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1.
NPJ Biofilms Microbiomes ; 10(1): 69, 2024 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-39143108

RESUMO

The gut microbiota (GM) can regulate bone mass, but its association with incident fractures is unknown. We used Cox regression models to determine whether the GM composition is associated with incident fractures in the large FINRISK 2002 cohort (n = 7043, 1092 incident fracture cases, median follow-up time 18 years) with information on GM composition and functionality from shotgun metagenome sequencing. Higher alpha diversity was associated with decreased fracture risk (hazard ratio [HR] 0.92 per standard deviation increase in Shannon index, 95% confidence interval 0.87-0.96). For beta diversity, the first principal component was associated with fracture risk (Aitchison distance, HR 0.90, 0.85-0.96). In predefined phyla analyses, we observed that the relative abundance of Proteobacteria was associated with increased fracture risk (HR 1.14, 1.07-1.20), while the relative abundance of Tenericutes was associated with decreased fracture risk (HR 0.90, 0.85-0.96). Explorative sub-analyses within the Proteobacteria phylum showed that higher relative abundance of Gammaproteobacteria was associated with increased fracture risk. Functionality analyses showed that pathways related to amino acid metabolism and lipopolysaccharide biosynthesis associated with fracture risk. The relative abundance of Proteobacteria correlated with pathways for amino acid metabolism, while the relative abundance of Tenericutes correlated with pathways for butyrate synthesis. In conclusion, the overall GM composition was associated with incident fractures. The relative abundance of Proteobacteria, especially Gammaproteobacteria, was associated with increased fracture risk, while the relative abundance of Tenericutes was associated with decreased fracture risk. Functionality analyses demonstrated that pathways known to regulate bone health may underlie these associations.


Assuntos
Fraturas Ósseas , Microbioma Gastrointestinal , Humanos , Masculino , Feminino , Fraturas Ósseas/microbiologia , Fraturas Ósseas/epidemiologia , Fraturas Ósseas/etiologia , Pessoa de Meia-Idade , Finlândia/epidemiologia , Idoso , Bactérias/classificação , Bactérias/genética , Bactérias/isolamento & purificação , Metagenoma , Estudos de Coortes , Incidência , Metagenômica/métodos , Proteobactérias/genética , Proteobactérias/isolamento & purificação , Fatores de Risco , Adulto
2.
JBJS Case Connect ; 14(3)2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-39172876

RESUMO

CASE: We present a 17-year-old male patient with an initially missed posterior sternoclavicular fracture dislocation who presented with symptoms related to thrombotic emboli arising from a pseudoaneurysm. He was treated 6 weeks after injury with a figure-of-eight tendon allograft repair with good clinical outcomes. CONCLUSION: This is a unique presentation that highlights the significant risk of a missed diagnosis, life-threatening complications that may ensue, and biomechanically superior surgical intervention.


Assuntos
Falso Aneurisma , Humanos , Masculino , Adolescente , Falso Aneurisma/diagnóstico por imagem , Falso Aneurisma/cirurgia , Falso Aneurisma/etiologia , Articulação Esternoclavicular/lesões , Articulação Esternoclavicular/diagnóstico por imagem , Articulação Esternoclavicular/cirurgia , Clavícula/lesões , Clavícula/cirurgia , Clavícula/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Fraturas Ósseas/complicações , Fraturas Ósseas/diagnóstico por imagem , Luxações Articulares/cirurgia , Luxações Articulares/diagnóstico por imagem , Luxações Articulares/complicações , Fratura-Luxação/diagnóstico por imagem , Fratura-Luxação/cirurgia , Fratura-Luxação/complicações
3.
BMC Nephrol ; 25(1): 265, 2024 Aug 19.
Artigo em Inglês | MEDLINE | ID: mdl-39160464

RESUMO

BACKGROUND: Complications of prolonged continuous kidney replacement therapy (CKRT) have not been well described. Our objective was to describe mineral metabolism and bone findings in children who required prolonged CKRT. METHODS: In this single center prospective observational study, we enrolled 37 patients who required CKRT for ≥ 28 days with regional citrate anticoagulation. Exposure was duration on CKRT and outcomes were 25-hydroxy vitamin D and osteopenia and/or fractures. RESULTS: The prevalence of vitamin D deficiency and insufficiency was 17.2% and 69.0%, respectively. 29.7% of patients had radiographic findings of osteopenia and/or fractures. There was no association between vitamin D deficiency or insufficiency with age or ethnicity. Time on CKRT and intact PTH levels were not predictive of vitamin D levels. Children with chronic liver disease were more likely to have osteopenia and/or fractures compared children with other primary diagnoses, odds ratio (3.99 (95%CI, 1.58-2.91), p = 0.003) after adjusting for age and time on CKRT. CONCLUSION: Vitamin D deficiency and/or insufficiency, and osteopenia and/or fractures are prevalent among children who require CKRT for a prolonged period. The risk for MBD may be higher with chronic liver disease. Higher doses of vitamin D may be required to maintain normal levels while on CKRT.


