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1.
Food Chem ; 367: 130725, 2022 Jan 15.
Artigo em Inglês | MEDLINE | ID: mdl-34390908

RESUMO

Grains of three specialty maize varieties and one conventional maize variety cultivated in China were collected and dissected to obtain the germ, endosperm, and pericarp fraction, and the distribution pattern of phosphorus, carotenoids, and tocochromanols was determined. The results showed that phytochemical contents varied significantly among different maize fractions. The germ fraction accounted for 78.3 to 86.5% of the total phosphorus present in the maize kernels. Over 86.9% of carotenoids were located in the endosperm. Except for waxy maize, 64.5 to 74.8% of the tocochromanols were contributed by the germ. Considerable differences in phytochemical contents were observed between the genotypes. Waxy maize contained the highest content of tocopherols, tocotrienols and tocochromanols meanwhile waxy maize had the lowest carotenoid and phytate phosphorus content. High lysine maize contained the highest levels in carotenoids and lowest tocochromanols. Over all, total carotenoids were significantly inversely associated with total tocochromanols.


Assuntos
Carotenoides , Zea mays , Carotenoides/análise , China , Fósforo , Tocoferóis , Zea mays/genética
2.
Food Chem ; 368: 130797, 2022 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-34399178

RESUMO

This work monitored the effect of ripening and variety on the physiochemical quality and flavor of fermented Chinese chili pepper (Paojiao). Three commercial varieties of chili pepper (Capsicum frutescens Linn.) at three ripening stages were selected. Physiochemical quality (color, texture, and vitamin C) and flavor properties [capsaicinoids, free amino acid (FAA), and aroma] were determined and compared by multivariate data analysis. The hardness and chewiness decreased, while the contents of vitamin C, capsaicin, and taste-active FAAs increased in Paojiao with ripening. More volatiles were found in green peppers. Fingerprinting and multivariate data analysis revealed that ester, aldehydes, and terpenes were discriminant volatiles that significantly changed in Paojiao during ripening. In general, ripening and variety greatly affect the physiochemical and flavor quality of peppers and their effects intensify after fermentation.


Assuntos
Capsicum , Capsaicina/análise , China , Aromatizantes , Paladar
3.
Food Chem ; 368: 130826, 2022 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-34454369

RESUMO

The safety and quality of aquatic foods are a public concern due to their content of pollutants, such as arsenic. A formula is derived for quantifying the benefit-risk ratio (HQ) of the essential polyunsaturated fatty acids vs. arsenic in Chinses mitten crabs. Among these arsenic species, the proportion of inorganic arsenic, which is extremely harmful to the human body, is<5%, and its level does not exceed the national standard limit. Meanwhile, comparing with the HQ from the original method, the HQs from groups 0 min, 5 min, 15 min are significantly higher(p < 0.05). This suggests the original assessment method could underestimate the risk of eating crabs. Eating steamed crabs is easier to digest essential fatty acids (EFAs) than eating raw crabs, and it also protects consumers against arsenic exposure. To achieve a good balance of dietary benefits and risks, the steaming duration of the crabs should exceed 30 min.


Assuntos
Arsênio , Braquiúros , Animais , China , Digestão , Humanos , Nutrientes , Medição de Risco
4.
BMC Health Serv Res ; 21(1): 1053, 2021 Oct 05.
Artigo em Inglês | MEDLINE | ID: mdl-34610829

