Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 20 de 64.329
Filtrar
1.
Med Sci Monit ; 30: e943955, 2024 Jul 10.
Artigo em Inglês | MEDLINE | ID: mdl-38985697

RESUMO

Deep vein thrombosis (DVT) of the lower extremities is divided into 2 categories according to the extent of thrombosis involvement. Thrombosis involving the popliteal vein, femoral vein, and iliac vein is classified as proximal DVT, while thrombosis involving the anterior tibial vein, posterior tibial vein, peroneal vein, and calf muscles vein is regarded as distal DVT. There are updated guidelines for the anticoagulant treatment for proximal DVT, but the best anticoagulant treatment for distal DVT is still controversial, especially for isolated calf muscular vein thrombosis (CMVT). The risk of isolated CMVT extending to the proximal deep veins and developing into pulmonary embolism is lower than with distal DVT. Some scholars believe that isolated CMVT has the risk of evolving into proximal deep vein thrombosis and pulmonary embolism, and active early anticoagulation therapy can reduce the risk and benefit patients. In addition, based on the characteristics of CMVT and the bleeding risk of anticoagulation therapy, some studies have recommended use of non-anticoagulation methods such as compression therapy. There is still a lack of multicenter, big-data, randomized, controlled trials on the benefits or risks of anticoagulation therapy. Among scholars who support anticoagulation therapy, there is still a lack of consensus on the optimal duration. This article reviews the current evidence on anticoagulant therapy for patients with isolated CMVT and how long the anticoagulation course should be if anticoagulation is required. Our research will provide a theoretical basis for subsequent research. More prospective studies with larger sample sizes are needed to provide more clinical evidence.


Assuntos
Anticoagulantes , Perna (Membro) , Trombose Venosa , Humanos , Anticoagulantes/uso terapêutico , Trombose Venosa/tratamento farmacológico , Perna (Membro)/irrigação sanguínea , Músculo Esquelético/irrigação sanguínea , Embolia Pulmonar/tratamento farmacológico
2.
PLoS One ; 19(7): e0304606, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38990910

RESUMO

OBJECTIVE: To compare whole-body kinematics, leg muscle activity, and discomfort while performing a 10-min carrying task with and without a passive upper-body exoskeleton (CarrySuitⓇ), for both males and females. BACKGROUND: Diverse commercial passive exoskeletons have appeared on the market claiming to assist lifting or carrying task. However, evidence of their impact on kinematics, muscle activity, and discomfort while performing these tasks are necessary to determine their benefits and/or limitations. METHOD: Sixteen females and fourteen males carried a 15kg load with and without a passive exoskeleton during 10-min over a round trip route, in two non-consecutive days. Whole-body kinematics and leg muscle activity were evaluated for each condition. In addition, leg discomfort ratings were quantified before and immediately after the task. RESULTS: The gastrocnemius and vastus lateralis muscle activity remained constant over the task with the exoskeleton. Without the exoskeleton a small decrease of gastrocnemius median activation was observed regardless of sex, and a small increase in static vastus lateralis activation was observed only for females. Several differences in sagittal, frontal, and transverse movements' ranges of motion were found between conditions and over the task. With the exoskeleton, ROM in the sagittal plane increased over time for the right ankle and pelvis for both sexes, and knees for males only. Thorax ROMs in the three planes were higher for females only when using the exoskeleton. Leg discomfort was lower with the exoskeleton than without. CONCLUSION: The results revealed a positive impact on range of motion, leg muscle activity, and discomfort of the tested exoskeleton.


