Effect endotracheal suction on superoxide dismutase and catalase activity in CABG patients

ABSTRACT

Executing some nursing and medicine activities, may increase the production of Free Radicals of Electrons, which results in a kind of oxidative stresses when Anti-oxidants fail to defend the body So the purpose of this study is to determine the effect of suction with a tube located inside the Trachea on the amount of Oxidative Stress Indexes on C.A.B.G patients. This is a clinical trial study. A number of 35 patients were under CABG and they had a endothrachial tube and were under Mechanical Ventilation. In this method, first blood sampling is performed in 3 times [before and right after the suction and 15 minutes after the suction]. Then, the amount of Catalyse Anti- Oxidants and Super Oxide Dismutase are measured. The results showed that means of Super Oxide Dismutase in periods of before and right after the suction and 15 minutes after the suction had a meaningful differences and a raising trend. [P<0.05]. However in the case of Catalyse in the same mentioned periods there was no significant. Suction is a radical bringing process, which apposes some changes on the activities of Anti-oxidants. When Anti- oxidants fail to defend [the body], oxidative stress emerges. Therefore, necessary amendment programs needed to amend the above-mentioned process according the scientific researches