RESUMO

BACKGROUND: Many internal migrants during the urbanization process in China are Migrant Parents, the aging group who move to urban areas to support their family involuntarily. They are more vulnerable economically and physically than the younger migrants. However, the fragmentation of rural and urban health insurance schemes divided by "hukou" household registration system limit migrant's access to healthcare services in their resident location. Some counties have started to consolidate the Urban Resident Basic Medical Insurance (URBMI) and the New Rural Cooperative Medical Scheme (NRCMS) as one Integrated Medical Insurance Schemes (IMIS) from 2008. The consolidation aimed to reduce the disparity between different schemes and increase the health care utilization of migrants. RESULTS: Using the inpatient sample of migrant parents from China Migrants Dynamic Survey in 2015, we used Ordinary Least Squares (OLS) for regression models. We found that the migrant parents covered by the IMIS are more likely to choose inpatient services and seek medical treatment in the migrant destination. We further subdivide Non-IMISs into NCMSs and URBMIs in the regression to alleviate the doubt about endogenous. The results revealed that the migrant parents in IMIS use more local medical services than both of them in URBMI and NCMS. CONCLUSIONS: The potential mechanisms of our results could be that IMIS alleviates the difficulty of seeking medical care in migrant destinations by improving the convenience of medical expense reimbursement and enhancing health insurance benefits.


Assuntos
Migrantes , China , Humanos , Seguro Saúde , Pais , Aceitação pelo Paciente de Cuidados de Saúde
5.
BMC Health Serv Res ; 21(1): 1048, 2021 Oct 05.
Artigo em Inglês | MEDLINE | ID: mdl-34610843

RESUMO

BACKGROUND: In China, the primary health care (PHC) system has been designated responsible for control and prevention of COVID-19, but not treatment. Suspected COVID-19 cases presenting to PHC facilities must be transferred to specialist fever clinics. This study aims to understand the impact of COVID-19 on PHC delivery and on antibiotic prescribing at a community level in rural areas of central China. METHODS: Qualitative semi-structured interviews were conducted with 18 PHC practitioners and seven patients recruited from two township health centres and nine village clinics in two rural residential areas of Anhui province. Interviews were transcribed verbatim and analysed thematically. RESULTS: PHC practitioners reported a major shift in their work away from seeing and treating patients (due to government-mandated referral to specialist Covid clinics) to focus on the key public health roles of tracing, screening and educating in rural areas. The additional work, risk, and financial pressure that PHC practitioners faced, placed considerable strain on them, particularly those working in village clinics. Face to face PHC provision was reduced and there was no substitution with consultations by phone or app, which practitioners attributed to the fact that most of their patients were elderly and not willing or able to switch. Practitioners saw COVID-19 as outside of their area of expertise and very different to the non-COVID-19 respiratory tract infections that they frequently treated pre-pandemic. They reported that antibiotic prescribing was reduced overall because far fewer patients were attending rural PHC facilities, but otherwise their antibiotic prescribing practices remained unchanged. CONCLUSIONS: The COVID-19 pandemic had considerable impact on PHC in rural China. Practitioners took on substantial additional workload as part of epidemic control and fewer patients were seen in PHC. The reduction in patients seen and treated in PHC led to a reduction in antibiotic prescribing, although clinical practice remains unchanged. Since COVID-19 epidemic control work has been designated as a long-term task in China, rural PHC clinics now face the challenge of how to balance their principal clinical and increased public health roles and, in the case of the village clinics, remain financially viable.


Assuntos
Antibacterianos , COVID-19 , Idoso , Antibacterianos/uso terapêutico , China , Humanos , Pandemias , Atenção Primária à Saúde , SARS-CoV-2
6.
Comput Intell Neurosci ; 2021: 7348599, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34630551

RESUMO

Based on the theoretical mechanism analysis of FDI, regional innovation, and green economic efficiency, this article uses China's provincial panel data to calculate the provincial green economic efficiency level based on the three-stage DEA method and uses the system GMM model, intermediary effect model, and threshold model to empirically test the specific effects and transmission paths of FDI on the efficiency of the green economy. Research shows that FDI is one of the important factors that promote the improvement of green economic efficiency. Subregional tests have found that FDI has a significant regional heterogeneity in promoting the efficiency of the green economy. The mediation effect test found that the mediation effect of regional innovation is significant, and FDI can significantly promote the growth of green economic efficiency through regional innovation. The threshold effect analysis found that there are significant and effective double thresholds for regional economic levels, and the impact of FDI on green economic efficiency is heterogeneous within different threshold intervals. The research conclusions provide new inspiration for China to allocate FDI more rationally and efficiently under the new development pattern.


