Retrospective analysis on efficacy of convalescent plasma in acute respiratory distress syndrome due to COVID-19
São Paulo med. j
; 140(1): 12-16, Jan.-Feb. 2022. tab
Artigo
em Inglês
| LILACS
| ID: biblio-1357469
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT BACKGROUND:
Coronavirus disease 2019 (COVID-19) is an ongoing global health threat. However, currently, no standard therapy has been approved for the disease.OBJECTIVES:
To evaluate the clinical effectiveness of convalescent plasma (CP) in patients with acute respiratory distress syndrome (ARDS) due to COVID-19. DESIGN ANDSETTING:
Retrospective study conducted at Kayseri City Education and Research Hospital, Kayseri, Turkey.METHODS:
The case group consisted of adult patients (> 18 years) with ARDS due to COVID-19 who received CP in combination with antiviral and supportive treatment. These patients were compared with others who only received antiviral and supportive treatment.RESULTS:
During the study period, a total of 30 patients with ARDS due to COVID-19 were included. Eleven patients (36%) received CP in combination with antiviral and supportive treatment, whereas nineteen patients (64%) in the control group only received antiviral and supportive treatment. On admission, the median age, demographic and clinical data and initial laboratory test results were similar between the groups (P > 0.05). On the 14th day of treatment, the laboratory values remained similar between the groups (P > 0.05). The mortality rates were not significantly different between the groups.CONCLUSION:
CP treatment did not affect mortality or lead to clinical improvement for COVID-19 patients with ARDS.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Contexto em Saúde:
ODS3 - Meta 3.8 Atingir a cobertura universal de saúde
/
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
/
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Arranjos de Entrega
/
Meta 3.8 Atingir a cobertura universal de saúde
/
COVID-19
/
Pneumonía
/
Outras Doenças Respiratórias
Base de dados:
LILACS
Assunto principal:
Síndrome do Desconforto Respiratório do Recém-Nascido
/
COVID-19
Tipo de estudo:
Estudo observacional
Limite:
Adulto
/
Humanos
Idioma:
Inglês
Revista:
São Paulo med. j
Assunto da revista:
Cirurgia Geral
/
Cincia
/
Ginecologia
/
Medicina
/
Medicina Interna
/
Obstetr¡cia
/
Pediatria
/
Sa£de Mental
/
Sa£de P£blica
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Turquia
Instituição/País de afiliação:
Erciyes Üniversitesi Tip Fakültesi/TR
/
Kayseri City Education and Research Hospital/TR
/
University of Health Sciences/TR