Study of the prevalence of tumour-related asthenia in Spanish cancer patients
Clin. transl. oncol. (Print)
; 10(6): 351-358, jun. 2008. tab, ilus
Artigo
em Inglês
| IBECS
| ID: ibc-123459
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
INTRODUCTION:
Asthenia is the most prevalent symptom in oncological patients but it is underestimated by the majority of healthcare professionals. The aim of the present study is to estimate the prevalence of tumour-related asthenia in the Spanish population, while defining the associated factors.METHODS:
An epidemiological, multicentre, cross-sectional study was conducted in oncology services from Spain, including 712 cancer patients (58.4+/-13.5 years).RESULTS:
42.5% patients showed asthenia. This prevalence appeared to be tumour-related (p<0.05) and increased among patients with a more advanced stage of disease or with a worsening of performance status (p<0.001). The prevalence of asthenia increased in the presence of the following factors chemotherapy (in the past 52.1% vs. 31.0%; at the time of the study 46.1% vs. 38.2%), symptomatic treatment (in the past 60.4% vs. 39.8%; at the time of the study 61.3% vs. 38.6%), present interferon treatment (100%), anaemia (59.7% vs. 31.3%), dehydration/waterelectrolyte imbalance (58.3% vs. 41.6%), respiratory failure (61.4% vs. 39.7%), liver disease (59.5% vs. 41.3%), malnutrition (76.1% vs. 38.7%), pain (57.7% vs. 27.0%), anxiety (56.1% vs. 38.6%), depression (57.9% vs. 40.0%) and sleep disturbances (51.1% vs. 39.4%). A multivariate logistic regression showed that a model including performance status, patient circumstance, chemotherapy, anaemia, pain and anxiety correctly diagnosed asthenia in 70.9% of cases.CONCLUSIONS:
The physiopathology of tumour-related asthenia remains relatively unknown, despite its high prevalence and considerable quality of life impact. Determining factors related to asthenia in clinical practice can favour the use of concrete treatments and improve the conditions of cancer patients (AU)RESUMEN
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Astenia
/
Estudos Multicêntricos como Assunto
/
Neoplasias
Tipo de estudo:
Ensaio clínico controlado
/
Estudo observacional
/
Estudo de prevalência
/
Estudo prognóstico
/
Fatores de risco
Aspecto:
Preferência do paciente
Limite:
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Europa
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2008
Tipo de documento:
Artigo
Instituição/País de afiliação:
Hospital La Moraleja/Spain
/
Hospital Universitari Vall d´Hebrón/Spain
/
University Hospital Gregorio Marañón/Spain
/
University Hospital La Paz/Spain
/
Valencia General Hospital/Spain