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1.
Metas enferm ; 27(1): 28-34, Febr. 2024.
Artigo em Espanhol | IBECS | ID: ibc-230207

RESUMO

Objetivo: determinar la calidad de vida laboral en tiempos de COVID-19 del personal de Enfermería del Hospital Regional de Coronel Oviedo (Paraguay) durante el año 2022. Método: se realizó un estudio descriptivo trasversal en el Hospital Regional de Coronel Oviedo, en Paraguay, en enfermeros y enfermeras con al menos un año de experiencia. Se utilizó el cuestionario de calidad de vida laboral adaptado de Cruz Luque, además de variables sociodemográficas y laborales. Para los análisis bivariados entre las dimensiones del cuestionario de calidad de vida con las variables sociodemográficas y laborales, se utilizó la prueba de Chi cuadrado de Pearson. Resultados: se incluyeron 170 profesionales, con un rango etario entre 24 y 43 años, con predominio del sexo femenino (84,7%), estado civil casado (50,5%), con alguna especialización en el área (48,2%), y trabajando principalmente en un solo lugar. El promedio de pacientes diarios fue de uno a cinco pacientes (54,7%), con turnos laborales de 12 horas (56,4%). La percepción global de la calidad de vida laboral se ubicó entre mala (48%) y regular (37%). Las dimensiones específicas mostraron que la percepción más baja se encontró en el soporte institucional (48,82%) e integración en el puesto de trabajo (52,35%). Se identificaron asociaciones estadísticamente significativas entre la percepción de la calidad laboral y datos demográficos y laborales como edad, género, nivel educativo, turno de trabajo, experiencia laboral, horas trabajadas semanalmente y número de empleos. Conclusión: la percepción de calidad laboral se encontró entre mala y regular, siendo las dimensiones de soporte institucional y seguridad laboral las principales áreas críticas.(AU)


Objective: to determine the occupational quality of life in times of COVID-19 of the Nursing Staff of the Hospital Regional de Coronel Oviedo (Paraguay) during 2022. Method: a cross-sectional descriptive study was conducted at the Hospital Regional de Coronel Oviedo, in Paraguay, including male and female nurses with at least one year of experience. The adapted Occupational Quality of Life Questionnaire by Cruz Luque was used, as well as sociodemographic and occupational variables. Pearson’s Square Chi Test was used for bivariate analysis between the quality of life questionnaire dimensions and the sociodemographic and occupational variables. Results: the study included 170 professionals, with a 24-to-43-year age range, with prevalence of female gender (84.7%), married civil status (50.5%), with some specialization in the area (48.2%), and mostly working in one single place. The average daily patients were from one to five (54.7%), with 12-hour work shifts (56.4%). The overall perception of their occupational quality of life was between bad (48%) and moderate (37%). Specific dimensions showed that the lowest perception was found in institutional support (48.82%) and integration in the workplace (52.35%). Statistically significant associations were identified between the perception of work quality and demographic and occupational data such as age, gender, educational level, work shift, work experience, hours worked per week and number of jobs. Conclusion: the perception of quality of work was between bad and moderate, and the main critical areas were the dimensions of institutional support and safety at work.(AU)


Assuntos
Humanos , Masculino , Feminino , Qualidade de Vida , Enfermeiras e Enfermeiros , Paraguai
2.
BMC Infect Dis ; 24(1): 37, 2024 Jan 02.
Artigo em Inglês | MEDLINE | ID: mdl-38166777

RESUMO

BACKGROUND: The health crisis due to Covid-19 led to the search for therapeutics that could improve the evolution of the disease. Remdesivir, an antiviral that interferes with viral replication, was one of the first to be used for the treatment of this pathology. OBJECTIVE: To determine clinical course and mortality of patients with severe SARS-CoV-2 pneumonia treated with remdesivir, in comparison of those who didn't receive the medication. PATIENTS AND METHODS: Retrospective cohort study, with medical records review of COVID-19 patients, between August 2020 and August 2021. The subjects were divided into two groups, those who received remdesivir before or after admission to intensive care and those who didn't. The primary outcome variable was mortality in intensive care. RESULTS: Of 214 subjects included, 109 (50,9%) received remdesivir. The median of days for the drug administration was 8 (2-20), IQR: 3. The bivariate analysis prove that the use of remdesivir was related with lower risk of develop Acute Respiratory Distress Syndrome (ARDS) (p = 0,019; OR: 0,521) and lower requirement of mechanical ventilation (p = 0,006; OR:0,450). Additionally, patients treated with remdesivir develop less kidney injury (p = 0,009; OR: 0,441). There was a total of 82 deaths, 29 (26,6%) in the remdesivir group and 53 (50,5%) in the control group [p < 0,001; OR: 0,356 (0,201-0,630)]. All the risk factors associated with mortality in the bivariate analysis were entered into the multivariate analysis by logistic regression, the use of remdesivir remained associated as an independent protective factor to mortality (p = 0.034; OR: 0.429). CONCLUSION: Critically ill patients with SARS-CoV-2 pneumonia treated with remdesivir had a lower risk of death and need for mechanical ventilation and develop less ARDS as compared to the control group. No differences were found in the presentation of adverse effects.


Assuntos
COVID-19 , Síndrome do Desconforto Respiratório , Adulto , Humanos , SARS-CoV-2 , Estado Terminal , Paraguai , Estudos Retrospectivos , Resultado do Tratamento , Tratamento Farmacológico da COVID-19 , Unidades de Terapia Intensiva , Síndrome do Desconforto Respiratório/tratamento farmacológico , Antivirais/uso terapêutico
3.
Rev. cient. cienc. salud ; 6: 1-7, 30-01-2024.
Artigo em Inglês | LILACS, BDNPAR | ID: biblio-1526922

RESUMO

Introduction. The connection between news sources and the connotation of mental health articles in Paraguay during the COVID-19 pandemic (2020-2023) significantly impacted public opinion about mental health. Objective.This study analyzednews onmental health in Paraguay in the context of the COVID-19 pandemic. Material and methods.A descriptive retrospective study of all news articles on mental health published in the three primary newspapers of the country between May 2020 and May 2023 was conducted. The keywords were depressive disorders, anxiety disorders, bipolar disorder, schizophrenia, and mental health issues. Results. A total of 534 newswereexamined, 39.5% published by La Nación newspaper, 33.1% in 2023, and in 88.4% the author's identity and gender were not specified. Of the writing characteristics, 99.8% were written in the third person, 62.7% had a human-interest context,48.5% had a neutral connotation, 65.7% focused on health and well-being,and 7.5% written by health experts. The year of publication wasstatistically associated to connotation (p=0.003) and context (p<0.001). Conclusion. The media has paid significant attention to mental health. Despite the objectivity provided by third-person narration, problems arise because of a lack of author identification. To encourage balanced and non-polarized reporting, it is crucial to incorporate expert voices and promote the framing of mental health stories as "human interest". Palabras clave: mental health; news; newspaper article; COVID-19; Paraguay


