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Turk Kardiyol Dern Ars ; 48(3): 255-262, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-32281952

RESUMO

OBJECTIVE: This study was an investigation of the role of left ventricular (LV) apical rotation seen in the early period after myocardial infarction (MI) in predicting infarct localization. METHODS: A total of 124 patients with a ST-Segment elevation myocardial infarction (STEMI) diagnosis who underwent primary percutaneous coronary intervention (PCI) and 50 healthy volunteers with similar demographic characteristics were included in the study. The relationship between 2-dimenstional speckle tracking echocardiography (STE)-guided LV apical rotation angle measurements and technetium-99m sestamibi-single-photon emission computed tomography (SPECT)-guided infarct localization was evaluated. Conventional echocardiography and STE were performed on average 2 days after PCI, and gated SPECT myocardial perfusion imaging (MPI) was performed within an average of 60 days. RESULTS: The apical rotation angle was lower in patients with an anterior MI compared with those who had an inferior MI and the control group (AntMI-InfMI: 6.51±2.4°, AntMI-Control: 13.20±2.5°, InfMI-Control: 14.3±2.1°; p value: 0.00, 0.00, 0.15, respectively). SPECT MPI analysis revealed the presence of an LV apical scar in all patients with acute anterior MI, but only 14 of those with inferior MI group (usually the inferoapical wall). The apical rotation angle recorded in patients with apical scar was lower than that of the patients without apical scar (7.6±2.8° and 14.5±2°, respectively; p=0.00). Receiver operating characteristic curve analysis yielded an area under the curve for apical rotation of 0.799 (p<0.01). The optimal cutoff value of 12.1° had a sensitivity of 78.3% and a specificity of 68.2% for predicting LV apical scar following STEMI. CONCLUSION: Detection of apical rotation angle decrease in the early period after STEMI may be useful in predicting extension of infarct scarring to the LV apex.


Assuntos
Ventrículos do Coração/diagnóstico por imagem , Infarto do Miocárdio/complicações , Infarto do Miocárdio/fisiopatologia , Infarto do Miocárdio com Supradesnível do Segmento ST/complicações , Infarto do Miocárdio com Supradesnível do Segmento ST/fisiopatologia , Doença Aguda , Adulto , Infarto Miocárdico de Parede Anterior , Estudos de Casos e Controles , Ecocardiografia/métodos , Feminino , Ventrículos do Coração/patologia , Ventrículos do Coração/fisiopatologia , Humanos , Infarto/patologia , Infarto Miocárdico de Parede Inferior , Masculino , Pessoa de Meia-Idade , Infarto do Miocárdio/patologia , Imagem de Perfusão do Miocárdio/métodos , Salpicos Nucleares/metabolismo , Intervenção Coronária Percutânea/métodos , Valor Preditivo dos Testes , Curva ROC , Estudos Retrospectivos , Rotação , Infarto do Miocárdio com Supradesnível do Segmento ST/diagnóstico , Infarto do Miocárdio com Supradesnível do Segmento ST/cirurgia , Sensibilidade e Especificidade , Tecnécio Tc 99m Sestamibi/administração & dosagem , Tecnécio Tc 99m Sestamibi/metabolismo , Tomografia Computadorizada de Emissão de Fóton Único/métodos
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