Anticuerpos anti-citoplasma de polimorfonuclear neutrófilo en granulomatosis de Wegener, en otras enfermedades autoinmunes y en pacientes hemodializados. / [Anticytoplasm antibodies of polymorphonuclear neutrophils in Wegeners granulomatosis, other autoimmune diseases, and in patients undergoing hemodialysis]

ABSTRACT

Systemic vasculitis are an heterogeneous group of diseases characterized by inflammatory infiltration and necrosis of blood vessel walls. Antineutrophil cytoplasmic antibodies (ANCA) with different immunofluorescent patterns (C or P) have been described as serological markers of some of these diseases and some types of glomerulonephritis. The presence of ANCA by immunofluorescence on normal fixed polymorphonuclear neutrophils was investigated in 182 patients. Results are depicted in Table 1. ANCA was present in 16/17 (94