Assuntos
Doenças Ósseas Metabólicas , Terapia de Substituição Renal Contínua , Deficiência de Vitamina D , Vitamina D , Humanos , Feminino , Masculino , Doenças Ósseas Metabólicas/epidemiologia , Doenças Ósseas Metabólicas/etiologia , Estudos Prospectivos , Deficiência de Vitamina D/epidemiologia , Deficiência de Vitamina D/complicações , Deficiência de Vitamina D/sangue , Deficiência de Vitamina D/tratamento farmacológico , Criança , Vitamina D/sangue , Vitamina D/análogos & derivados , Vitamina D/uso terapêutico , Pré-Escolar , Adolescente , Fraturas Ósseas/epidemiologia , Fraturas Ósseas/etiologia , Prevalência
4.
J Bone Joint Surg Am ; 106(16): 1507-1511, 2024 Aug 21.
Artigo em Inglês | MEDLINE | ID: mdl-39167064

RESUMO

ABSTRACT: Musculoskeletal changes occur with gender-affirming hormonal therapy (GAHT) and gender-affirming surgery (GAS) used in the care of transgender adolescents and adults. Survey results have shown that orthopaedic surgeons desire to care for transgender individuals but express concern over a knowledge deficit. This article reviews the physiology and pathophysiology that may occur with GAHT and GAS. Transgender women have lower bone mineral density (BMD) prior to GAHT than cisgender men. Limited fracture data would suggest that transgender women >50 years of age have fracture rates similar to those of cisgender women. Transgender men have normal BMD prior to GAHT and are not at an increased risk for fracture compared with cisgender women. The use of puberty-blocking medications in the care of transgender youth does result in a decline in BMD, which returns to baseline with GAHT, but the effect of delaying puberty on maximal BMD and the lifetime fracture risk are unknown. At present, dual x-ray absorptiometry (DXA) is used to measure BMD and assess fracture risk. Attention should be paid to using the appropriate reference group in the interpretation of DXA for transgender individuals. Promote musculoskeletal health by ensuring appropriate calcium, vitamin D, weight-bearing activity, and a healthy lifestyle. Adherence to GAHT needs to be encouraged to avoid bone loss. Data with regard to therapy for osteoporosis in transgender patients have been lacking, but, at present, use of available therapies is expected to be effective. Information with regard to differences in other musculoskeletal health issues such as joint injuries has been lacking in transgender individuals.


Assuntos
Densidade Óssea , Pessoas Transgênero , Humanos , Masculino , Feminino , Procedimentos de Readequação Sexual/efeitos adversos , Cirurgia de Readequação Sexual , Fraturas Ósseas/etiologia , Fatores Sexuais
5.
BMC Musculoskelet Disord ; 25(1): 645, 2024 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-39148072

RESUMO

BACKGROUND: A coracoid process fracture combined with an acromioclavicular (AC) joint dislocation is an uncommon injury that typically causes significant pain and limits shoulder movement. Open reduction and internal fixation have been the traditional treatment approach. However, arthroscopic techniques are emerging as a promising alternative for managing these injuries. CASE REPRESENTATION: A 35-year-old woman presented with right shoulder pain following an accidental fall. Imaging studies revealed a coracoid process fracture along with an AC joint dislocation. The fracture was classified as an Eyres Type IIIA, which warranted surgical intervention. Our team performed arthroscopic coracoid fracture reduction and internal fixation surgery, as well as AC joint dislocation repair using Kirschner wires. Six months after surgery, the patient demonstrated a satisfactory functional outcome with complete bone healing. CONCLUSION: This case report highlights the potential of arthroscopic reduction and fixation as a novel treatment option for fractures of the coracoid base.


Assuntos
Artroscopia , Parafusos Ósseos , Processo Coracoide , Fixação Interna de Fraturas , Fraturas Ósseas , Humanos , Feminino , Adulto , Fixação Interna de Fraturas/métodos , Fixação Interna de Fraturas/instrumentação , Artroscopia/métodos , Processo Coracoide/cirurgia , Processo Coracoide/lesões , Processo Coracoide/diagnóstico por imagem , Fraturas Ósseas/cirurgia , Fraturas Ósseas/diagnóstico por imagem , Resultado do Tratamento , Articulação Acromioclavicular/cirurgia , Articulação Acromioclavicular/lesões , Articulação Acromioclavicular/diagnóstico por imagem , Escápula/cirurgia , Escápula/lesões , Escápula/diagnóstico por imagem
6.
Sci Rep ; 14(1): 18913, 2024 08 14.
Artigo em Inglês | MEDLINE | ID: mdl-39143227

RESUMO

Life expectancy in sub-Saharan Africa (SSA) has increased owing to economic growth and improvements in medical care. An increased representation of older people among orthopaedic trauma victims is a significant consequence of population ageing, as shown in previous studies, including few in SSA. This retrospective review in Nigeria aims to corroborate previous studies and highlight the emergence of geriatric orthopaedic trauma (GOT) as a public health concern in SSA. Among 241 orthopaedic trauma in-patients aged ≥ 60, the mortality rate was 3.7%. They made up 21.2% of adult orthopaedic trauma admissions. The incidence of GOT increased steadily over the five-year study period with a spike during COVID-19 lockdown. Males constituted 51%. Mean age was 72.5 years (range, 60-105 years). Mean distance to the hospital was 35.8 km and 50.6% lived farther than 10 km. The main causes of injury were falls (50.6%) and traffic crashes (48.1%). Fractures were the predominant (91.7%) injuries. Univariate analyses revealed significant differences along age and gender stratifications. Longer distance to the hospital significantly delayed presentation. The study supports previous studies and shows that GOT is evolving as a public health concern in SSA. The 2030 Sustainable Development agenda is apt to stem the trend.


