Vesicular transport: implications for cell polarity
Biocell
; 20(3): 343-353, Dec. 1996.
Article
em En
| BINACIS
| ID: bin-6366
Biblioteca responsável:
BR1.1
ABSTRACT
In polarized cells intracellular sorting of plasma membrane proteins occurs to a large extent at the trans-Golgi network, giving rise to vesicles destined for distinct plasma membrane domains. This review discusses the several pathways, both direct and indirect, which lead to protein incorporation into the correct cell surface, as well as the mechanisms involved. Proteins contain signals which direct their incorporation into the distinct vesicles destined for plasma membrane microdomains. Specific coat proteins are involved in vesicle assembly and are likely to play a role in the generation of discrete vesicle populations. Molecules involved in vesicle docking and fusion may also add specificity to the targeting process.(AU)
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Coleções:
06-national
/
AR
Base de dados:
BINACIS
Assunto principal:
Polaridade Celular
/
Vesículas Revestidas
/
Proteínas de Membrana
Limite:
Animals
Idioma:
En
Revista:
Biocell
Ano de publicação:
1996
Tipo de documento:
Article