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1.
PLoS One ; 16(1): e0244532, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33411707

RESUMO

BACKGROUND: The first cases of coronavirus disease (COVID-19) in Brazil were diagnosed in February 2020. Our Emergency Department (ED) was designated as a COVID-19 exclusive service. We report our first 500 confirmed COVID-19 pneumonia patients. METHODS: From 14 March to 16 May 2020, we enrolled all patients admitted to our ED that had a diagnosis of COVID-19 pneumonia. Infection was confirmed via nasopharyngeal swabs or tracheal aspirate PCR. The outcomes included hospital discharge, invasive mechanical ventilation, and in-hospital death, among others. RESULTS: From 2219 patients received in the ED, we included 506 with confirmed COVID-19 pneumonia. We found that 333 patients were discharged home (65.9%), 153 died (30.2%), and 20 (3.9%) remained in the hospital. A total of 300 patients (59.3%) required ICU admission, and 227 (44.9%) needed invasive ventilation. The multivariate analysis found age, number of comorbidities, extension of ground glass opacities on chest CT and troponin with a direct relationship with all-cause mortality, whereas dysgeusia, use of angiotensin converting enzyme inhibitor or angiotensin-ii receptor blocker and number of lymphocytes with an inverse relationship with all-cause mortality. CONCLUSIONS: This was a sample of severe patients with COVID-19, with 59.2% admitted to the ICU and 41.5% requiring mechanical ventilator support. We were able to ascertain the outcome in majority (96%) of patients. While the overall mortality was 30.2%, mortality for intubated patients was 55.9%. Multivariate analysis agreed with data found in other studies although the use of angiotensin converting enzyme inhibitor or angiotensin-ii receptor blocker as a protective factor could be promising but would need further studies. TRIAL REGISTRATION: The study was registered in the Brazilian registry of clinical trials: RBR-5d4dj5.

2.
PLoS One ; 16(1): e0245051, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33411768

RESUMO

Public health policies to contain the spread of COVID-19 rely mainly on non-pharmacological measures. Those measures, especially social distancing, are a challenge for developing countries, such as Brazil. In São Paulo, the most populous state in Brazil (45 million inhabitants), most COVID-19 cases up to April 18th were reported in the Capital and metropolitan area. However, the inner municipalities, where 20 million people live, are also at risk. As governmental authorities discuss the loosening of measures for restricting population mobility, it is urgent to analyze the routes of dispersion of COVID-19 in São Paulo territory. We hypothesize that urban hierarchy is the main responsible for the disease spreading, and we identify the hotspots and the main routes of virus movement from the metropolis to the inner state. In this ecological study, we use geographic models of population mobility to check for patterns for the spread of SARS-CoV-2 infection. We identify two patterns based on surveillance data: one by contiguous diffusion from the capital metropolitan area, and the other hierarchical with long-distance spread through major highways that connects São Paulo city with cities of regional relevance. This knowledge can provide real-time responses to support public health strategies, optimizing the use of resources in order to minimize disease impact on population and economy.

5.
J Appl Gerontol ; : 733464820983976, 2021 Jan 06.
Artigo em Inglês | MEDLINE | ID: mdl-33406963

RESUMO

OBJECTIVE: Analyzing the survival of older people hospitalized due to COVID-19 in Brazil and identifying its main predictive factors for death. METHOD: This is a retrospective, multicenter cohort study, based on 20,831 records of hospitalizations of older people due to SARS-CoV-2 in Brazil. The observation period was from February 28 to May 18, 2020. RESULTS: There was a reduced overall survival time of 47.70% (95% confidence interval [CI] = [46.72%, 48.67%]) in 10 days. The variables age, race, education, intensive care unit (ICU), region, day of hospitalization, time elapsed between the first symptom and hospitalization, and the municipality that provided assistance showed increased risk of death using the multiple Cox proportional-hazards model. CONCLUSION: These results emphasize the relevance of inequality and access to health services as determinants for the death of older people with COVID-19.

6.
J Med Virol ; 2021 Jan 09.
Artigo em Inglês | MEDLINE | ID: mdl-33421163

RESUMO

We described the detection of SARS-CoV-2 in stool samples from patients presenting only acute gastroenteritis (AGE) symptoms. From January to July 2020, 121 AGE stool samples were screened by RT-qPCR. We detected SARS-CoV-2 in 27.5% of samples received during the epidemic period. No infectious viruses were observed in Vero E6 cells. This article is protected by copyright. All rights reserved.