Assuntos
Internacionalidade , Investimentos em Saúde , China
7.
Medicine (Baltimore) ; 100(39): e27310, 2021 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-34596129

RESUMO

ABSTRACT: The association between serum total cholesterol (TC) level and incident atherosclerotic cardiovascular disease (ASCVD) in patients with follicular thyroid cancer postthyroidectomy is unknown.This was a retrospective study and patients (n = 384) were divided into low and high TC groups according to the median TC level. Incidence of composite ASCVD (myocardial infarction, ischemic stroke, and cardiovascular death) was compared between these 2 groups and factors contributing to the association of TC and ASCVD were evaluated.Patients in the high TC group were older and more likely to have diabetes and have higher C-reactive protein level. After thyroidectomy, serum levels of free triiodothyronine and free thyroxine were lower while thyroid-stimulating hormone level was higher in the high TC group. 31.6% and 39.7% of patients developed hypothyroidism in the low and high TC groups (P < .05) postthyroidectomy. The incidence rate of composite ASCVD was higher in the high TC versus low TC groups, with incidence rate ratio of 1.69 (95% confidence interval [CI]: 1.07-2.69), which was mainly driven by a higher incidence rate of myocardial infarction in the high TC group (incidence rate ratio: 2.11 and 95% CI: 1.10-4.20). In unadjusted model, higher TC was associated with 73% higher risk of composite ASCVD. After adjustment for hypothyroidism, the association of higher TC and composite ASCVD was attenuated into insignificance, with hazard ratio of 0.92 and 95% CI: 0.81 to 1.34.Increased TC level was associated with composite ASCVD, which might be attributed to hypothyroidism postthyroidectomy. The use of levothyroxine might help to prevent hypercholestemia and reduce the incidence of ASCVD.


Assuntos
Adenocarcinoma Folicular/epidemiologia , Aterosclerose/epidemiologia , Colesterol/sangue , Neoplasias da Glândula Tireoide/epidemiologia , Adenocarcinoma Folicular/cirurgia , Adulto , Fatores Etários , Idoso , Índice de Massa Corporal , Doenças Cardiovasculares/epidemiologia , China/epidemiologia , Comorbidade , Feminino , Humanos , Incidência , Masculino , Pessoa de Meia-Idade , Estudos Retrospectivos , Fatores de Risco , Fatores Sexuais , Hormônios Tireóideos/sangue , Neoplasias da Glândula Tireoide/cirurgia
8.
Medicine (Baltimore) ; 100(39): e27315, 2021 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-34596131

RESUMO

ABSTRACT: Participation in volunteer activity has positive effects on health among elderly. Few studies have investigated the association between volunteer activity and depression among Chinese elderly. This study aimed to examine the association between volunteer activity and depression among the elderly in China regarding rural-urban differences.Totally 8255 subjects from the 2015 China Health and Retirement Longitudinal Study were selected in this study. Depression was assessed by 10-item Center for Epidemiologic Studies Depression Scale. Types and frequency of volunteer activity were measured in the questionnaire. Multiple linear regression analysis was used to explore the relationship between volunteer activity and depression of elderly.In our study, the urban elderly had lower depressive scores than rural elderly (6.7 ±â€Š5.8 vs. 9.1 ±â€Š6.7). After adjustment for all covariates, our results revealed that almost daily participation in formal volunteer activities was negatively associated with depression among urban elderly (B = -2.69, SE = 1.05, P = .010); almost daily caring for a sick or disabled adult was positively associated with depression among both urban and rural elderly (urban:B = 3.13, SE = 1.54, P = .043; rural:B = 2.56, SE = 1.18, P = .031).These findings suggested that there was a negative association between formal volunteer activity and depression among urban elderly, while there was a positive association between caring for a sick or disabled adult and depression among both urban and rural elderly. The government should take effective measures to encourage the elderly to participate in formal volunteer activities to prevent them from depression.


