Modeling of lactose enzymatic hydrolysis using Monte Carlo method
Electron. j. biotechnol
; 40: 78-83, July. 2019. tab, graf, ilus
Artigo
em Inglês
| LILACS
| ID: biblio-1053493
Biblioteca responsável:
CL1.1
ABSTRACT
Background:
Mathematical modeling is useful in the analysis, prediction, and optimization of an enzymatic process. Unlike the conventional modeling methods, Monte Carlo method has special advantages in providing representations of the molecule's spatial distribution. However, thus far, Monte Carlo modeling of enzymatic system is namely based on unimolecular basis, not suitable for practical applications. In this research, Monte Carlo modeling is performed for enzymatic hydrolysis of lactose for the purpose of real-time applications.Results:
The enzyme hydrolysis of lactose, which is conformed to MichaelisMenten kinetics, is modeled using the Monte Carlo modeling method, and the simulation results prove that the model predicts the reaction kinetics very well.Conclusions:
Monte Carlo modeling method can be used to model enzymatic reactions in a simple way for real-time applications.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Método de Monte Carlo
/
Enzimas
/
Hidrólise
/
Lactose
Tipo de estudo:
Avaliação econômica em saúde
/
Estudo prognóstico
Idioma:
Inglês
Revista:
Electron. j. biotechnol
Assunto da revista:
Biotecnologia
Ano de publicação:
2019
Tipo de documento:
Artigo
País de afiliação:
China
Instituição/País de afiliação:
Shandong Academy of Chinese Medicine/CN
/
Shandong Academy of Pharmaceutical Sciences/CN
/
Shandong Normal University/CN
/
Shandong University/CN
/
Shandong Yian Biotechnology Co/CN