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1.
Environ Monit Assess ; 192(10): 667, 2020 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-33006063

RESUMO

Dental prosthesis laboratories (DPLs) are among the workplaces where predominantly manual production takes place. In such working environments, during the manual manufacturing process, which involves fine smoothing and polishing of dental prostheses, fine particulate matter is released into the ambient air. In this study, the particulate matter (PM) concentrations and elemental content of the fine particles in the working ambient air were identified in six DPLs in Kocaeli, Turkey. PM2.5 mass concentrations, measured in all the DPLs, ranged between 80.8 and 1645 µg/m3 (mean 414 ± 406). As a result of the analyses performed with an ICP-MS device (Perkin Elmer Elan®DRC-e), trace elements of Be, Cd, Hg, and, notably, Co, Cr, Mo, and Ni were found. The researchers calculated the excess lifetime cancer risks and total hazard indexes. The average total cancer risk for all the DPLs was 8 × 10-3, which is higher than the acceptable limit of 1.0 × 10-6, and the total hazard index was 187, which is greater than the acceptable limit of 1.0. Considering these high-level risks, the study concluded that there is a need for new production methods, and strict application of occupational health and safety measures, to reduce the fine particle exposure of the workers in the laboratories. In addition, there are prescribed limit values for particulate matter only for respirable particles in working environments. The establishment of limit values, especially for PM2.5 concentrations, is important for the protection of the health of the employees.


Assuntos
Prótese Dentária , Exposição Ocupacional , Monitoramento Ambiental , Humanos , Material Particulado/análise , Turquia
2.
Ann Agric Environ Med ; 27(3): 481-484, 2020 Sep 11.
Artigo em Inglês | MEDLINE | ID: mdl-32955233

RESUMO

INTRODUCTION AND OBJECTIVE: Hepatitis A Virus (HAV), reportedly the most common cause of acute viral hepatitis in developing countries, infects millions of people worldwide each year. The aim of the study is to investigate the seropositivity of anti-hepatitis A virus (HAV) IgG and IgM in all age groups in Erzurum, and to determine the effect of various factors such as age, gender, climatic conditions and HAV vaccination (included in 2012 in the National Immunization Schedule on seroprevalence) on the seropositivity. MATERIAL AND METHODS: The serological results of 25,007 individuals referred to Erzurum Public Health Microbiology Laboratory between January 2015 - December 2018 were retrospectively reviewed to test for the presence of anti-HAV IgG and IgM. The patient ages were 0-93 years. Serum samples were analyzed by ELISA. S/CO values of ≥1.00 and >1.21 were considered positive for anti-HAV IgG and IgM, respectively; results below this value were considered negative. RESULTS: Anti-HAV IgG and IgM seropositivities were 87.3% and 0.2%, respectively. Anti-HAV IgG prevalence - 88.5% and 86.4%, anti-HAV IgM positivity - 0.1% and 0.3% in men and women. Anti-HAV IgG seroprevalence - 87%, 73.2%, 58.7%, 75.2%, 86.1%, 89.8%, 96.1%, 99.1%, 99.1% and 99.3%, respectively, at 0-4, 5-9 10-14, 15-19, 20-24, 25-29, 30-39, 40-49, 50-59 and >60 age groups. Anti-HAV IgM seropositivity - 0, 0.1%, 0.7%, 0.7%, 0.3%, 0, 0.1%, 0.2%, 0.1%, and 0.2%, respectively, in the same age groups. Anti-HAV IgM positivity was the highest in November - 36(0.97%. CONCLUSIONS: In Erzurum, anti-HAV IgG prevalence is tremendously high, whereas prevalence of anti-HAV IgM is exceptionally low, especially in the paediatric age group. Therefore, HAV vaccine is provided free of charge in Turkey, including Erzurum, since 2012.