7.
Preprint em Português | SciELO Preprints | ID: pps-1667

RESUMO

This study describes changes in body weight among participants of the NutriNet Brazil cohort (n=14,529) during the COVID-19 pandemic. Body weight data reported in the period before the start of the pandemic (26/01-18/03/2020) and about 6 months after (14/09-19/10/2020) were analyzed. Weight gain ≥2 kg reached 19.7% of the participants and was inversely associated with age and directly associated with lower education and baseline overweight status. Weight loss ≥2kg reached 15.2% of the participants and was inversely associated with age and directly associated with higher education and baseline overweight status.


Este estudo descreve modificações no peso corporal de participantes da coorte NutriNet Brasil (n=14.529) ocorridas durante a pandemia de COVID-19. Foram analisados dados de peso corporal informados em período anterior ao início da pandemia (26/01-18/03/2020) e cerca de 6 meses após (14/09-19/10/2020). Ganho de peso ≥2 kg alcançou 19,7% dos participantes e mostrou-se inversamente associado à idade e diretamente associado à menor escolaridade e à presença prévia de excesso de peso. Perda de peso ≥2kg alcançou 15,2% dos participantes e mostrou-se inversamente associada à idade e diretamente associada à maior escolaridade e à presença prévia de excesso de peso.

8.
Environ Dev Sustain ; : 1-19, 2021 Jan 03.
Artigo em Inglês | MEDLINE | ID: mdl-33424425

RESUMO

Abstract: The first case of COVID-19 in Brazil was registered in the city of São Paulo on February 26, 2020; however, restrictive measures and social distancing were only determined in the city on March 17, 2020. A partial lockdown aimed to mitigate the advance of the virus by raising the social isolation rates, by limiting the operation of several services and the mobility of the population. Thus, this study aims to analyze the relationship between the social isolation index in the city of São Paulo and the emission levels of the main air pollutants (PM10, PM2.5, NOx, NO, NO2, SO2 and CO), as well as air temperature. We analyzed the data collected from three urban air quality monitoring stations located in the city center of São Paulo from March 16, 2020 to July 20, 2020. The data for 2020 were compared with those of the previous period in 2020 and the same period in the previous 5 years (2015-2019), and also to the city's official indices of social isolation. The relationships between pollutant concentrations and the social isolation index showed that the decrease in mobility influenced the reduction in air pollution. Pollutants NO2, NOx, NO and CO had the strongest negative associations (Pearson's correlation = - 0.582; 0.481; - 0.433 and - 0.367, respectively). Our results showed that the partial lockdown (from March 17, 2020, to July 20, 2020) had a positive impact on air quality, with a reduction in the emission of pollutants NO (31.75%), NO2 (20.60%), NOx (27.21%) and CO (29.95%). The greatest reductions in the emission of pollutants were observed when the social isolation index reached an average of 52.20%. Small negative fluctuations in the social isolation index broke the most significant reductions observed at the beginning of social isolation.

9.
Work ; 2021 Jan 07.
Artigo em Inglês | MEDLINE | ID: mdl-33427724

RESUMO

BACKGROUND: Community Health Workers (CHW) are a category of social workers described in many countries' health systems as responsible for engaging people in their residences and communities, and other non-clinical spaces to enable access to health services, especially in low-income areas. These professionals have been exposed to numerous new risks during the COVID-19 pandemic. OBJECTIVE: This study describes how the COVID-19 pandemic is perceived by CHWs who work in poor communities or slums in Brazil. METHODS: We conducted an online survey with a random sample of 775 CHWs operating in 368 municipalities of the 26 Brazilian states. At a confidence level of 95% , results of the survey were subject to a maximum sampling error of 4% . RESULTS: Our data indicate that the negationist agenda increases the challenges to the performance of CHWs within low-income communities, preventing the consensus on the necessity of social distancing, business closures and other measures to face the COVID-19 pandemic. CONCLUSION: The pandemic imposes unexpected challenges on the usual modes of interaction of public health officers with poor communities. This study provides evidence that these challenges have been ignored or minimized in Brazilian policy prescriptions for primary care in the face of the COVID-19 pandemic.

