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1.
Rev. patol. trop ; 52(1)2023.
Artigo em Inglês | LILACS, BVSDIP | ID: biblio-1537795

RESUMO

Adaptation of the vector and displacement of infected dogs to previously disease-free areas challenges visceral leishmaniasis (VL) control, and leads to geographic dispersion and occurrence in urban and peri-urban areas. Continuous VL control measures over time must be applied with a wide geographic reach, along with better diagnosis practices and timely treatment. The high case-fatality of human VL in areas of recent introduction and its growing association with HIV impose the need for an early diagnosis, treatment and the adoption of active search for human and canine cases incorporated into the routine of periodic home visits by health professionals. The increasing on public rejection of canine euthanasia as a control measure, the limitations of canine therapy with the current available drugs, and the controversies regarding available vaccines for canine protection are discussed. Good prospects on the insecticide-impregnated collars as an effective control measure are emphasized.


Assuntos
Humanos , Cães , Doenças do Cão , Inseticidas/uso terapêutico , Leishmaniose Visceral/prevenção & controle
2.
Rev. patol. trop ; 52(1): 11-24, 2023. mapas, tab
Artigo em Inglês | LILACS, BVSDIP | ID: biblio-1552142

RESUMO

The world is facing a serious viral infection caused by the new Severe Acute Respiratory Syndrome Coronavirus 2. We aimed to evaluate and map the high-risk clusters of COVID-19 in the State of Alagoas, a touristic area in northeastern Brazil, after two years of pandemic by a population-based ecological study, using COVID-19 cases reported in the State of Alagoas, between March, 2020 and April, 2022. We performed a descriptive and statistical analysis of epidemiological data. We then map high-risk areas for COVID-19, using spatial analysis, considering the incidence rate by municipality. 297,972 positive cases were registered; 56.9% were female and 42.7% aged between 20 and 39 years old. Men (OR = 1.59) and older than 60 years old (OR = 29.64) had a higher risk of death, while the highest incidence rates of the disease occurred in the metropolitan region. Our data demonstrate the impact of COVID-19 in the State of Alagoas, through the two years of pandemic. Although the number of cases were greater among women and young adults, the chance of death was greater among men and older adults. High-risk clusters of the disease initially occur in metropolitan cities and tourist areas.


Assuntos
Humanos , COVID-19
3.
Rev. patol. trop ; 52(1): 25-36, 2023. tab; mapas
Artigo em Inglês | LILACS, BVSDIP | ID: biblio-1552207

RESUMO

Leprosy is a chronic infectious disease caused by an acid-resistant bacillus called Mycobacterium leprae and the disease is characterized by its slow multiplication, with an excessively long incubation period. The objective of the research was to evaluate the spatial distribution of leprosy cases among the municipalities of the State of Goiás in 2020. This is a descriptive study and the data collection took place from the Notifiable Diseases Information System (SINAN) in November, 2021 and it considered the diagnosis´ year and the patient's municipality of residence. The following indicators were adopted in the analysis: a) annual prevalence rate per 10,000 inhabitants; b) annual rate of new cases detection in the general population; and c) annual rate of new cases detection in individuals under 15 years of age, these last two per 100,000 inhabitants. The analysis of the spatial occurrence pattern of leprosy in Goiás State municipalities was carried out in the free software Terraview version 4.2.2. A higher prevalence of distribution of the gross rate of the disease was observed in the Central-North and Central-West macro-regions, with a concentration of cases also in the Northeast region of the State. From the 246 Goiás municipalities, 68.7% (n = 169) had cases of leprosy, 18.3% (n = 45) were in a situation of hyperendemia and 23.2% (n = 57) had a very high detection coefficient. Considering the rate of detection in those people under 15 years of age, only 11 municipalities (4.5%) were in a situation of hyperendemia and 1.2% (n = 3) had a very high detection coefficient (5.00 to 9.99/ 10.000 inhabitants). The current investigation indicates the maintenance of leprosy hyperendemic areas in the State of Goiás, when compared to previous studies. This finding highlights the importance of readjustment of leprosy management and assistance in municipalities at greater risk of leprosy hyperendemicity in order to interrupt the M. leprae transmission chain.


