Air pollution and its relationship to lung function among adolescents from Taubate, São Paulo, Brazil
Allergol. immunopatol
; 46(2): 160-166, mar.-abr. 2018. tab, graf
Artigo
em Inglês
| IBECS
| ID: ibc-172175
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Background:
This paper sought to evaluate individual exposure to air pollution by quantifying the carbon in alveolar macrophages (AMs) and its relationship to lung function. We also examined the proximity of participants' residences to the Presidente Dutra highway (PDH) in adolescents with asthma from Taubaté, São Paulo, Brazil.Methods:
This descriptive study examined fifty 13- to 14-year-old adolescents with asthma identified by the International Study of Asthma and Allergies in Childhood (ISAAC) in Taubaté. These adolescents underwent spirometry and sputum induction via the inhalation of 3% hypertonic saline (HSS). Sputum was collected after each nebulisation, and forced expiratory flow in one second (FEV1) was measured. The collected sputum was stored and transported to the laboratory; it was then processed and analysed for ultrafine particles (≤100 nm). This analysis was correlated with the residence location and FEV1 of each adolescent.Results:
A total of 39 adolescents completed the study. The comparison of the carbon fraction within macrophages (CA/MA) showed no differences according to residence in relation to the PDH (p=0.758). After adjustment, a mixed linear model with FEV1 as the dependent variable and CA/MA, location, and evaluation condition as the predictors found that the interactions among the variables were not significant.Conclusions:
T he amount of carbon present within the AMs of adolescents with asthma was not correlated with either lung function or residence location. Evaluations of the topograghy and local climatic conditions in Taubaté should be considered in future studies (AU)RESUMEN
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Asma
/
Poluição do Ar
/
Material Particulado
/
Fuligem
Tipo de estudo:
Estudo prognóstico
Limite:
Adolescente
/
Humanos
País/Região como assunto:
América do Sul
/
Brasil
Idioma:
Inglês
Revista:
Allergol. immunopatol
Ano de publicação:
2018
Tipo de documento:
Artigo
Instituição/País de afiliação:
University of São Paulo/Brazil
/
University of Taubaté (UNITAU)/Brazil