Assuntos
Depressão/epidemiologia , População Rural/estatística & dados numéricos , População Urbana/estatística & dados numéricos , Voluntários/psicologia , Fatores Etários , Idoso , Idoso de 80 Anos ou mais , Envelhecimento/psicologia , Cuidadores/psicologia , China/epidemiologia , Feminino , Comportamentos Relacionados com a Saúde , Humanos , Estilo de Vida , Estudos Longitudinais , Masculino , Pessoa de Meia-Idade , Fatores Sexuais , Fatores Socioeconômicos
9.
Medicine (Baltimore) ; 100(39): e27323, 2021 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-34596133

RESUMO

BACKGROUND: Mild cognitive impairment (MCI), as a common neurodegenerative aging disease representing an intermediate stage between normal cognitive functioning and dementia, poses an excessive burden on health care. The clinical benefit of Chinese herbal medicines (CHMs) for MCI remains inconclusive. This study is aimed at evaluating the efficacy and acceptability of CHMs through meta-analysis and trial sequential analysis (TSA). METHODS: We applied extensive strategies on preliminary literature screening to identify relevant randomized controlled trials which meticulously compare any of CHMs interventions with placebo groups as monotherapy for MCI. The primary outcome of this study is the change of global cognitive function, and the secondary outcomes include assessments of activities of daily living, mood, and adverse events. Data synthesis, risk of bias assessment, sensitivity and subgroup analyses, and TSA will be conducted with application of Review Manager, Stata, and TSA software. The quality of the evidence will be evaluated using the Grading of Recommendations Assessment, Development and Evaluation instrument. INPLASY registration number: INPLASY202190006 (https://inplasy.com/inplasy-2021-9-0006/). RESULTS: This study will confirm the clinical efficacy and safety of CHMs when used in the treatment of patients with MCI. CONCLUSION: This study will provide reliable evidence and references for the selection of CHMs in therapy and future clinical research of MCI.


Assuntos
Disfunção Cognitiva/tratamento farmacológico , Medicamentos de Ervas Chinesas/uso terapêutico , Atividades Cotidianas , Afeto/efeitos dos fármacos , China , Medicamentos de Ervas Chinesas/administração & dosagem , Medicamentos de Ervas Chinesas/efeitos adversos , Humanos , Ensaios Clínicos Controlados Aleatórios como Assunto , Projetos de Pesquisa
10.
Medicine (Baltimore) ; 100(39): e27361, 2021 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-34596147

RESUMO

ABSTRACT: The aim of this study is to investigate the association between baseline neutrophil-to-lymphocyte ratio (NLR) and progression-free survival (PFS), overall survival (OS) and radiological response in castration-resistant prostate cancer patients treated with docetaxel.Forty-one prostate cancer patients who were treated with docetaxel were selected. Univariable and multivariable Cox regression models were used to predict the association of baseline NLR as a dichotomous variable with PFS and OS after chemotherapy initiation.In Kaplan-Meier analysis, the median PFS (9.8 vs 7.5 months, P = .039, Fig. 1) and OS (17.6 vs 14.2 months, P = .021, Fig. 2) was higher in patients who did not have an elevated NLR than in those with an elevated NLR. In univariate analysis, the pretreatment NLR was significantly associated with PFS (P = .049) and OS (P = .023). In multivariable analysis, patients with a NLR of >3 were at significantly higher risk of tumor progress (hazard ratio 2.458; 95% confidence interval 1.186-5.093; P = .016) and death (hazard ratio 3.435; 95% CI 1.522-7.750; P = .003)than patients with a NLR of ⩽3.NLR may be an independent predictor of PFS and OS in castration-resistant prostate cancer patients treated with docetaxel. The findings require validation in further prospective, big sample-sized studies.


