Smoking intensity increases diaphragm muscle injury: a clinicopathologic study
J. clin. med
; 12(11): e3823, June 2023. ilus, tab
Article
em En
| CONASS, SES-SP, SESSP-IDPCPROD, SES-SP
| ID: biblio-1437642
Biblioteca responsável:
BR79.1
ABSTRACT
BACKGROUND:
Studying the effects of smoking intensity is important to evaluate the risk of tobacco use on a range of illnesses, such as sarcopenia among the elderly. Thus, this study aimed to analyze the effects of pack-years of cigarette smoking on the diaphragm muscle (DIAm) histopathology of postmortem samples.METHODS:
Subjects were divided into three groups never-smoker (n = 46); less than 30 pack-years of smoking (n = 12); and more than 30 pack-years of smoking (n = 30). Diaphragm samples were stained with Picrosirius red and hematoxylin and eosin stain for general structure.RESULTS:
Participants with more than 30 pack-years of cigarette smoking had a significant increase in adipocytes, blood vessels and collagen deposit, as well as an increase in histopathological alterations.CONCLUSIONS:
Pack-years of smoking was associated with DIAm injury. However, further clinicopathological studies are needed to confirm our findings.
Texto completo:
1
Coleções:
06-national
/
BR
Base de dados:
CONASS
/
SES-SP
/
SESSP-IDPCPROD
Assunto principal:
Diafragma
/
Produtos do Tabaco
Idioma:
En
Revista:
J. clin. med
Ano de publicação:
2023
Tipo de documento:
Article