and loss to follow-up. Point-of-care (POC) HIV testing of infants addresses these challenges well and facilitates initiation of HIV-infected infants rapidly after diagnosis for best clinical outcomes. METHODS: Objectives were to determine accuracy, feasibility and acceptability of POC testing compared to standard-of-care (SOC) central-laboratory testing. HIV-exposed infants for birth PCR testing in hospital (n = 323) and follow-up at a primary health care clinic (n = 117) in Durban, South Africa were included. A baseline situational-analysis reviewed registers and phoned mothers of HIV-exposed infants prior to the intervention. An effectiveness-implementation study of the Alere™q HIV-1/2 Detect POC test (heel-prick specimen processed in 50 min) was compared with SOC with questionnaires to mothers and staff. Stata 14 was used for analysis. RESULTS: At baseline 2% of birth HIV tests were missed; only 40% of mothers could be contacted; 17% did not receive birth test result; 19% did not have a 10-week test; 39% had not received the 10-week results. There were 5(1.5%) HIV-infected and 318(98.5%) HIV-negative infants detected in hospital with all clinic babies negative. All positive infants commenced ART before discharge. Ultimately POC and SOC had perfect concordance but for 10 SOC tests researchers actively tracked-down results or repeated tests. Turn around times for SOC tests were on average 8-days (IQR 6-10 days) and for POC testing was 0-days. The POC error-rate was 9,6% with all giving a result when repeated. The majority of mothers (92%) preferred POC testing with 7% having no preference. No staff preferred SOC testing with 79% preferring POC and 21% having no preference. CONCLUSIONS: Point-of-care HIV testing for EID is accurate, feasible and acceptable, with benefits of early ART for all positive infants at birth facilities. We recommend that it be considered best practice for EID. TRIAL REGISTRATION: ISRCTN38911104 registered 9 January 2018 - retrospectively registered.


Assuntos
Infecções por HIV/diagnóstico , HIV , Implementação de Plano de Saúde , Triagem Neonatal/métodos , Sistemas Automatizados de Assistência Junto ao Leito , Diagnóstico Precoce , Feminino , Infecções por HIV/prevenção & controle , Infecções por HIV/transmissão , Humanos , Recém-Nascido , Transmissão Vertical de Doença Infecciosa/prevenção & controle , Masculino , Reação em Cadeia da Polimerase/métodos , Gravidez , Estudos Retrospectivos , África do Sul
9.
Indian J Ophthalmol ; 67(6): 828-833, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124496

RESUMO

Purpose: The purpose was to study the incidence, risk factors, and anatomical outcomes after laser treatment in retinopathy of prematurity (ROP). Methods: A retrospective observational study was carried out. Infants admitted to Neonatal Intensive Care Unit of 12 referral hospitals between April 2016 and September 2017 were screened according to the latest Indian guidelines based on the International Classification of Retinopathy of Prematurity. Results: The incidence of ROP in 1648 eyes screened was 25.36% (418 eyes), out of which high-risk prethreshold ROP (type 1) was observed in 9.95% (164 eyes). Decreased hemoglobin (P < 0.001), oxygen requirement (P = 0.008), and number of blood transfusions (P = 0.037) were significant with type 1 than type 2 (low-risk prethreshold) ROP. Stages 1, 2, and 3 were observed in 82 (32.28%), 154 (60.62%), and 18 (7.08%) eyes, respectively. Aggressive posterior ROP (APROP) was observed in 20.73% eyes with type 1 ROP. Ten eyes showing APROP were treated at an early gestational age of 29 weeks. All infants with type 1 ROP were treated with laser photocoagulation only. Conclusion: One-fourth of the infants showed ROP and one-tenth needed laser photocoagulation, the outcome of which was excellent. Risk factors predisposing to ROP were anemia, high oxygen supplementation, increased number of blood transfusions, and septicemia. ROP screening in infants ≥1700 g birth weight associated with various systemic risk factors may be beneficial in the Indian population.