Assuntos
Antineoplásicos/uso terapêutico , Docetaxel/uso terapêutico , Linfócitos/citologia , Neutrófilos/citologia , Neoplasias de Próstata Resistentes à Castração/sangue , Neoplasias de Próstata Resistentes à Castração/tratamento farmacológico , Fatores Etários , Idoso , China , Intervalo Livre de Doença , Complexo IV da Cadeia de Transporte de Elétrons , Humanos , Estimativa de Kaplan-Meier , Contagem de Linfócitos , Masculino , Gradação de Tumores , Modelos de Riscos Proporcionais , Antígeno Prostático Específico , Neoplasias de Próstata Resistentes à Castração/mortalidade , Estudos Retrospectivos , Taxa de Sobrevida
11.
Arch Oral Biol ; 131: 105272, 2021 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-34600333

RESUMO

OBJECTIVE: This study aimed to characterize Neolithic human maxillary molars from archeological remains at the Jiaojia site, Shandong, China, and compare their ultrastructural features with sex and age-matched modern locals. DESIGN: Maxillary first (n = 86) and second (n = 80) molars in 5000-year-old individuals (n = 50) from the Jiaojia site were scanned by cone-beam computed tomography (CBCT). Sex and age-matched control groups were assigned from oral surgical patients at Shandong University. Images were analyzed for crown size, root length, root morphology, canal inter-orifice distances, mesiobuccal canal morphology, and second mesiobuccal (MB2) canal prevalence and location. Neolithic and modern values were compared statistically using Chi-squared and Mann-Whitney test at p < .05. RESULTS: Crown and root size were smaller, and canal inter-orifice distances were shorter in Neolithic maxillary molars than their modern counterparts. For mesiobuccal roots, Weine's Type I single canals were the most prevalent in Neolithic and modern first and second molars. MB2 canal prevalence were not significantly different (p > .05) in Neolithic (53.3%) or modern (60.5%) first molars, and Neolithic (11.3%) or modern (21.3%) second molars. But, MB2 prevalence was significantly higher for modern than ancient male first (p = .032) and second (p = .005) molars. Additionally, MB2 were located more mesially and closer to MB1 in Neolithic than modern molars. CONCLUSIONS: Maxillary molar root and canal morphology of ancient 5000-year-old remains at the Jiaojia site resemble that of local patients. A trend towards larger tooth size, and more dispersed MB2 canals over this short evolutionary period warrants additional investigation.


Assuntos
Dente Molar , Raiz Dentária , China , Tomografia Computadorizada de Feixe Cônico , Cavidade Pulpar/diagnóstico por imagem , Humanos , Masculino , Maxila/diagnóstico por imagem , Dente Molar/diagnóstico por imagem , Raiz Dentária/diagnóstico por imagem
12.
Environ Monit Assess ; 193(11): 706, 2021 Oct 08.
Artigo em Inglês | MEDLINE | ID: mdl-34623532

RESUMO

This study aimed to research the effects of forest (Pinus elliottii, slash pine) and shrub (Vitex trifolia) plantation on the soil microbial community in sandification land by using the Illumina Miseq sequencing of 16S rRNA and ITS rRNA genes and combined with the soil properties analysis to explore the driving factors. Finally, the results showed that the dominant bacterial phyla were Chloroflexi, Actinobacteria, Proteobacteria, and Acidobacteria; the shrub and forest plantation significantly increasing the proportion of Acidobacteria, while decreasing the proportion of Proteobacteria. For the fungal community, forest plantation was significantly changing the community structure at the phylum level that shifted from Ascomycota to Basidiomycota, and the ectomycorrhizal fungi take the most abundant with genus Rhizopogon predominant. The soil bacterial Chao1 and Shannon indices were significantly increased after revegetation, while the soil fungal Shannon diversity in the forest land that significantly correlated with soil total organic carbon and C/N was lower than that in the sandy and shrub land (p < 0.05). Besides, the bacterial and fungal communities were significantly affected by soil water content among all analyzed soil properties. Our results suggest that the revegetation significantly increasing the soil bacterial diversity that correlated with soil water content, total organic carbon, and available phosphorus, but there was no significant change in community structure. In contrast, slash pine plantation changes the fungal community structure and diversity dramatically. This change and possible succession of fungal community with stand age increasing may lead to the fragility of the plantation, which deserves continuous attention.


