Perfil clínico e radiológico de pacientes com tumor de wilms em um hospital pediátrico do sul do Brasil, 2010­2017 / Clinical and radiological profile of patients with wilms tumor in a pediatric hospital in the south of Brazil, 2010­2017

RESUMO

O tumor de Wilms, também denominado nefroblastoma, é o tumor maligno abdominal mais comum na infância. O objetivo do estudo foi descrever o perfil clinico e radiológico dos pacientes com diagnóstico de tumor de Wilms internados no Hospital Infantil Joana de Gusmão, Florianópolis/SC. Trata-se de um estudo descritivo, realizado durante o período de janeiro de 2010 a dezembro de 2017, que incluiu 33 pacientes com o diagnóstico de tumor de Wilms. Os dados foram analisados no programa Statistical Package for the Socials Sciences. Version 18.0. As variáveis categóricas foram expressas em frequência (simples e relativa). Observou-se que a maioria dos pacientes era do sexo masculino (57,6%), com idade do diagnóstico entre 3 e 5 anos (45,5%), procedentes da Grande Florianópolis (45,5%). Entre os dados clínicos encontrou-se massa abdominal (78,8%), dor (51,1%) e acometimento do rim direito (60,6%). O estadiamento International Society of Paediatric Oncology no estágio III (37,5%) e tipo histológico favorável (87,5%). Nos estudos de imagem tomográfica o tamanho longitudinal >10 cm (71,4%), tamanho antero-posterior entre 5 e 10 cm (53,6%), acometimento de veia cava inferior (3%), calcificações (6,1%) metástase hepática (12,1%) e pulmonar (9,1%). O estudo possibilitou traçar o perfil clinico e radiológico dos pacientes com tumor de Wilms do Hospital Infantil Joana de Gusmão e verificou a similaridade com os resultados encontrados na literatura.

ABSTRACT

Wilms tumor, also called nephroblastoma, is the most common abdominal malignancy in childhood. This research aims to describe the clinical and radiological profile of patients diagnosed with Wilms tumor hospitalized at Joana de Gusmão Children's Hospital, in Florianópolis-Santa Catarina. This is a descriptive study, conducted from January 2010 to December 2017, carried out with 33 patients diagnosed with Wilms tumor. The data were analyzed with the SPSS 18.0 program. Categorical variables were expressed in simple and relative frequency. It was observed that most patients were male (57.6%), aged, when diagnosed, between 3 and 5 (45.5%), coming from the Greater Florianópolis (45.5%). Clinical data included abdominal mass (78.8%), pain (51.1%) and involvement of the right kidney (60.6%). Stage III International Society of Paediatric Oncology staging (37.5%) and favorable histological type (87.5%). In tomographic imaging studies, the longitudinal size was >10 cm (71.4%), anteroposterior size between 5 and 10 cm (53.6%), inferior vena cava involvement (3%), calcifications (6.1 %) hepatic (12.1%) and pulmonary (9.1%) metastasis. The study enabled the researchers to trace the clinical and radiological profile of patients with Wilms tumor of the Joana de Gusmão Children's Hospital and verified the similarity with the results found in the literature.