Assuntos
Unidades de Terapia Intensiva Neonatal , Fotocoagulação a Laser/métodos , Triagem Neonatal/métodos , Retinopatia da Prematuridade/diagnóstico , Acuidade Visual , Feminino , Idade Gestacional , Humanos , Incidência , Índia/epidemiologia , Recém-Nascido , Masculino , Oftalmoscopia/métodos , Retinopatia da Prematuridade/epidemiologia , Retinopatia da Prematuridade/cirurgia , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento
10.
Indian J Ophthalmol ; 67(6): 834-839, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124497

RESUMO

Purpose: The gold standard for evaluating Retinopathy of prematurity (ROP), a potentially blinding disease in preterm babies, is by indirect ophthalmoscopy which is quite subjective. Digital imaging with RetCam, an advanced wide field imaging system is more precise but it is not easily available or affordable. Smartphones are being explored as an alternate cost effective and accessible imaging tool. This is possible because of the good illumination and the built-in high resolution cameras available in modern smartphones. The aim of this study is to illustrate the utility of MII RetCam assisted smartphone based fundus imaging (MSFI) in the documentation and monitoring of ROP. Methods: Single-centre, retrospective observational study of all the preterm babies subjected to MSFI as part of ROP screening from September 2017 to November 2018. iPhone 4S and + 20 Diopter lens attached to the MII RetCam device was used for fundus imaging at baseline and during follow up. The statistical analysis used for the same is the SPSS statistical software. Results: Good quality images of central and peripheral retina could be captured in 33 out of 42 babies (78.57%) with ROP. Serial imaging done in 24 babies with ROP helped in precise monitoring of the disease and planning management. Incidentally detected non-ROP findings were also documented. Unique design of the device enabled imaging by a single examiner. Image database created was useful for academic and counselling purposes. Smaller field images which can cause difficulty in distinguishing the zones is a limitation. Conclusion: MSFI is a potential alternate imaging tool enabling objective documentation and monitoring of ROP in low resource settings.


Assuntos
Triagem Neonatal/métodos , Retinopatia da Prematuridade/diagnóstico , Smartphone , Telemedicina/instrumentação , Desenho de Equipamento , Feminino , Seguimentos , Fundo de Olho , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Valor Preditivo dos Testes , Estudos Retrospectivos
11.
Indian J Ophthalmol ; 67(6): 840-845, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124499

RESUMO

Purpose: To suggest a low cost, non-contact smartphone-based screening system in retinopathy of prematurity (ROP), and to illustrate its potential clinical application as a potential future tool for teleophthalmology. Methods: Neonatal intensive care unit (NICU)-based bedside ROP screening done between January 2018 and May 2018. Documentation of ROP was done by using a smartphone and +40D, +28D, or +20D indirect non-contact condensing lenses. By using the coaxial light source of the phone, this system works as an indirect ophthalmoscope that creates a digital image of the fundus. With smartphone-based camera we extracted high-quality still images extracted from the video clip. Results: Total of 228 eyes of 114 infants screened for ROP between January 2018 and May 2018. Incidence of total ROP was 23.68%, out of which incidence of type 1 ROP was 8.77%. After initial screening with indirect ophthalmoscope, we uesd smartphone imaging to document ROP in 28 eyes out of 55 eyes having ROP. Image quality was good in 89.28% eyes. Field of view vary from 46°, 53°, and 90° with +20D, +28D, and +40D indirect condensing lenses, respectively, which gives excellent images for bedside ROP documentation. Conclusion: The described technique of smartphone fundus photography is a light weight, cost-effective, user friendly, high-quality wide-field fundus photographs for bedside documentation of ROP in NICUs using readily available instruments that are handy and portable with simple power sources. Smartphones has the potential to be operated with only one hand. It can also be used as a future telescreening device.


Assuntos
Unidades de Terapia Intensiva Neonatal , Triagem Neonatal/métodos , Retinopatia da Prematuridade/diagnóstico , Smartphone , Telemedicina/instrumentação , Desenho de Equipamento , Feminino , Seguimentos , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Oftalmoscopia/métodos , Reprodutibilidade dos Testes , Estudos Retrospectivos
12.
Indian J Ophthalmol ; 67(6): 846-853, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124500