Assuntos
Vírus da Hepatite A/isolamento & purificação , Hepatite A/epidemiologia , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Feminino , Anticorpos Anti-Hepatite A/sangue , Humanos , Lactente , Recém-Nascido , Masculino , Pessoa de Meia-Idade , Prevalência , Estudos Retrospectivos , Estudos Soroepidemiológicos , Turquia/epidemiologia , Adulto Jovem
3.
Environ Monit Assess ; 192(10): 638, 2020 Sep 14.
Artigo em Inglês | MEDLINE | ID: mdl-32924079

RESUMO

Surface water is one of the primary sources for drinking, irrigation, and industrial activities in Ergene River, Turkey. However, its quality has deteriorated due to the point and non-point pollution sources. Therefore, an appropriate assessment of surface water quality is very important. Water quality classification is calculated separately for each quality parameter in Turkey. An overall assessment of surface water quality is essential for water management. In this study, self-organizing maps (SOMs) and fuzzy C-means clustering (FCM) methods have been used for assessing surface water quality in the Ergene River. Seven water quality parameters have been considered as important indicators to evaluate water quality status in 7 observation points located in the river, covering the period from 1985 to 2013.


Assuntos
Rios , Qualidade da Água , Análise por Conglomerados , Monitoramento Ambiental , Turquia
5.
Croat Med J ; 61(4): 319-325, 2020 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-32881429

RESUMO

AIM: To assess the relationship between Helicobacter pylori (H. pylori) infection and atrophic gastritis (AG) and intestinal metaplasia (IM) development and to assess the rate of dysplasia or gastric cancer development in patients with AG and/or IM. METHODS: This retrospective endoscopic follow-up study enrolled 2214 patients. The patients were followed for at least five years between 2007 and 2017 at the Department of Endoscopy at Antalya Ataturk Government Hospital. The results of third-year and five-year surveillance biopsy were assessed. RESULTS: The mean follow-up time was 7.77 ± 2.78 years. H. pylori was histologically assessed in 1417 (64.6%) patients. Of 198 patients with severe H. pylori infection, 32 (16%) and 139 (70.3%) developed extensive AG and extensive IM, respectively. There was a significant relationship between H. pylori density and AG and IM degrees. High grade dysplasia, early gastric cancer, and advanced gastric cancer were diagnosed in 73 patients with median age 58.2 (28-80) years, and the incidence rate was 3.29% (73/2214). The annual incidence of gastric neoplastic lesions was 0.46% in total, 0.08% for early GC, and 0.02% for advanced gastric cancer. CONCLUSIONS: H. pylori infection has an important role in the development of AG and IM. H. pylori density is directly related to atrophy and metaplasia degree.


Assuntos
Gastrite Atrófica/epidemiologia , Infecções por Helicobacter/epidemiologia , Lesões Pré-Cancerosas/epidemiologia , Neoplasias Gástricas/epidemiologia , Adulto , Idoso , Idoso de 80 Anos ou mais , Biópsia , Endoscopia Gastrointestinal , Feminino , Seguimentos , Mucosa Gástrica/patologia , Gastrite Atrófica/microbiologia , Gastrite Atrófica/patologia , Infecções por Helicobacter/diagnóstico , Infecções por Helicobacter/microbiologia , Helicobacter pylori , Humanos , Incidência , Masculino , Metaplasia/patologia , Pessoa de Meia-Idade , Lesões Pré-Cancerosas/microbiologia , Lesões Pré-Cancerosas/patologia , Estudos Retrospectivos , Fatores de Risco , Neoplasias Gástricas/microbiologia , Neoplasias Gástricas/patologia , Turquia/epidemiologia
6.
Soc Work Public Health ; 35(7): 579-589, 2020 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-32970540

RESUMO

The objective of this study; is to find out the sensitivity, the concern that are created by the Covid-19 pandemic on the Syrian refugees, who live in Kilis province of Turkey and have different life standards and status and to find out their possibilities and attitudes of prevention from and combating the pandemic. The data of the study were collected between 12-16 April 2020 by applying a questionnaire on 414 refugees. According to the study results, it has been discovered that the refugees have concerns about Covid-19 and their insensitivity levels are low. It has been seen that there is a group who are not aware of the seriousness of the pandemic, who do not have enough information about the pandemic and cannot reach personal protective equipment (such as masks, gloves). In general, in the fight against pandemic; the levels of refugees' following the rules and their finding the decisions taken and implemented proper, can be defined as close to each other and good.