Introducción. La conexión entre las fuentes de noticias y la connotación de los artículos sobre salud mental en Paraguay durante la pandemia de COVID-19 (2020-2023) impactó significativamente en la opinión pública sobre la salud mental. Objetivo. Analizar las noticias sobre salud mental en Paraguay en el contexto de la pandemia COVID-19. Material y métodos. Se realizó un estudio descriptivo retrospectivo de todos los artículos periodísticos sobre salud mental publicados en los tres principales periódicos del país entre mayo de 2020 y mayo de 2023. Las palabras clave fueron trastornos depresivos, trastornos de ansiedad, trastorno bipolar, esquizofrenia y problemas de salud mental. Resultados. Se examinaron 534 artículos periodísticos, 39,5% publicados por el diario La Nación, 33,1% en 2023y en 88,4%no se especificó la identidad ni el género del autor. De las características de redacción, el 99,8% estaban escritos en tercera persona, 62,7% pertenecían a un contexto de interés humano,48,5% tenían una connotación neutra, 65,7% se centraban en la salud y el bienestar y el 7,5% escritos por expertos en salud. El año de publicación se asoció significativamente con la connotación (p=0,003) y con el contexto (p<0,001). Conclusión. Los medios de comunicación han prestado gran atención a la salud mental. A pesar de la objetividad que aporta la narración en tercera persona, surgen problemas por la falta de identificación del autor. Para fomentar una información equilibrada y no polarizada, es crucial incorporar voces expertas y promover el encuadre de las historias de salud mental como "interés humano". Key words: salud mental; noticias; artículo de periódico; COVID-19;Paraguay


Assuntos
Humanos , Masculino , Feminino , Saúde Mental , COVID-19 , Paraguai , Notícias , Artigo de Jornal
4.
Int J Soc Psychiatry ; : 207640231216342, 2023 Dec 07.
Artigo em Inglês | MEDLINE | ID: mdl-38059364

RESUMO

BACKGROUND: Positive mental health includes not only the absence of mental disorders but also the presence of subjective well-being, good coping strategies for life stress, and strategies for adapting to community life. It is well known that the COVID-19 pandemic has challenged mental health in general population worldwide. However, research has not measured protective factors for mental health in the general population after the declared end of pandemic by the World Health Organization. METHODS: This observational, cross-sectional study surveyed 591 Paraguayan participants aged ⩾18 years, who were recruited through an online survey. Demographic characteristics, socioeconomic status were collected as well as mental health and validated tools for hope, resilience, subjective happiness were administered. RESULTS: Of the participants, 81.6% were women, 54% were married or in a relationship and 90.7% reported an university education. The main source of stress was economic issues (30.3%). A total of 22.7% had been previously diagnosed with a mental disorder, 22.2% had consulted a mental health professional and 10.8% had consumed prescription drugs. 42.6% reported flourishing, 36.2% reported moderate and 21.2% reported languishing mental health. CONCLUSIONS: This large survey has shown that most of participants reported a flourishing mental health with high ratings at hope, resilience, and subjective happiness scales. Also, the main sources of stress were economic issues, not consequently related to the pandemic. This may add evidences to the international debate on the long term effects of the global pandemic and probably suggests that recovery processes have been collectively adopted in Paraguay.

5.
Med. clín. soc ; 7(3)dic. 2023.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1528990

RESUMO

Introducción: La transmisión viral a menudo se propaga en grupos, donde las infecciones se pueden rastrear hasta un caso índice o una ubicación geográfica, para así poder tomar medidas de prevención al respecto. Entender el perfil de transmisión del SARS-CoV-2 es esencial para desarrollar estrategias efectivas de prevención y control de la enfermedad. Objetivo: Determinar el perfil de transmisión del Sars-Cov-2, a partir de clúster con casos índices identificados, en la V región sanitaria (Caaguazu) del Paraguay, entre julio y octubre del 2020. Metodología: Se realizó un estudio observacional, descriptivo, de corte transversal, con fichas de notificación de casos de COVID-19 y resultados laboratoriales de la RT_PCR en pacientes diagnosticados con COVID-19 en la V Región Sanitaria entrejulio y octubre del 2020. Resultados: Fueron identificadas 703 personas con Sars-Cov-2 positivo. El 55,49 % de las personas no reconoció algún nexo de contagio. Con respecto al tipo de evento donde ocurrían con mayor frecuencia los contagios, ocurrieron en Eventos Sociales en 58,14 % de los casos y en el Ambiente Familiar en el 33,89 %. La transmisión secundaria se observó en el 17,40 % de los casos. Fueron identificados 58 Clústers, con una mediana de tamaño de los mismos de 3 (RIQ 2-4), y 267 personas (37,98 %) asociadas a los mismos. Discusión: La mayoría de las personas no reconocieron su nexo de contagio, sin embargo, en los que, si conocieron, se puede observar que la participación en eventos sociales fue el principal nexo, por lo que es fundamental realizar este tipo de ejercicios para hacer el seguimiento oportuno de los casos.


Introduction: Viral transmission often spreads in clusters, where infections can be traced to an index case or a geographic location, in order to take preventive measures in this regard, understanding the transmission profile of SARS-CoV-2 is essential. to develop effective disease prevention and control strategies. Objective: to determine the transmission profile of Sars-Cov-2, from clusters with identified index cases, in the V health region (Caaguazú) of Paraguay, between July and October 2020. Methodology: We carried out an observational, descriptive, cross-sectional study, with notification sheets of COVID-19 cases and laboratory results of the RT_PCR in patients diagnosed with COVID-19 in the V Sanitary Region between July and October 2020. Results: We identified 703 people with positive Sars-Cov-2. 55.49% of people did not recognize any contagion link. Regarding the type of event where infections occurred most frequently, was in Social Events in 58.14% of the cases and the Family Environment in 33.89%, secondary transmission was observed in 17.40% of the cases. 58 Clusters were identified, with a median size of 3 (IQR 2-4), and 267 people (37.98%) associated with them. Discussion: Most of the people did not recognize their contagion link, however, in those who did know, the main link was because they participated in social events, so it is essential to carry out this type of exercise to do timely follow-up. of the cases.

