Three atypical lethal cases associated with acute Zika virus infection in Suriname
IDCases
; 5: 49-53, July 19, 2016. ilus, tab
Artigo
em Inglês
| MedCarib
| ID: biblio-906540
Biblioteca responsável:
TT5
ABSTRACT
Acute Zika virus infection usually presents with a self-limiting triad of fever, rash and arthritis. There is limited information on severe or lethal cases. We report three cases of lethal acute Zika infection, confirmed with polymerase chain reaction, in adult patients with some co-morbidities. The patients showed rapid clinical deterioration with hemorrhagic and septic shock, and exaggerated acute and innate inflammatory responses with pronounced coagulopathy, and died soon after admission to the hospital. It remains unclear whether the fatal outcomes were due to acute Zika virus infection alone or to the combination with exacerbated underlying prior disease or co-infection. Nonetheless, the severity of these cases implies that increased awareness for atypical presentations of Zika virus infection, and careful clinical assessment of patients with symptoms of Zika, is warranted during current and future outbreaks...(AU)
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MedCarib
Assunto principal:
Infecção por Zika virus
Tipo de estudo:
Estudo diagnóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
América do Sul
/
Caribe Inglês
/
Suriname
Idioma:
Inglês
Revista:
IDCases
Ano de publicação:
2016
Tipo de documento:
Artigo
Instituição/País de afiliação:
Academic Hospital Paramaribo/SR
/
University of Groningen/NL