Assuntos
Exoesqueleto Energizado , Perna (Membro) , Músculo Esquelético , Humanos , Masculino , Feminino , Fenômenos Biomecânicos , Adulto , Músculo Esquelético/fisiologia , Perna (Membro)/fisiologia , Adulto Jovem , Amplitude de Movimento Articular/fisiologia , Eletromiografia , Suporte de Carga/fisiologia
3.
Physiol Rep ; 12(13): e16144, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38991985

RESUMO

Previous research has demonstrated that oral contraceptive (OC) users have enhanced cardiorespiratory responses to arm metaboreflex activation (i.e., postexercise circulatory occlusion, PECO) and attenuated pressor responses to leg passive movement (PM) compared to non-OC users (NOC). We investigated the cardiorespiratory responses to arm or leg metaboreflex and mechanoreflex activation in 32 women (OC, n = 16; NOC, n = 16) performing four trials: 40% handgrip or 80% plantarflexion followed by PECO and arm or leg PM. OC and NOC increased mean arterial pressure (MAP) similarly during handgrip, plantarflexion and arm/leg PECO compared to baseline. Despite increased ventilation (VE) during exercise, none of the women exhibited higher VE during arm or leg PECO. OC and NOC similarly increased MAP and VE during arm or leg PM compared to baseline. Therefore, OC and NOC were similar across pressor and ventilatory responses to arm or leg metaboreflex and mechanoreflex activation. However, some differences due to OC may have been masked by disparities in muscle strength. Since women increase VE during exercise, we suggest that while women do not display a ventilatory response to metaboreflex activation (perhaps due to not reaching a theoretical metabolite threshold to stimulate VE), the mechanoreflex may drive VE during exercise in women.


Assuntos
Anticoncepcionais Orais , Exercício Físico , Reflexo , Humanos , Feminino , Exercício Físico/fisiologia , Adulto , Anticoncepcionais Orais/farmacologia , Força da Mão , Perna (Membro)/fisiologia , Pressão Sanguínea/fisiologia , Braço/fisiologia , Adulto Jovem
5.
J Neuroeng Rehabil ; 21(1): 116, 2024 Jul 12.
Artigo em Inglês | MEDLINE | ID: mdl-38997727

RESUMO

OBJECTIVE: This study explored the impact of one session of low-pressure leg blood flow restriction (BFR) during treadmill walking on dual-task performance in older adults using the neurovisceral integration model framework. METHODS: Twenty-seven older adults participated in 20-min treadmill sessions, either with BFR (100 mmHg cuff pressure on both thighs) or without it (NBFR). Dual-task performance, measured through light-pod tapping while standing on foam, and heart rate variability during treadmill walking were compared. RESULTS: Following BFR treadmill walking, the reaction time (p = 0.002) and sway area (p = 0.012) of the posture dual-task were significantly reduced. Participants exhibited a lower mean heart rate (p < 0.001) and higher heart rate variability (p = 0.038) during BFR treadmill walking. Notably, BFR also led to band-specific reductions in regional brain activities (theta, alpha, and beta bands, p < 0.05). The topology of the EEG network in the theta and alpha bands became more star-like in the post-test after BFR treadmill walking (p < 0.005). CONCLUSION: BFR treadmill walking improves dual-task performance in older adults via vagally-mediated network integration with superior neural economy. This approach has the potential to prevent age-related falls by promoting cognitive reserves.


Assuntos
Frequência Cardíaca , Caminhada , Humanos , Idoso , Masculino , Feminino , Caminhada/fisiologia , Frequência Cardíaca/fisiologia , Teste de Esforço , Encéfalo/fisiologia , Encéfalo/diagnóstico por imagem , Encéfalo/irrigação sanguínea , Fluxo Sanguíneo Regional/fisiologia , Desempenho Psicomotor/fisiologia , Perna (Membro)/fisiologia
6.
J Coll Physicians Surg Pak ; 34(7): 817-821, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38978247