6.
J Infect Dev Ctries ; 17(10): 1407-1412, 2023 10 31.
Artigo em Inglês | MEDLINE | ID: mdl-37956377

RESUMO

INTRODUCTION: Severe Acute Respiratory Syndrome-Coronavirus-2 Virus (SARS-CoV-2) is responsible for Coronavirus Disease 2019 (COVID-19). A substantial number of SARS-CoV-2 infection cases have been reported during the pandemic, and vaccination coverage in some regions, particularly in developing countries, remains very low. SARS-CoV-2 variants of concern (VOCs) have also emerged as some of the most pressing public health issues. In this scenario, it is crucial to know whether COVID-19 convalescent antibodies have cross-neutralizing action against VOCs to contribute to the analysis of the future progress of the pandemic. METHODOLOGY: The plasma of individuals infected with SARS-CoV-2 from June to November 2020 in Paraguay (before the first recorded infections associated with VOCs in the country) was selected. Anti-spike antibodies were determined in plasma samples (n = 626) obtained from this convalescent and unvaccinated group. Using a pseudotyped virus neutralization assay, we then investigated the neutralizing response against D614G variant and Gamma, and Delta VOCs. RESULTS: IgG antibodies against spike were detected in 85.6% of convalescent individuals. Samples from individuals previously infected by a non-VOC showed a 6.6- and 8.1-fold reduction in neutralizing capacity to the Gamma and Delta variants, respectively, when compared to the D614G variant. CONCLUSIONS: Our findings show that antibodies generated by non-VOC infection have reduced neutralizing capabilities against Gamma and Delta variants that appeared subsequently and might have implications for immunity strategies.


Assuntos
Anticorpos Neutralizantes , COVID-19 , Humanos , SARS-CoV-2 , Paraguai/epidemiologia , Anticorpos Antivirais
7.
Vaccine ; 41(43): 6453-6460, 2023 Oct 13.
Artigo em Inglês | MEDLINE | ID: mdl-37716830

RESUMO

BACKGROUND: Vaccine effectiveness (VE) estimates vary by population characteristics and circulating variants. North America and Europe have generated many COVID-19 VE estimates but relied heavily on mRNA vaccines. Fewer estimates are available for non-mRNA vaccines and from Latin America. We aimed to estimate the effectiveness of several COVID-19 vaccines in preventing SARS-CoV-2-associated severe acute respiratory infection (SARI) in Paraguay from May 2021 to April 2022. METHODS: Using sentinel surveillance data from four hospitals in Paraguay, we conducted a test-negative case-control study to estimate COVID-19 vaccine effectiveness against SARI by vaccine type/brand and period of SARS-CoV-2 variant predominance (Gamma, Delta, Omicron). We used multivariable logistic regression adjusting for month of symptom onset, age group, and presence of ≥1 comorbidity to estimate the odds of COVID-19 vaccination in SARS-CoV-2 test-positive SARI case-patients compared to SARS-CoV-2 test-negative SARI control-patients. RESULTS: Of 4,229 SARI patients, 2,381 (56%) were SARS-CoV-2-positive case-patients and 1,848 (44%) were SARS-CoV-2-negative control-patients. A greater proportion of case-patients (73%; 95% CI: 71-75) than of control-patients (40%; 95% CI: 38-42) were unvaccinated. During the Gamma variant-predominant period, VE estimates for partial vaccination with mRNA vaccines and Oxford/AstraZeneca Vaxzevria were 90.4% (95% CI: 66.4-97.6) and 52.2% (95% CI: 25.0-69.0), respectively. During the Delta variant-predominant period, VE estimates for complete vaccination with mRNA vaccines, Oxford/AstraZeneca Vaxzevria, or Gamaleya Sputnik V were 90.4% (95% CI: 74.3-97.3), 83.2% (95% CI: 67.8-91.9), and 82.9% (95% CI: 53.0-95.2), respectively. The effectiveness of all vaccines declined substantially during the Omicron variant-predominant period. CONCLUSIONS: This study contributes to our understanding of COVID-19 VE in Latin America and to global understanding of vaccines that have not been widely used in North America and Europe. VE estimates from Paraguay can parameterize models to estimate the impact of the national COVID-19 vaccination campaign in Paraguay and similar settings.

8.
Med. clín. soc ; 7(2)ago. 2023.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1440498

RESUMO

Introducción: Durante la pandemia por COVID-19, factores como cierre de fronteras, recepción tardía de vacunas, limitación de circulación de la población, reubicación de enfermeros/as de áreas de vacunación a áreas de atención de pacientes con COVID-19, sumado el miedo al contagio, afectaron las coberturas de vacunación en varios países. Objetivo: Describir la percepción sobre la vacuna COVID-19 y su efecto en la cobertura de vacunación regular de pueblos indígenas del departamento de Presidente Hayes, Paraguay. 2022. Metodología: Estudio observacional descriptivo, retrospectivo de diseño cuali-cuantitativo de corte transversal. Resultados: Las características de los pueblos indígenas revela que 110(26,44 %) se ubica entre 28 a 37 años, 276(66,35 %) del sexo femenino, 133(31,97 %) son de la etnia Angaité, 290(69,71 %) poseen estudios hasta el nivel primario y 178(42,79 %) de estado civil soltero. La percepción hacia la vacunación COVID-19 fue favorable en 201 sujetos (48 %) y muy desfavorable en 148 (36 %). Existen pueblos indígenas con gran influencia de creencias culturales y religiosas en relación con las vacunas. La vacunación regular se vio afectada. Discusión: Se observó que la pandemia del COVID-19 y la aparición de la vacuna desarrolló desconfianza no solo en la vacuna COVID-19 si no también en el resto de las vacunas en algunos de los pueblos estudiados.


Introduction: During the COVID-19 pandemic, factors such as border closures, late receipt of vaccines, limitation of population circulation, relocation of nurses from vaccination areas to areas of care for patients with COVID-19, added to the fear of contagion affected vaccination coverage in several countries. Objective: Describe the perception of the COVID-19 vaccine and its effect on the regular vaccination coverage of indigenous peoples in the department of Presidente Hayes, Paraguay 2022. Methods: Descriptive, retrospective, observational study with a qualitative-quantitative cross-sectional design. Results: The characteristics of the indigenous peoples reveals that 110 (26.44%) are between 28 and 37 years old, 276 (66.35%) are female, 133 (31.97%) are of the Angaité ethnic group, 290 (69.71%) have studies up to the primary level and 178 (42.79%) have single marital status. The perception towards the COVID-19 vaccination was favorable in 201 subjects (48%) and very unfavorable in 148 (36%). There are indigenous peoples with great influence of cultural and religious beliefs in relation to vaccines. Regular vaccination was affected. Discussion: It was observed that the COVID-19 pandemic and the appearance of the vaccine developed distrust not only in the COVID-19 vaccine but also in the rest of the vaccines in some of the towns studied.

