The impact of visceral fat and levels of vitamin D on coronary artery calcification
Rev. Assoc. Med. Bras. (1992)
; 67(1): 88-93, Jan. 2021. tab, graf
Article
em En
| LILACS
| ID: biblio-1287778
Biblioteca responsável:
BR1.1
ABSTRACT
SUMMARY OBJECTIVE:
To evaluated calcification of the coronary arteries and its association with visceral fat and 25-hydroxyvitamin D (25(OH)D) serum levels.METHODS:
A cross sectional study involving 140 individuals without any previous diagnosis of cardiovascular disease. A biochemical analysis of vitamin D serum levels was carried out, as well as computed tomography to measure coronary artery calcium score and visceral adipose tissue.RESULTS:
The mean age of the individuals was 55.9 (±12.4). Coronary artery calcium was observed in 40.7% of the population. Vitamin D presented median serum levels of 30.4 ng/ml (IQ24.5-39.1), with 14,1 and 33.7% of the individuals presenting deficiency and insufficiency, respectively. In the univariate analysis, the calcium score was more prevalent in aged patients (p<0.01), in hypertensive individuals (p<0.01), in diabetics (p=0.02), and in those with a higher concentration of VAT (p=0.02). In the adjusted analysis, it was found that the highest concentration of VAT (OR 4.0; 95%CI 1.4-11.7), hypertension (OR 4.8; 95%CI 1.5-15.3), and age (OR 10.4; 95%CI 3.9-27.6) were predictors of subclinical atherosclerosis, regardless of body mass index, diabetes, and 25OHD.CONCLUSIONS:
Excess visceral fat was associated with subclinical atherosclerosis, regardless of other risk factors for cardiovascular disease. Serum levels of 25OHD were not associated with CAD in its early stages.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
Assunto principal:
Deficiência de Vitamina D
/
Doença da Artéria Coronariana
Tipo de estudo:
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
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Risk_factors_studies
Limite:
Aged
/
Humans
Idioma:
En
Revista:
Rev. Assoc. Med. Bras. (1992)
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Brasil