RESUMO

OBJECTIVE: To determine the frequency and pattern of different aetiologies of leg pain among patients visiting vascular surgery clinics. STUDY DESIGN: Cross-sectional study. Place and Duration of the Study: Vascular Surgery Clinics of the Aga Khan University Hospital, Karachi, Pakistan, between February 2021 and June 2023. METHODOLOGY: This study examined patients presenting with leg pain for the first time at vascular surgery clinics. The socio-demographic and clinical data including the clinical symptoms, physical examination findings, and management of leg pain were noted using a specially designed proforma. RESULTS: In a total of 142 patients (200 limbs), 82 (57.7%) were females and 60 (42.3%) were males, with a mean age of 46.8 ± 15.1 years. The patients' mean body mass index (BMI) was 30.2 ± 7.9 kg/m2. Ninety-one (64.1%) patients had a predominantly standing job compared to 51 (35.9%) patients who had a predominantly sitting job. The most common aetiology of leg pain was chronic venous insufficiency (CVI), diagnosed in 107 (53.5%) patients, followed by neurogenic pain [41 (20.5%)], musculoskeletal pain including knee osteoarthritis [30 (15.0%)], and arterial insufficiency [22 (11.0%)].  Conclusion: CVI followed by neuropathic pain was the leading cause of leg pain in vascular surgery clinics at a tertiary care hospital. KEY WORDS: Chronic venous insufficiency, Arterial insufficiency, Vascular surgery, Leg pain, Musculoskeletal pain, Neuralgia.


Assuntos
Perna (Membro) , Humanos , Feminino , Masculino , Pessoa de Meia-Idade , Estudos Transversais , Paquistão/epidemiologia , Adulto , Perna (Membro)/irrigação sanguínea , Procedimentos Cirúrgicos Vasculares , Dor/etiologia , Dor/epidemiologia , Neuralgia/etiologia , Neuralgia/epidemiologia , Idoso , Dor Musculoesquelética/epidemiologia , Dor Musculoesquelética/etiologia
7.
Scand J Med Sci Sports ; 34(7): e14688, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38973702

RESUMO

AIM: To assess the impact of endurance training on skeletal muscle release of H+ and K+. METHODS: Nine participants performed one-legged knee extension endurance training at moderate and high intensities (70%-85% of Wpeak), three to four sessions·week-1 for 6 weeks. Post-training, the trained and untrained (control) leg performed two-legged knee extension at low, moderate, and high intensities (40%, 62%, and 83% of Wpeak) in normoxia and hypoxia (~4000 m). The legs were exercised simultaneously to ensure identical arterial inflow concentrations of ions and metabolites, and identical power output was controlled by visual feedback. Leg blood flow was measured (ultrasound Doppler), and acid-base variables, lactate- and K+ concentrations were assessed in arterial and femoral venous blood to study K+ and H+ release. Ion transporter abundances were assessed in muscle biopsies. RESULTS: Lactate-dependent H+ release was similar in hypoxia to normoxia (p = 0.168) and was lower in the trained than the control leg at low-moderate intensities (p = 0.060-0.006) but similar during high-intensity exercise. Lactate-independent and total H+ releases were higher in hypoxia (p < 0.05) and increased more with power output in the trained leg (leg-by-power output interactions: p = 0.02). K+ release was similar at low intensity but lower in the trained leg during high-intensity exercise in normoxia (p = 0.024) and hypoxia (p = 0.007). The trained leg had higher abundances of Na+/H+ exchanger 1 (p = 0.047) and Na+/K+ pump subunit α (p = 0.036). CONCLUSION: Moderate- to high-intensity endurance training increases lactate-independent H+ release and reduces K+ release during high-intensity exercise, coinciding with increased Na+/H+ exchanger 1 and Na+/K+ pump subunit α muscle abundances.


