Potencial of different hydroxyapatites as biomaterials in the bone remodeling
Acta cir. bras
; 33(9): 816-823, Sept. 2018. tab, graf
Artigo
em Inglês
| LILACS
| ID: biblio-973498
Biblioteca responsável:
BR1.1
ABSTRACT
Abstract Purpose:
To analyze the therapeutic potentials of different hydroxyapatites used for the correction of bone defects in rats.Methods:
Forty rats, male, albino wistar, were distributed in 4 groups. They were submitted to a 3.5 mm defect in tibia. They received low purity hydroxyapatite, Strontium hydroxyapatite and hydroxyapatite doped with gallium, having a seven day evaluation time. Histopathology slides were stained with hematoxylin-eosin, for morphological evaluation. Were analyzed inflammatory processes, necrosis, presence of osteoclasts and osteoblasts, presence of the material, presence of white cells, neovascularization and bone neoformation.Results:
It was observed that the groups HAPSr and HAPGa, presented better results of trabecular bone, hyaline cartilage and bone marrow more organized.Conclusion:
There was improvement in the repair of the bone defect produced, showing that these hydroxyapatites are effective osteoinductive, osteoconductive, osteintegrant agents and have biocompatibility, and may be indicated for use in defect repairs.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
LILACS
Assunto principal:
Tíbia
/
Materiais Biocompatíveis
/
Remodelação Óssea
/
Substitutos Ósseos
/
Hidroxiapatitas
Limite:
Animais
Idioma:
Inglês
Revista:
Acta cir. bras
Assunto da revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2018
Tipo de documento:
Artigo
País de afiliação:
Brasil
Instituição/País de afiliação:
UFMS/BR
/
Universidade Federal do Mato Grosso do Sul/BR