Relationship between alcoholism addiction and periodontitis. an in vivo study using drinking-in-darkness protocol in rats
J. oral res. (Impresa)
; 7(2): 55-60, feb. 18, 2018. tab, graf, ilus
Artigo
em Inglês
| LILACS
| ID: biblio-1120423
Biblioteca responsável:
CL30.1
ABSTRACT
Periodontal disease (PD) has been considered a probable risk factor for several systemic diseases. among them, PD is presumed to be one of the possible etiologies of chronic illness of the central nervous system. In this context, poor oral health and PD is associated with substance abuse in humans. however, if periodontal lesions can produce addiction is unknown. this paper aims to evaluate the possibility that chronic periodontal injury (CPL) can cause ethanol binge intake in drink-in-darkness (DID) protocol in rats. in CPL group (n=10) experimental damage was done to the periodontal tissue of the second maxillary molar, the control group (n=9) received sham injury. forty-three days after CPL the intake of ethanol was assessed using several concentrations in DID experiment. during the DID experiment, we observed significant differences between the binge-type consumption of ethanol at the lowest concentration of 10 percent (p=0.01). differences in consumption of 20 percent ethanol are observed during a few days (p=0.04), and there are no differences in consumption at 40 percent concentration of ethanol (p=0.2). it is concluded that chronic periodontal lesion leads to alcoholism in wistar rats.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Doenças Periodontais
/
Alcoolismo
/
Periodontite Crônica
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Limite:
Animais
Idioma:
Inglês
Revista:
J. oral res. (Impresa)
Assunto da revista:
Odontologia
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
México
Instituição/País de afiliação:
UNAM/MX