Assuntos
COVID-19 , Centros de Atenção Terciária , Humanos , Nigéria/epidemiologia , Idoso , Masculino , Feminino , Idoso de 80 Anos ou mais , Centros de Atenção Terciária/estatística & dados numéricos , Pessoa de Meia-Idade , COVID-19/epidemiologia , Estudos Retrospectivos , Fraturas Ósseas/epidemiologia , Acidentes de Trânsito/estatística & dados numéricos , Acidentes por Quedas/estatística & dados numéricos , Incidência , Ferimentos e Lesões/epidemiologia , SARS-CoV-2/isolamento & purificação , Hospitalização/estatística & dados numéricos
7.
J Orthop Trauma ; 38(9): 459-465, 2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39150296

RESUMO

OBJECTIVES: To identify the infection rate in patients with combined pelvic ring and bladder injuries. Secondary aims included identifying treatment and injury factors associated with infection. DESIGN: Retrospective review. SETTING: Single Level I Tertiary Academic Center. PATIENTS SELECTION CRITERIA: All patients over a 12-year period with combined pelvic ring and bladder injuries were evaluated. Exclusion criteria were nonoperative management of the pelvic ring, isolated posterior fixation, and follow-up <90 days. OUTCOME MEASURE AND COMPARISONS: Primary outcome measured was deep infection of the anterior pelvis requiring surgical irrigation and debridement. RESULTS: In total, 106 patients with anterior stabilization of the pelvis in the setting of a bladder injury were included. Seven patients (6.6%) developed a deep infection and required surgical debridement within 90 days. Patients undergoing open reduction and internal fixation with plating of the anterior pelvis and acute concomitant bladder repair had an infection rate of 2.2% (1/43). Patients undergoing closed reduction and anterior fixation with either external fixation or percutaneous rami screw after bladder repair had an infection rate of 17.6% (3/17). There was a higher infection rate among patients with combined intraperitoneal (IP) and extraperitoneal (EP) bladder injuries (23%) when compared with those with isolated EP (3.8%) or IP (9.1%) bladder injuries (P = 0.029). CONCLUSIONS: Acute open reduction and internal fixation of the anterior pelvis in patients with combined pelvic ring and bladder injuries has a low infection rate. Patients with combined IP and EP bladder injuries are at increased risk of infection compared with those with isolated IP and EP injuries. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Fraturas Ósseas , Ossos Pélvicos , Bexiga Urinária , Humanos , Masculino , Ossos Pélvicos/lesões , Estudos Retrospectivos , Feminino , Bexiga Urinária/lesões , Bexiga Urinária/cirurgia , Adulto , Pessoa de Meia-Idade , Fraturas Ósseas/cirurgia , Fraturas Ósseas/complicações , Fixação Interna de Fraturas/efeitos adversos , Fatores de Risco , Adulto Jovem , Infecção da Ferida Cirúrgica/epidemiologia , Infecção da Ferida Cirúrgica/etiologia , Desbridamento , Idoso , Traumatismo Múltiplo/cirurgia , Resultado do Tratamento
8.
J Orthop Trauma ; 38(9): 477-483, 2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39150298

RESUMO

OBJECTIVES: To identify factors that contribute to iatrogenic sciatic nerve palsy during acetabular surgery through a Kocher-Langenbeck approach and to evaluate if variation among individual surgeons exists. DESIGN: Retrospective cohort. SETTING: Level I trauma center. PATIENT SELECTION CRITERIA: Adults undergoing fixation of acetabular fractures (AO/OTA 62) through a posterior approach by 9 orthopaedic traumatologists between November 2010 and November 2022. OUTCOME MEASURES AND COMPARISONS: The prevalence of iatrogenic sciatic nerve palsy and comparison of the prevalence and risk of palsy between prone and lateral positions before and after adjusting for individual surgeon and the presence of transverse fracture patterns in logistic regression. Comparison of the prevalence of palsy between high-volume (>1 patient/month) and low-volume surgeons. RESULTS: A total of 644 acetabular fractures repaired through a posterior approach were included (median age 39 years, 72% male). Twenty of 644 surgeries (3.1%) resulted in iatrogenic sciatic nerve palsy with no significant difference between the prone (3.1%, 95% confidence interval [CI], 1.9%-4.9%) and lateral (3.3%, 95% CI, 1.3%-8.1%) positions (P = 0.64). Logistic regression adjusting for surgeon and transverse fracture pattern demonstrated no significant effect for positions (odds ratio 1.0, 95% CI, 0.3-3.9). Transverse fracture pattern was associated with increased palsy risk (odds ratio 3.0, 95% CI, 1.1-7.9). Individual surgeon was significantly associated with iatrogenic palsy (P < 0.02). CONCLUSIONS: Surgeon and the presence of a transverse fracture line predicted iatrogenic nerve palsy after a posterior approach to the acetabulum in this single-center cohort. Surgeons should perform the Kocher-Langenbeck approach for acetabular fixation in the position they deem most appropriate, as the position was not associated with the rate of iatrogenic palsy in this series. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Acetábulo , Fraturas Ósseas , Doença Iatrogênica , Neuropatia Ciática , Humanos , Acetábulo/lesões , Acetábulo/cirurgia , Masculino , Feminino , Doença Iatrogênica/epidemiologia , Adulto , Estudos Retrospectivos , Fraturas Ósseas/cirurgia , Neuropatia Ciática/etiologia , Neuropatia Ciática/epidemiologia , Pessoa de Meia-Idade , Posicionamento do Paciente/métodos , Fixação Interna de Fraturas/efeitos adversos , Fixação Interna de Fraturas/métodos , Nervo Isquiático/lesões , Prevalência
9.
J Orthop Trauma ; 38(9): 466-471, 2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39150297