Assuntos
Humanos , Características de Residência/estatística & dados numéricos
4.
Rev. patol. trop ; 52(1): 37-49, 2023. tab
Artigo em Inglês | LILACS | ID: biblio-1552256

RESUMO

The extract of Spondias mombin has constituents which may improve psychiatric disorders, in addition to having antiviral, antifungal, and antimicrobial activity. But despite having several benefits, it is necessary to assess whether the extract may interfere with cell metabolism so furthermore its microbicide potential can be explored. Fifteen Wistar rats were used, divided into four groups (control group; control with extract; hyperlipidemic diet; hyperlipidemic diet and extract). For 12 weeks, the animals were weighed and their blood glucose was assessed. Afterwards, they were euthanized, and the biological material was collected. The evaluation confirmed the efficacy of the extract of S. mombin against cell metabolism of rats, without negatively altering cell viability; the group of rats with an hyperlipidemic diet showed an increase in body weight; however, in the individual assessment of the organs, there were no significant changes. The glycemic index, liver parameters, lipids, and mineral ions did not show changes. Furthermore, the antimicrobial potential of S. mombin extract was observed against Staphylococcus aureus ATCC 29213 and Staphylococcus aureus BLACC. The results suggest that S. mombin extract did not interfere with cell viability, did not show cytotoxicity to cells that were exposed to it, nor did it interfere with the metabolism, organs, and biochemical indices of rats with a standard or hyperlipidemic diet. Considering such characteristics and the potential activities observed in this present study, additional evaluation should be conducted to further assess the role of S. mombin extract as a source of new alternative antimicrobial drug as well as its possible beneficial activity to the cardiovascular system.


Assuntos
Animais , Ratos , Hipolipemiantes , Obesidade
5.
Rev. patol. trop ; 52(1): 51-65, 2023. graf.; tab.; mapa
Artigo em Inglês | LILACS, BVSDIP | ID: biblio-1552637

RESUMO

Visceral Leishmaniasis (VL) is a parasitic disease caused by Leishmania protozoa and transmitted by the bite of sand fly insects. This study aimed to describe the epidemiological aspects of VL in Rio Grande do Norte (RN), using variables inserted in the Information System for Notifiable Diseases, for the period from 2013 to 2019. The chi-square test of independence was used with p<0.05 considered statistically significant. 635 cases of VL were reported in RN, with stability of new cases in the analyzed period. 60% of cases were autochthonous, 84 (50.2%) municipalities in RN had autochthonous cases, with 70 (18.2%) cases in Natal and 58 (15.1%) in Mossoró. The most affected age group was 20-59 year old (57.3%) followed by 0-9 year old (23.8%), 10-19 year old (10.4%) and 60 year old or older (8.5%). There was a positive association between the 0-9 and 10-19 ranges with females and 20-59 with males (p=0.0001). Among the 532 individuals, 54.5% had a low level of education, and these, as well as the illiterate, associated with males (p=0.001). 85.3% of 612 cases were in black/brown group and 77.1% of 632 in urban/periurban residents. 27.6% of 500 were co-infected with HIV, 77.5% in males and 89.8% in adults. 70.7% progressed to cure and 6.8% died from VL. The study shows that the control measures adopted within the scope of the National Program for the Control of Leishmaniasis should be reassessed since there has been no decrease in cases, even though it has had stability over the years in Natal and a tendency to growth in Mossoró, the most affected areas.


