Intimal-medialthickness and carotid arteries lumen in irradiated patients for head and neck cancer: preliminary data of an observational study
Clin. transl. oncol. (Print)
; 15(10): 861-864, oct. 2013. tab, ilus
Artigo
em Inglês
| IBECS
| ID: ibc-127512
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
OBJECTIVES:
To investigate the effect of external beam radiotherapy (EBRT) for head and neck cancer (HNC) the intimal-medial thickness (IMT) and the lumen of the carotid artery.METHODS:
Patients with HNC and an indication for EBRT were enrolled. A carotid artery color Doppler examination was performed before and 6 and 12 months after EBRT.RESULTS:
From 2008 to 2011, 50 patients were enrolled. The mean carotid IMT was 0.9 vs. 1.02 mm before and 6 months after EBRT, respectively (p = 0.0001). The common carotid artery lumen was narrowed without statistical significance, 6 months after EBRT (p = 0.3). 1 year from EBRT, the IMT increase and the lumen reduction were statistically significant (p = 0.001, p = 0.01, respectively). Neurological events (stroke or TIA) were not observed.CONCLUSIONS:
Our data showed a significant IMT increase 6 months from EBRT without a corresponding narrowing of the common carotid lumen while a significant increase 12 months after EBRT (AU)
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Lesões por Radiação
/
Artérias Carótidas
/
Doenças das Artérias Carótidas
/
Túnica Média
/
Espessura Intima-Media Carotídea
/
Neoplasias de Cabeça e Pescoço
Tipo de estudo:
Estudo de etiologia
/
Estudo de avaliação
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Clin. transl. oncol. (Print)
Ano de publicação:
2013
Tipo de documento:
Artigo
Instituição/País de afiliação:
CROB+Italy