RESUMO

OBJECTIVES: To determine the effect of obesity on systemic complications after operative pelvic ring injuries. DESIGN: Retrospective cohort study. SETTING: Single level 1 trauma center. PATIENT SELECTION CRITERIA: All patients at a level 1 trauma center who underwent operative fixation of a pelvic ring injury from 2015 to 2022 were included. Patients were grouped based on body mass index (BMI) into 4 categories (normal = BMI <25, overweight = BMI 25-30, obese = BMI 30-40, and morbidly obese BMI >40). OUTCOME MEASURES AND COMPARISONS: Systemic complications including acute respiratory distress syndrome, pneumonia, sepsis, deep venous thrombosis (DVT), pulmonary embolism, ileus, acute kidney injury (AKI), myocardial infarction, and mortality were recorded. Patients who developed a complication were compared with those who did not regarding demographic and clinical parameters to determine risk factors for each complication. RESULTS: A total of 1056 patients underwent pelvic ring fixation including 388 normal BMI, 267 overweight, 289 obese, and 112 morbidly obese patients. The average age of all patients was 36.9 years, with a range from 16 to 85 years. Overall, 631 patients (59.8%) were male. The overall complication and mortality rates were 23.2% and 1.4%, respectively. BMI was a significant independent risk factor for all-cause complication with an odds ratio of 1.67 for overweight, 2.30 for obese, and 2.45 for morbidly obese patients. The risk of DVT and AKI was also significantly increased with every weight class above normal with ORs of 5.06 and 3.02, respectively, for morbidly obese patients (BMI >40). CONCLUSIONS: This study demonstrated that among patients undergoing pelvic ring fixation, higher BMI was associated with increased risks of overall complication, specifically DVT and AKI. As the prevalence of obesity continues to increase in the population, surgeons should be cognizant that these patients may be at higher risk of certain postoperative complications during the initial trauma admission. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Fraturas Ósseas , Obesidade , Ossos Pélvicos , Complicações Pós-Operatórias , Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Adulto , Ossos Pélvicos/lesões , Estudos Retrospectivos , Fraturas Ósseas/cirurgia , Fraturas Ósseas/complicações , Idoso , Complicações Pós-Operatórias/epidemiologia , Complicações Pós-Operatórias/etiologia , Obesidade/complicações , Idoso de 80 Anos ou mais , Adulto Jovem , Adolescente , Fatores de Risco , Índice de Massa Corporal , Fixação Interna de Fraturas/efeitos adversos , Estudos de Coortes
10.
J Orthop Trauma ; 38(9): 510-514, 2024 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-39150302

RESUMO

OBJECTIVES: To report on adverse events during magnetic resonance imaging (MRI) in patients with external fixators. METHODS: . DESIGN: Retrospective case series. SETTING: Two Level 1 trauma centers. PATIENT SELECTION CRITERIA: Patients with external fixators on the appendicular skeleton or pelvis undergoing MRI between January 2005 and September 2023. OUTCOME MEASURES AND COMPARISONS: Adverse events, defined as any undesirable event associated with the external fixator being inside or outside the MRI bore during imaging, including (subjective) heating, displacement or pullout of the external fixator, or early MRI termination for any reason. RESULTS: A total of 97 patients with 110 external fixators underwent at least one MRI scan with an external fixator inside or outside of the MRI bore. The median age was 51 years (interquartile range: 39-63) and 56 (58%) were male. The most common external fixator locations were the ankle (24%), knee (21%), femur (21%), and pelvis (19%). The median duration of the MRI was 40 minutes (interquartile range: 26-58), 86% was performed using 1.5-Tesla MRI, and 14% was performed using 3.0-Tesla MRI. Ninety-five percent of MRI was performed for the cervical spine/head. Two MRI scans (1.6%), one of the shoulder and one of the head and cervical spine, with the external fixator outside of the bore were terminated early because of patient discomfort. There were no documented events of displacement or pullout of the external fixator. CONCLUSIONS: These findings suggest that MRI scans of the (cervical) spine and head can be safely obtained in patients with external fixators on the appendicular skeleton or pelvis. Given the low numbers of MRI scans performed with the external fixator inside the bore, additional studies are necessitated to determine the safety of this procedure. The results from this study can aid orthopaedic surgeons, radiologists, and other stakeholders in developing local institutional guidelines on MRI scanning with external fixators in situ. LEVEL OF EVIDENCE: Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Fixadores Externos , Fraturas Ósseas , Imageamento por Ressonância Magnética , Segurança do Paciente , Humanos , Masculino , Pessoa de Meia-Idade , Imageamento por Ressonância Magnética/métodos , Feminino , Estudos Retrospectivos , Adulto , Fraturas Ósseas/cirurgia , Fraturas Ósseas/diagnóstico por imagem , Fixação de Fratura/métodos , Centros de Traumatologia
11.
Zhongguo Gu Shang ; 37(7): 706-12, 2024 Jul 25.
Artigo em Chinês | MEDLINE | ID: mdl-39104073