Assuntos
Micobioma , Solo , China , Monitoramento Ambiental , RNA Ribossômico 16S , Microbiologia do Solo
13.
Artigo em Chinês | MEDLINE | ID: mdl-34624954

RESUMO

In order to improve the clinical attention to the poisoning of chlorfenapyr, the diagnosis and treatment strategy of chlorfenapyr poisoning were discussed. This paper collected 4 cases of chlorfenapyr in the emergency department of the Second Hospital of Hebei Medical University and 4 cases of literature review, summarized the clinical characteristics of pesticide poisoning cases containing chlorfenapyr in China, and summarized and analyzed the clinical data of the cases. Seven of the 8 patients died from poisoning by chlorfenapyr. Exposure to chlorfenapyr through respiratory tract and digestive tract showed high mortality. Fever, hyperhidrosis, elevated muscle enzymes and progressive central nerve damage were its prominent clinical characteristics. Most of the initial symptoms of exposure were not serious. Some patients, especially those with low exposure dose, had a relatively stable stage with or without clinical diagnosis and treatment. In case of sweating, obvious fever and disturbance of consciousness, the condition would deteriorate rapidly, respiratory and circulatory failure and eventually die. With the increase of production capacity and market launch, people have more opportunities to be exposed to chlorfenapyr. It is urgent to strengthen the basic and clinical research of chlorfenapyr poisoning; Attention should be paid to the observation and treatment in the initial stable stage of poisoning, which can be used as a reference for the treatment of oxidative phosphoric acid dissolving coupling agent (sodium pentachlorophenol) poisoning.


Assuntos
Inseticidas , Piretrinas , China/epidemiologia , Humanos
14.
Artigo em Chinês | MEDLINE | ID: mdl-34624961

RESUMO

The quality of the water environment is one of the most important factors that can directly affect the health of human beings and other non-human species. The levels of the radionuclides in water environment are the key indicator while assessing the quality of water environment. Recently, with the development of the nuclear energy in China, the public people have paid a focus attention on the levels and the health risks of the radionuclides. This paper introduced the sources, the health effects, the health risk assessment methods and the current status of the health risk assessment study about the radionuclides, in order to provide basis for the health risk assessment of radionuclides in water environment and the protection of human health.


Assuntos
Radioisótopos , Água , China , Humanos , Radioisótopos/análise
15.
BMC Infect Dis ; 21(1): 1043, 2021 Oct 08.
Artigo em Inglês | MEDLINE | ID: mdl-34625036

