25-Hydroxyvitamin D levels of children are inversely related to adiposity assessed by body mass index
J. physiol. biochem
; 74(1): 111-118, feb. 2018. tab
Artigo
em Inglês
| IBECS
| ID: ibc-178923
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Vitamin D deficiency is associated with wide range of pathologies. Some evidences have shown that low vitamin D circulating levels in children and adolescent are related to fat mass and obesity. The objectives of the present study were to characterize vitamin D status in children and adolescents and to determine if serum 25-hydroxyvitamin D (25(OH)D) concentration is related to adiposity assessed by body mass index (BMI). Serum 25(OH)D levels were measured by LIAISON method in 471 children and adolescents (2 to 18 years age) and analyzed according to gender, pubertal period, age, and BMI. An overall prevalence of 25(OH)D insufficiency and deficiency was present in the 67.1%. Lower 25(OH)D levels were found in females (25.56 ± 14.03 vs 29.71 ± 17.10 ng ml−1; P = 0.004) and pubertal children (25.52 ± 13.97 vs 29.21 ± 16.83 ng ml−1; P = 0.011). In addition, an inverse relation of BMI and age on 25(OH)D concentrations was observed in children. In conclusion, low vitamin D status was highly prevalent among children and adolescents. Of note, a non-lineal regression model showed that 39.6% of vitamin D levels variability was explained by BMI. These results indicate that adiposity assessed by BMI impacts vitamin D status
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Coleções:
Bases de dados nacionais
/
Espanha
Base de dados:
IBECS
Assunto principal:
Deficiência de Vitamina D
/
Calcifediol
/
25-Hidroxivitamina D 2
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Sobrepeso
/
Adiposidade
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Obesidade Pediátrica
Limite:
Adolescente
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Criança
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Feminino
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Humanos
/
Masculino
País/Região como assunto:
Europa
Idioma:
Inglês
Revista:
J. physiol. biochem
Ano de publicação:
2018
Tipo de documento:
Artigo
Instituição/País de afiliação:
Center for Biomedical Research (UGR)/Spain
/
SERGAS)+Spain
/
Reina Sofia University/Spain
/
University of Santiago de Compostela/Spain
/
University of Vigo/Spain