RESUMO

OBJECTIVE: Evaluation of the clinical efficacy of f trochanteric flip osteotomy combined with Kocher-Langenbeck approach for high acetabular posterior wall fracture. METHODS: Between January 2020 and December 2022, 20 patients with high acetabular posterior wall fractures were retrospectively analyzed, including 12 males and 8 females, aged 18 to 75 years old. They were divided into two groups according to the different surgical methods. Ten patients were treated with greater trochanteric osteotomy combined with Kocher-Langenbeck approach as the observation group, including 5 males and 5 females, aged from 18 to 75 years old. Ten patients were treated with Kocher-Langenbeck approach alone as the control group, including 7 males and 3 females, aged from 18 to 71 years old. Matta reduction criteria were used to evaluate the reduction quality of the two groups, and Harris score was used to compare the hip function of the two groups at the latest follow-up. The operation time, blood loss and postoperative complications of the two groups were analyzed. RESULTS: All patients were followed up for 10 to 24 months. According to the Matta fracture reduction quality evaluation criteria, the observation group achieved anatomical reduction in 6 cases, satisfactory reduction in 3 cases, and unsatisfactory reduction in 1 case, while the control group only achieved anatomical reduction in 3 cases, satisfactory reduction in 3 cases, and unsatisfactory reduction in 4 cases. At the final follow-up, the Harris hip score ranged from 71.4 to 96.6 in the observation group and 65.3 to 94.5 in the control group. According to the results of Harris score. The hip joint function of the observation group was excellent in 6 cases, good in 3 cases, and fair in 1 case. The hip joint function of the control group was excellent in 2 cases, good in 3 cases, fair in 3 cases, and poor in 2 cases. In the observation group, the intraoperative blood loss ranged from 300 to 700 ml, and the operation duration ranged from 120 to 180 min;in the control group, the intraoperative blood loss ranged from 300 to 650 ml, and the operation duration ranged from 100 to 180 min. Complications in the observation group included 1 case of traumatic arthritis and 1 case of heterotopic ossification, while complications in the control group included 3 cases of traumatic arthritis, 3 cases of heterotopic ossification and 1 case of hip abduction weakness. CONCLUSION: Trochanteric flip osteotomy combined with the Kocher-Langenbeck approach significantly improved anatomical fracture reduction rates, enhanced excellent and good hip joint function outcomes, and reduced surgical complication incidence compared to the Kocher-Langenbeck approach alone. Clinical application of this combined approach is promising, although larger studies are needed for further validation.


Assuntos
Acetábulo , Osteotomia , Humanos , Masculino , Feminino , Osteotomia/métodos , Pessoa de Meia-Idade , Adulto , Idoso , Estudos Retrospectivos , Acetábulo/cirurgia , Acetábulo/lesões , Adulto Jovem , Adolescente , Fêmur/cirurgia , Fraturas Ósseas/cirurgia , Fixação Interna de Fraturas/métodos , Resultado do Tratamento
12.
Adv Emerg Nurs J ; 46(3): 228-233, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39094083

RESUMO

Hamate fractures are uncommon, but early and accurate diagnosis is critical to prevent negative outcomes. Hamate fractures may present initially to emergency departments, and diagnosis can be challenging. This case report of a common hamate fracture may aid in increasing emergency advanced practice nurse knowledge to identify these fractures in practice.


Assuntos
Fraturas Ósseas , Hamato , Humanos , Hamato/lesões , Fraturas Ósseas/diagnóstico , Serviço Hospitalar de Emergência , Masculino , Feminino
13.
JBJS Rev ; 12(8)2024 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-39106323

RESUMO

BACKGROUND: Intimate partner violence (IPV) is a prevalent issue in the United States, despite universal screening measures for women of reproductive age. Orthopaedic surgeons have a unique opportunity to intervene in cases of IPV as musculoskeletal injuries, including fractures, are the second most common type of injury seen in IPV patients. This systematic literature review aims to identify patterns in musculoskeletal injuries caused by IPV to increase identification of patients afflicted by IPV. METHODS: A comprehensive search of PubMed, PsycINFO, and Web of Science yielded 316 articles. Included were cohort studies and literature reviews of patients with an IPV-associated orthopaedic injury. Excluded were case studies, perspective articles, material predating 2003, and studies with pediatric or elderly populations. Sixteen articles met criteria. RESULTS: Data supported historical findings that musculoskeletal injury is the second most common injury in patients with IPV, with upper extremity fractures prevailing. Minimally displaced phalanges fractures were most common (9.9%-64%), and isolated ulnar fractures had significant relative risk of IPV association (8.5-12.8). Patients with multiple fractures of varying chronicity were more likely to be victims of IPV (sensitivity 25.2%, specificity 99.2%, positive predictive value 96.2%), and these chronic fractures matched patterns of acute injury caused by IPV. New findings in male victims included a higher proportion of lower extremity and pelvic fractures seen in male cohorts. CONCLUSION: This study synthesizes evidence of IPV-related orthopaedic injuries, offering objective criteria for identifying victims. Despite limitations in fracture descriptions, the findings aid various physicians in recognizing IPV victims. Considering ongoing IPV prevalence and screening challenges, further research on injury patterns is recommended. LEVEL OF EVIDENCE: Level III. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Fraturas Ósseas , Violência por Parceiro Íntimo , Humanos , Violência por Parceiro Íntimo/estatística & dados numéricos , Fraturas Ósseas/epidemiologia , Fraturas Ósseas/etiologia , Feminino , Masculino
14.
An Acad Bras Cienc ; 96(suppl 1): e20230095, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-39109696

