Incidence and factors associated with pulmonary embolism among RT-PCR confirmed Covid-19 patients with upfront CT pulmonary angiography in Ethiopia: A nested case-control study
Ethiop. med. j. (Online)
; 61(1): 1-13, 2023.
Artigo
em Inglês
| AIM (África)
| ID: biblio-1416376
Biblioteca responsável:
CG1.1
ABSTRACT
Introduction:
Pulmonary embolism is one of the complications of COVID-19, with reported incidence ranging from 3 to 33 % in non-ICU patients to as high as 40% among ICU patients. Since the clinical presentations of COVID-19 and Pulmonary embolism overlap, it is difficult to differentiate between these cases. This study aimed to assess the incidence of pulmonary embolism and associated factors among confirmed Covid-19 Patients in Ethiopia.Methods:
A nested case control study was conducted among 131 patients with COVID-19 (40 COVID-19 patients with Pulmonary embolism and 91 COVID-19 patients with no PE) who were on follow up from May, 2021 to May, 2022. Data was summarized using frequencies with percentages. A chi-square test/ Fisher's exact test was run to determine the presence of a significant difference between the exposure variables and the development of PE. To identify factors associated with the development of Pulmonary embolism, a multivariable Binary Logistic Regression model with sensitivity analysis was run.Results:
The incidence of PE was 30.5% (95% CI, 22.9% - 37.4%) in the cohort of patients for whom upfront CTPA was performed. The Chi-square/ Fisher's exact test results showed a significantly higher proportion of patients with PE tend to present with shortness of breath, chest pain and anosmia/ageusia than those with no PE. However, in a subsequent regression analysis, only chest pain was found to be significantly associated with the development of PE in COVID-19 patients (AOR= 3.24, 95% CI= 1.10, 9.54, p-value=0.033).Conclusion:
The incidence of PE among COVID-19 patients was found to be relatively lower than reports from other countries. Having chest pain was found to be a significant factor that indicates the development of PE, implying that in a setting where performing upfront CTPA is not practical, detailed symptom inquiry could serve as an important clinical criteria.
Texto completo:
Disponível
Contexto em Saúde:
Agenda de Saúde Sustentável para as Américas
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ODS3 - Saúde e Bem-Estar
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ODS3 - Meta 3.3 Acabar com as doenças tropicais negligenciadas e combater as doenças transmissíveis
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ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Objetivo 9: Redução de doenças não transmissíveis
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Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis
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COVID-19
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Pneumonía
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Outras Doenças Respiratórias
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Tromboembolismo Venoso
Base de dados:
AIM (África)
Assunto principal:
COVID-19
Tipo de estudo:
Estudo diagnóstico
/
Estudo de incidência
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Estudo observacional
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Estudo prognóstico
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Fatores de risco
Idioma:
Inglês
Revista:
Ethiop. med. j. (Online)
Ano de publicação:
2023
Tipo de documento:
Artigo
Instituição/País de afiliação:
Delanta Primary Hospital/ET
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Department of Internal Medicine, MuluG Health Services/ET
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Department of Internal Medicine, Ras Desta Damtew Memorial Hospital/ET
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Medical Research Lounge (Research Consultancy and Training Center)/ET