Clonal relation and antimicrobial resistance pattern of extended-spectrum ß-lactamase- and AmpC ß-lactamase-producing Enterobacter spp. isolated from different clinical samples in Tehran, Iran
Rev. Soc. Bras. Med. Trop
; 51(1): 88-93, Jan.-Feb. 2018. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1041448
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract INTRODUCTION:
Here, we determined the genes encoding antibiotic resistance enzymes and virulence factors and evaluated the genetic relationship between Enterobacter spp. isolated from different clinical samples.METHODS:
A total of 57 clinical isolates of Enterobacter spp. were tested for the production of extended-spectrum β-lactamases (ESBLs), carbapenemase, and AmpC using phenotypic and genotypic methods.RESULTS:
The most common ESBLs and AmpC β-lactamases were bla TEM (63.3%) and bla EBC (57.7%), respectively. The most prevalent virulence gene was rpos (87.7%). The random amplified polymorphic DNA (RAPD) patterns of strains were genetically unrelated.CONCLUSIONS:
RAPD polymerase chain reaction analysis revealed high genetic diversity among isolates.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Doenças Negligenciadas
/
Zoonoses
Base de dados:
LILACS
Assunto principal:
Proteínas de Bactérias
/
Beta-Lactamases
/
Escherichia coli
/
Fezes
/
Antibacterianos
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Rev. Soc. Bras. Med. Trop
Assunto da revista:
Medicina Tropical
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Irã
Instituição/País de afiliação:
Kerman University of Medical Sciences/IR
/
Tehran University of Medical Sciences/IR