RESUMO

Purpose: To use the extent of retinal immaturity at the first visit to predict progression to any stage and treatment-requiring retinopathy of prematurity (ROP). Methods: Retrospective, multicenter, nonrandomized, observational, clinical, validation study. In all, 601 Asian Indian preterm infants born < 2000 g and/or < 34 weeks of gestation completing ROP screening with RetCam images taken during each visit were included. A total of 1202 eyes of these infants were classified into three groups based on the retinal immaturity at the first screening visit into "mild" (Group 1), vessels reaching the posterior boundary of zone 3; "moderate" (Group 2), vessels entering zone 2 anterior; and "severe" (Group 3), vessels in zone 1 or zone 2 posterior. RetCam images at each subsequent visit were evaluated and the proportion of eyes that progressed to Type 1 or Type 2 ROP was correlated with the degree of retinal immaturity. Results: Of the 958 eyes in Group 1, 200 eyes in Group 2, and 44 eyes in Group 3, any stage ROP developed in 15% of eyes in Group 1, 46.5% of eyes in Group 2, and 100% of eyes in Group 3 (P < 0.001). Sixteen of 128 eyes (12.5%), 12 of 72 (16.6%), and 28 of 44 of eyes (63.6%) in Groups 1, 2, and 3, respectively, required treatment (P < 0.001). Conclusion: Retinal immaturity at first screening visit predicts Type 1 and Type 2 ROP. "Severe" immaturity is more likely to progress to "treatment-requiring" disease. This could be a useful tool for prognostication, counseling, and scheduling follow-up.


Assuntos
Triagem Neonatal/métodos , Retina/patologia , Vasos Retinianos/diagnóstico por imagem , Retinopatia da Prematuridade/diagnóstico , Progressão da Doença , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Masculino , Reprodutibilidade dos Testes , Estudos Retrospectivos , Acuidade Visual
13.
Indian J Ophthalmol ; 67(6): 855-859, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124502

RESUMO

Purpose: To evaluate the factors influencing timely versus delayed presentation of preterm babies for ROP evaluation. Methods: Preterm babies (≤35 weeks gestational age, ≤2000 g birth weight) were prospectively included in the study. Timely presentation was defined as babies who presented for the first ROP screening within 30 days of birth and Delayed as more than 30 days of birth. An event survey to assess factors influencing timely vs delayed presentation was administered to parents/guardian of babies after obtaining informed consent. Results: Data of 278 preterm babies (n = 139 timely vs n = 139 delayed presentation) collected in the event surveys were analyzed. The delayed presenters came at a median duration of 6.3 weeks (1st and 3rd quartiles: 5.3 and 9.1) after birth. The odds of any stage of ROP was 2.6 times and the odds of sight threatening ROP was 6.8 times in those presenting delayed compared to those presenting timely. Major Reasons for delayed presentation were not asked to do so/no referral from pediatrician in 64 (46%) participants and unaware of the importance by 46 (33%) participants. Conclusion: Deviation from screening protocol is an important modifiable risk factor in ROP screening. The study findings suggest the need for creating awareness about timely screening and referral guidelines among the pediatricians involved in "care" of preterm infants at risk of developing ROP.


Assuntos
Diagnóstico Precoce , Recém-Nascido Prematuro , Triagem Neonatal/métodos , Retinopatia da Prematuridade/diagnóstico , Estudos Transversais , Seguimentos , Idade Gestacional , Humanos , Incidência , Índia/epidemiologia , Recém-Nascido , Estudos Prospectivos , Retinopatia da Prematuridade/epidemiologia , Centros de Atenção Terciária , Fatores de Tempo
14.
Indian J Ophthalmol ; 67(6): 928-931, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124517

RESUMO

Purpose: To explore the knowledge of retinopathy of prematurity (ROP) and habilitation services for children with visual loss from ROP, among health care professionals (HCPs) involved in care of preterm children and to explore their attitudes and practices in relation to referral for habilitation. Methods: A modified knowledge, attitude and practice questionnaire were administered to ophthalmologists and paediatricians associated with ROP care. Data were collected about their knowledge, beliefs and practices of ROP and referral to rehabilitation facilities. Data were analysed to establish level of knowledge, type of attitude and practices and its association with speciality. Results: Response rate was 78% (25/32). Most (14/25, 56%) were ophthalmologists. All (100%) participants knew that ROP can cause blindness. Knowledge about Indian ROP screening criteria was poor among a third (8/25, 32%), more so in paediatricians (5/11, 45.5%). Most (21/25, 84%) did not have knowledge of what a habilitation service entails and where such facilities are located. More than two-thirds (18/25, 72%) believed that special education should be preferred over inclusive education. Overall, 10/25 (40%) of the HCPs had never referred a child for rehabilitation. More than a half (13/25, 52%) were not confident of counselling parents of blind children. All agreed that rehabilitation services are not part of but should be included in medical curriculum. Conclusion: Indian guidelines for ROP screening are not universally known among HCPs. Educating medical undergraduates, providing counselling training to professionals and integration of rehabilitation into the health system will ensure continuity of care for children with visual loss and their families.


