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Protein Profiles of Individuals with Erosive Tooth Wear
Mulic, Aida; Tveit, Anne Bjorg; Vieira, Nicholas Modesto; Limesand, Kirsten; Vieira, Alexandre Rezende.
Afiliação
  • Mulic, Aida; s.af
  • Tveit, Anne Bjorg; s.af
  • Vieira, Nicholas Modesto; University of Pittsburgh. School of Dental Medicine. Department of Oral Biology. Pittsburgh. US
  • Limesand, Kirsten; University of Arizona. Department of Nutritional Sciences. Tucson. US
  • Vieira, Alexandre Rezende; University of Pittsburgh. School of Dental Medicine. Department of Oral Biology. Pittsburgh. US
Article em En | LILACS, BBO | ID: biblio-1135483
Biblioteca responsável: BR1264.1
ABSTRACT
Abstract

Objective:

To determine if protein profiles identified in saliva could be used to determine risk and severity of erosive tooth wear. Material and

Methods:

Three types of saliva sampling were performed to obtain saliva from 34 18-year old individuals that received regular dental check-ups, along with clinical status of the dentition and risk factor related to erosive tooth wear using the VEDE scale. Protein profiles in saliva were determined using electrophoresis and the calculation of the percentage of a specific band at a specific molecular weight in relationship to the total protein in that sample (% of total) using molecular weight standards. This quantification was repeated for each protein band across a range of molecular weights for each sample to test for association with erosive tooth wear status.

Results:

There were no differences in the number of detectable proteins sourced from the parotid gland, nor the unstimulated and stimulated whole saliva. Five out of the 34 individuals had no signs of erosive tooth wear despite an acidic diet and were more likely to have proteins with molecular weight smaller than 1 KDa (p=0.03).

Conclusion:

There is potential for the use of protein profiling to determine risks for erosive tooth wear.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: BBO / LILACS Assunto principal: Erosão Dentária / Fatores de Risco / Cárie Dentária / Esmalte Dentário / Desgaste dos Dentes Tipo de estudo: Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Assunto da revista: ODONTOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: BBO / LILACS Assunto principal: Erosão Dentária / Fatores de Risco / Cárie Dentária / Esmalte Dentário / Desgaste dos Dentes Tipo de estudo: Etiology_studies / Guideline / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Female / Humans / Male País/Região como assunto: Europa Idioma: En Revista: Pesqui. bras. odontopediatria clín. integr Assunto da revista: ODONTOLOGIA Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Brasil