Renal Failure as a Determinant of Mortality After Cardiac Transplantation

ABSTRACT

Introduction. Patients with heart failure frequently develop renal failure, which increasesthe mortality rate among patients undergoing cardiac transplantation.Purpose. To determine whether preoperative renal function influenced postoperativemortality in cardiac transplantation recipients.Materials and Methods. The measurements of plasma urea, plasma creatinine, and 24-hour creatinine clearance in patients who underwent cardiac transplantation werecorrelated with mortality at 30, 90, and 365 days after the procedure, using Student t test for continuous variables and the chi-square test for categorical variables.Results. All variables correlated with mortality, particularly plasma creatinine at 30, 90,and 365 days (P .029, .003, and .0029, respectively).Conclusion. Preoperative renal failure is a mortality indicator in cardiac transplantation recipients.