Risk of hospitalization associated with body mass index and weight changes among prevalent haemodialysis patients / Riesgo de hospitalización asociado con el índice de masa corporal y los cambios de peso entre los pacientes de hemodiálisis prevalentes
Nefrología (Madrid)
; 38(5): 520-527, sept.-oct. 2018. tab, graf
Artigo
em Inglês
| IBECS
| ID: ibc-177637
Biblioteca responsável:
ES1.1
Localização: BNCS
RESUMEN
The impact of body mass index (BMI) and body weight on hospitalization rates in haemodialysis patients is unknown. This study hypothesizes that being either underweight or obese is associated with a higher hospitalization rate. Observational study of 6296 European haemodialysis patients with prospective data collection and follow-up every six months for three years (COSMOS study). The risk of being hospitalized was estimated by a time-dependent Cox regression model and the annual risk (incidence rate ratios, IRR) by Poisson regression. We considered weight loss, weight gain and stable weight. Weight change analyses were also performed after patient stratification according to their baseline BMI. A total of 3096 patients were hospitalized at least once with 9731 hospitalizations in total. The hospitalization incidence (fully adjusted IRR 1.28, 95% CI [1.18-1.39]) was higher among underweight patients (BMI < 20 kg/m2) than patients of normal weight (BMI 20-25 kg/m2), while the incidence of overweight (0.88 [0.83-0.93]) and obese patients (≥ 30kg/m2, 0.85 [0.79-0.92]) was lower. Weight gain was associated with a reduced risk of hospitalization. Conversely, weight loss was associated with a higher hospitalization rate, particularly in underweight patients (IRR 2.85 [2.33-3.47]). Underweight haemodialysis patients were at increased risk of hospitalization, while overweight and obese patients were less likely to be hospitalized. Short-term weight loss in underweight individuals was associated with a strikingly high hospitalization rate
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Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Índice de Massa Corporal
/
Diálise Renal
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Insuficiência Renal Crônica
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Hospitalização
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Nefrología (Madrid)
Ano de publicação:
2018
Tipo de documento:
Artigo
Instituição/País de afiliação:
Alessandro Manzoni Hospital/Italy
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Centre Hospitalier FH Manhes/France
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Consiglio Nazionale Research Council/Italy
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Institute Clin Exp Medicine/Czech Republic
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Instituto Biosanitario de Salamanca (IBSAL)/Spain
/
Karolinska Institutet/Sweden
/
Klinikum Coburg/Germany
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RWTH Aachen University/Germany
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UK King's Health Partners (AHSC)/UK
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Universidad de Oviedo/Spain