10.
Trab. educ. saúde ; 19: e00305137, jan. 2021. tab
Artigo em Português | LILACS | ID: biblio-1139810

RESUMO

Resumo Nesta breve exposição, pretende-se discutir como a crise político-econômica conjugou-se, à perfeição, à pandemia, para construir soluções lucrativas aos grandes capitais. O texto apresenta, com base na análise de dados recentes, como o Estado brasileiro, no governo Bolsonaro, empenha-se em aprofundar o programa de ajuste, por meio de privatizações de estatais e de rebaixamento dos direitos e do valor da força de trabalho, como base de um programa político-econômico e fiscal. A Nota explora ainda a hipótese de que tal plataforma tem o potencial de assegurar o continuado apoio da grande burguesia ao governo de Bolsonaro e Guedes.


Abstract In this brief presentation, we intend to discuss how the political-economic crisis combined perfectly with the pandemic to build profitable solutions for big capitalists. Based on the analysis of recent data, the text shows how the Brazilian State, under the Bolsonaro government, is committed to deepening the adjustment program, through privatization of state enterprises and downgrading the workforce's rights and value, as the basis of a political-economic and fiscal program. The Note also explores the hypothesis that such a platform has the potential to ensure the continued support of the great bourgeoisie to the government of Bolsonaro and Guedes.


Resumen En esta breve exposición, se pretende discutir como la crisis político económica se conjugó, a la perfección, con la pandemia, para construir soluciones lucrativas para los grandes capitales. El texto, basado en el análisis de datos recientes, presenta como el Estado brasileño, en el gobierno Bolsonaro, se empeña en profundizar el programa de ajuste, por medio de la privatización de las estatales y rebajando los derechos y el valor de la fuerza de trabajo, como base de un programa político económico y fiscal. La Nota explora aun la hipótesis de que tal plataforma tiene el potencial de asegurar el continuado apoyo de la gran burguesía al gobierno de Bolsonaro y Guedes.


Assuntos
Humanos , Economia , Recursos Humanos , Pandemias
11.
Lancet ; 397(10269): 99-111, 2021 Jan 09.
Artigo em Inglês | MEDLINE | ID: mdl-33306989

RESUMO

BACKGROUND: A safe and efficacious vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), if deployed with high coverage, could contribute to the control of the COVID-19 pandemic. We evaluated the safety and efficacy of the ChAdOx1 nCoV-19 vaccine in a pooled interim analysis of four trials. METHODS: This analysis includes data from four ongoing blinded, randomised, controlled trials done across the UK, Brazil, and South Africa. Participants aged 18 years and older were randomly assigned (1:1) to ChAdOx1 nCoV-19 vaccine or control (meningococcal group A, C, W, and Y conjugate vaccine or saline). Participants in the ChAdOx1 nCoV-19 group received two doses containing 5 × 1010 viral particles (standard dose; SD/SD cohort); a subset in the UK trial received a half dose as their first dose (low dose) and a standard dose as their second dose (LD/SD cohort). The primary efficacy analysis included symptomatic COVID-19 in seronegative participants with a nucleic acid amplification test-positive swab more than 14 days after a second dose of vaccine. Participants were analysed according to treatment received, with data cutoff on Nov 4, 2020. Vaccine efficacy was calculated as 1 - relative risk derived from a robust Poisson regression model adjusted for age. Studies are registered at ISRCTN89951424 and ClinicalTrials.gov, NCT04324606, NCT04400838, and NCT04444674. FINDINGS: Between April 23 and Nov 4, 2020, 23 848 participants were enrolled and 11 636 participants (7548 in the UK, 4088 in Brazil) were included in the interim primary efficacy analysis. In participants who received two standard doses, vaccine efficacy was 62·1% (95% CI 41·0-75·7; 27 [0·6%] of 4440 in the ChAdOx1 nCoV-19 group vs71 [1·6%] of 4455 in the control group) and in participants who received a low dose followed by a standard dose, efficacy was 90·0% (67·4-97·0; three [0·2%] of 1367 vs 30 [2·2%] of 1374; pinteraction=0·010). Overall vaccine efficacy across both groups was 70·4% (95·8% CI 54·8-80·6; 30 [0·5%] of 5807 vs 101 [1·7%] of 5829). From 21 days after the first dose, there were ten cases hospitalised for COVID-19, all in the control arm; two were classified as severe COVID-19, including one death. There were 74 341 person-months of safety follow-up (median 3·4 months, IQR 1·3-4·8): 175 severe adverse events occurred in 168 participants, 84 events in the ChAdOx1 nCoV-19 group and 91 in the control group. Three events were classified as possibly related to a vaccine: one in the ChAdOx1 nCoV-19 group, one in the control group, and one in a participant who remains masked to group allocation. INTERPRETATION: ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials. FUNDING: UK Research and Innovation, National Institutes for Health Research (NIHR), Coalition for Epidemic Preparedness Innovations, Bill & Melinda Gates Foundation, Lemann Foundation, Rede D'Or, Brava and Telles Foundation, NIHR Oxford Biomedical Research Centre, Thames Valley and South Midland's NIHR Clinical Research Network, and AstraZeneca.