9.
Rev. chil. infectol ; 40(3)jun. 2023.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1515132

RESUMO

Introducción: La pandemia por COVID-19 es un problema de salud mundial. Habitualmente cursa con sintomatología leve y 5% de los afectados evoluciona a cuadros graves que requieren de cuidados intensivos. Objetivo: Determinar el perfil clínico, la mortalidad y factores asociados a la misma en pacientes con COVID-19 ingresados al Departamento de Cuidados Intensivos de Adultos, del Hospital de Clínicas de la Facultad de Ciencias Médicas, Universidad Nacional de Asunción, Paraguay, entre agosto de 2020 a agosto de 2021. Pacientes y Método: Se realizó un estudio observacional analítico de corte transverso. Los datos se obtuvieron a partir de las historias clínicas de los pacientes. Resultados: Se incluyeron 214 pacientes críticos entre 21 y 85 años de edad (mediana 54 años), 57,9% del sexo masculino, 85% provenientes del Departamento Central y Asunción. La mortalidad global fue de 38,3%. Se asociaron significativamente con la mortalidad una edad ≥ 60 años, las comorbilidades (diabetes mellitus, cardiopatía, enfermedad renal crónica), los índices de gravedad (APACHE II, SOFA, inicial), procalcitonina elevada, utilización de vasopresor, asistencia respiratoria mecánica y utilización del decúbito prono; así como la presencia de SDRA y el requerimiento de depuración extrarenal. En el análisis multivariado (por regresión logística) los factores de riesgo de mortalidad independientes fueron: la edad mayor de 60 años, la utilización de noradrenalina y depuración extra-renal durante la hospitalización. Conclusión: Nuestra mortalidad es similar a la reportada internacionalmente. Los factores de riesgo de mortalidad identificados muestran una población con mayores posibilidades de un desenlace desfavorable.


Background: The COVID-19 pandemic is a world health issue. Generally, it is with mild and around 5% evolves to a severe disease that requires intensive care. Aim: To determine the clinical profile, mortality and associated factors in COVID-19 patients admitted at the Adult Intensive Care Department at the Hospital de Clinicas, between August 2020 and August 2021. Methods: Cross-section observational analytic study. Data was obtained from clinical charts. Results: 214 patients were included, with an average age of 54 years, 57.9% male. Overall mortality was 38.3%. Factors associated significantly with mortality were: ≥60 years of age, comorbidity (diabetes mellitus, heart disease, chronic renal disease), severity index (APACHE II, initial SOFA), high procalcitonin, use of vasopressor, mechanical respiratory assistance and prone decubitus; as well as the presence of acute respiratory distress syndrome and hemodialysis. Multi varied analysis identified as mortality risk factors: ≥60 years of age, noradrenaline use and hemodialysis. Conclusion: Mortality rate is similar to that reported worldwide. Mortality risk factors identified show a population with higher possibilities for unfavorable outcome.

10.
Viruses ; 15(5)2023 05 10.
Artigo em Inglês | MEDLINE | ID: mdl-37243222

RESUMO

Soon after the declaration of the COVID-19 pandemic, the Institute for Health Sciences Research (IICS) of the National University of Asunción, Paraguay became a testing laboratory (COVID-Lab) for SARS-CoV-2. The COVID-Lab testing performance was assessed from 1 April 2020 to 12 May 2021. The effect of the pandemic on the IICS and how the COVID-Lab contributed to the academic and research activities of the institute were also assessed. IICS researchers and staff adjusted their work schedules to support the COVID-Lab. Of the 13,082 nasopharyngeal/oropharyngeal swabs processed, 2704 (20.7%) tested positive for SARS-CoV-2 by RT-PCR. Of the individuals testing positive, 55.4% were female and 48.3% were aged 21-40 years. Challenges faced by the COVID-Lab were unstable reagent access and insufficient staff; shifting obligations regarding research, academic instruction, and grantsmanship; and the continuous demands from the public for information on COVID-19. The IICS provided essential testing and reported on the progress of the pandemic. IICS researchers gained better laboratory equipment and expertise in molecular SARS-CoV-2 testing but struggled to manage their conflicting educational and additional research obligations during the pandemic, which affected their productivity. Therefore, policies protecting the time and resources of the faculty and staff engaged in pandemic-related work or research are necessary components of healthcare emergency preparedness.


Assuntos
COVID-19 , Humanos , Feminino , Masculino , COVID-19/diagnóstico , COVID-19/epidemiologia , COVID-19/prevenção & controle , SARS-CoV-2/genética , Teste para COVID-19 , Pandemias , Paraguai/epidemiologia , Vacinação
11.
Med. clin. soc ; 7(1)abr. 2023.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1422066

RESUMO

Introducción: diversos factores pueden influir en la mortalidad de pacientes hospitalizados por COVID-19. Objetivo: determinar la mortalidad y los factores asociados a esta en adultos con COVID-19 hospitalizados en la unidad de cuidados intensivos de un Hospital de Tercer Nivel de Paraguay. Metodología: estudio observacional, descriptivo, de asociación cruzada, de corte transversal y temporalmente retrospectivo. Se incluyó historias clínicas de pacientes adultos, de ambos sexos, que tenían diagnóstico confirmado (por prueba de antígeno y/o PCR) de infección por SARS-CoV-2 y que estaban hospitalizados en la unidad de cuidados intensivos de un Hospital General de Tercer Nivel de Paraguay. Resultados: Se incluyeron 116 pacientes, de los cuales el 54 % correspondió al sexo masculino. La edad media fue de 57±12,9 años. El 51 % tenía hipertensión arterial y el 29 % diabetes mellitus. El requerimiento de ventilación mecánica se dio en un 85% de pacientes. El 75 % de los pacientes ventilados tuvo un desenlace fatal. Se encontró una asociación estadísticamente significativa entre la presencia de infecciones bacterianas y requerimiento de hemodiálisis y el desenlace fatal (p=0,0074 y p=0,00011, respectivamente). La media de las edades de los pacientes fallecidos fue de 59,5 años, mientras que el grupo de pacientes que recibieron el alta desde la unidad de cuidados intensivos arrojó una media de 54,2 años. La diferencia entre estas edades en relación con el óbito fue significativa, con una p<0,05. Discusión: La mortalidad general debido a COVID-19 fue de más de 6 por cada 10 pacientes, siendo más alta en aquellos pacientes con ventilación. Aquellos pacientes que presentaron sobreinfección bacteriana o requirieron de hemodiálisis durante el curso de la hospitalización presentaron un peor desenlace en comparación con los pacientes que no presentaron este tipo de complicaciones.


