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2.
Pediatr Dermatol ; 41(2): 243-246, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38413004

RESUMO

BACKGROUND: Idiopathic aseptic facial granuloma (IAFG) is an underrecognized pediatric skin disease, currently considered within the spectrum of rosacea. It usually manifests as a solitary, reddish, asymptomatic nodule on the cheek that resolves spontaneously. METHODS: Retrospective and descriptive observational study of 43 pediatric patients with a clinical diagnosis of IAFG, followed between 2004 and 2022, at two general hospitals in Argentina. RESULTS: IAFG predominated in girls (65%) and the average age of onset was about 6 years. A single asymptomatic nodule was seen in 79% of patients. The most common localization was the cheek (58%) followed by lower eyelids (41%). Family history of rosacea was present in 16% of patients. A concomitant diagnosis of rosacea and periorificial dermatitis was made in 14% and 9% of our population, respectively. Past or present history of chalazia was detected in 42% of the children. IAFG diagnosis was mainly clinical (88% of cases). Oral antibiotics were the most common indicated treatment (84%). Complete healing was achieved by the majority, but 18% of those with eyelid compromise healed with scars. CONCLUSIONS: IAFG is a benign pediatric condition that physicians should recognize in order to manage correctly. We herein refer to a particular morphologic aspect of IAFG lesions affecting the lower eyelids, where nodules adopt a linear distribution and have a higher probability of involute leaving a scar. Also, we consider that the concomitant findings of rosacea, periorificial dermatitis and chalazia in our patients, reinforce the consideration of IAFG within the spectrum of rosacea.


Assuntos
Calázio , Doenças do Tecido Conjuntivo , Dermatite , Dermatoses Faciais , Rosácea , Feminino , Humanos , Criança , Estudos Retrospectivos , Calázio/complicações , Calázio/diagnóstico , Dermatoses Faciais/diagnóstico , Dermatoses Faciais/tratamento farmacológico , Dermatoses Faciais/patologia , Granuloma/diagnóstico , Granuloma/tratamento farmacológico , Rosácea/diagnóstico , Rosácea/tratamento farmacológico , Rosácea/epidemiologia
3.
Skin Res Technol ; 30(1): e13540, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38186043

RESUMO

BACKGROUND: Sensitive skin is a common condition affecting a significant proportion of the population, and there is a growing demand for effective and safe management. AIM: To evaluate the efficacy and safety of a cream containing panthenol, prebiotics, and probiotic lysate as an optimal care for facial sensitive skin. METHODS: A total of 110 participants (64 in group A and 46 in group B) with facial sensitive skin applied the cream twice daily for 28 days. Group A evaluated their sensitive skin, product efficacy, and product use experience at D0 (15 min), D1, D14, and D28. In group B, skin barrier function-related indicators were measured at baseline and on D1, D7, D14, and D28. Dermatologists evaluated tolerance for all participants. RESULTS: After 28 days of use, in group A, 100% of participants reported mildness and comfort with product use. Participants demonstrated significant improvements in skin barrier function-related indicators, including increased stratum corneum moisture content, reduced erythema index, elevated sebum content, decreased trans-epidermal water loss, and diminished skin redness parameter a* value (all p < 0.05). Dermatologist evaluations revealed excellent tolerance among all participants. CONCLUSION: The panthenol-enriched cream with prebiotics and probiotic lysate exhibited substantial clinical efficacy in ameliorating facial sensitive skin conditions, coupled with a high safety profile.


Assuntos
Dermatoses Faciais , Probióticos , Humanos , Prebióticos/efeitos adversos , Probióticos/efeitos adversos , Ácido Pantotênico , Emolientes
4.
JAMA Dermatol ; 160(4): 462-463, 2024 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-38294808

RESUMO

This case report describes multiple solitary open black comedones located bilaterally on the malar cheeks and temples as well as yellowish, smooth-surfaced papulonodular lesions in close association with the comedones.


Assuntos
Dermatoses Faciais , Humanos
10.
Eur J Dermatol ; 33(4): 419-425, 2023 Aug 01.
Artigo em Inglês | MEDLINE | ID: mdl-37823493

RESUMO

BACKGROUND: Therapeutic make-up has previously been proven to be efficacious in improving the quality of life of patients with facial dermatoses, but its efficacy has only been assessed in the short term (less than one month). OBJECTIVES: This study aimed to determine whether the effect of therapeutic make-up on patients' quality of life persists in the longer term, i.e., after one year. MATERIALS & METHODS: This study included 53 patients who benefited from a therapeutic make-up consultation in the context of various facial dermatoses (pigmentation disorders, scars, acne, rosacea, eczema, adverse events of chemotherapy, etc.). Patients were asked to complete a quality-of-life questionnaire to obtain the Skindex score at baseline, and one month (M1) and one year (M12) after the first consultation. The difference in scores between baseline and M12 was calculated and Student's t-test was used to assess the significance of the values. RESULTS: Our results showed a significant difference (p<0.001) with an improvement in quality-of-life score by more than 10% between baseline and M12, for all the dimensions of the score (Emotion, Symptoms and Functioning). Based on the subgroup analysis, this score particularly improved for patients suffering with acne or rosacea (p=0.009) and scars (p=0.43), as well as for younger patients (<30 years old) (p=0.009). CONCLUSION: This is the first study to demonstrate a persistent long-term effect of therapeutic make-up on the quality of life of patients with facial dermatoses.