RESUMO

This study investigated the effects of ovariectomy and caffeine intake on bone health in rats on calcium-deficient diet. Forty adults female Wistar rats were divided into 4 groups in a 2x2 factorial design: Ovary (OVX/SHAM) and Caffeine (placebo/caffeine). The animals were housed in individual cages for 8 weeks, receiving 18-20g of AIN-93M diet per day, containing 50% of the daily recommended intake of calcium. The rats underwent ovariectomy (OVX) or laparotomy (SHAM) surgery. Caffeine groups received 6mg of caffeine/kg/day. After euthanasia, the tibia and femur were dissected to determine the calcium content and bone fracture strength, respectively. Blood sample was collected to determine serum Ostase. 24-hour urine was analyzed for excreted calcium and NTx. Reduced bone fracture strength and calcium content were observed in OVX and Caffeine groups. When observed separately, OVX group showed increased urinary NTx and lower bone weight, blood ostase, and urinary calcium. Caffeine groups showed elevated urinary calcium. There was a positive correlation between bone fracture strength and calcium content. NTx correlated negatively with bone calcium, fracture strength and thickness. In conclusion, both OVX and caffeine intake debilitate bone health in rats on calcium-deficient diet.


Assuntos
Densidade Óssea , Cafeína , Cálcio , Ovariectomia , Ratos Wistar , Animais , Feminino , Cafeína/administração & dosagem , Cálcio/sangue , Cálcio/urina , Cálcio/análise , Densidade Óssea/efeitos dos fármacos , Ratos , Cálcio da Dieta/administração & dosagem , Cálcio da Dieta/análise , Osteoporose , Fraturas Ósseas
15.
JAMA Netw Open ; 7(8): e2425106, 2024 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-39106069

RESUMO

Importance: The reasons for the increased fracture risk in type 2 diabetes (T2D) are not fully understood. Objective: To determine if poorer skeletal characteristics or worse physical function explain the increased fracture risk in T2D. Design, Setting, and Participants: This prospective observational study is based on the population-based Sahlgrenska University Hospital Prospective Evaluation of Risk of Bone Fractures study cohort of older women, performed in the Gothenburg area between March 2013 and May 2016. Follow-up of incident fracture data was completed in March 2023. Data analysis was performed between June and December 2023. Exposures: Data were collected from questionnaires and through examination of anthropometrics, physical function, and bone measurements using bone densitometry (dual-energy x-ray absorptiometry), and high-resolution peripheral computed tomography. A subsample underwent bone microindentation to assess bone material strength index (BMSi). Main Outcomes and Measures: Baseline assessment of bone characteristics and physical function and radiograph verified incident fractures. Results: Of 3008 women aged 75 to 80 years, 294 women with T2D (mean [SD] age, 77.8 [1.7] years) were compared with 2714 women without diabetes (mean [SD] age, 77.8 [1.6] years). Women with T2D had higher bone mineral density (BMD) at all sites (total hip, 4.4% higher; femoral neck (FN), 4.9% higher; and lumbar spine, 5.2% higher) than women without. At the tibia, women with T2D had 7.4% greater cortical area and 1.3% greater density, as well as 8.7% higher trabecular bone volume fraction. There was no difference in BMSi (T2D mean [SD], 78.0 [8.3] vs controls, 78.1 [7.3]). Women with T2D had lower performance on all physical function tests. The study found 9.7% lower grip strength, 9.9% slower gait speed, and 13.9% slower timed up-and-go time than women without diabetes. During a median (IQR) follow-up of 7.3 (4.4-8.4) years, 1071 incident fractures, 853 major osteoporotic fractures (MOF), and 232 hip fractures occurred. In adjusted (for age, body mass index, clinical risk factors, and FN BMD) Cox regression models, T2D was associated with an increased risk of any fracture (HR, 1.26; 95% CI, 1.04-1.54) and MOF (HR, 1.25; 95% CI, 1.00-1.56). Conclusions and Relevance: In this cohort study of older women, T2D was associated with higher BMD, better bone microarchitecture, and no different BMSi but poorer physical function, suggesting that poor physical function is the main reason for the increased fracture risk in T2D women.


Assuntos
Densidade Óssea , Diabetes Mellitus Tipo 2 , Humanos , Diabetes Mellitus Tipo 2/epidemiologia , Diabetes Mellitus Tipo 2/complicações , Diabetes Mellitus Tipo 2/fisiopatologia , Feminino , Idoso , Estudos Prospectivos , Idoso de 80 Anos ou mais , Fatores de Risco , Fraturas Ósseas/epidemiologia , Fraturas Ósseas/etiologia , Suécia/epidemiologia , Absorciometria de Fóton , Incidência
16.
Rev Med Suisse ; 20(883): 1404-1408, 2024 Aug 21.
Artigo em Francês | MEDLINE | ID: mdl-39175289

RESUMO

In most cases, conventional radiology interpretations are straightforward, enabling a precise diagnosis to be made by combining them with a range of anamnestic and clinical arguments. However, omitting post-traumatic osteoarticular anomalies when interpreting radiographs can have serious functional consequences for the patient. In order to prevent diagnostic errors, it is essential to be aware of certain rules governing the indication of imaging and its systematic interpretation.