Assuntos
Infecções por Coronavirus/prevenção & controle , Pandemias/prevenção & controle , Pneumonia Viral/prevenção & controle , Refugiados , Adolescente , Adulto , Betacoronavirus , Infecções por Coronavirus/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pneumonia Viral/epidemiologia , Síria/etnologia , Turquia/epidemiologia
7.
Soc Work Public Health ; 35(7): 603-616, 2020 09 01.
Artigo em Inglês | MEDLINE | ID: mdl-32970545

RESUMO

The uncertainty which is threatening and stressful prevents a person's perception of control and leads to maladaptive psychological reactions such as anxiety. We aimed to define the relationship between the state/trait anxiety levels and perceived social support in the COVID-19 pandemic as a global crisis and stressor. Our main hypothesis was that perceived social support would negatively affect the levels of anxiety. A cross-sectional community-based study was carried out using the relational screening model. The data were collected between March 20 and April 15, 2020, by using an online survey (N = 630). Anxiety levels of individuals, particularly the state anxiety were high during the pandemic. Also, perceived social support and state/trait anxiety levels were analyzed for various variable categories. Anxiety levels decreased significantly when perceived social support increased. Perceived social support as a determinant of state and trait anxiety should be the focus of social work practices in this period.


Assuntos
Ansiedade/psicologia , Infecções por Coronavirus/psicologia , Pneumonia Viral/psicologia , Apoio Social , Adulto , Idoso , Betacoronavirus , Controle de Doenças Transmissíveis , Infecções por Coronavirus/epidemiologia , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Pandemias , Pneumonia Viral/epidemiologia , Escalas de Graduação Psiquiátrica , Turquia/epidemiologia , Incerteza
8.
Adv Clin Exp Med ; 29(9): 1057-1063, 2020 09.
Artigo em Inglês | MEDLINE | ID: mdl-32926601

RESUMO

BACKGROUND: Diabetes mellitus (DM) has become more and more common and has a high morbidity and mortality rate worldwide. It is a multifactorial chronic disease affected by both genetic and environmental factors. OBJECTIVES: To evaluate the association between antioxidant enzyme activities and their genetic variations and the level of malondialdehyde (MDA) in type II diabetes patients living in the Adiyaman province in the southeast part of Turkey. MATERIAL AND METHODS: One hundred patients diagnosed with type II DM (T2DM) and 100 healthy controls were included in the study. Malondialdehyde levels and antioxidant enzyme activities were measured spectrophometrically. DNA isolation was performed and genotyping was carried out using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). RESULTS: Our results revealed no significant differences in genotype distributions and allele frequencies of all polymorphisms between groups (p > 0.05). Significantly elevated MDA levels and a significant reduction in catalase (CAT) and paraoxonase (PON) enzyme activities were observed in patients compared to the control group in terms of study groups and genetic variations (p < 0.05). Moreover, CAT activity was reduced in TT genotype in terms of CAT -262 C/T polymorphism in patients (p < 0.05). Paraoxonase activity was observed to be lower in MM genotype in both groups (p < 0.05). CONCLUSIONS: CAT -262 C/T polymorphism may be one of the factors that lead to severe clinical situation in DM. Our results suggest that TT genotype may be more prone to lipid peroxidation.


Assuntos
Diabetes Mellitus Tipo 2 , Polimorfismo Genético , Estudos de Casos e Controles , Diabetes Mellitus Tipo 2/genética , Frequência do Gene , Genótipo , Humanos , Turquia
9.
Environ Monit Assess ; 192(9): 608, 2020 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-32865639

RESUMO

Population growth, which is the main source of the biggest problems of the world today, combined with migration from rural areas to urban centers, causes the urban centers to be even more concentrated. This necessitates the opening of new residential areas in many city centers, but new residential areas are mostly determined by the decisions of local authorities, who may not base their decisions on scientific data. With the wrong area selection, ordinary natural events can be potentially catastrophic. Such events can result in large numbers of casualties and material damage every year. In this study, an example of applying a method for location selection using various parameters has been realized. The study focuses on Bafra, Turkey (the study area). Risk maps were created in terms of floods and overflows; maps of regions and high-voltage power transmission lines that enjoy a protected area status; and maps of regions in terms of biocomfort suitability. As a result of the evaluation made according to these criteria, it is calculated that only 1.96% of the total working area is suitable for use as a residential area. In relevant literature studies, it was observed that the studies related to the selection of residential areas were carried out only depending on a single standard or criterion. Some suggested biocomfort, and others used vulnerability to risks such as landslide, flood, and earthquakes as their main principle. Studies based on multi-criteria were generally used for purposes such as solid waste site selection and determination of the road routes. The study aims to shed light on the multi-criteria method in an attempt to standardize it in regional planning studies and to inspire similar studies in which different criteria can be used to achieve the maximum efficiency.


