The unmet needs: How future technologies will address current limitations of bioresorbable scaffold technology
Catheter Cardiovasc Interv
; 88(S1): 54-59, 2016.
Article
em En
| SES-SP, SESSP-IDPCPROD, SES-SP
| ID: biblio-1061856
Biblioteca responsável:
BR79.1
Localização: BR79.1
ABSTRACT
First-generation bioresorbable scaffolds (BRS), represented by the three marked-approved devices (Absorb BVS 1.1, DESolve NX, and DREAMS) have demonstrated, in low to moderate angiographic scenarios, similar efficacy to current generation metallic drug-eluting stents. However, a trend toward more device thrombosis have been observed, especially when the scaffolds are used in off-label situations. Among the main shortcomings of this novel technology, we highlight (1) Increased strut thickness (≥150 μm) and crossing profile; (2) low resistance to overexpansion; (3) lack of radiopacity, and; (4) special storage requirements. In order to overcome these limitations and improve their acute performance and midterm safety, a dozen of novel BRS are currently under research, in different stages of development. In the present review, we address three of these new technologies, pointing out their innovative features and initial clinical results...
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Coleções:
06-national
/
BR
Base de dados:
SES-SP
/
SESSP-IDPCPROD
Assunto principal:
Doença da Artéria Coronariana
/
Stents Farmacológicos
Idioma:
En
Revista:
Catheter Cardiovasc Interv
Ano de publicação:
2016
Tipo de documento:
Article