Dans la majorité des cas, les interprétations de la radiologie ostéoarticulaire conventionnelle sont simples et permettent de retenir un diagnostic précis en les combinant avec un faisceau d'arguments anamnestiques et cliniques. Cependant, l'omission d'anomalies ostéoarticulaires post-traumatiques lors de l'interprétation peut occasionner des conséquences fonctionnelles graves pour le patient. La connaissance de certaines règles d'indication à l'imagerie ainsi qu'une interprétation systématique permettent de prévenir les erreurs diagnostiques.


Assuntos
Radiografia , Humanos , Radiografia/métodos , Radiografia/estatística & dados numéricos , Fraturas Ósseas/diagnóstico por imagem
17.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi ; 38(8): 942-946, 2024 Aug 15.
Artigo em Chinês | MEDLINE | ID: mdl-39175315

RESUMO

Clavicle fracture is a common orthopedic injury, accounting for approximately 2.6%-4% of all adult skeletal fractures. In 2023, the American Academy of Orthopaedic Surgeons (AAOS) developed evidence-based treatment guidelines for clavicle fractures, which include 4 recommendations and 10 options. This article, based on a thorough review of the guidelines, discusses the clinical treatment of clavicle fractures, aiming to share advancements and the latest diagnostic and therapeutic considerations with orthopedic colleagues to enhance treatment outcomes.


Assuntos
Clavícula , Fraturas Ósseas , Clavícula/lesões , Humanos , Fraturas Ósseas/cirurgia , Fraturas Ósseas/terapia , Fixação Interna de Fraturas/métodos , Guias de Prática Clínica como Assunto , Cirurgiões Ortopédicos , Estados Unidos , Ortopedia/normas
18.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi ; 38(8): 954-960, 2024 Aug 15.
Artigo em Chinês | MEDLINE | ID: mdl-39175317

RESUMO

Objective: To explore the effectiveness of reduction robot combined with navigation robot-assisted minimally invasive treatment for Tile type B pelvic fractures. Methods: Between January 2022 and February 2023, 10 patients with Tile type B pelvic fractures were admitted. There were 6 males and 4 females with an average age of 45.5 years (range, 30-71 years). The fractures were caused by traffic accident in 5 cases, bruising by heavy object in 3 cases, and falling from height in 2 cases. The interval between injury and operation ranged from 4-13 days (mean, 6.8 days). There were 2 cases of Tile type B1 fractures, 1 case of Tile type B2 fracture, and 7 cases of Tile type B3 fractures. After closed reduction under assistance of reduction robot, the anterior ring was fixed with percutaneous screws with or without internal fixator, and the posterior ring was fixed with sacroiliac joint screws under assistance of navigation robot. The time of fracture reduction assisted by the reduction robot was recorded and the quality of fracture reduction was evaluated according to the Matta scoring criteria. The operation time, intraoperative fluoroscopy frequency and time, intraoperative bleeding volume, and incidence of complications were also recorded. During follow-up, the X-ray film of pelvis was taken to review the fracture healing, and the Majeed score was used to evaluate hip joint function. Results: The time of fracture reduction was 42-62 minutes (mean, 52.3 minutes). The quality of fracture reduction according to the Matta scoring criteria was rated as excellent in 4 cases, good in 5 cases, and poor in 1 case, with excellent and good rate of 90%. The operation time was 180-235 minutes (mean, 215.5 minutes). Intraoperative fluoroscopy was performed 18-66 times (mean, 31.8 times). Intraoperative fluoroscopy time was 16-59 seconds (mean, 28.6 seconds). The intraoperative bleeding volume was 50-200 mL (range, 110.0 mL). No significant vascular or nerve injury occurred during operation. All patients were followed up 13-18 months (mean, 16 months). X-ray films showed that all fractures healed with the healing time of 11-14 weeks (mean, 12.3 weeks). One case of ectopic ossification occurred during follow-up. At last follow-up, the Majeed score was 70-92 (mean, 72.7), and the hip joint function was rated as excellent in 2 cases and good in 8 cases, with the excellent and good rate of 100%. Conclusion: The reduction robot combined with navigation robot-assisted minimally invasive treatment for Tile type B pelvic fractures has the characteristics of intelligence, high safety, convenient operation, and minimally invasive treatment, which can achieve reliable effectiveness.


Assuntos
Fixação Interna de Fraturas , Fraturas Ósseas , Procedimentos Cirúrgicos Minimamente Invasivos , Ossos Pélvicos , Procedimentos Cirúrgicos Robóticos , Humanos , Masculino , Pessoa de Meia-Idade , Feminino , Ossos Pélvicos/lesões , Ossos Pélvicos/cirurgia , Adulto , Estudos Retrospectivos , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Fraturas Ósseas/cirurgia , Fixação Interna de Fraturas/métodos , Fixação Interna de Fraturas/instrumentação , Idoso , Procedimentos Cirúrgicos Robóticos/métodos , Resultado do Tratamento , Parafusos Ósseos , Fixadores Externos , Cirurgia Assistida por Computador/métodos
19.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi ; 38(8): 947-953, 2024 Aug 15.
Artigo em Chinês | MEDLINE | ID: mdl-39175316