12.
Int J Health Serv ; 51(1): 18-30, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33070682

RESUMO

This article aims to discuss the meaning of the coronavirus crisis as an integral part of the totality of the capitalist crisis and its implication in the health area of Brazilian capitalism, in which the rise of ultraliberal and neofascist policies is witnessed by the Bolsonaro government. To this end, we opted for a historical-dialectical materialist analysis of the situation experienced between the global beginning of the pandemic until the month of May 2020 in Brazil. The article is structured in 2 parts: The first discusses the problem of agrifood systems in the context of capitalism in crisis and its effects on the spread of diseases such as the coronavirus, and the second discusses the neglect of the Bolsonaro government in facing the COVID-19 pandemic and the Brazilian universal health system. Evidence shows that the Bolsonaro government has led to more deaths and more of the barbarism of capitalism. The scenario after the pandemic will be one of a country with a more or less intense capitalist crisis depending on the resistance of workers in the defense of public health and lives.


Assuntos
/epidemiologia , Capitalismo , Assistência à Saúde/economia , Brasil/epidemiologia , Política de Saúde , Humanos , Pandemias , Política , Saúde Pública
13.
Health Educ Behav ; 48(1): 29-33, 2021 02.
Artigo em Inglês | MEDLINE | ID: mdl-33322924

RESUMO

Decreased engagement in preventive services, including vaccination, during the COVID-19 pandemic represents a grave threat to global health. We use the case of the Bom Retiro Public Health Clinic in São Paulo, Brazil, to underscore how continuity of care is not only feasible, but a crucial part of health as a human right. The long-standing relationship between the clinic and neighborhood residents has facilitated ongoing management of physical and mental health conditions. Furthermore, we demonstrate how the clinic's history of confronting infectious diseases has equipped it to adapt preventive services to meet patients' needs during the pandemic. Our academic-community partnership used a multidisciplinary approach, relying on analysis of historical data, ethnographic data, and direct clinical experience. We identify specific prevention strategies alongside areas for improvement. We conclude that the clinic serves as a model for continuity of care in urban settings during a pandemic.

14.
Int J Paediatr Dent ; 31(1): 12-19, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32978848

RESUMO

BACKGROUND: During COVID-19 pandemic, children are confined at home, with changes in family routines. AIM: Evaluate sleep disorders among Brazilian and Portuguese children during social distancing, and its association with parental perception of child's oral hygiene. DESIGN: In this cross-sectional study, Portuguese and Brazilian parents/caregivers of 3- to 15-year-old children, practicing social distancing due to COVID-19 pandemic, answered an online questionnaire, from April 24-26, 2020, evaluating sociodemographic characteristics, child's school activities online, child's sleep quality during social distancing. Two questions from the questionnaire, developed based on previous studies, evaluated the parental perception of child's oral hygiene quality and routine changes during social distancing. Parents/caregivers answered five domains of the Portuguese-language version of the Sleep Disturbances Scale for Children, evaluating sleep-breathing disorders, disorders of arousal, sleep-wake transition disorders, disorders of excessive somnolence and sleep hyperhidrosis. Descriptive, Linear-by-linear association, Kruskal-Wallis and post hoc analysis were performed (P ≤ .05). RESULTS: Participated in the study 253 parents/caregivers, 50.2% from Brazil. Most parents (72.2%) reported changes in child's routine during social distancing. Sleep breathing disorders (P = .019), sleep-wake transition disorders (P = .022), and disorders of excessive somnolence (P < .001) were associated with poor oral hygiene during social distancing. CONCLUSION: Sleep disorders are associated with poor oral hygiene during social distancing.


