SARS-CoV-2 testing among patients and healthcare professionals in an HIV outpatient clinic in Brazil
Rev. Inst. Med. Trop. São Paulo (Online)
; 64: e3, 2022. tab
Article
em En
|
LILACS-Express
| LILACS
| ID: biblio-1360803
Biblioteca responsável:
BR1.1
ABSTRACT
ABSTRACT The COVID-19 pandemic in Brazil has been marked by high infection and death rates. The immune response generated by current vaccination might be influenced by previous natural infection, and baseline estimates may help in the evaluation of vaccine-induced serological response. We evaluated previous SARS-CoV-2 testing (RT-PCR), and performed rapid diagnostic tests (RDT) and high throughput electrochemiluminescence immunoassay (ECLIA) before vaccination among people living with HIV (PLWH), users of antiretroviral prophylaxis (PrEP/PEP), and healthcare professionals in an HIV outpatient clinic (HCP-HC). RDT was positive in 25.7% (95% CI 19-33%) overall, 31.3% (95% CI 18-45%) among PLWH, 23.7% (95% CI 14-34%) in PrEP/PEP users and 21.4% (95% CI 05-28%) in HCP-HC (p=0.548). Diagnostic RT-PCR testing was very limited, even for symptomatic individuals, and whereas all HCP-HC had one test perfomed, only 35% of the patients (PREP/PEP/PLWH) were tested (p<0.0001). Adequate monitoring of post-vaccination humoral response and breakthrough infections including those in asymptomatic cases are warranted, especially in immunologically compromised individuals.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
LILACS
País/Região como assunto:
America do sul
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Brasil
Idioma:
En
Revista:
Journal of the São Paulo Institute of Tropical Medicine
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Rev Inst Med Trop Sao Paulo
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Rev. Inst. Med. Trop. São Paulo (Online)
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Rev. Inst. Med. Trop. Säo Paulo
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Revista do Instituto de Medicina Tropical de São Paulo (Impresso)
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Revista do Instituto de Medicina Tropical de São Paulo (Online)
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Revista do Instituto de Medicina Tropical de Säo Paulo (Impresso)
Assunto da revista:
Medicina Tropical
Ano de publicação:
2022
Tipo de documento:
Article
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Project document
País de afiliação:
Brasil
País de publicação:
Brasil