Assuntos
Treino Aeróbico , Hipóxia , Ácido Láctico , Perna (Membro) , Músculo Esquelético , Potássio , Humanos , Potássio/metabolismo , Potássio/sangue , Hipóxia/metabolismo , Masculino , Músculo Esquelético/metabolismo , Músculo Esquelético/irrigação sanguínea , Perna (Membro)/irrigação sanguínea , Adulto , Ácido Láctico/sangue , Adulto Jovem , Prótons , Fluxo Sanguíneo Regional , ATPase Trocadora de Sódio-Potássio/metabolismo , Exercício Físico/fisiologia , Trocador 1 de Sódio-Hidrogênio/metabolismo
8.
Nat Med ; 30(7): 2010-2019, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38951635

RESUMO

For centuries scientists and technologists have sought artificial leg replacements that fully capture the versatility of their intact biological counterparts. However, biological gait requires coordinated volitional and reflexive motor control by complex afferent and efferent neural interplay, making its neuroprosthetic emulation challenging after limb amputation. Here we hypothesize that continuous neural control of a bionic limb can restore biomimetic gait after below-knee amputation when residual muscle afferents are augmented. To test this hypothesis, we present a neuroprosthetic interface consisting of surgically connected, agonist-antagonist muscles including muscle-sensing electrodes. In a cohort of seven leg amputees, the interface is shown to augment residual muscle afferents by 18% of biologically intact values. Compared with a matched amputee cohort without the afferent augmentation, the maximum neuroprosthetic walking speed is increased by 41%, enabling equivalent peak speeds to persons without leg amputation. Further, this level of afferent augmentation enables biomimetic adaptation to various walking speeds and real-world environments, including slopes, stairs and obstructed pathways. Our results suggest that even a small augmentation of residual muscle afferents restores biomimetic gait under continuous neuromodulation in individuals with leg amputation.


Assuntos
Amputação Cirúrgica , Amputados , Membros Artificiais , Biomimética , Biônica , Marcha , Humanos , Marcha/fisiologia , Biomimética/métodos , Masculino , Pessoa de Meia-Idade , Adulto , Feminino , Músculo Esquelético/inervação , Caminhada , Perna (Membro)/cirurgia
10.
Nutrients ; 16(11)2024 May 26.
Artigo em Inglês | MEDLINE | ID: mdl-38892555

RESUMO

Dietary nitrate (NO3-) supplementation is known to enhance nitric oxide (NO) activity and acts as a vasodilator. In this randomized crossover study, we investigated the effect of inorganic NO3- supplementation on the changes in calf venous volume during postural change and subsequent skeletal muscle pump activity. Fifteen healthy young adults were assigned to receive beetroot juice (BRJ) or a NO3--depleted control beverage (prune juice: CON). Two hours after beverage consumption, the changes in the right calf volume during postural change from supine to upright and a subsequent right tiptoe maneuver were measured using venous occlusion plethysmography. The increase in calf volume from the supine to upright position (total venous volume [VV]) and the decrease in calf volume during the right tiptoe maneuver (venous ejection volume [Ve]) were calculated. Plasma NO3- concentration was higher in the BRJ group than in the CON group 2 h after beverage intake (p < 0.05). However, VV and Ve did not differ between CON and BRJ. These results suggest that acute intake of BRJ may enhance NO activity via the NO3- → nitrite → NO pathway but does not change calf venous pooling due to a postural change or the calf venous return due to skeletal muscle pump activity in healthy young adults.


Assuntos
Beta vulgaris , Estudos Cross-Over , Suplementos Nutricionais , Perna (Membro) , Músculo Esquelético , Nitratos , Humanos , Músculo Esquelético/efeitos dos fármacos , Nitratos/administração & dosagem , Adulto Jovem , Masculino , Feminino , Perna (Membro)/irrigação sanguínea , Adulto , Postura/fisiologia , Sucos de Frutas e Vegetais , Óxido Nítrico/metabolismo , Volume Sanguíneo/efeitos dos fármacos , Voluntários Saudáveis
11.
Int Wound J ; 21(7): e14901, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38937919