Assuntos
Acne Vulgar , Dermatoses Faciais , Rosácea , Humanos , Adulto , Cicatriz/patologia , Qualidade de Vida , Acne Vulgar/tratamento farmacológico , Rosácea/tratamento farmacológico , Dermatoses Faciais/tratamento farmacológico
11.
Pediatr Dermatol ; 40(6): 1064-1067, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37667982

RESUMO

Aseptic facial granuloma is a rare pediatric disease, presenting with asymptomatic facial nodules on the cheeks or the eyelids and may represent a form of granulomatous rosacea in children. In this retrospective case series, 12 children with aseptic facial granuloma were treated with oral macrolides (erythromycin or roxithromycin) resulting in a healing of the lesions within a mean treatment time of 5.25 months with no recurrences. The treatment was mainly well tolerated. Oral macrolides may be effective in the treatment of patients with aseptic facial granuloma.


Assuntos
Dermatoses Faciais , Rosácea , Criança , Humanos , Macrolídeos/uso terapêutico , Estudos Retrospectivos , Antibacterianos/uso terapêutico , Granuloma/tratamento farmacológico , Granuloma/patologia , Rosácea/tratamento farmacológico , Bochecha/patologia , Dermatoses Faciais/tratamento farmacológico , Dermatoses Faciais/patologia
12.
Skin Res Technol ; 29(9): e13466, 2023 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-37753681

RESUMO

BACKGROUND: Polynucleotides (PN) are increasingly used for the treatment of facial erythema in the Republic of Korea. However, there are limited pre-clinical and clinical data on the efficacy of polynucleotides for facial erythema. In this study, we investigated the current practice and perceived effectiveness of polynucleotide treatment for facial erythema among cosmetic physicians. METHODS: By conducting a survey among clinicians who use PN in clinical practice, we explored the current practices and assessed the perceived effectiveness of polynucleotides in treating facial erythema. RESULTS: A total of 557 physicians who used polynucleotides for facial erythema participated in the survey. Polynucleotides were used by 84.4%, 66.4%, and 47.4% of physicians for facial erythema caused by inflammatory facial dermatosis, repeated laser/microneedle radiofrequency, and steroid overuse, respectively. Among those users, 88.1%, 90%, and 83.7% respectively in those same categories answered that polynucleotides were "highly effective" or "effective." Furthermore, they agreed that polynucleotides have the following properties: wound healing/regeneration (95.8%), protection of skin barrier (92.2%), hydration (90.5%), vascular stabilization (81.0%), and anti-inflammation (79.5%). CONCLUSION: Our findings showed that cosmetic physicians in the Republic of Korea have used PN as a part of combination treatment for facial erythema resulting from inflammatory facial dermatosis and repeated laser/ microneedle radiofrequency, rather than from steroid overuse. Also, most clinicians agreed that PN was effective for treatment of facial erythema. Given the lack of pre-clinical and clinical trial evidence, the empirical responses of practicing physicians provide useful information to guide clinical practice and further research.


Assuntos
Cosméticos , Dermatoses Faciais , Humanos , Resultado do Tratamento , Eritema/tratamento farmacológico , Eritema/etiologia , Cicatrização , Esteroides
15.
Tidsskr Nor Laegeforen ; 143(11)2023 08 15.
Artigo em Norueguês | MEDLINE | ID: mdl-37589351

RESUMO

BACKGROUND: Lyme disease after a tick bite often presents as erythema migrans, yet less frequent variants of this disease, such as Borrelia lymphocytoma, multiple erythema migrans and neuroborreliosis, are also seen occasionally. CASE PRESENTATION: We report a case of a tick-bitten child who first presented with an indistinct macular erythema around the left eye and a more distinct macular erythema on and around the left ear. The next day, she developed a facial palsy. INTERPRETATION: The case was interpreted as facial multiple erythema migrans and Borrelia lymphocytoma on the ear, followed by neuroborreliosis. The diagnosis of lymphocytoma was made from clinical findings and PCR of skin biopsy. She recovered quickly after intravenous ceftriaxone and is now healthy.


Assuntos
Doença de Lyme , Pseudolinfoma , Dermatopatias Bacterianas , Criança , Feminino , Humanos , Otopatias/etiologia , Eritema Migrans Crônico/etiologia , Dermatoses Faciais/etiologia , Paralisia Facial/etiologia , Neuroborreliose de Lyme/etiologia , Pseudolinfoma/diagnóstico , Picadas de Carrapatos/complicações , Doença de Lyme/complicações , Doença de Lyme/diagnóstico , Dermatopatias Bacterianas/diagnóstico
16.
18.
Skin Res Technol ; 29(6): e13344, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37357648

RESUMO

BACKGROUND: Facial erythema is a common problem among patients visiting dermatologists. However, data on the clinical characteristics of facial erythema in healthy people are lacking. We aimed to compare and analyze the severity and pattern of facial vascularity in healthy subjects based on their age and gender. MATERIALS AND METHODS: This study included 198 Korean volunteers (126 females and 72 males) with Fitzpatrick skin types II, III, or IV. Fourteen different anatomical areas on the face were divided into facial erythema units. Each unit was scored from one (least erythematous) to five (most erythematous) according to the observed level of erythema on the red images implemented as hemoglobin content. We also evaluated the presence of facial telangiectatic macules. RESULTS: On average, the perinasal, nasal, and cheek units were the most hypervascular regions. In contrast, the degree of facial erythema was lowest in the labial (perioral), neck, and temporal regions. The average value of erythema was higher in males than in females. Additionally, the severity of erythema tended to increase with age. In both males and females, the number of telangiectatic macules increased with age. CONCLUSIONS: We analyzed the clinical characteristics of erythema in healthy subjects with Fitzpatrick skin types II, III, or IV in the Korean population. This study is expected to be used to identify the neurovascular pathogenesis of the most common regions of facial dermatosis in the future.


Assuntos
Face , Dermatoses Faciais , Telangiectasia , Feminino , Humanos , Masculino , Povo Asiático , Eritema/patologia , República da Coreia/epidemiologia , Voluntários Saudáveis , Face/irrigação sanguínea
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