Introduction: Several factors may influence mortality in patients hospitalized with COVID-19. Objective: This research aimed to determine mortality and associated factors in adults with COVID-19 hospitalized in the intensive care unit of a Third Level Hospital in Paraguay. Methodology: Observational, descriptive of cross-association, cross-sectional, and retrospective study. We included medical records of adult patients, of both sexes, who had a confirmed diagnosis (by antigen and/or PCR test) of SARS-CoV-2 infection and who were hospitalized in the intensive care unit of a Third Level General Hospital in Paraguay. Results: We included 116 patients, 54% of whom were male. The mean age was 57 ± 12.9 years. Of participants, 51% had hypertension and 29% diabetes mellitus. Mechanical ventilation was required in 85% of the patients. Of ventilated patients, 75% had a fatal outcome. A statistically significant association was found between the presence of bacterial infections and hemodialysis requirement and fatal outcome (p=0.0074 and p=0.00011, respectively). The mean age of the deceased patients was 59.5 years, while the group of patients discharged from the intensive care unit had a mean age of 54.2 years. The difference between these ages in relation to death was significant, with a p<0.05. Discussion: Overall mortality due to COVID-19 was more than 6 per 10 patients, being higher in those patients with ventilation. Those patients who presented bacterial superinfection or required hemodialysis during hospitalization had a worse outcome compared to patients who did not present this type of complications.

12.
Brain Sci ; 13(3)2023 Mar 04.
Artigo em Inglês | MEDLINE | ID: mdl-36979253

RESUMO

The COVID-19 pandemic has had a heavy impact on daily life, leading to physical and psychosocial consequences. Nowadays, clinicians and health researchers are particularly interested in describing and facing the long-term effects of COVID-19, also known as "long-COVID syndrome". Pandemic fatigue has been defined as a cluster of demotivation, tiredness, and psychological effects that emerge gradually over time after the infection or through the adoption of the recommended measures to combat it. In this study, we report the findings of a large survey conducted in South America involving 1448 participants (mean age: 33.9 ± 11.2 years old) from Argentina, Bolivia, Uruguay, Peru, and Paraguay. An online survey was launched through the common social media based on a specific assessment aimed to detect the prevalence of pandemic fatigue and associated factors. Socio-demographic characteristics, medical, and personal information were collected; the Pandemic Fatigue Scale (PFS) and the Coronavirus Anxiety Scale (CAS) were also administered. We found mid-levels of pandemic fatigue among respondents (21.7 ± 7.95 score at PFS) as well as significant anxiety related to the COVID-19 pandemic (1.56 ± 2.76 score at CAS). In addition, pandemic fatigue was significantly associated with the experience of the loss of a relative/friend due to COVID-19, anxiety related to the infection, and reliance on social media as a primary source of information on the pandemic. Vaccination significantly reduced the levels of fatigue among respondents. Our findings may add to the international debate regarding the long-term health consequences of the COVID-19 pandemic and strategies to manage them in the general population of South America.

14.
Rev. cient. cienc. salud ; 5(1): 1-6, 26-01-2023.
Artigo em Espanhol | BDNPAR | ID: biblio-1413358

RESUMO

Introducción. La pandemia por COVID-19 desde su inicio hasta el 13 de agosto de 2022, ha causado 19.478 muertes en Paraguay, con una tasa de letalidad de 2,78%. El objetivo del estudio es comparar las características de los pacientes fallecidos por COVID-19 en dos años, enero-diciembre, 2021 y enero-julio 2022. Material y Método.Estudio analítico retrospectivo de corte transverso de pacientes adultos y pediátricos fallecidos por COVID-19 confirmados por RT-PCR en hisopados nasofaríngeos que estaban internados en el área respiratoria del Hospital Nacional de Itauguá.Resultados. De 5265 pacientes internados con COVID-19, fallecieron 1512, siendo la letalidad global de 28,7%, en el 2021 fue 26,3% (1164/4423) y 41,3% (348/842) en el 2022. Hubo mayor porcentaje de varones (53,6%) entre los fallecidos, significativamente mayor (p=0.045) en el 2022 (58,3%) que en el 2021 (52,2%). El 69% de los fallecidos eran mayores de 60 años en el 2022 y 48,3% en 2021. El 79,2% de los pacientes tenía algún factor de riesgo, que fue mayor en el 2022 (84,3%) que en el 2021 (77,7%), sobre todo, HTA (54,3% vs 42,2%), cardiopatía (15,8% vs 9,7%), ERC (14,4% vs 5,4%), EPOC (11,5% vs 5,4%), inmunodeficiencia (6,3% vs 2,5%) y enfermedad neurológica (3,4% vs 1,5%). La necesidad de ARM fue significativamente (p <0,001) mayor en el 2022 (50,3%) que en el 2021 (31,1%). Conclusión. Se observó unaletalidad global elevada en un hospital de referencia en Paraguay con los predictores de mortalidad similares a lo reportado a nivel mundial.Palabras clave: mortalidad; COVID-19; factores de riesgo.


Introduction. The COVID-19 pandemic from its beginning until August 13, 2022, has caused 19,478 deaths in Paraguay with a fatality rate of 2.78%. The objective of the study is to compare the characteristics of patients who died from COVID-19 in two years, January-December 2021 and January-July 2022. Material and Method. A retrospective cross-sectional analytical study of adult and pediatric patients who died from COVID-19 hospitalized in the respiratory area of the hospital. The patients were confirmed by RT-PCR in nasopharyngeal swabs. Results.Out of 5265 patients hospitalized with COVID-19, 1512 died, yielding an overall lethality rate of 28.7%, in 2021 was 26.3% (1164/4423) and 41.3% (348/842) in 2022. There was a higher percentage of men (53, 6%) among the deceased, significantly higher (p=0.045) in 2022 (58.3%) thanin 2021 (52.2%); 69% of the deceased were over 60 years of age in 2022 and 48.3% in 2021; 79.2% of the patients had some risk factor, significantly higher in 2022 (84.3%) than in 2021 (77.7%), especially in AHT (54.3% vs 42.2%), heart disease (15.8% vs 9.7%), CKD (14.4% vs 5.4%), COPD (11.5% vs 5.4%), immunodeficiency (6.3% vs 2.5%) and neurological disease (3.4% vs 1.5%). The need for MRA was significantly (p <0.001) higher in 2022 (50.3%) than in 2021 (31.1%). Conclusion.A high global lethality rate was observed in a reference hospital in Paraguay with mortality predictors similar to those reported worldwide.


Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Criança , Adolescente , Adulto , Pessoa de Meia-Idade , Idoso , Idoso de 80 Anos ou mais , Mortalidade , Fatores de Risco , COVID-19
15.
Rev. cient. cienc. salud ; 5(1)26-01-2023.
Artigo em Espanhol | BDNPAR | ID: biblio-1413372

RESUMO

Introducción. La vacunación es una de las estrategias de salud pública más eficaces, sin embargo, puede producir efectos adversos (EA). En Paraguay, en diciembre del 2020, se lanzó el Plan Nacional de Vacunación como parte de las medidas de control y prevención contra la COVID-19, que contempla la vigilancia de eventos supuestamente atribuibles a la vacunación o inmunización (ESAVI). Objetivo. Determinar los EA de las vacunas contra la COVID-19 aplicadas en el Paraguay en el 2021. Metodología. Estudio analítico transversal que incluyó una encuesta en Google Forms difundida a través de las redes sociales. Se recolectaron variables sociodemográficas, tipo de vacuna, dosis y EA. Los datos se analizaron con Epi InfoTM, y se calculó Odd Ratio (OR) con su IC95% a un nivel de significancia de <0,05. Resultados. Participaron del estudio, 641 personas (edad media: 27 ± 13 años), 69% mujeres y 54% del departamento Central. El 75% recibió dos dosis de la vacuna, 56,3% presentó EA con la primera dosis y 45,7% con la segunda. La presencia de EA en la primera dosis se asoció con el sexo femenino (OR 1,73; IC95% 1,23­2,42; p=0,001) y edad menor de 30 años (OR 1,73; IC95% 1,30­2,46; p<0,001); presentar EA en la primera dosis estuvo asociada a presentarlos con la segunda dosis (OR 3,84, IC95% 2,39­5,09, p<0,001). Conclusión. Las reacciones adversas a las vacunas fueron frecuentes, pero leves y autolimitadas. Aquellos encuestados que presentaron EA en la primera dosis tuvieron mayor chance de volverlos a presentar en la segunda.


ntroduction. Vaccine is one of the most effective public health strategies, however, it can produce adverse effects (AE). In Paraguay, in December 2020, the National Vaccination Plan was launched as part of the control and prevention measures against COVID-19, which contemplates the surveillance of events supposedly attributable to vaccination or immunization (ESAVI). Objective.to determine the AE of the vaccines against COVID-19 used in Paraguay in 2021. Methodology. Cross-sectional analytical study using Google Forms for a survey disseminated through social networks. Sociodemographic variables, type of vaccine, doses, AE were collected. Data were analyzed with Epi InfoTM, Odds Ratio was calculated with a 95% CI, at a significance level of p value <0.05. Results. A total of 641 people participated in the study (mean age: 27 ± 13 years), 69% women and 54% from the Central Department. Seventy-five percent received two doses of the vaccine, 56.3% had AE with the first dose and 45.7% AE with the second. AE in the first dose was associated with females (OR 1.73 (95%CI 1.23­2.42); p=0.001) and age under 30 years old (OR 1.73; 95%CI 1.30­2.46; p <0.001); presenting AEs in the first dose was associated with presenting them with the second dose (OR 3.84; 95%CI 2.39­5.09; p<0.001). Conclusion. Adverse reactions to vaccines were common but mild and self-limited. Those respondents who presented AE in the first dose had a high chance of presenting them again in the second dose.


Assuntos
Humanos , Masculino , Feminino , SARS-CoV-2 , Paraguai , Vacinas contra COVID-19 , Vacina BNT162 , ChAdOx1 nCoV-19
16.
Rev. cient. cienc. salud ; 5(1): 1-8, 26-01-2023.
Artigo em Espanhol | LILACS, BDNPAR | ID: biblio-1511711

RESUMO

Introducción. Caracterizar la epidemia del SARS-CoV-2 en la comunidad puede aportar datos útiles a las autoridades en la toma de decisiones sobre las instituciones educativas en Paraguay. Objetivo. Describir las características epidemiológicas de la infección por SARS-CoV-2 en los hogares de escolares de tres instituciones de Asunción y departamento Central. Materiales y Métodos. Estudio descriptivo transversal realizado entre el 25 de octubre al 5 de noviembre de 2021. Se aplicaron encuestas estructuradas a los padres o encargados de escolares mediante un cuestionario en formato del formulario de Google enviado a través del WhatsApp desde la Dirección de las instituciones educativas. El cuestionario incluía preguntas sobre el número integrantes del hogar, datos demográficos del encuestado, número de personas con co-morbilidad, personas con COVID-19, con necesidad de hospitalización, número de fallecidos y vacunados contra COVID-19. Resultado. Se obtuvieron datos de 780 hogares, 379 (48,6%) de San Lorenzo, 217 (27,8) de Limpio, 93 (11,9%) de Asunción y 91 de otras localidades de Central (11,7%), el 18,6 % (731/3920) de los integrantes del hogar tuvo COVID-19, de ellos 9,7% (71/731) fue hospitalizado. La mortalidad fue de 0,79% (31/3920) y la letalidad 4,2% (31/731). El 52,7% (2340/3920) ya fue vacunado contra COVID-19 y el 88,2% (2065/2340) de ellos con dosis completa. Conclusión. La prevalencia de COVID-19 estuvo dentro del rango esperado para las infecciones sintomáticas con un alto índice de transmisión intradomiciliaria. Tanto la tasa de mortalidad como letalidad fueron consistentes con los datos nacionales. Palabras Clave: COVID-19; instituciones académicas; Paraguay; características de estudios epidemiológicos


Introduction. Characterizing the SARS-CoV-2 epidemic in the community can provide useful data for the authorities in making decisions on the educational institutions in Paraguay. Objective.To describe the epidemiological characteristics of SARS-CoV-2 infection in the homes of schoolchildren from three institutions in Asunción and the Central Department. Materials and Methods. Cross-sectional descriptive study carried out between October 25 and November 5, 2021. Structured surveys were applied to parents or guardians of schoolchildren through a questionnaire in the format of the Google form sent through WhatsApp from the Directorate of the educational institutions. The questionnaire included questions about the number of household members, demographic data of the respondent, number of people with co-morbidity, people with COVID-19, need of hospitalization, number of death and vaccinated against COVID-19. Results.Data from 780 households were obtained, 379 (48.6%) from San Lorenzo, 217 (27.8) from Limpio, 93 (11.9%) from Asunción and 91 from other localities from Central (11.7%); 18.6% (731/3920) of household members had COVID-19, of them 9.7% (71/731) were hospitalized. Mortality rate was 0.79% (31/3920) and lethality 4.2% (31/731). 52.7% (2,340/3,920) were already vaccinated against COVID-19 and 88.2% (2,065/2,340) of them fully vaccinated. Conclusion.The prevalence of infection was within the expected range for symptomatic COVID-19 infections with a high rate of intradomiciliary transmission. Both the hospitalization and fatality rates were within the range for the country. Key words: COVID-19; schools; Paraguay; epidemiologic study characteristics