RESUMO

The uncertainty concerning the physiological effects of compression bandaging on the peripheral blood flow is a challenge for healthcare professionals. The main objective was to determine the haemodynamic impact on the distal posterior tibial artery after the application of a high-compression leg multicomponent bandaging system using 4D flow magnetic resonance imaging. Leg dominance disparities of the posterior tibial artery before and after the application of the compressive bandage were also analysed. Twenty-eight healthy female volunteers were recruited (mean: 25.71, standard deviation: 4.74 years old) through a non-probability convenience sampling. The 4D flow magnetic resonance imaging of the distal tibial posterior artery was performed in all participants, first under standard resting conditions and after the application of a compression bandage in the leg. When the strong compressive bandage was applied, the area of the assessed artery decreased by 14.2%, whilst the average speed increased by 19.6% and the flow rate increased by 184.8%. There were differences between the haemodynamic parameters of both legs according to dominance, being statistically significantly lower in the dominant leg. The application of strong compressive bandaging significantly increases the arterial flow and mean velocity in the distal segment of the posterior tibial artery, in healthy volunteers by 4D flow magnetic resonance imaging. In this study, leg dominance influenced some of the haemodynamic parameters. According to the results, leg compression bandages cannot be contraindicated in vascular ulcers with arterial compromise.


Assuntos
Bandagens Compressivas , Hemodinâmica , Imageamento por Ressonância Magnética , Artérias da Tíbia , Humanos , Feminino , Artérias da Tíbia/diagnóstico por imagem , Artérias da Tíbia/fisiopatologia , Adulto , Imageamento por Ressonância Magnética/métodos , Hemodinâmica/fisiologia , Adulto Jovem , Voluntários Saudáveis , Perna (Membro)/irrigação sanguínea
14.
J Appl Physiol (1985) ; 137(1): 85-98, 2024 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-38841756

RESUMO

Similar to nonamputees, female athletes with unilateral transtibial amputation (TTA) using running-specific leg prostheses (RSPs) may have worse running economy and higher rates of running-related injury than male athletes. Optimizing RSP configuration for female athletes could improve running economy and minimize biomechanical asymmetry, which has been associated with running-related injury. Nine females with a TTA ran at 2.5 m/s while we measured metabolic rates and ground reaction forces. Subjects used an RSP with a manufacturer-recommended stiffness category, one category less stiff and two categories less stiff than recommended. Use of an RSP two categories less stiff resulted in 3.0% lower net metabolic power (P = 0.04), 7.8% lower affected leg stiffness (P = 6.01 × 10-4), increased contact time asymmetry (P = 0.04), and decreased stance average vertical ground reaction force asymmetry (P = 0.04) compared with a recommended stiffness category RSP. Lower RSP stiffness (kN/m) values were associated with lower net metabolic power (P = 0.02), lower affected leg stiffness (P = 1.36 × 10-4), longer affected leg contact time (P = 1.46 × 10-4), and similar affected leg peak and stance-average vertical ground reaction force compared with higher RSP stiffness values. Subjects then used the RSP stiffness category that elicited the lowest net metabolic power with 100 g, 200 g, and 300 g added distally. We found no significant effects of added mass on net metabolic power, biomechanics, or asymmetry. These results suggest that female runners with a TTA could decrease metabolic power during running while minimizing biomechanical asymmetries, which have been associated with running-related injury, by using an RSP two categories less stiff than manufacturer recommended.NEW & NOTEWORTHY Females with unilateral transtibial amputation can improve running performance through reductions in net metabolic power by using a running-specific prosthesis (RSP) that is less stiff than manufacturer-recommended. Lower RSP stiffness values are associated with greater leg stiffness and contact time asymmetry, and lower stance-average vertical ground reaction force asymmetry. However, we found that adding mass to the RSP did not affect net metabolic power and stance-phase biomechanical asymmetries during running.