Assuntos
Monitoramento Ambiental , Crescimento Demográfico , Resíduos Sólidos , Cidades , Inundações , Turquia
10.
Infez Med ; 28(3): 351-356, 2020 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-32920570

RESUMO

The rapidly increased number of patients with COVID-19 resulted in the shortage of hospital beds. An outpatient follow-up plan was developed for COVID-19 patients with stable clinical condition and no concomitant diseases. The records of COVID-19 first admission clinic were retrospectively reviewed to identify the COVID-19 patients who were followed on home isolation as outpatients between March 17, 2020 and April 18, 2020 in Ankara, Turkey. Demographic and clinical characteristics of the patients, compliance with isolation rules, re-admission rates, and outcomes were investigated. A total of 41 patients with COVID-19 were followed on home isolation without hospitalization. The median age of the patients was 36 years. Twenty-four (58.5%) of 41 patients were female. Twenty-nine (70.7%) patients were healthcare workers. The most common symptoms at admission were cough, myalgia/arthralgia, and loss of smell and/or taste. Fourteen (34.1%) patients were asymptomatic on the first admission. Anti-viral treatment was given to 27 (65.8%) of 41 patients. Four of 41 patients were readmitted to the outpatient clinic and hospitalized. Three patients had worsening respiratory symptoms and pneumonia was detected in CT scans. One patient was hospitalized because of disseminated herpes zoster infection. Two patients who jeopardized the isolation rules were isolated and monitored at another hospital by provincial health directorate teams. If adequate conditions are provided, follow-up on home isolation seems to be a feasible method in carefully selected patients. However, these patients should be monitored closely by an experienced team during the isolation period.


Assuntos
Assistência Ambulatorial/métodos , Antivirais/uso terapêutico , Betacoronavirus , Infecções por Coronavirus/tratamento farmacológico , Isolamento de Pacientes/métodos , Pneumonia Viral/tratamento farmacológico , Adulto , Ocupação de Leitos , Técnicas de Laboratório Clínico/métodos , Infecções por Coronavirus/diagnóstico , Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/transmissão , Feminino , Pessoal de Saúde/estatística & dados numéricos , Humanos , Masculino , Doenças Profissionais/diagnóstico , Doenças Profissionais/tratamento farmacológico , Doenças Profissionais/epidemiologia , Pacientes Ambulatoriais , Pandemias , Pneumonia Viral/diagnóstico , Pneumonia Viral/epidemiologia , Pneumonia Viral/transmissão , Estudos Retrospectivos , Avaliação de Sintomas , Turquia/epidemiologia
11.
Bratisl Lek Listy ; 121(7): 475-480, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32989999

RESUMO

Covid-19 pandemic is spreading rapidly in Turkey. We aimed to examine the numbers and demographic data of patients who applied to the general surgery outpatient clinics and operated in this process. Our primary outcome is to reveal the response of general surgery patients to the Covid-19 pandemic.The first Covid-19 case in Turkey has appeared in March 11, 2020. Patients who were operated on due to a surgical emergency or trauma were evaluated separately. Patients in 3 periods were compared with each other. A total of 12728 patients were examined in general surgery outpatient clinics in 26 working days. It is seen that patients come to the outpatient clinic after the first time the Covid-19 patient is seen. All patients reduced hospitalization after the first death due to Covid-19. Women had reduced going to the hospital earlier than men. There was no change in the number of emergency surgeries. Rapid decrease was observed in the number of elective surgeries.It is not easy to control the entrance and exit of these busy hospitals. The remote diagnosis (mail, phone or video-call) and treatment methods that can be expected in the near future may be even closer with the Corona virus (Tab. 3, Fig. 4, Ref. 15). Keywords: general surgery, Covid-19, outpatient clinics, operation, reaction of patients.