Assuntos
Humanos , Masculino , Feminino , Sistemas de Informação em Saúde , Leishmaniose Visceral/epidemiologia
6.
Rev. patol. trop ; 52(1): 66-76, 2023. tab
Artigo em Inglês | LILACS | ID: biblio-1552643

RESUMO

The population's living conditions, basic sanitation, hygiene, and poor socioeconomic status, are determining factors for diseases´ transmission, such as intestinal parasitic infections which constitute one of the main public health problems in Brazil. These diseases are considered endemic in several areas of the country, presenting a wide geographic distribution, varying according to environmental conditions and parasites´ species. Therefore, the present study aimed to evaluate the prevalence of intestinal parasites in individuals attending a clinical analysis laboratory in a municipality located in Southern of Brazil. A retrospective study was carried out through the analysis of 2,247 reports of parasitological stool examination from individuals who attended a clinical analysis laboratory located in Veranópolis, Rio Grande do Sul, from September 1st, 2018, to December 31st, 2020. Parasitic structures were found in stool samples from 181 (8.1%) individuals. The protozoans Endolimax nana and Entamoeba coli were the most prevalent parasites, being present in 58.0% and 29.8% of individuals, respectively. A higher prevalence of intestinal parasites was observed in women (52.5%), aged 21 to 60 years old (62.4%). Biparasitism or polyparasitism was present in 7.2% (13/181) of individuals and only 31.7% (713/2247) of samples collected three fecal samples for examination. The low prevalence of intestinal parasites found in the present study may be an indicator of improvements in sanitary, environmental, and health education conditions.


Assuntos
Humanos , Helmintos , Enteropatias Parasitárias
7.
Rev. patol. trop ; 52(1): 77-86, 2023. tab
Artigo em Inglês | LILACS | ID: biblio-1552667

RESUMO

Pediatric patients have particularities in the clinical manifestations and complications of snakebite envenomation (SBEs), and few studies have examined this population. The objective of this paper was to study snakebites in a pediatric age group treated at a reference hospital and to evaluate factors associated with unfavorable evolution. A cross-sectional study with a clinical-epidemiological description and identification of the factors related to unfavorable evolution in patients aged <19 years old seen from January, 2018 to November, 2019 was performed. Complications related to the SBE, such as compartment syndrome, secondary infection, extensive necrosis, hemorrhage, and kidney damage, were considered unfavorable evolution. From the 325 patients in the sample, 58 were aged <19 years old; 40 (69%), 0-12 years old; and 18 (31%), 13-18 years old. All patients had local manifestations (mild, moderate, and severe), and 36 (62%) had an unfavorable evolution. Fourteen (24.1%) patients had compartment syndrome, with a significant risk association between 0 and 12 years old (p = 0.019). Two factors significantly contributed to unfavorable evolution: the timing from the bite to medical care being ≥6 hours and additional antivenom therapy needed. We conclude that the younger the patient, the smaller body segment affected, leading to disproportionality between the affected area and the amount of inoculated venom, contribute to more frequent local manifestations and complications in children rather than adults. Because of the relationship between body area and vascular volume in children differs from that in adults, the same volume of venom inoculated by snakes will be disproportionate in these two groups. Therefore, in the treatment of pediatric patients, increasing the volume of antivenom therapy is possibly necessary. Furthermore, as in adults, six hours between the bite to medical care increases the risk of complications and mortality.


Assuntos
Humanos , Criança , Venenos de Serpentes
8.
Rev. patol. trop ; 51(2): 157-164, 2022. tab
Artigo em Inglês | LILACS | ID: biblio-1417619

RESUMO

This study aims to determine the prevalence of Fasciola hepatica in cattle from the Abancay, Curahuasi, and Tamburco districts in the Abancay province, Apurímac, Peru, during the 2018 rainy season, and the association between prevalence and age, breed, and district of origin. In total, 295 stool samples were collected, namely 34 from Tamburco, 193 from Curahuasi and 68 from Abancay. For coproparasitological evaluation, the four-sieve sedimentation technique described by Girão and Ueno was used. The total prevalence of F. hepatica in the cattle sampled in this study was 50.8% (150/295), and the prevalence by district was 42.6% (29/68) in Abancay, 53.8% (104/193) in Curahuasi, and 50% (17/34) in Tamburco. No significant association was found with the variable district of origin (p<0.05). However, using a bivariate logistic regression analysis, a significant association was found between F. hepatica prevalence and the breed variable (p=0.008). A similar significant association with the breed variable (p=0.007) was also found using a multiple logistic regression analysis. The high prevalence of F. hepatica identified in this study is consistent with previous reports made in the Apurímac Region, an area considered hyperendemic for the parasite, thus highlighting the need for effective health programs to control disease distribution, which may have an economic and, because of its zoonotic character, public health impact.