Assuntos
Humanos , Masculino , Feminino , COVID-19 , Paraguai , Instituições Acadêmicas , Características de Estudos Epidemiológicos
17.
Vaccine ; 41(1): 109-118, 2023 01 04.
Artigo em Inglês | MEDLINE | ID: mdl-36404171

RESUMO

BACKGROUND: Data from previous studies of the MVC-COV1901 vaccine, a subunit vaccine against SARS-CoV-2 based on the stable prefusion spike protein (S-2P) adjuvanted with CpG 1018 adjuvant and aluminum hydroxide, suggest that the vaccine is generally safe and elicits a good immune response in healthy adults and adolescents. By comparing with AZD1222, this study adds to the findings from previous trials and further evaluates the breadth of protection offered by MVC-COV1901. METHODS: In this phase 3, parallel group, randomized, double-blind, active-controlled trial conducted in 2 sites in Paraguay, we assigned adults aged 18-91 years in a 1:1 ratio to receive intramuscular doses of MVC-COV1901 or AZD1222 administered as scheduled in the clinical trial. Serum samples were collected on the day of vaccination and 14 days after the second dose. Primary and secondary safety and immunogenicity endpoints were assessed. In addition, other outcomes investigated were cross-reactive immunity against the Omicron strain and the induction of IgG subclasses. RESULTS: A total of 1,030 participants underwent randomization. Safety data was derived from this set while primary immunogenicity data involved a per-protocol immunogenicity (PPI) subset including 225 participants. Among the participants, 58% are seropositive at baseline. When compared against AZD1222, MVC-COV1901 exhibited superiority in terms of neutralizing antibody titers and non-inferiority in terms of seroconversion rates. Reactogenicity was generally mild and no serious adverse event was attributable to MVC-COV1901. Both vaccines have a Th1-biased response predominated by the production of IgG1 and IgG3 subclasses. Omicron-neutralizing titers were 44.5 times lower compared to wildtype-neutralizing titers among seronegative individuals at baseline. This fold-reduction was 3.0 times among the seropositive. CONCLUSION: Safety and immunogenicity data of MVC-COV1901 from the study in Paraguay confirm previous results. The previous infection coupled with vaccination of this vaccine may offer protection against the Omicron strain though its durability is still unknown.


Assuntos
Vacinas contra COVID-19 , COVID-19 , Adulto , Adolescente , Humanos , Vacinas contra COVID-19/efeitos adversos , SARS-CoV-2 , ChAdOx1 nCoV-19 , COVID-19/prevenção & controle , Paraguai , Método Duplo-Cego , Imunoglobulina G , Adjuvantes Imunológicos , Vacinas de Subunidades , Imunogenicidade da Vacina , Anticorpos Antivirais , Anticorpos Neutralizantes
18.
J Ment Health ; 32(6): 1065-1072, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-34586935

RESUMO

BACKGROUND: There is an increasing concern regarding the mental health of healthcare workers during the COVID-19 pandemic. AIMS: This study aimed to assess the psychological impact of the COVID-19 exposure among Paraguayan healthcare workers. METHODS: A cross-sectional descriptive study has been carried out in five hospitals of Paraguay. Demographic and occupational exposure to COVID-19 were collected through a short questionnaire. Mental health status was assessed with the GAD-7, the PHQ-9, and the PCL-C. Logistic regression was used to determine psychological risk factors. RESULTS: 432 participants were surveyed. 218 (50.46%) were physicians. The prevalence of symptoms of anxiety, depression and PTSD was 48.15, 41.90, and 5.79%, respectively. There were no significant differences in anxiety (128 [29.63%] vs. 80 [18.52%]; p = 0.3303), depression (102 [23.61%] vs. 79 [18.29%]; p = 0.6703), or PTSD (14 [3.24%] vs. 11 [2.55%]; p = 0.8074) between frontline versus second-line workers. Main risk factors associated with psychological distress included work experience <5 years for depression and a COVID-19 positive diagnosis or having family/friends with a COVID-19 positive diagnosis for PTSD. CONCLUSIONS: Paraguayan healthcare workers reported high prevalence of anxiety, depression, and a low prevalence of PTSD. A positive diagnosis of COVID-19 and work experience <5 years are important psychological risk factors.


Assuntos
COVID-19 , Humanos , COVID-19/epidemiologia , Saúde Mental , SARS-CoV-2 , Pandemias , Estudos Transversais , Paraguai/epidemiologia , Depressão/epidemiologia , Depressão/etiologia , Pessoal de Saúde/psicologia , Ansiedade/epidemiologia , Ansiedade/etiologia , Fatores de Risco
19.
Esc. Anna Nery Rev. Enferm ; 27: e20220323, 2023.
Artigo em Português | LILACS, BDENF - Enfermagem | ID: biblio-1440101

RESUMO

Resumo Objetivo Compreender a atenção à saúde de puérperas em uma região de fronteira na vigência da pandemia por COVID-19. Método Pesquisa qualitativa do tipo Teoria Fundamentada nos Dados, vertente straussiana, realizada em região de fronteira, na atenção primária à saúde, com 30 participantes, que formaram três grupos amostrais entre mulheres, profissionais de saúde e gestores, por meio de entrevistas semiestruturadas, realizadas por chamada de voz e de forma presencial entre agosto de 2021 a maio de 2022. Resultados Identificaram-se cinco categorias, conforme modelo paradigmático, sendo elas: Identificando serviços de atenção ao puerpério; retornando para a atenção primária à saúde no puerpério; identificando fatores que interferiram no atendimento à puérpera; apontando estratégias para promoção da saúde no puerpério; e tendo uma atenção puerperal frágil. Conclusão e implicações para a prática Fragilidades existentes foram agravadas no curso da pandemia por COVID-19. Recomenda-se qualificar a contrarreferência para garantir a continuidade da atenção puerperal em tempo oportuno; o teleatendimento para viabilizar o acompanhamento, quando condições epidemiológicas forem de risco para a saúde materna; políticas públicas podem fortalecer a assistência a estrangeiras e migrantes em região de fronteira.