Assuntos
Amputação Cirúrgica , Membros Artificiais , Perna (Membro) , Corrida , Humanos , Feminino , Corrida/fisiologia , Adulto , Fenômenos Biomecânicos/fisiologia , Perna (Membro)/fisiologia , Amputados , Adulto Jovem , Desenho de Prótese , Atletas , Pessoa de Meia-Idade , Metabolismo Energético/fisiologia
15.
Sensors (Basel) ; 24(12)2024 Jun 07.
Artigo em Inglês | MEDLINE | ID: mdl-38931483

RESUMO

The Orthelligent Pro sensor is a practicable, portable measuring instrument. This study assessed the validity and reliability of this sensor in measuring single-leg countermovement jumps. Fifty healthy athletic adults participated in two measurement sessions a week apart in time. They performed single-leg countermovement jumps on the force plate while wearing the Orthelligent Pro sensor on their lower leg. During the first measurement session, Tester 1 invited the participants to make three single-leg countermovement jumps; subsequently, Tester 2 did the same. For assessing the sensor's intratester reliability, Tester 1 again invited the participants to make three single-leg countermovement jumps during the second measurement session. The sensor's validity was assessed by using the force plate results as the gold standard. To determinate the agreement between two measurements, Bland-Altman plots were created. The intertester reliability (ICC = 0.99; 0.97) and intratester reliability (ICC = 0.96; 0.82) were both excellent. The validity calculated (i) on the basis of the mean value of three jumps and (ii) on the basis of the maximum value of three jumps was very high, but it showed a systematic error. Taking this error into account, physiotherapists can use the Orthelligent Pro sensor as a valid and reliable instrument for measuring the jump height of countermovement jumps.


Assuntos
Perna (Membro) , Humanos , Masculino , Adulto , Feminino , Reprodutibilidade dos Testes , Perna (Membro)/fisiologia , Adulto Jovem , Atletas , Fenômenos Biomecânicos/fisiologia , Movimento/fisiologia
17.
PLoS One ; 19(6): e0304136, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38848389

RESUMO

INTRODUCTION: Single-leg cycling is a commonly used intervention in exercise physiology that has applications in exercise training and rehabilitation. The addition of a counterweight to the contralateral pedal helps single-leg cycling mimic cycling patterns of double-leg cycling. To date, no research has tested (a) the influence of a wide range of counterweight masses on a person's cycling biomechanics and (b) the optimal counterweight mass to emulate double-leg cycling. OBJECTIVES: The purpose of this study was to determine the effects of varying counterweights on the kinematics (joint angles) and kinetics (joint moments, work) of cycling using a 3D analysis. METHODS: Twelve participants cycled at 50W or 100W with different counterweight masses (0 to 30 lbs, 2.5 lbs increments), while we analyzed the pedal force data, joint angles, joint moments, and joint power of the lower limb using 3D motion capture and 3D instrumented pedals to create participant-specific musculoskeletal models. RESULTS: The results showed that no single-leg cycling condition truly emulated double-leg cycling with respect to all measured variables, namely pedal forces (p ≤ 0.05), joint angles (p ≤ 0.05), joint moments(p ≤ 0.05), and joint powers (p ≤ 0.05), but higher counterweights resulted in single-leg cycling that was statistically similar (p > 0.05), but descriptively, asymptotically approached the biomechanics of double-leg cycling. CONCLUSION: We suggest that a 20-lb counterweight is a conservative estimate of the counterweight required for using single-leg cycling in exercise physiology studies, but further modifications are needed to the cycle ergometer for the biomechanics of single-leg cycling to match those of double-leg cycling.


Assuntos
Ciclismo , Humanos , Fenômenos Biomecânicos , Ciclismo/fisiologia , Masculino , Adulto , Adulto Jovem , Feminino , Perna (Membro)/fisiologia
19.
Sci Rep ; 14(1): 12860, 2024 06 04.
Artigo em Inglês | MEDLINE | ID: mdl-38834832