Assuntos
Cegueira/reabilitação , Conhecimentos, Atitudes e Prática em Saúde , Triagem Neonatal/métodos , Pediatras/normas , Retinopatia da Prematuridade/reabilitação , Acuidade Visual , Adolescente , Adulto , Distribuição por Idade , Cegueira/epidemiologia , Cegueira/etiologia , Criança , Pré-Escolar , Feminino , Idade Gestacional , Humanos , Índia/epidemiologia , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Retinopatia da Prematuridade/complicações , Retinopatia da Prematuridade/fisiopatologia , Fatores de Risco , Inquéritos e Questionários , Adulto Jovem
15.
Indian Pediatr ; 56(4): 281-286, 2019 04 15.
Artigo em Inglês | MEDLINE | ID: mdl-31064895

RESUMO

OBJECTIVE: To determine an appropriate cut-off of capillary Thyroid stimulating hormone (TSH) for congenital hypothyroidism. STUDY DESIGN: Cross-sectional. PARTICIPANTS: 174,000 neonates born in different hospitals of Delhi, India, from November 2014 to October 2016. MAIN OUTCOME MEASURES: Correlation between initial and repeat capillary TSH level and subsequent venous free thyroxine (fT4) level. RESULTS: 102 newborns with initial/ repeat capillary TSH level of ≥20 mIU/L (n=174) were confirmed to have congenital hypothyroidism at mean (SD) age of 5 (4) days. A good correlation between capillary TSH level and confirmatory venous fT4 level and postnatal age of sampling was obtained (r -0.6, -0.4). The area under the ROC curve (AUC) was 0.81 (95%CI 0.75 to 0.88), indicating referral capillary TSH level of 20 mIU/L to be a good predictor of subsequent high venous TSH level. CONCLUSIONS: A cut off of ≥20 mIU/L for capillary TSH screening beyond 24 hours of life is optimal in the Indian setting for deciding further recall and workup, keeping a balance between sensitivity and recall rate.


Assuntos
Hipotireoidismo Congênito/sangue , Hipotireoidismo Congênito/diagnóstico , Triagem Neonatal/métodos , Triagem Neonatal/normas , Tireotropina/sangue , Teste em Amostras de Sangue Seco , Humanos , Índia , Recém-Nascido , Curva ROC , Valores de Referência
18.
Indian J Ophthalmol ; 67(6): 726-731, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124480

RESUMO

Many of the causes of childhood blindness are avoidable, being either preventable or treatable. Retinopathy of prematurity (ROP) remains one of the most preventable causes of childhood blindness worldwide. Currently, India is facing the third epidemic of ROP. In India, the health system involving the mother and child health services needs to be strengthened with a policy to cover the existing inadequacies in neonatal care and implementation of program covering newborn, especially premature. The access, availability, and affordability of services related to the care of premature babies need strengthening in India. ROP-trained ophthalmologists and neonatal care pediatricians and a professional togetherness is a big issue. Inadequacies in awareness of ROP among the parents, health care workers, counsellors add up to the problem. Community-based health workers such as Accredited Social Health Activist are a good dependable force in India and are needed to be trained in awareness and establishing a proper identification for prompt referral. ROP prevention needs a multidisciplinary team approach. ROP management stands as a good example of all the strategies for prevention, which includes primary prevention (improving obstetric and neonatal care), secondary prevention (screening and treatment programs), and tertiary prevention (treating complications and rehabilitation to reduce disability). Given its demographic and cultural diversity, India faces numerous challenges, with significant rural-urban, poor-rich, gender, socioeconomic, and regional differences. So, we need to gear up to face the present challenge of the third epidemic of ROP and prevent ROP-related childhood blindness as it is the need of the hour.