RESUMO

BACKGROUND: Current guidelines support different management of cryptococcosis between severely immunodeficient and immunocompetent populations. However, few studies have focused on cryptococcosis patients with mild-to-moderate immunodeficiency. We performed this study to determine the clinical features of pulmonary (PC) and extrapulmonary cryptococcosis (EPC) and compared them among populations with different immune statuses to support appropriate clinical management of this public health threat. METHODS: All cases were reported by 14 tertiary teaching hospitals in Jiangsu Province, China from January 2013 to December 2018. The trends in incidence, demographic data, medical history, clinical symptoms, laboratory test indicators, imaging characteristics and diagnostic method of these patients were then stratified by immune status, namely immunocompetent (IC, patients with no recognized underlying disease or those with an underlying disease that does not influence immunity, such as hypertension), mild-to-moderate immunodeficiency (MID, patients with diabetes mellitus, end-stage liver or kidney disease, autoimmune diseases treated with low-dose glucocorticoid therapy, and cancer treated with chemotherapy) and severe immunodeficiency (SID, patients with acquired immunodeficiency syndrome, haematologic malignancies, solid organ transplantation or haematologic stem cell transplantation, idiopathic CD4 lymphocytosis, agranulocytosis, aggressive glucocorticoid or immunosuppressive therapy and other conditions or treatments that result in severe immunosuppression). RESULTS: The clinical data of 255 cryptococcosis patients were collected. In total, 66.3% of patients (169) were IC, 16.9% (43) had MID, and 16.9% (43) had SID. 10.1% of the patients (17) with IC were EPC, 18.6% of the patients (8) with MID were EPC, and 74.4% of patients (32) were EPC (IC/MID vs. SID, p < 0.001). Fever was more common in the SID group than in the IC and MID groups (69.8% vs. 14.8% vs. 37.2%, p < 0.001). Of chest CT scan, most lesions were distributed under the pleura (72.7%), presenting as nodules/lumps (90.3%) or consolidations (10.7%). Pleural effusion was more common in SID group compared to IC group (33.3% vs. 2.4%, p < 0.001). Positivity rate on the serum capsular polysaccharide antigen detection (CrAg) test was higher in the SID group than in the other two groups [100.0% vs. 84.4% (MID) vs. 78.2% (IC), p = 0.013]. Positivity rate on the serum CrAg test was also higher in cryptococcal meningitis patients than in PC patients (100.0% vs. 79.5%, p = 0.015). CONCLUSIONS: The clinical presentation of MID patients is intermediate between SID and IC patients and is similar to that of IC patients. The serum CrAg test is more sensitive for the identification of SID or EPC patients.


Assuntos
Criptococose , Síndromes de Imunodeficiência , Pneumopatias , Meningite Criptocócica , China/epidemiologia , Criptococose/diagnóstico , Criptococose/epidemiologia , Humanos
16.
Zhongguo Shi Yan Xue Ye Xue Za Zhi ; 29(5): 1561-1565, 2021 Oct.
Artigo em Chinês | MEDLINE | ID: mdl-34627440

RESUMO

OBJECTIVE: To perform dried blood spots thalassemia gene detection in patients with positive blood phenotypes by microarray technology, and evaluate its value in clinical detection. METHODS: DNA samples were extracted from dried blood spots of 410 patients. Microarray technology was used to detect 3 deletion and 3 non-deletion types of α-thalassemia and 19 ß-thalassemia point mutations which were common gene mutions in China. RESULTS: There were 357 positive cases in all the 410 tested samples with the positive rate 87.07%, among which 299 cases (72.93%) carried deletion or point mutations of α-thalassemia, 29 cases (7.07%) carried point mutations of ß-thalassemia and 29 cases (7.07%) carried gene mutations of complex αß-thalassemia syndrome. The mutations of α-thalassemia were involved with --SEA heterozygous deletion (177 cases, 59.2%), αCS heterozygote (60 cases, 20.07%) and several other genotypes. The common mutations of ß- thalassemia were involved with ßCD41-42 heterozygote (10 cases, 34.48%) and ßCD17 heterozygote (9 cases, 31.03%). The mutations of complex αß-thalassemia syndrome were mainly involved with --SEA/αα+ßCD17/ßN (7 cases, 24.14%), αCSα/αα + ßCD41-42/ßN (3 cases, 10.34%) and -α4.2/αα + ßCD17/ßN (3 cases, 10.34%). CONCLUSION: The most common genetic mutations are --SEA for α-thalassemia and CD41-42 for ß-thalassemia in Liuzhou, Guangxi Zhuang Autonomous Region. A and ß-thalassemia can be detected at the same time by microarray chip technology in a high throughput manner.