Assuntos
Pandemias , Adolescente , Brasil/epidemiologia , Criança , Pré-Escolar , Estudos Transversais , Humanos , Higiene Bucal , Pais , Sono , Inquéritos e Questionários
15.
Int Braz J Urol ; 47(2): 378-385, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33146983

RESUMO

INTRODUCTION: The rapid spread of coronavirus disease 2019 (COVID-19) has dramatic effects on individuals and health care systems. In our institute, a tertiary oncologic public hospital with high surgical volume, we prioritize maintaining cancer treatment as well as possible. The aim of this study is to evaluate if uro-oncological surgeries at pandemic are safe. MATERIALS AND METHODS: We evaluated patients who underwent uro-oncological procedures. Epidemiological data, information on COVID-19 infection related to surgery and clinical characteristics of non-survival operative patients with COVID-19 infections were analyzed. RESULTS: From 213 patients analyzed, Covid-19 symptoms were noticed in 8 patients at preoperative process or at hospital admission postponing operation; 161 patients were submitted to elective surgery and 44 to emergency surgery. From patients submitted to elective surgeries, we had 1 patient with laboratory confirmation of COVID-19 (0,6%), with mild symptoms and quick discharge. From the urgencies group, we had 6(13%)patients tested positive; 5 were taken to ICU with 4 deaths. CONCLUSION: Elective uro-oncological procedures at the COVID-19 epidemic period in a COVID-19-free Institute are safe, and patients who need urgent procedures, with a long period of hospitalization, need special care to avoid COVID-19 infection and its outcomes.


Assuntos
Pandemias , Oncologia Cirúrgica/estatística & dados numéricos , Urologia/estatística & dados numéricos , Brasil/epidemiologia , Humanos
16.
Sci Total Environ ; 755(Pt 1): 142471, 2021 Feb 10.
Artigo em Inglês | MEDLINE | ID: mdl-33010498

RESUMO

The World Health Organization has recently declared South America the new epicenter of the COVID-19 pandemic, as Brazil has become one of the most affected countries. Besides public health and economic impacts, social isolation has also caused indirect environmental effects. The aim of this study was to assess environmental impacts caused by shifts on solid waste production and management due to the COVID-19 pandemic in Brazil. We have analyzed data from 30 cities, representing a population of more than 53.8 million people (25.4% of the Brazilian population). Unexpectedly, solid waste production in the main cities in Brazil has decreased during the social isolation period, possibly because of reduced activity in commercial areas. The latest data on solid waste in Brazil have revealed that more than 35% of medical waste has not been treated properly. Furthermore, improper disposal of facemasks has been reported in several cities and may increase the risk for COVID-19 spread. The suspension of recycling programs has hindered natural resources from being saved, with emphasis on 24,076 MWh of electric power and 185,929 m3 of potable water - respectively enough to supply 152,475 households and 40,010 people, over a month. Furthermore, total sale price for recyclable materials during the suspension of recycling programs reaches more than 781 thousand dollars, being these materials disposed in landfills - demanding an extra volume of 19,000 m3 - reducing landfill lifespan, and hence causing a double loss: economic and environmental.


Assuntos
Eliminação de Resíduos , Gerenciamento de Resíduos , Brasil/epidemiologia , Cidades , Meio Ambiente , Humanos , Pandemias , Resíduos Sólidos/análise , Instalações de Eliminação de Resíduos
17.
Ann Anat ; 233: 151608, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-33022405

