Periodontal, salivary and IL-6 status in rheumatoid arthritis patients. A cross-sectional study
Med. oral patol. oral cir. bucal (Internet)
; 22(5): e595-e600, sept. 2017. tab
Artigo
em Inglês
| IBECS
| ID: ibc-166654
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background:
The aim of this study was to determine whether saliva interleukin-6 (IL-6) levels are elevated in patients with rheumatoid arthritis versus a control group and examine the possible relationship between the oral condition and the risk of RA. Material andMethods:
In 30 patients with RA and 30 healthy controls, different periodontal indices were recorded; sialometric measurements were taken to determine resting whole saliva, stimulated whole saliva and stimulated parotid saliva flow; and the saliva IL-6 levels were measured. Logistic regression analysis was performed, with the presence or absence of RA as dependent variable.Results:
The patients with RA had a greater presence of bacterial plaque, a greater periodontal pocket depth, a larger percentage of medium-sized pockets, and greater periodontal attachment loss compared with the controls. Likewise, a decrease in resting and stimulated saliva flow was observed, together with an increase in saliva IL-6 levels. Logistic regression analysis reported that the plaque index is the principal differentiating factor of patients with RA. Stimulated parotid saliva flow was also significantly correlated to the presence of RA.Conclusions:
The patients with RA showed a greater tendency to develop periodontal disease than the controls, with lower salivary flow and higher levels of IL-6 in saliva (AU)RESUMEN
No disponible
Texto completo:
Disponível
Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Periodontite
/
Artrite Reumatoide
/
Saliva
/
Interleucina-6
Tipo de estudo:
Estudo observacional
/
Estudo de prevalência
/
Fatores de risco
Limite:
Humanos
Idioma:
Inglês
Revista:
Med. oral patol. oral cir. bucal (Internet)
Ano de publicação:
2017
Tipo de documento:
Artigo
Instituição/País de afiliação:
University General Hospital/Spain
/
University of Valencia/Spain