Assuntos
Betacoronavirus , Infecções por Coronavirus , Hospitalização , Pandemias , Pneumonia Viral , Instituições de Assistência Ambulatorial , Feminino , Humanos , Masculino , Turquia
12.
Med Lav ; 111(4): 296-305, 2020 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-32869766

RESUMO

BACKGROUND: Occupational pesticide poisoning is an important public health concern worldwide, especially in developing countries. OBJECTIVES: This study was aimed at determining the prevalence and risk factors of acute pesticide poisoning (APP) among the vegetable and fruit farmers in Karacabey District in northwest Turkey. METHODS: The study group consisted of 565 farmers. The dependent variable of the study is APP defined according to the World Health Organization's APP case definition matrix. The study's independent variables are the farmers' sociodemographic characteristics and the preventive measures they use when they are applying pesticides. The chi-square and logistic regression analysis analyzed the relationship between the dependent and independent variables. RESULTS: A total of 64 (11.3%) farmers reported APP and 75% of them presented to a health institution due to symptoms. The factors associated with increased risk of APP were: illiteracy (odds ratio (OR)=2.5), 14 years and less farming experience (OR=3.3), not reading the pesticide labels (OR=6.4), and contact with liquid pesticides (OR=2.3). -Conclusions: The study shows that approximately one out of ten farmers experience APP. Training programs should be planned and monitored to improve farmers' awareness of the dangers of pesticides, and they should be encouraged to adopt and implement protective measures.


Assuntos
Agricultura , Exposição Ocupacional , Praguicidas , Estudos Transversais , Fazendeiros , Frutas , Conhecimentos, Atitudes e Prática em Saúde , Humanos , Praguicidas/envenenamento , Autorrelato , Turquia , Verduras
13.
Environ Monit Assess ; 192(10): 631, 2020 Sep 09.
Artigo em Inglês | MEDLINE | ID: mdl-32902699

RESUMO

In recent years, it has been difficult to establish a supply-demand balance between urban growth, increasing population, and existing water resources in many countries. In this study, the Bodrum Peninsula, which is an important tourism center for Turkey, was examined in terms of the relationship between the urban growth of the peninsula, population projections, the need for drinking and potable water, and the availability of the existing water resources. Using the Geographic Information System, it has been determined that the urban growth of the peninsula increased by 11.36% between 1985 and 2010. Urban growth is mostly concentrated in the coastal areas where 2 houses are densely built. The population is expected to increase approximately six times between 2010 and 2060. The amount of drinking and potable water required according to the population projection is 12.38, 26.50, 69.12, and 109.50 hm3/year for 2010, 2030, 2050, and 2060 respectively. The existing water resources of the peninsula will be able to meet the requirements until 2030. In order to meet the water needs of the peninsula until 2055, the Bozalan and Gökçeler dams located nearby as well as the Namnam dam located at mid-range to the peninsular should be built. It is not possible to meet the water needs of the peninsula in 2060 with just the near and medium distance water resources. However, by supplying water from the Akköprü dam located at a further distance, it is possible that 2060 water needs can be met.


Assuntos
Crescimento Demográfico , Recursos Hídricos , Conservação dos Recursos Naturais , Monitoramento Ambiental , Turquia , População Urbana , Abastecimento de Água
14.
Acta Dermatovenerol Alp Pannonica Adriat ; 29(3): 115-122, 2020 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-32975297

RESUMO

INTRODUCTION: This questionnaire study evaluates dermatological complaints that may arise due to hygiene measures and anxiety among healthcare professionals (HCPs) during the COVID-19 outbreak. METHODS: A total of 526 volunteers, consisting of doctors and nurses, participated. Demographic features, personal hygiene behavior, personal protective equipment (PPE) use, Hospital Anxiety and Depression Scale-Anxiety (HADS-A) parameters, and symptoms of various dermatological diseases (xerosis, eczema, acne, hair loss, palmar hyperhidrosis, xeromycteria, urticaria, aphthous stomatitis, and seborrheic dermatitis) were investigated. RESULTS: Although the frequency and severity of many dermatological complaints increased during the pandemic period, the most frequent increase was observed in the frequency of complaints suggesting xerosis and eczema. We found that complaints suggesting xerosis and eczema were seen on the hands 2.44 and 3.57 times, respectively, as a result of washing hands 10 times/day, and that handwashing times of 10 seconds or more significantly increased the risk of eczema (5.44 times). Another remarkable result was a fivefold increase in acne complaints among those using any mask. The severity of all complaints except hair loss and seborrheic dermatitis correlated significantly with HADS-A. CONCLUSIONS: Our study showed that the frequency and severity of some dermatological complaints increased in HCPs.


