Nutrient regulation of enteroendocrine cellular activity linked to cholecystokinin gene expression and secretion
J. physiol. biochem
; 66(1): 85-92, mar. 2010.
Artigo
em Inglês
| IBECS
| ID: ibc-122853
Biblioteca responsável:
ES1.1
Localização: BNCS
RESUMEN
No disponible
ABSTRACT
The hormone cholecystokinin is produced by the enteroendocrine I cells in the intestine, and it plays an important role in a number of physiological processes including digestion and food intake. Recent data suggest that cholecystokinin gene expression and protein secretion are regulated bymacronutrients. The mechanism involves a change in intracellular levels of cAMP and Ca+2, brought about by the activity of a number of nutrient-responsive G protein-coupled receptors, nutrient transporters, ion channels and intracellular enzymes. How these intracellular responses could lead to gene expression and protein secretion are discussed along with new directions for future investigation (AU)
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Colecistocinina
/
Expressão Gênica
/
Células Enteroendócrinas
Limite:
Humanos
Idioma:
Inglês
Revista:
J. physiol. biochem
Ano de publicação:
2010
Tipo de documento:
Artigo
Instituição/País de afiliação:
Moorepark Food Research Centre/Ireland