Assuntos
Parasitos , Fasciola hepatica , Gado , Hepatopatias
9.
Rev. patol. trop ; 51(2)2022.
Artigo em Inglês | LILACS | ID: biblio-1417625

RESUMO

Bamboo internodes can serve as a breeding ground for a diverse mosquito fauna, some with relative epidemiological importance. The goal of this study is to determine the mosquitoes´ species found in the bamboo internodes at the northwestern region of Rio Grande do Sul, Brazil. From September 2016 to August, 2017 immature forms of mosquitoes were collected from bamboos (Bambusa sp.), in the quarterly intervals (ten plants per collection) through 0.5 cm in diameter perforations on 40 internodes sides. After 30 days, the perforated internodes were cut out and their contents were taken to the laboratory where the immature forms of mosquitoes developed to adult stage were identified. A total of 367 immature forms of Culicidae were collected, however only 158 (43.1%) have developed to adult stage and were identified at a specific level. Eight species were identified: Onirium personatum (Lutz, 1904), Sabethes aurescens (Lutz, 1905), Sa. intermedius (Lutz, 1904), Sa. purpureus (Theobald, 1907), Shannoniana fluviatilis (Theobald, 1903), Trichoprosopon pallidiventer (Lutz, 1905), Wyeomyia limai (Lane & Cerqueira, 1942) and Wyeomyia serratoria (Dyar & Nuñez Tovar, 1927). Thus, the study showed the importance of this type of breeding in order to maintain the mosquito fauna in the wild areas in the studied region. The finding of the species On. personatum and Sh. fluviatilis was also reported for the first time in the State.


Assuntos
Plantas , Controle de Mosquitos , Bambusa , Dípteros , Culicidae
10.
Rev. patol. trop ; 51(2)2022. ilus
Artigo em Inglês | LILACS | ID: biblio-1417684

RESUMO

Bed bugs are hematophagous ectoparasites usually found in bedsteads mattresses, and sheets. The bed bug infestations have been increasing dramatically, but only a few cases have been reported in Brazil. We presented a case of a 49-year-old woman with diffuse, extremely itchy skin lesions, after she returned from an international travel.


Assuntos
Prurigo , Pele , Percevejos-de-Cama , Leitos , Cimicidae , Exantema , Doença Relacionada a Viagens
11.
Rev. patol. trop ; 51(3): 1-22, 2022. tab
Artigo em Inglês | LILACS | ID: biblio-1417939

RESUMO

Chagas disease causes an important impact on cardiorespiratory system, functional and working capacity of the patient. Performing a functional assessment on these individuals becomes essential, since the impact of physical limitation is an important factor that is related with other life domains, such as risk of cardiovascular events in a brief period and risk of death. The goal of this work was to perform a literature review to present the evaluative and prognostic value of main valid respiratory and functional tests in patients with Chagas disease, as well as their applicability and reproducibility. A literature search was performed from 1981 to 2020 in Scielo, Pubmed/Medline, Science Direct, Scopus and Web of Science databases. Only complete studies published in English, Portuguese or Spanish were analyzed which specifically discussed the respiratory and functional tests used in patients with Chagas disease. In total, 544 articles were retrieved of which 35 were eligible. The main functional tests approached were Cardiopulmonary Exercise Testing, Incremental Exercise Testing and Six-Minute Walk Test. Several studies show themselves as useful markers for predicting quality of life, mortality and functional impairment, in addition to other patients' characteristics. Several tests can be used to assess the respiratory and functional impact to patients' health, as well as its relationship with important domains of their lives


Assuntos
Qualidade de Vida , Testes de Função Respiratória , Cardiomiopatia Chagásica , Doença de Chagas , Teste de Esforço
12.
Rev. patol. trop ; 51(3): 1-16, 2022. tab. ilus
Artigo em Inglês | LILACS | ID: biblio-1417997

