Evidence for respiratory viruses interactions in asymptomatic preschool-aged children
Allergol. immunopatol
; 47(3): 260-264, mayo-jun. 2019. tab
Article
em En
| IBECS
| ID: ibc-186487
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
Aim: To prospectively evaluate interferences between viruses of the upper respiratory tract in asymptomatic preschool children. Methods: Nasal-pharyngeal swabs from 233 preschool aged children were prospectively collected over four consecutive time periods, during one school year. The samples were tested using a RT-PCR DNA/RNA microarray system for nine respiratory viruses. Results: Respiratory syncytial virus (RSV) was a predictor of the presence of influenza virus (INFL) (OR: 9.12, CI: 1.52-54.75, p = 0.016), and similarly, INFL predicted the presence of RSV (OR: 4.01, CI: 1.14-14.16, p = 0.030). Also, rhinovirus (RV) was a predictor of adenovirus (ADV) presence (OR: 3.66, CI: 1.10-12.14, p = 0.034), and similarly, ADV predicted the presence of RV (OR: 4.05, CI: 1.02-16.05, p = 0.046). No other significant associations between viruses were observed. Conclusion: Our results indicate that respiratory viruses found in carrier stage in asymptomatic children may interact with other viruses and even facilitate their settling in the upper respiratory tract. The pathophysiological role of these interactions is not yet clear
RESUMEN
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Coleções:
06-national
/
ES
Base de dados:
IBECS
Assunto principal:
Orthomyxoviridae
/
Vírus Sinciciais Respiratórios
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Infecções Respiratórias
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Rhinovirus
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Adenoviridae
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Infecções por Vírus Respiratório Sincicial
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Resfriado Comum
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Infecções por Adenoviridae
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Influenza Humana
Limite:
Child, preschool
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Female
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Humans
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Male
País/Região como assunto:
Europa
Idioma:
En
Revista:
Allergol. immunopatol
Ano de publicação:
2019
Tipo de documento:
Article