RESUMO

A common theory of motor control posits that movement is controlled by muscle synergies. However, the behavior of these synergies during highly complex movements remains largely unexplored. Skateboarding is a hardly researched sport that requires rapid motor control to perform tricks. The objectives of this study were to investigate three key areas: (i) whether motor complexity differs between skateboard tricks, (ii) the inter-participant variability in synergies, and (iii) whether synergies are shared between different tricks. Electromyography data from eight muscles per leg were collected from seven experienced skateboarders performing three different tricks (Ollie, Kickflip, 360°-flip). Synergies were extracted using non-negative matrix factorization. The number of synergies (NoS) was determined using two criteria based on the total variance accounted for (tVAF > 90% and adding an additional synergy does not increase tVAF > 1%). In summary: (i) NoS and tVAF did not significantly differ between tricks, indicating similar motor complexity. (ii) High inter-participant variability exists across participants, potentially caused by the low number of constraints given to perform the tricks. (iii) Shared synergies were observed in every comparison of two tricks. Furthermore, each participant exhibited at least one synergy vector, which corresponds to the fundamental 'jumping' task, that was shared through all three tricks.


Assuntos
Eletromiografia , Movimento , Músculo Esquelético , Humanos , Músculo Esquelético/fisiologia , Masculino , Adulto , Movimento/fisiologia , Feminino , Adulto Jovem , Fenômenos Biomecânicos , Patinação/fisiologia , Perna (Membro)/fisiologia
20.
Sci Rep ; 14(1): 12916, 2024 06 05.
Artigo em Inglês | MEDLINE | ID: mdl-38839895

RESUMO

This study was designed to assess the optimal access route for the endovascular treatment of acute lower extremity deep vein thrombosis. This was a retrospective analysis of patients with acute lower extremity deep venous thrombosis who underwent endovascular treatment from February 2009 to December 2020. Patients underwent non-direct calf deep vein puncture (NDCDVP) from February 2009 to December 2011 and direct calf deep vein puncture (DCDVP) from January 2012 to December 2020. Catheter directed thrombolysis (CDT) was used to treat all patients in the NDCDVP group, whereas patients in the DCDVP group were treated with CDT or the AngioJet rhyolitic thrombectomy system. In patients exhibiting iliac vein compression syndrome, the iliac vein was dilated and implanted with a stent. Technical success rates and perioperative complication rates were compared between these two treatment groups. The NDCDVP group included 83 patients (40 males, 43 females) with a mean age of 55 ± 16 years, while the DCDVP group included 487 patients (231 males. 256 females) with a mean age of 56 ± 15 years. No significant differences were observed between these groups with respect to any analyzed clinical characteristics. The technical success rates in the NDCDVP and DCDVP groups were 96.4 and 98.2%, respectively (P > 0.05). In the NDCDVP group, the small saphenous vein (SSV)or great saphenous vein (GSV)were the most common access routes (77.1%, 64/83), whereas the anterior tibial vein (ATV) was the most common access route in the DCDVP group (78.0%, 380/487), followed by the posterior tibial vein (PTV) and peroneal vein (PV)(15.6% and 6.4%, respectively). Relative to the NDCDVP group, more patients in the DCDVP group underwent the removal of deep vein clots below the knee (7.2% [6/83] vs. 24.2% [118/487], P < 0.001). Moreover, relative to the NDCDVP group, significantly lower complication rates were evident in the DCDVP group (local infection: 10.8% vs. 0.4%, P < 0.001; local hematoma: 15.7% vs. 1.0%, P < 0.001). The position change rate was also significantly lower in the DCDVP group relative to the NDCDVP group (0% [0/487] vs. 60.2% [50/83], P < 0.001). The calf deep veins (CDVs) represent a feasible and safe access route for the endovascular treatment of lower extremity deep vein thrombosis.


Assuntos
Procedimentos Endovasculares , Extremidade Inferior , Trombose Venosa , Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Trombose Venosa/terapia , Estudos Retrospectivos , Procedimentos Endovasculares/métodos , Procedimentos Endovasculares/efeitos adversos , Idoso , Extremidade Inferior/irrigação sanguínea , Extremidade Inferior/cirurgia , Adulto , Trombectomia/métodos , Trombectomia/efeitos adversos , Resultado do Tratamento , Terapia Trombolítica/métodos , Perna (Membro)/irrigação sanguínea
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA