Your browser doesn't support javascript.
loading
Evaluating the current state of the art of Huntington disease research: a scientometric analysis
Barboza, LA; Ghisi, NC.
Afiliação
  • Barboza, LA; Universidade Tecnológica Federal do Paraná. Laboratório de Biologia Molecular. Dois Vizinhos. BR
  • Ghisi, NC; Universidade Tecnológica Federal do Paraná. Laboratório de Biologia Molecular. Dois Vizinhos. BR
Braz. j. med. biol. res ; 51(3): e6299, 2018. graf
Article em En | LILACS | ID: biblio-889050
Biblioteca responsável: BR1.1
ABSTRACT
Huntington disease (HD) is an incurable neurodegenerative disorder caused by a dominant mutation on the 4th chromosome. We aim to present a scientometric analysis of the extant scientific undertakings devoted to better understanding HD. Therefore, a quantitative study was performed to examine the current state-of-the-art approaches that foster researchers' understandings of the current knowledge, research trends, and research gaps regarding this disorder. We performed literature searches of articles that were published up to September 2016 in the "ISI Web of Science™" (http//apps.webofknowledge.com/). The keyword used was "Huntington disease". Of the initial 14,036 articles that were obtained, 7732 were eligible for inclusion in the study according to their relevance. Data were classified according to language, country of publication, year, and area of concentration. The country leader regarding the number of studies published on HD is the United States, accounting for nearly 30% of all publications, followed by England and Germany, who have published 10 and 7% of all publications, respectively. Regarding the language in which the articles were written, 98% of publications were in English. The first publication to be found on HD was published in 1974. A surge of publications on HD can be seen from 1996 onward. In relation to the various knowledge areas that emerged, most publications were in the fields of neuroscience and neurology, likely because HD is a neurodegenerative disorder. Publications written in areas such as psychiatry, genetics, and molecular biology also predominated.
Assuntos
Palavras-chave

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Doença de Huntington / Pesquisa Biomédica Tipo de estudo: Diagnostic_studies Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Braz. j. med. biol. res Assunto da revista: BIOLOGIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil

Texto completo: 1 Coleções: 01-internacional Base de dados: LILACS Assunto principal: Doença de Huntington / Pesquisa Biomédica Tipo de estudo: Diagnostic_studies Limite: Humans País/Região como assunto: America do sul / Brasil Idioma: En Revista: Braz. j. med. biol. res Assunto da revista: BIOLOGIA / MEDICINA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Brasil País de publicação: Brasil