Type of surgical treatment and recurrence of oral leukoplakia: A retrospective clinical study
Med. oral patol. oral cir. bucal (Internet)
; 22(5): e520-e526, sept. 2017. tab
Artigo
em Inglês
| IBECS
| ID: ibc-166644
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background:
Oral leukoplakia (OL) is the most typical potentially malignant disorder of the oral mucosa. We aimed to evaluate the clinical outcome of oral leukoplakia treated with several types of lasers and with the use of quantic molecular resonance (QMR) lancet, in terms of recurrence rate. Material andMethods:
Eighty-seven previously untreated OL (52 occurring in females and 35 in males, mean age of 59.4 ± 13.9 years) were consecutively submitted to surgical treatment at University Hospital of Parma, Italy, and Hospital de Valongo, Portugal, (1999 to 2012). Interventions were subclassified into 5 groups according to the instrument used for the surgical removal of OL (cold blade - 17; NdYAG 1064nm laser - 14; ErYAG 2940nm laser - 33; CO2 10600nm laser - 15; and QMR scalpel - 8). The mean follow-up period after treatment was 21.6 months (range 1-151 months). The outcome of treatment was scored through the same clinical protocol in the two participating units. Statistical analysis were carried by univariate analysis using chi-square test (or Pearson's test when appropriate).Results:
Recurrences were observed in 24 cases of OL (27.6%). Malignant transformation occurred in one patient (1.1%) after a period of 35 months. Statistical comparison of the 5 surgical treatment modalities showed no differ ences in clinical outcomes nor in the recurrence rate of OL. However, when ErYAG laser group was compared with traditional scalpel, a significantly better outcome in cases treated with ErYAG laser (P = 0.015) was highlighted.Conclusions:
Our results suggests that ErYAG laser could be a promising option for the treatment of OL (AU)RESUMEN
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Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Leucoplasia Oral
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Neoplasias Bucais
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Procedimentos Cirúrgicos Bucais
Tipo de estudo:
Guia de prática clínica
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Estudo observacional
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Fatores de risco
Limite:
Adulto
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Idoso
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Feminino
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Humanos
/
Masculino
Idioma:
Inglês
Revista:
Med. oral patol. oral cir. bucal (Internet)
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
Cooperativa de Ensino Superior Politécnico Universitário (CESPU)/Portugal
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University of Parma/Italy
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Valongo Nossa Senhora da Conceição Hospital/Portugal
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WHO Collaborating Centre for Oral Cancer/United Kingdom