Ultrastructural Changes in Ascaris Suum after Oxibendazole Treatment

ABSTRACT

The effect of oxibendazole treatment on adult Ascaris suum was assessed using scanning and transmission electron microscopy. The changes included collapse of the lip papillae; rupture of buccal cavity cuticle; prolapse of the pharynx; degeneration of epithelial cells and erosion of microvilli. Theses changes may lead to impaired digestion and absorption of nutrients and cause cellular autolysis; resulting in the death of the worm