Assuntos
Infecções por Coronavirus/epidemiologia , Eczema/epidemiologia , Dermatoses da Mão/epidemiologia , Pessoal de Saúde/estatística & dados numéricos , Corpo Clínico Hospitalar/estatística & dados numéricos , Pneumonia Viral/epidemiologia , Adulto , Betacoronavirus , Feminino , Luvas Protetoras/estatística & dados numéricos , Humanos , Higiene , Masculino , Exposição Ocupacional/efeitos adversos , Pandemias , Inquéritos e Questionários , Turquia
15.
Lung ; 198(5): 777-784, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32918573

RESUMO

PURPOSE: SARS-CoV-2 (COVID-19) has infected more than 7 million people worldwide in the short time since it emerged in Wuhan, China in December 2019. The aim of this study was to investigate the relationship between serum interleukin 6 (IL-6) and surfactant protein D (SP-D) levels and the clinical course and prognosis of COVID-19. MATERIALS AND METHODS: The study included a total of 108 individuals: 88 patients who were diagnosed with COVID-19 by real-time PCR of nasopharyngeal swab samples and admitted to the Atatürk University Pulmonary Diseases and the Erzurum City Hospital Infectious Diseases department between March 24 and April 15, and 20 asymptomatic healthcare workers who had negative real-time PCR results during routine COVID-19 screening in our hospital. RESULTS: Patients who developed macrophage activation syndrome had significantly higher IL-6 and SP-D levels at the time of admission and on day 5 of treatment compared to the other patients (IL-6: p = 0.001 for both; SP-D: p = 0.02, p = 0.04). Patients who developed acute respiratory distress syndrome had significantly higher IL-6 and SP-D levels at both time points compared to those who did not (p = 0.001 for all). Both parameters at the time of admission were also significantly higher among nonsurvivors compared to survivors (IL-6: p = 0.001, SP-D: p = 0.03). CONCLUSION: In addition to IL-6, which has an important role in predicting course and planning treatment in COVID-19, SP-D may be a novel pneumoprotein that can be used in the clinical course, follow-up, and possibly in future treatments.


Assuntos
Betacoronavirus/isolamento & purificação , Infecções por Coronavirus , Interleucina-6/sangue , Pandemias , Pneumonia Viral , Proteína D Associada a Surfactante Pulmonar/sangue , Técnicas de Laboratório Clínico/métodos , Infecções por Coronavirus/sangue , Infecções por Coronavirus/diagnóstico , Infecções por Coronavirus/epidemiologia , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Masculino , Pessoa de Meia-Idade , Pneumonia Viral/sangue , Pneumonia Viral/diagnóstico , Pneumonia Viral/epidemiologia , Valor Preditivo dos Testes , Prognóstico , Fatores de Risco , Turquia/epidemiologia
16.
PLoS One ; 15(9): e0238614, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32936826

RESUMO

Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and associated with severe respiratory illness emerged in Wuhan, China, in late 2019. The virus has been able to spread promptly across all continents in the world. The current pandemic has posed a great threat to public health concern and safety. Currently, there are no specific treatments or licensed vaccines available for COVID-19. We isolated SARS-CoV-2 from the nasopharyngeal sample of a patient in Turkey with confirmed COVID-19. We determined that the Vero E6 and MA-104 cell lines are suitable for supporting SARS-CoV-2 that supports viral replication, development of cytopathic effect (CPE) and subsequent cell death. Phylogenetic analyses of the whole genome sequences showed that the hCoV-19/Turkey/ERAGEM-001/2020 strain clustered with the strains primarily from Australia, Canada, England, Iran and Kuwait and that the cases in the nearby clusters were reported to have travel history to Iran and to share the common unique nucleotide substitutions.


