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Bellini duct carcinoma
Falcão, Gil; Parmanande, Anuraj Quiran; Araújo, Catarina; Barreira, João Vasco.
Afiliação
  • Falcão, Gil; Centro Hospitalar Universitário Lisboa Central. Urology Department. Lisboa. PT
  • Parmanande, Anuraj Quiran; Centro Hospitalar Universitário Lisboa Central. Medical Oncology Department. Lisboa. PT
  • Araújo, Catarina; Centro Hospitalar Universitário Lisboa Central. Pathological Anatomy Department. Lisboa. PT
  • Barreira, João Vasco; Centro Hospitalar Universitário Lisboa Central. Medical Oncology Department. Lisboa. PT
Autops. Case Rep ; 11: e2020230, 2021. graf
Article em En | LILACS | ID: biblio-1142409
Biblioteca responsável: BR26.7
ABSTRACT
The modern era has brought an appreciation that renal cell carcinoma (RCC) includes diverse subtypes derived from the various parts of the nephron, each with its distinctive genetic basis and tumor biology. Carcinoma of the collecting ducts of Bellini (CDC) is a rare subtype of RCC, with a predictably poor prognosis. This rare subtype represents less than 1% of all kidney carcinomas. It derives from presumably numerous chromosomal losses. It is of chief importance to differentiate CDC from other types of renal cell cancer. Typically, it is characterized by a firm, centrally located tumor with infiltrative borders. Regarding the histopathologic characteristics, we can find complex, highly infiltrative cords with inflamed (desmoplastic) stroma, with high-grade nuclei and mitoses. Most reported cases of CDC had been high grade, advanced stage, and unresponsive to conventional therapies. This rare form of disease highlights the importance of multidisciplinary teams in the management of cancer patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Carcinoma de Células Renais / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans Idioma: En Revista: Autops. Case Rep Assunto da revista: Anatomia / Patologia Cl¡nica / Patologia Legal Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Portugal

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Carcinoma de Células Renais / Neoplasias Renais Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans Idioma: En Revista: Autops. Case Rep Assunto da revista: Anatomia / Patologia Cl¡nica / Patologia Legal Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Portugal