Assuntos
Talassemia alfa , Talassemia beta , China , Humanos , Mutação , Análise de Sequência com Séries de Oligonucleotídeos , Talassemia alfa/genética , Talassemia beta/genética
17.
Front Public Health ; 9: 752481, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34616710

RESUMO

Economic shocks from COVID-19, coupled with ongoing US-China tensions, have raised debates around supply chain (or global value chain) organisation, with China at the centre of the storm. However, quantitative studies that consider the global and economy-wide impacts of rerouting supply chains are limited. This study examines the economic and emissions impacts of reorganising supply chains, using Australia-China trade as an example. It augments the Hypothetical Extraction Method by replacing traditional Input-Output analysis with a Computable General Equilibrium analysis. The estimation results demonstrate that in both exports and imports, a trade embargo between Australia and China - despite being compensated for by alternative supply chains-will cause gross domestic production losses and emissions increases for both countries and the world overall. Moreover, even though all other economies gain from the markets left by China, many of them incur overall gross domestic production losses and emission increases. The finding that the Association of Southeast Asian Nations and India may also suffer from an Australia-China trade embargo, despite a gain in trade volume, suggests that no country should add fuel to the fire. The results suggest that countries need to defend a rules-based trading regime and jointly address supply chain challenges.


Assuntos
COVID-19 , Austrália , China , Comércio , Humanos , SARS-CoV-2
18.
Front Public Health ; 9: 720512, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34616706

RESUMO

Ensuring the well-being of persons with disabilities (PWDs) is a priority in the public sector during the coronavirus disease 2019 (COVID-19) pandemic. To contain this unprecedented public crisis in China, a set of nationwide anti-epidemic discourse systems centered on war metaphors has guided the epidemic's prevention and control. While the public is immersed in the joy brought by the stage victory, most ignore the situation of the disadvantaged PWDs. Accordingly, this study adopts and presents a qualitative research method to explore the impact of war metaphors on PWDs. The results showed that while there was some formal and informal support for PWDs during this period, they were increasingly marginalized. Owing to the lack of a disability lens and institutional exclusion, PWDs were placed on the margins of the epidemic prevention and control system like outsiders. Affected by pragmatism under war metaphors, PWDs are regarded as non-contributory or inefficient persons; therefore, they are not prioritized and are thus placed into a state of being voiceless and invisible. This research can provide inspiration for improving public services for PWDs in the context of COVID-19.


Assuntos
COVID-19 , Pessoas com Deficiência , China/epidemiologia , Humanos , Metáfora , Pandemias/prevenção & controle , SARS-CoV-2
19.
Environ Monit Assess ; 193(11): 697, 2021 Oct 07.
Artigo em Inglês | MEDLINE | ID: mdl-34618243

RESUMO

Short-duration high-strength human tourism activities (SHHTA) can result in more air pollution emissions owing to increase motor vehicle usage, energy consumption and cooking fume emissions. Because of the strong uncertainty of human tourism behaviour, it is difficult to accurately assess the impact of SHHTA on air quality of natural scenic spots. To overcome this difficulty, we propose a novel ensemble empirical mode decomposition and detrended cross-correlation analysis (EEMD-DCCA) model to assess the influence of short-duration high-strength human tourism activities (SHHTA) on air quality. Zhangjiajie in China was selected as the study area. Hourly concentrations of NO2 were analysed from 1 January 2016 to 31 December 2018 at two monitoring sites, in an urban area and a scenic spot. Through EEMD, the main modes of NO2 with short-duration high-frequency were obtained for both sites. The DCCA method was used to study the cross-correlation relationship between high-frequency modes of NO2 for the urban area and scenic spot. The results show that high-frequency modes of NO2 between the two sites displayed long-range cross-correlation at the 24-h time scale. Furthermore, the quantitative impacts of meteorological factors (e.g. precipitation, temperature, and wind speed) on the DCCA exponent for high-frequency modes of NO2 at the two sites were investigated. The novel model proposed in this study is not restricted by the uncertainty of pollution emission inventory. The relationship between meteorological factors and DCCA exponents corresponds to the hypothesis that NO2 pollution of the natural scenic spot mainly came from SHHTA.


Assuntos
Poluentes Atmosféricos , Poluição do Ar , Poluentes Atmosféricos/análise , Poluição do Ar/análise , China , Monitoramento Ambiental , Humanos , Turismo
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