Assuntos
Betacoronavirus/isolamento & purificação , Pandemias , Cultura de Vírus/métodos , Animais , Austrália , Betacoronavirus/genética , Betacoronavirus/fisiologia , Canadá , Linhagem Celular , Chlorocebus aethiops , Busca de Comunicante , Infecções por Coronavirus , Efeito Citopatogênico Viral , DNA Complementar/genética , DNA Viral/genética , Inglaterra , Genoma Viral , Células HeLa , Humanos , Irã (Geográfico) , Kuweit , Macaca mulatta , Nasofaringe/virologia , Filogenia , Pneumonia Viral , Análise de Sequência de DNA , Viagem , Turquia/epidemiologia , Células Vero , Replicação Viral
17.
Environ Monit Assess ; 192(10): 646, 2020 Sep 17.
Artigo em Inglês | MEDLINE | ID: mdl-32939661

RESUMO

We investigated the associations between the daily variations of coarse particulate matter (PM10) and/or sulfur dioxide (SO2) and hospital admissions for asthma and/or chronic obstructive pulmonary disease (COPD) diseases in Kirsehir, Center of Anatolia of Turkey. We analyzed the poison generalized linear model (GLM) to analyze the association between ambient air pollutants such as PM10 and SO2 and asthma and/or COPD admissions. We investigated single-lag days and multi-lag days for the risk increase in asthma, COPD, asthma, and/or COPD hospital admissions PM10, SO2, and PM10 with SO2 per 10 µg/m3. In single-lag day model a 10 µg/m3 increase in the current day (lag 0) concentrations of PM10 and SO2 corresponded to increase of 1.027 (95% CI:1.022-1.033) and 1.069 (95% CI:1.062, 1.077) for asthma. A 10 µg/m3 increase in the current day (lag 0) concentrations of PM10 and SO2 corresponded to increase of 1.029 (95% CI:1.022-1.035) and 1.065 (95% CI:1.056, 1.075) for COPD. A 10 µg/m3 increase in the current day (lag 0) concentrations of PM10 and SO2 corresponded to increase of 1.028 (95% CI:1.024-1.032) and 1.068 (95% CI:1.062, 1.074) for asthma and/or COPD. It was found that some lag structures were related with PM10 and SO2. Significant lags were detected in some lag structures from the previous first day until the previous eighth day (lag 1 to lag 7) in the asthma, COPD, and asthma and/or COPD hospital admissions in the model created with PM10 with SO2 both in the single-lag day model and in the multi-lag day model. Our study that used GLM in time series analysis showed that PM10 and/or SO2 short-term exposure in single-lag day and multi-lag day models was related with increased asthma, COPD, and asthma and/or COPD hospital admissions in the city between 2016 and 2019 until the previous-eighth day.


Assuntos
Poluentes Atmosféricos/análise , Poluição do Ar/análise , Asma , Doença Pulmonar Obstrutiva Crônica , Monitoramento Ambiental , Humanos , Dióxido de Nitrogênio/análise , Material Particulado/análise , Dióxido de Enxofre/análise , Turquia
18.
Pediatr Infect Dis J ; 39(10): e297-e302, 2020 10.
Artigo em Inglês | MEDLINE | ID: mdl-32932329

RESUMO

BACKGROUND: Coronavirus disease 2019 (COVID-19) primarily affects adults and spares children, whereas very little is known about neonates. We tried to define the clinical characteristics, risk factors, laboratory, and imagining results of neonates with community-acquired COVID-19. METHODS: This prospective multicentered cohort study included 24 neonatal intensive care units around Turkey, wherein outpatient neonates with COVID-19 were registered in an online national database. Full-term and premature neonates diagnosed with COVID-19 were included in the study, whether hospitalized or followed up as ambulatory patients. Neonates without severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) via reverse transcriptase-polymerase chain reaction testing or whose mothers had been diagnosed with COVID-19 during pregnancy were excluded. RESULTS: Thirty-seven symptomatic neonates were included. The most frequent findings were fever, hypoxemia, and cough (49%, 41%, 27%, respectively). Oxygen administration (41%) and noninvasive ventilation (16%) were frequently required; however, mechanical ventilation (3%) was rarely needed. Median hospitalization was 11 days (1-35 days). One patient with Down syndrome and congenital cardiovascular disorders died in the study period. C-reactive protein (CRP) and prothrombin time (PT) levels were found to be higher in patients who needed supplemental oxygen (0.9 [0.1-8.6] vs. 5.8 [0.3-69.2] p = 0.002, 11.9 [10.1-17.2] vs. 15.2 [11.7-18.0] p = 0.01, respectively) or who were severe/critical (1.0 [0.01-8.6] vs. 4.5 [0.1-69.2] p = 0.01, 11.7 [10.1-13.9] vs. 15.0 [11.7-18.0] p = 0.001, respectively). CONCLUSIONS: Symptomatic neonates with COVID-19 had high rates of respiratory support requirements. High CRP levels or a greater PT should alert the physician to more severe disease.