RESUMO

The levels and evolution of antimicrobial resistance of Escherichia coli during 01/2009-06/2010 (Period 1), 01/2012-06-2013 (Period 2) and 07/2013-12/2014 (Period 3) were analyzed. Identification, susceptibility levels to 13 antibiotics and the presence of extendedspectrum ß-lactamases (ESBLs) were determined. Overall, 9,918 microorganisms were isolated as a cause of infection. Of these 3,016 (30.4%) were E. coli, with 1,770 (59%), 992 (33%) and 254 (8%), from the Medicine and the Surgery Departments and the Intensive Care Unit (ICU), respectively. There was a significant increase (p=0.0002) of E. coli throughout considered periods. The isolates presented high levels of resistance (>60%) to cephalosporins, ciprofloxacin and cotrimoxazole, being only susceptible to imipenem (0.3% of resistance) and tigecycline. Overall the analysis of evolution of antimicrobial resistance showed that resistance to cephalosporins and amikacin significantly increased, while, the ones of piperacillintazobactam, cotrimoxazole and gentamicin had significantly decreased. Nevertheless, the ICU isolates showed an inverse scenario for cephalosporins. These findings agree with an increase of ESBLs on the Medicine (56% to 66%; p<0.0001) and on the Surgery (54% to 62%; p=0.0197) departments, with a parallel decrease in the ICU (76% to 68%). In summary, high levels of antimicrobial resistance have been reported among E. coli, with worrisome levels of ESBL. A continuous surveillance of antimicrobial resistance levels in the area is needed.


Assuntos
Resistência Microbiana a Medicamentos , Ciprofloxacina , Cefalosporinas , Escherichia coli , Tigeciclina , Infecções , Unidades de Terapia Intensiva , Antibacterianos
13.
Rev. patol. trop ; 51(3): 1-12, 2022. tab
Artigo em Inglês | LILACS | ID: biblio-1418002

RESUMO

The juice consumption with detoxifying properties has increased in the last few years, but inadequately produced food may transport pathogens. This study aimed to investigate the occurrence of parasitological and microbiological contamination in fruit juices and fruit pulp used for detoxifying purposes. Twenty samples were analyzed, 10 of fruit pulp and 10 juices from July to August 2018. Thermotolerant coliform, mold, and yeast were counted. Parasitological analysis was performed by spontaneous sedimentation method and sedimentation by centrifugation techniques. Results showed that 20% and 60% of the fruit pulp and juice samples exhibited thermotolerant coliform counts above 1 log CFU/mL, respectively. The results showed that 60% of the pulp samples presented mold and yeast counts above 3 log CFU/mL. The protozoa found in the samples were Endolimax nana, Entamoeba coli, and E. histolytica/E. dispar cysts. The presence of thermotolerant coliforms in juices is an indicator of the presence of enteropathogens, mainly Escherichia coli. The high mold and yeast populations and the presence of protozoa in the fruit pulp and juices indicate hygienic and sanitary failures in the food processing. It may be concluded that there is a need for supervision and training in Good Manufacturing Practices by health agencies, aiming at the food safe production.


Assuntos
Parasitologia , Leveduras , Entamoeba , Poluição Ambiental , Escherichia coli , Sucos , Coliformes , Manipulação de Alimentos , Frutas , População
14.
Rev. patol. trop ; 51(3): 1-10, 2022. ilus
Artigo em Inglês | LILACS | ID: biblio-1418011

RESUMO

Parasitosis are the most common diseases in the world, they are responsible for relevant negative consequences in the individuals´ health. The consumption of vegetables in Brazil and in the world is common due to their high nutritional value and they are recommended to be included in the population´s diet. Contaminations in vegetables are most often caused by irrigation water which is contaminated by feces, other forms of contamination are through organic manure containing fecal waste and the contact of vegetables with animals where they are grown. This research evaluated the contamination in vegetables with the purpose of warning the community about hygiene and the correct approach of food handling in order to prevent parasitic infections, contributing to people´s health. Samples were collected from supermarkets and farmers´ markets, where we obtained a total of 30 samples that were analyzed using Hoffman, centrifugation and slide reading´s techniques. In all samples, parasites were found. In six samples non-pathogenic amoebas were found, however this finding means that there was contamination from human or animal feces. And, in the other 24 samples, parasitic structures that cause damage to health were found. This work showed a high level of contamination of the vegetables that are consumed daily by the population and the diseases caused by food which are a concern for the public health. Contaminated vegetables are dangerous considering the transport of parasites that may generate human infections, therefore the importance to create public policies in order to avoid parasitic infections.


