Una enfermedad multisistemica. Asociación entre enfermedad celiaca y enfermedad tiroidea. Reporte de un caso / A multisystemic disease. Association between celiac disease and thyroid disease. Report of a case

RESUMEN

La enfermedad celíaca (EC) es una enfermedad autoinmune multisistémica que afecta principalmente al intestino delgado. Generalmente se presenta con diarrea, malabsorción y pérdida de peso. A menudo se asocia con trastornos endócrinos autoinmunes tales como enfermedad de tiroides (tiroiditis de Hashimoto) y diabetes mellitus insulinodependiente (tipo 1), enfermedad de Addison autoinmune (insuficiencia suprarrenal) e insuficiencia ovárica. Dicha asociación estaría determinada genéticamente debido a la detección común del antígeno linfocítico humano. Se presenta caso clínico de una niña de 4 años que se interna por diarrea, edema y desnutrición, en la que se diagnostica EC y tiroiditis autoinmune

ABSTRACT

Celiac disease is a multysistemic autoimmune disorder that principally affects the first portion of the small bowel. Diarrhea, abdominal distention and failure to thrive are their most frequent complaints. It is frequently associated with endocrine autoimmune disorders such as autoimmune thyroiditis (Hashimoto Disease), insulin dependent type I diabetes mellitus; Addison's disease and ovaric autoimmune disease, both of them, the latter, causing their respective insufficiencies. That association would be genetically determined since human lymphocytic antigen has been found in both. We present a case of a four-year-old girl who was admitted for diarrhea, edema and malnutrition, in which CD and autoimmune thyroiditis were diagnosed