RESUMO

Objective: To explore effectiveness of minimally invasive internal fixation with locking plates for mid-shaft clavicle fractures. Methods: Between October 2022 and August 2023, 28 patients with mid-shaft clavicle fractures were treated by minimally invasive internal fixation with locking plates. There were 10 males and 18 females with a mean age of 46.2 years (range, 18-74 years). The fractures were caused by traffic accident in 16 patients, sports-related injury in 7 patients, and other injuries in 5 patients. According to Robinson classification, the fractures were classified as type 2A1 in 1 case, type 2A2 in 6 cases, type 2B1 in 15 cases, and type 2B2 in 6 cases. The interval between fracture and operation ranged from 5 hours to 21 days (median, 1.0 days). The pain visual analogue scale (VAS) score was 8.1±1.6. The VAS score at 3 days after operation and the occurrence of complications after operation were recorded. During follow-up, X-ray films were re-examined to observe the healing of the fracture; the shoulder joint function was evaluated according to the Constant-Murley score at 6 months, and the length of the incision scar (total length of the distal and proximal incisions) was measured. Results: All operations were successfully completed without any subclavian vascular or nerve damage. All incisions healed by first intention. The VAS score was 1.2±0.7 at 3 days after operation, and there was a significant difference in VAS score between pre- and post-operation ( t=8.704, P<0.001). At 1 week after operation, the patient's shoulder was basically painless, and they resumed normal life. All patients were followed up 12-20 months (mean, 13.3 months). X-ray films showed that the bone callus began to form at 2-4 months after operation (mean, 2.7 months). There was no delayed healing or non healing of the fracture, and no loosening or fracture of the internal fixators during follow-up. At 6 months after operation, the mean total incision length was 1.5 cm (range, 1.1-1.8 cm); no patient complained of numbness or paresthesia on subclavicular region or anterior chest wall. The Constant-Murley score of shoulder joint function was 93-100 (mean, 97.6). Conclusion: Minimally invasive internal fixation with locking plates is a good surgical method for treating mid-shaft clavicle fractures, with simple operation, minimal trauma, good postoperative results, and high satisfaction.


Assuntos
Placas Ósseas , Clavícula , Fixação Interna de Fraturas , Fraturas Ósseas , Procedimentos Cirúrgicos Minimamente Invasivos , Humanos , Clavícula/lesões , Clavícula/cirurgia , Masculino , Fixação Interna de Fraturas/métodos , Fixação Interna de Fraturas/instrumentação , Feminino , Pessoa de Meia-Idade , Adulto , Procedimentos Cirúrgicos Minimamente Invasivos/métodos , Fraturas Ósseas/cirurgia , Idoso , Adolescente , Adulto Jovem , Resultado do Tratamento , Consolidação da Fratura
20.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi ; 38(8): 981-986, 2024 Aug 15.
Artigo em Chinês | MEDLINE | ID: mdl-39175321

RESUMO

Objective: To compare the effectiveness of open reduction and hook plate fixation versus closed indirect reduction and dorsal extension blocking Kirschner wire fixation for bony mallet fingers. Methods: The clinical data of 68 patients with bony mallet finger who admitted between May 2019 and June 2022 were retrospectively analyzed. Among them, 33 cases were in the open group (treated with open reduction and hook plate fixation) and 35 cases were in the closed group (treated with closed indirect reduction and dorsal extension blocking Kirschner wire fixation). There was no significant difference between the two groups in terms of gender, age, the affected side, the affected finger, cause of injury, time from injury to operation, and Wehbé-Schneider classification ( P>0.05). The operation time, intraoperative fluoroscopy frequency, fracture healing time, time of returning to work, and postoperative complications were recorded and compared between the two groups. At 12 months after operation, visual analogue scale (VAS) score was used to assess the pain of the injured finger, active flexion range of motion and extension deficit of the distal interphalangeal joint (DIP) were measured by goniometer, and the effectiveness was assessed by Crawford criteria. Results: All patients in the two groups were followed up 12-26 months, with an average of 15 months. There was no significant difference in the follow-up time between the closed group and the open group ( P>0.05). The operation time in the closed group was shorter than that in the open group, and the intraoperative fluoroscopy times, the fracture healing time, and the time of returning to work in the closed group were more than those in the open group, and the differences were significant ( P<0.05). In the closed group, there were 5 cases of pinning tract infection and 3 cases of small area pressure ulcer skin necrosis on the dorsal side of the finger, which were cured after intensive nursing and dressing change. Local nail depression deformity occurred in 7 cases in the open group, and the deformity disappeared after removal of plate. The incisions of the other patients healed uneventfully without complications such as infection, skin necrosis, exposure of the internal fixation, or nail deformity. There was no significant difference in the incidence of skin necrosis between the two groups ( P>0.05), but the differences in the incidence of infection and nail deformity between the two groups were significant ( P<0.05). There was no significant difference in VAS score, DIP active flexion range of motion, DIP extension deficiency, or Crawford criteria evaluation between the two groups at 12 months after operation ( P>0.05). At last follow-up, there was no DIP osteoarthritis and joint degeneration in both groups. Conclusion: Open reduction and hook plate fixation versus closed indirect reduction and dorsal extension blocking Kirschner wire fixation have their own advantages and disadvantages, but both of them have good results in the treatment of bony mallet fingers. Open reduction and hook plate fixation is recommended for young patients with bony mallet fingers who are eager to return to work.


Assuntos
Placas Ósseas , Fios Ortopédicos , Traumatismos dos Dedos , Fixação Interna de Fraturas , Consolidação da Fratura , Humanos , Fixação Interna de Fraturas/métodos , Fixação Interna de Fraturas/instrumentação , Masculino , Feminino , Traumatismos dos Dedos/cirurgia , Resultado do Tratamento , Amplitude de Movimento Articular , Fraturas Ósseas/cirurgia , Adulto , Duração da Cirurgia , Redução Aberta/métodos
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