Oral health and systemic inflammatory, cardiac and nitroxid biomarkers in hemodialysis patients
Med. oral patol. oral cir. bucal (Internet)
; 22(4): e432-e439, jul. 2017. graf, tab
Artigo
em Inglês
| IBECS
| ID: ibc-164943
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background:
Periodontal diseases have systemic inflammatory effects and have been adversely associated with cardiovascular diseases, which are also the most frequent cause of death in the end-stage renal disease. The aim of this cross-sectional study was to investigate the oral health and serum biomarkers among the hemodialysis (HD) patients in Slovenia. Material andMethods:
111 HD patients were periodontally examined and their sera were assayed for C-reactive protein (CRP), cardiac troponin T (TnT), nitrite/nitrate (NOx) and antibody levels to A. actinomycetemcomitans and P. gingivalis. The association of oral health with systemic response was analyzed with Kruskal-Wallis test, Fishers exact test and multivariate linear regression.Results:
Bleeding on probing without periodontal pockets was present in 5.2%, calculus without periodontal pockets in 42.1%, shallow periodontal pockets in 39.5% and deep periodontal pockets in 13.2% of dentate patients. There were 28.8% edentulous participants. 63.1% of the patients had CRP levels higher than 3 mg/L and 34.2% higher than 10 mg/L. TnT was detectable in all participants, with 25.2% exhibiting levels higher than 100 ng/L. The median level of NOx was 43.1 µmol/L. Participants with higher CRP were more likely to be edentulous and have higher TnT levels. A direct association of oral health with TnT or NOx was not detected.Conclusions:
HD patients in Slovenia have compromised oral health and increased serum inflammatory and cardiac biomarkers. Edentulousness was an independent predictor for the increased CRP, indicating a need for improved dental care to retain the teeth as long as possible (AU)RESUMEN
No disponible
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Contexto em Saúde:
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Hipertensão Arterial
/
Condições e Transtornos Bucais
Base de dados:
IBECS
Assunto principal:
Doenças Periodontais
/
Diálise Renal
/
Inflamação
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
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Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
País/Região como assunto:
Europa
Idioma:
Inglês
Revista:
Med. oral patol. oral cir. bucal (Internet)
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
University Medical Centre Ljubljana/Slovenia
/
University of California/United States
/
University of Helsinki/Filand
/
University of Ljubljana/Slovenia