Importancia del screening de tuberculosis previo al tratamiento con inhibidores del factor de necrosis tumoral alfa / Importance of tuberculosis screening before inhibiting tumour necrosis factor-alpha therapy
Arch. Soc. Esp. Oftalmol
; 88(1): 36-39, ene. 2013. ilus
Article
em Es
| IBECS
| ID: ibc-109505
Biblioteca responsável:
ES1.1
Localização: BNCS
RESUMEN
Introducción: En los últimos años se ha registrado un aumento en la incidencia de infección tuberculosa, debido a la utilización cada vez mayor de fármacos inhibidores del factor de necrosis tumoral alfa (anti-TNF alfa) en el tratamiento de enfermedades inflamatorias. Caso clínico: Se describe el caso de un varón en tratamiento con infliximab (anti-TNF alfa) que desarrolla tuberculosis diseminada con afectación ocular. Conclusión: Es de gran importancia la realización de un screening apropiado para detectar pacientes con riesgo de desarrollar tuberculosis antes de iniciar tratamiento con dichos fármacos. Con este propósito, el QuantiFERON®-TB Gold in Tube (Interferon Gamma Release Assay, IGRA) se presenta como una alternativa de alta sensibilidad y especificidad(AU)
ABSTRACT
Introduction: There has been an increase in the incidence of tuberculosis infection in recent years, due to the increasing use of drugs inhibiting tumour necrosis factor-alpha (anti-TNF alpha) in the treatment of inflammatory diseases. Case report: We report the case of a male patient being treated with infliximab (anti-TNF alpha) who developed disseminated tuberculosis with ocular involvement. Conclusion: It is very important to conduct a proper screening to detect patients at risk for tuberculosis before starting treatment with these drugs. For this purpose, the QuantiFERON®-TB Gold in Tube (Interferon Gamma Release Assay, IGRA) is presented as an alternative screening test with high sensitivity and specificity(AU)
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Coleções:
06-national
/
ES
Base de dados:
IBECS
Assunto principal:
Tuberculose Ocular
/
Fator de Necrose Tumoral alfa
/
Receptores do Fator de Necrose Tumoral
/
Granuloma
Tipo de estudo:
Diagnostic_studies
/
Screening_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
Es
Revista:
Arch. Soc. Esp. Oftalmol
Ano de publicação:
2013
Tipo de documento:
Article