Nuevos compuestos que contienen núcleos 1, 3, 4-­oxadiazol y pirazol-­3-­ona. Sintesis y actividad antimicrobiana "in vitro" / Novel Compounds containing 1, 3, 4-oxadiazole and pyrazole-3-one Nuclei - Synthesis and in vitro Antimicrobial Evaluation

ABSTRACT

New series of heterocycles containing 1,3,4-oxadiazole and pyrazole-3-one moiety have been synthesized and evaluated in vitro against Staphylococus aureus NCCS 2079, Bacillus cereus NCCS 2106, Escherichia coli NCCS 2065, Pseudomanas aeruginosa NCCS 2200, Aspergillus niger NCCS 1196 and Candida albicans NCCS 2106. The compounds demonstrated moderate antimicrobial activity against selected fungal and bacterial strains

RESUMEN

Nuevas series de compuestos heterocíclicos que contienen 1,3,4-oxadiazol y pyrazol-3-ona han sido sintetizadas y evaluadas in-vitro contra Staphylococus aureus NCCS 2079, Bacillus cereus NCCS 2106, Escherichia coli NCCS 2065, Pseudomanas aeruginosa NCCS 2200, Aspergillus niger NCCS 1196 y Candida albicans NCCS 2106. Los compuestos demostraron actividad antimicrobiana moderada contra estirpes fúngicas y bacterianas seleccionadas