Assuntos
Cegueira , Triagem Neonatal/métodos , Retinopatia da Prematuridade/epidemiologia , Cegueira/epidemiologia , Cegueira/etiologia , Cegueira/prevenção & controle , Humanos , Incidência , Índia/epidemiologia , Recém-Nascido , Prevalência , Retinopatia da Prematuridade/complicações , Retinopatia da Prematuridade/diagnóstico
19.
Indian J Ophthalmol ; 67(6): 811-815, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124492

RESUMO

Purpose: More than 3.5 million Syrians came to Turkey seeking refuge and over 470,000 Syrian infants were born since the start of the civil war in 2011. Our aim is to compare the incidence of retinopathy of prematurity (ROP) between Syrian refugees and Turkish citizens. Methods: This multicenter, retrospective study was conducted in Gaziantep University, Faculty of Medicine and Gaziantep Children's Hospital in Turkey. We included the data of patients who were screened for ROP between July 2015 and June 2017. Results: The above-mentioned data of 906 Turkish infants and 199 Syrian infants were included in this study. Mean gestational ages (GAs) were (32.9 ± 2.7) and (32.1 ± 2.8) weeks as well as mean birth weights (BWs) were (1937.5 ± 582.9) and (1696.8 ± 485.5) g, in Turkish and Syrian infants, respectively. GA and BW were significantly lower in Syrian infants while time spent in neonatal intensive care unit was significantly higher. The zone of ROP was lower in the Syrian infants in the first examination and for the most advanced ROP (P = 0.001). Any stage ROP was present in 392 (43.3%) and 81 (40.7%) patients in Turkish and Syrian population, respectively (P = 0.490). The number of patients who required treatment for ROP were 95 (10.5%) and 20 (10.1%) in Turkish and Syrian groups, respectively (P = 0.882). Conclusion: Our findings showed that refugee infants had lower BW and GA than native population but the incidence of ROP did not differ between them. Psychosocial stress is an important risk factor for women at reproductive age as it increases the incidence of prematurity. Additional care and psychological support must be given to refugees during perinatal period to decrease the risk of premature birth.


Assuntos
Refugiados , Retinopatia da Prematuridade/etnologia , Feminino , Idade Gestacional , Humanos , Incidência , Recém-Nascido , Masculino , Triagem Neonatal , Oftalmoscopia , Prognóstico , Retinopatia da Prematuridade/diagnóstico , Estudos Retrospectivos , Fatores de Risco , Síria/etnologia , Turquia/epidemiologia , Seleção Visual
20.
Indian J Ophthalmol ; 67(6): 816-818, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-31124493

RESUMO

Purpose: Retinopathy of prematurity (ROP) is now emerging as one of the major causes of preventable childhood blindness. The proportion of preterm babies has increased dramatically over the past decade. Our study aims to emphasize the need for ROP screening and management services in these preterm infants. Methods: ICD-coded medical records of children less than 10 years of age presenting to a subspecialty eye hospital from 2000 to 2017 were reviewed. ROP, congenital cataract, congenital glaucoma, and vitamin A deficiency were the most common diagnoses. We evaluated the trend of these diseases from 2000 to 2017. Results: Our data suggested a 20-fold increase in the attendance of children with a diagnosis of ROP who now make over 2% of outpatient children. Vitamin A deficiency has declined over time whereas cataract and glaucoma have remained stable. Conclusion: Our data indicate a need to scale up ROP screening integrated with neonatal care, as well as to build capacity for the treatment of acute and late-stage ROP in India.


Assuntos
Cegueira/epidemiologia , Triagem Neonatal/métodos , Retinopatia da Prematuridade/epidemiologia , Medição de Risco/métodos , Centros de Atenção Terciária/estatística & dados numéricos , Acuidade Visual , Cegueira/etiologia , Criança , Pré-Escolar , Feminino , Idade Gestacional , Humanos , Incidência , Índia/epidemiologia , Lactente , Recém-Nascido , Masculino , Prevalência , Retinopatia da Prematuridade/complicações , Retinopatia da Prematuridade/diagnóstico , Estudos Retrospectivos , Fatores de Risco
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