Assuntos
Infecções por Coronavirus/epidemiologia , Infecções por Coronavirus/patologia , Pneumonia Viral/epidemiologia , Pneumonia Viral/patologia , Betacoronavirus , Proteína C-Reativa/metabolismo , Infecções Comunitárias Adquiridas , Infecções por Coronavirus/fisiopatologia , Infecções por Coronavirus/terapia , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Recém-Nascido , Masculino , Oxigênio/administração & dosagem , Pandemias , Pneumonia Viral/fisiopatologia , Pneumonia Viral/terapia , Estudos Prospectivos , Tempo de Protrombina , Fatores de Risco , Turquia/epidemiologia
19.
Environ Monit Assess ; 192(10): 652, 2020 Sep 22.
Artigo em Inglês | MEDLINE | ID: mdl-32964332

RESUMO

Location selection for offshore wind farms is a major challenge for renewable energy policy, marine spatial planning, and environmental conservation. This selection constitutes a multi-criteria decision-making problem, through which parameters like wind velocity, water depth, shorelines, fishing areas, shipping routes, environmental protection areas, transportation, and military zones should be jointly investigated. The aim of the present study was thus to develop an integrated methodology for assessing the siting of bottom-fixed offshore wind farms in two different countries (with different legal, political, and socio/economic characteristics). Our methodology combined multi-criteria decision-making methods and geographical information systems and was implemented in Cyclades (Greece) and in the sea area of Izmir region (Turkey). Experts used fuzzy sets and linguistic terms to achieve more consistent and independent rankings and results. In the Turkish region, the results showed that 519 km2 (10.23%) of the study area is suitable for offshore wind farms, while in the Greek region, only 289 km2 (3.22%) of the study area was found to be suitable. This spatial suitability analysis may contribute to provide some useful recommendations for the spatial marine planning at the regional scale, as well as for the preliminary assessment of new offshore wind farms in both countries.


Assuntos
Fontes Geradoras de Energia , Sistemas de Informação Geográfica , Monitoramento Ambiental , Grécia , Centrais Elétricas , Turquia , Vento
20.
Environ Monit Assess ; 192(10): 655, 2020 Sep 23.
Artigo em Inglês | MEDLINE | ID: mdl-32968858

RESUMO

It is known that some persistent organic pollutants (POPs) are used worldwide, and these pollutants are dangerous for human health. However, there are still countries where measurements of these pollutants have not been adequately measured. Although many studies have been published for determining the concentrations of POPs in Turkey, there are limited studies in Latin American countries like Peru. For this reason, it is essential both to conduct a study in Peru and to compare the study with another country. This study is aimed at determining the atmospheric POPs such as polycyclic aromatic hydrocarbon (PAH), organochlorine pesticide (OCP), and polychlorinated biphenyl (PCB) concentrations using passive air samplers in Yurimaguas (Peru) and Bursa (Turkey). Molecular diagnosis ratios and ring distribution methods were used to determine the sources of PAHs. According to these methods, coal and biomass combustions were among the primary sources of PAHs in Peru, while petrogenic and petroleum were the primary sources of PAHs in Turkey. Then, α-HCH/γ-HCH and ß-/(α+γ)-HCH ratios were used to determine the sources of OCPs. According to the α-HCH/γ-HCH ratios, the primary sources of OCPs in both countries were lindane. Similarly, according to ß-/(α+γ)-HCH ratios, the HCHs have been historically used in Peru while they were recently utilized in Turkey. Finally, homologous group distributions were used to determine the sources of PCBs. Similar distributions of homologous groups were observed in the sampling sites in both countries. Also, the homologous group distributions obtained have been determined that industrial activities could be effective in the sampling areas in both countries. When the cancer risks that could occur via inhalation were evaluated, no significant cancer risk has been determined in both countries.


Assuntos
Poluentes Atmosféricos/análise , Poluentes Ambientais/análise , Hidrocarbonetos Clorados/análise , Praguicidas/análise , Bifenilos Policlorados/análise , Hidrocarbonetos Policíclicos Aromáticos/análise , Monitoramento Ambiental , Humanos , Peru , Medição de Risco , Turquia
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