Risk factors related to oral candidiasis in patients with primary Sjögren's síndrome
Med. oral patol. oral cir. bucal (Internet)
; 25(5): e700-e705, sept. 2020. tab, graf
Article
em En
| IBECS
| ID: ibc-196527
Biblioteca responsável:
ES1.1
Localização: BNCS
ABSTRACT
BACKGROUND:
Candidiasis is the most frequent mycotic infection of the oral cavity. The aim of this study was to investigate the presence of clinical oral candidiasis and Candida albicans yeast in a population diagnosed of primary Sjögren's syndrome (pSS) and to study the possible factors associated with this infection. MATERIAL ANDMETHODS:
An observational cross-sectional study was conducted in 61 pSS patients (60 women, 1 man, mean age 57.64 ± 13.52) where patient based information (demographic and medical, tobacco and alcohol consumption history), intraoral parameters (presence of dentures, clinical signs of candidiasis), salivary analytical information (number of Candida albicans as colony-forming units per millilitre (CFU/mL), salivary pH levels, unstimulated whole saliva (UWS) and stimulated whole saliva (SWS) were collected.RESULTS:
13.1% of pSS patients presented oral signs of candidiasis. Denture stomatitis and angular cheilitis were the most common lesions. 87.5% of patients with clinical candidiasis presented reduced pH levels and salivary flow in both UWS and SWS. A significant statistical negative correlation was found between CFU/mL of Candida albicans and levels of UWS and SWS. A negative correlation was found between pH levels and CFU/mL, although not statistically significant.CONCLUSIONS:
A reduced salivary flow may predispose pSS patients to Candida albicans overgrowth, which may show with clinical signs. Preventive measures are of great importance to avoid and to treat this condition promptlyRESUMEN
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Texto completo:
1
Coleções:
06-national
/
ES
Base de dados:
IBECS
Assunto principal:
Candida albicans
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Candidíase Bucal
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Síndrome de Sjogren
Limite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Med. oral patol. oral cir. bucal (Internet)
Ano de publicação:
2020
Tipo de documento:
Article