Assuntos
Doenças Parasitárias , Parasitologia , Verduras , Contaminação de Alimentos , Doenças Negligenciadas , Alimentos , Manipulação de Alimentos , Supermercados
15.
Rev. patol. trop ; 51(1): 1-16, 2022.
Artigo em Inglês | LILACS | ID: biblio-1410979

RESUMO

Spider envenomation, generically known as arachnidism, is described in many places around the world. In terms of medical importance, the following genera of animals stand out as the main origin of the morbid condition: Atrax (Sidney funnel web spider), Steatoda (false black widow), Latrodectus (black widow), Loxosceles (brown spider) and Phoneutria (armed spider), the last three causing accidents involving spiders in Brazil. This article, part 1 of 2, aims to present the main aspects of arachnidism in the country, with an emphasis on the biology and geographical distribution of spiders, biochemistry of the venom, pathogenesis and epidemiology of arachnidism, as well as prevention of the morbid condition.


Assuntos
Picada de Aranha , Venenos de Aranha , Aranhas , Peçonhas
16.
Rev. patol. trop ; 51(1): 17-30, 2022.
Artigo em Inglês | LILACS | ID: biblio-1410981

RESUMO

Arachnidism, spider envenomation, is an important public health issue in different parts of the world. Its clinical evolution depends on the genus involved. Symptoms and signs range from skin alterations to systemic manifestations. The success of treatment, consisting of serotherapy and other measures, depends on the patient's immediate care. In addition to the potential injury to human hosts, spider venom has been investigated for the therapy of various diseases. Based on these considerations, this article, part 2 of 2, aims to present the main aspects of spider accidents, focusing on clinical findings, diagnosis, differential diagnosis and treatment, as well as highlighting the potential of the venom of these arachnids.


Assuntos
Picada de Aranha , Venenos de Aranha , Aranhas , Peçonhas , Ferimentos e Lesões
17.
Rev. patol. trop ; 51(1): 31-50, 2022. ilus, tab
Artigo em Inglês | LILACS | ID: biblio-1411448

RESUMO

Tungiasis is a neglected parasitic disease caused by penetration of female Tunga penetrans under the skin, causing important health outcomes in humans. Therefore, the aim of this study was to describe the prevalence of tungiasis in Brazil and in its federative units. In November 2019, an investigation was carried out to find studies published from 1980 onwards in MEDLINE, LILACS, Cochrane, CINAHL, Scopus, Web of Science and Embase databases, and in the gray literature, using descriptors related to the prevalence of tungiasis caused by T. penetrans in Brazil. Of the 542 studies found, only 16 published between 2002 and 2010 met the eligibility criteria to be included in this systematic review. Of the 16 selected publications, 14 addressed the prevalence of tungiasis in communities in the Northeast region of the country, one in the South and one in the Southeast. The general prevalence of the parasitosis in the studies ranged from 1.6% to 54.8%, predominantly in the five to nine age group. Eight studies considered the prevalence by gender, ranging from 2.2% to 62.2% for females and 1.1% to 62.5% for males. This systematic review presents an unprecedented survey of the prevalence of tungiasis, a parasitic disease whose dissemination is facilitated by several factors, occuring mainly in low-income communities. Considering the regionalization of the findings, the scarcity of publications, as well as disease neglect, more studies are required.