Resumen Objetivo Comprender la atención a la salud de puérperas en una región fronteriza durante la presencia de la pandemia por COVID-19. Método Investigación cualitativa del tipo Teoría Fundamentada, vertiente straussiana, realizada en una región fronteriza, en atención primaria de salud, con 30 participantes, que conformaron tres grupos muestrales entre mujeres, profesionales de la salud y directivos, a través de entrevistas semiestructuradas, realizadas por llamada de voz y personal directivo entre agosto de 2021 y mayo de 2022. Resultados Se identificaron cinco categorías, de acuerdo con el modelo paradigmático: Identificar los servicios de atención al puerperio; volver a la atención primaria de salud en el puerperio; identificar los factores que interfirieron en la atención puérpera; señalar estrategias para la promoción de la salud en el puerperio; teniendo un cuidado puerperal frágil. Conclusión e implicaciones para la práctica las debilidades existentes fueron exacerbadas en el curso de la pandemia por COVID-19. Se recomienda calificar la contrarreferencia para asegurar la continuidad de la atención puerperal en tiempo y forma; el teleservicio para permitir el seguimiento, cuando las condiciones epidemiológicas representen un riesgo para la salud materna; Las políticas públicas pueden fortalecer la atención a los extranjeros y migrantes en la región fronteriza.


Abstract Objective To understand the health care of puerperal women in a border region during the COVID-19 pandemic. Method Grounded Theory qualitative research, straussian strand, conducted in a border region, in primary health care, with 30 participants, who formed three sample groups among women, health professionals, and managers through semi-structured interviews conducted by voice call and in-person between August 2021 and May 2022. Results Five categories were identified, according to the paradigmatic model, namely: Identifying postpartum care services; returning to primary health care in the postpartum; identifying factors that interfered in the care of postpartum women; pointing out strategies for health promotion in the postpartum period; and having fragile postpartum care. Conclusion and implications for practice Existing weaknesses were exacerbated during the pandemic by COVID-19. It is recommended to qualify the counter-referral to ensure continuity of postpartum care on time; teleservice to enable follow-up when epidemiological conditions pose a risk to maternal health; public policies can strengthen assistance to foreign women and migrants in the border region.


Assuntos
Humanos , Feminino , Cuidado Pós-Natal , Saúde na Fronteira , Serviços de Saúde Materno-Infantil , Paraguai , Brasil , Aleitamento Materno , Centros de Saúde , Acesso aos Serviços de Saúde , Visita Domiciliar
20.
Med. clin. soc ; 6(3)dic. 2022.
Artigo em Espanhol | LILACS-Express | LILACS | ID: biblio-1422062

RESUMO

Introducción: Para la contención de la pandemia causada por la enfermedad del coronavirus (COVID-19) se aplicaron una serie de medidas sanitarias a toda la población, como el distanciamiento social, cierre de fronteras y cuarentena en el hogar. Dichas medidas, además, pudieron haber repercutido en un deterioro de la salud en general, un aumento del consumo de bebidas alcohólicas y otras sustancias para contrarrestar o reducir la intensidad de su respuesta a estas consecuencias. Objetivo: Determinar las características demográficas del consumo de riesgo para alcohol durante el tiempo de cuarentena estricta por la pandemia de covid-19. Metodología: Estudio observacional analítico de corte transverso tipo exploratorio. Constó de 16.538 encuestas virtuales realizadas a personas mayores de edad pertenecientes a todo el territorio nacional entre junio y septiembre del 2020. Se excluyó a 219 encuestados por no cumplir criterios de inclusión o datos incorrectamente llenados. Se determinó el consumo de riesgo mediante una prueba que calificaba el consumo por puntajes. Más de 5 puntos para hombres, más de 4 para mujeres. Resultados: 12224 participantes adultos (18-65 años) con una media de 31,9 años (±9,2), formaron parte del análisis, con predominio de participación masculina 64,5% (n=10531). El 74,9% (n=12224) proveniente del Eje Metropolitano. Según géneros, el OR fue 1,15 IC95 (1,08 - 1,23), vp=0,001. Al comparar nivel educativo, secundaria completa/incompleta, el OR fue 1,56 IC95 (1,19 - 2,06), vp=0,001. Y al comparar por ejes de residencias el OR fue 0,83 IC95 (0,77 - 0,89), vp=0,001. Discusión: Se pudo observar que, durante el tiempo de cuarentena, el consumo de alcohol crecía conforme el nivel educativo de la población aumentaba. Los hombres presentaron un consumo de riesgo mayor que los hombres. Conocer este comportamiento ayudaría a plantear acciones que ayuden a prevenir el consumo de alcohol en el grupo de mayor riesgo.


Introduction: The impact of the outbreak of pandemic proportions of COVID-19 has initiated several health and social measures worldwide. Thus, there is growing concern about the consequences of preventive social confinement associated with the pandemic due to the potential increase in the consumption of alcohol and other harmful substances. Between 2010-2014, in Paraguay approximately 5% of deaths over 15 years of age are attributable to alcohol consumption and are associated with external cause injuries, cancers, liver disease, cardiovascular diseases, addictions and domestic violence. Early detection and treatment are recommended intervention strategies to prevent these consequences. Objective: To determine the demographic characteristics of alcohol risk consumption during the covid-19 pandemic quarantine period. Methods: Analytical cross-sectional, exploratory observational study. It consisted of 16,538 virtual surveys carried out on persons of legal age throughout the national territory between June and September 2020. A total of 219 respondents were excluded for not meeting the inclusion criteria or for incorrectly filled out data. Risk consumption was determined using a test that rated consumption by scores. More than 5 points for men, more than 4 for women. Results: 12224 adult participants (18-65 years old) with a mean age of 31.9 years (±9.2), were part of the analysis, with a predominance of male participation 64.5% (n=10531). The 74.9% (n=12224) came from the Metropolitan Axis. According to gender, the OR was 1.15 CI95 (1.08 - 1.23), pv=0.001. When comparing educational level, high school complete/incomplete, the OR was 1.56 CI95 (1.19 - 2.06), pv=0.001. And when comparing by axes of residence, the OR was 0.83 CI95 (0.77 - 0.89), pv=0.001. Discussion: It was observed that, during the quarantine period, alcohol consumption increased as the educational level of the population increased. Males presented a higher risk consumption than males. Knowing this behavior would help to propose actions to help prevent alcohol consumption in the most at-risk group.

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