RESUMO

COVID-19 is an infection caused by the SARS-CoV-2 virus, initially identified in the city of Wuhan, China, in December 2019. Since then, the virus has spread to the continents, causing a major pandemic. The impacts of this pandemic on the education of human anatomy interfere in at least two aspects: (1) receiving and managing anatomical specimens in anatomy laboratories and (2) adaptations for classes on remote virtual teaching. Therefore, this study reviewed and discussed the legal and bioethical aspects, considering the scenario of a South American Country, aiming to stimulate the debate on these two relevant themes in the international community. Because of the COVID-19 pandemic and the impossibility of mass testing, anatomists and other workers in the field must deal with the risk of receiving bodies infected with SARS-CoV-2. In this situation, additional care measures in biosafety practices are essential to protect the staff. Such measures are: the bodies must be preserved by the perfusion of formaldehyde or other fixative solutions; embalming must be performed in ventilated rooms with a good air exhaust system; to avoid excessive manipulation of bodies and procedures such as pulmonary insufflation or craniotomy; and proper use of personal protective equipment, including lab coat, gloves and masks. As for exposure of body images in online classes, this review showed that there are no legal impediments to this end. However, anatomists must adopt measures aimed at protecting the memory of the deceased, such as using secure digital platforms with restricted access; family authorization/consent and student awareness.


Assuntos
Anatomia/educação , Pandemias , Manejo de Espécimes/ética , Brasil , Contenção de Riscos Biológicos , Embalsamamento , Pessoal de Saúde , Humanos , Legislação Médica , Segurança , Ventilação
18.
J Psychiatr Res ; 132: 32-37, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33038563

RESUMO

Public health interventions at general population level are imperative in order to decrease the spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but they may contribute to widespread emotional distress and increased risk for psychiatric illnesses. We report on the results of an investigation into the occurrence and determinants of psychiatric symptoms among the Brazilian general population (N = 1996). We assessed sociodemographic variables and general mental health (DSM-5 Self-Rated Level 1 Cross-Cutting Symptom Measure), depression (PROMIS depression v.8a), anxiety (PROMIS anxiety v.8a), and post-traumatic stress symptoms (Impact of Event Scale-IES-R scale) using an online web-based survey. Anxiety (81.9%), depression (68%), anger (64.5%), somatic symptoms (62.6%) and sleep problems (55.3%) were the most common psychiatric symptoms. Younger age, female gender, low income, lower level of education, longer period of social distancing, and self-reported history of previous psychiatric illness were strongly associated with higher severity of symptoms. Our results support the negative impact of the COVID-19 pandemic on the mental health of the Brazilian population. The high prevalence of psychiatric symptoms observed in our sample indicates that the mental health impact of the COVID-19 pandemic should be considered a public health problem in Brazil. The health systems and individual clinicians must be prepared to offer and implement specific interventions in order to identify and treat psychiatric issues.


Assuntos
Sintomas Comportamentais/epidemiologia , Transtornos do Sono-Vigília/epidemiologia , Transtornos de Estresse Pós-Traumáticos/epidemiologia , Adulto , Ansiedade/epidemiologia , Brasil/epidemiologia , Estudos Transversais , Depressão/epidemiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Fatores Socioeconômicos , Adulto Jovem
20.
Trop Med Int Health ; 26(1): 115-119, 2021 01.
Artigo em Inglês | MEDLINE | ID: mdl-33217116

RESUMO

OBJECTIVE: To describe COVID-19 deaths among children and adolescents in Sergipe, Brazil. METHODS: Ecological study of all COVID-19 reported cases and deaths occurring in children and adolescents < 19 years of age in Sergipe reported by the health surveillance and mortality information systems of Sergipe's Health Secretary and hospital records. RESULTS: Of 37 deaths of children < 19 years old were reported up to 30 September 2020, corresponding to 4.87 deaths for 100 000 population < 19 years old. Most deaths occurred among infants (44.1/100 000), and this age group had the highest case fatality rate (15.3 %). Most children had comorbidities such as chronic neurological diseases (n = 7; 19%) and prematurity (n = 4; 11%). Most children who died (n = 18; 49%) were not admitted to intensive care units (ICUs). CONCLUSION: COVID-19 mortality in children and adolescents in Sergipe was higher than in other Brazilian states and in high-income countries. A large proportion of the deaths occurred among children with comorbidities and a minority of children were admitted to ICU, reflecting the limited provision of such beds in the State. Newborns and infants are a high-risk group that must have priority in health public policy.


Assuntos
/mortalidade , Adolescente , Distribuição por Idade , Brasil/epidemiologia , Criança , Pré-Escolar , Comorbidade , Feminino , Hospitalização/estatística & dados numéricos , Humanos , Lactente , Recém-Nascido , Unidades de Terapia Intensiva , Masculino
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