Assuntos
Humanos , Doenças Parasitárias , Pele , Tunga , Tungíase
18.
Rev. patol. trop ; 51(1): 51-61, 2022. tab
Artigo em Inglês | LILACS | ID: biblio-1411450

RESUMO

The metropolitan region of Belém-PA suffers human fecal pollution in the local water supply system favoring the increase in cases of water circulating diseases in the population, especially the most socioeconomically vulnerable. Therefore, it is necessary to compile information on cases of these diseases over the years in this region, in order to better define public health policies. Thus, this work aims to contribute to the gathering of this information through a literature review selecting articles found in the SciELO, Pubmed and Google Academic databases with publications between 2005 and 2021 in Portuguese and English. The neighborhoods most affected by water circulation diseases proved were Guamá, Marco, Jurunas, Tapanã, Telegrafo and Terra Firme, located close to hydrographic basins, rivers and canals and are subject to flooding due to high tides and overflowing canals. In addition, the population in these neighborhoods is considered underprivileged. The most cited diseases and symptoms were leptospirosis, worms and diarrhea, which are easily prevented. Total and thermotolerant coliforms were also widely described, being the main indicators of fecal water contamination. The importance of sanitary measures is evidenced, as these reduce cases of water supply diseases in urban centers and improve population health. The quality of the water in the supply network is also important to mitigate the prevalence of these diseases.


Assuntos
Humanos , Poluição da Água , Abastecimento de Água , Saneamento , Coliformes , Saúde da População , Política de Saúde , Leptospirose
19.
Rev. patol. trop ; 51(1): 63-72, 2022.
Artigo em Inglês | LILACS | ID: biblio-1411459

RESUMO

Dengue is a worldwide spread arboviral disease. Huánuco region is an endemic area for dengue. Understanding the influence of Knowledge, Attitudes and Practices (KAP) in dengue endemic areas can provide important insight for improving public health policies. The purpose of this study was to understand the KAP about dengue in the marginal urban city of Tingo Maria, district of Rupa-Rupa, a rain forest area in Huánuco region and its association with positive serology for dengue. An analytical, retrospective, cross-sectional study was carried out in which a randomized sample of 112 people were evaluated using a semi structured questionnaire and tested for IgG against dengue virus. Most participants recruited were from marginal urban settlements. The median age was 38 years and 64% were female. A bivariate analysis showed an association between educational level and serological positivity. Over 95% of participants with only primary school education had a positive serological test for dengue. No statistical significances were found between attitudes towards dengue control initiatives (p=0.221), preventive practices against dengue (p=0.773), and the level of knowledge about dengue (p=0.073). Although attitudes, preventive practices and level of knowledge were not related to positive serology in dengue cases, educational level showed an association with serological positivity for dengue.


Assuntos
Imunoglobulina G , Testes Sorológicos , Dengue , Vírus da Dengue
20.
Rev. patol. trop ; 51(1): 73-85, 2022. tab
Artigo em Inglês | LILACS | ID: biblio-1412856

RESUMO

December 2019 saw several cases of pneumonia of unknown origin reported in Wuhan, China; the cause of this unknown disease was later identified as the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The purpose of the present study was to evaluate the epidemiological profile of coronavirus disease 2019 (COVID-19) in the North Region of Brazil to assess possible correlations between demographic, social and health factors as well as adherence to safety protocols and the epidemiological profile of COVID-19. Information was obtained via a socio epidemiological survey carried out using Google Forms shared on various social media platforms from May 13 to 20, 2020. 6,781 people, living in the State of Pará, participated in the study of which only 682 (10.1%) had been diagnosed with COVID-19. Of these, 43 (6.3%) required hospitalization. 155 (23.5%) tested positive by RT-PCR associated with computed tomography. The RT-PCR test, with no association with other methods, was performed in 77 (11.6%) cases and serology performed in 360 cases (54.6%). There was a higher prevalence of confirmed cases (457, 67.0%) in females than in males, and the predominant age group was 30 to 40 years of age (214 participants, 31.4%). Considering the relatively homogeneous demographic profile of the sample, continued research is vital, preferably multi-centric studies, to obtain relevant data regarding the epidemiological dynamics of COVID-19; this data will allow the development of pandemic-prevention strategies that consider the social, cultural and political aspects of specific locations


Assuntos
Pneumonia , Pandemias , SARS-CoV-2 , COVID-19/epidemiologia , Hospitalização
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